Disease Clusters?

Groups of diseases that share a large number of curated genes with each other, computed via label propagation over the shared-gene similarity graph. See also Shared-Gene Disease Pairs for pairwise comparisons.

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Cluster 16

23 diseases · 38 shared-gene connections
23 Diseases
645 Unique genes
0.066 Avg. similarity score
Atopic dermatitis Most-connected disease (8 links)
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Disease Searched: Autoinflammation with episodic fever and immune dysregulation Pinned (dragged)
Node size = connections within this cluster · edge thickness = similarity strength · hover an edge for its details · click a node to select it and show its pairs below (double-click or Ctrl/⌘-click opens the disease page) · drag a node to pin it in place · scroll/pinch to zoom.

Member diseases (most connected first ‐ the cluster's core)

Disease ⇵ Connections in cluster ⇵ Significant partners ⇵ Curated genes ⇵
Atopic dermatitis 8 8 66
Allergic contact dermatitis 7 7 73
Hypersensitivity 7 7 70
Rhinitis 7 7 65
Autoimmune hepatitis 6 6 38
Dermatitis 5 5 38
Eosinophilia 5 5 112
Glomerulonephritis 5 5 97
Urticaria 5 5 46
Behcet disease 3 3 105
Contact dermatitis 3 3 75
Autoinflammation with episodic fever and immune dysregulation 2 2 1
Uveitis 2 2 33
hyper-ige syndrome 6, autosomal dominant, with recurrent infections 2 2 1
Angioedema 1 1 57
Carnosinemia 1 1 1
ITPKB deficiency 1 1 1
Lewis lung carcinoma 1 1 2
Microscopic polyangiitis 1 1 1
fontaine progeroid syndrome 1 1 1
jaberi-elahi syndrome 1 1 1
phosphohydroxylysinuria 1 1 1
systemic lupus erythematosus 17 1 1 1

Top shared genes (genes linked to 2+ member diseases ‐ top 100 shown, download for all)

Gene ⇵ Member diseases ⇵ Linked diseases
IL18 9 / 23 Allergic contact dermatitis, Atopic dermatitis, Autoimmune hepatitis, Behcet disease and 5 more
TNF 9 / 23 Allergic contact dermatitis, Atopic dermatitis, Behcet disease, Dermatitis and 5 more
HLA-DRB1 8 / 23 Angioedema, Autoimmune hepatitis, Behcet disease, Dermatitis and 4 more
IL10 8 / 23 Allergic contact dermatitis, Atopic dermatitis, Autoimmune hepatitis, Behcet disease and 4 more
HLA-DQA1 7 / 23 Autoimmune hepatitis, Dermatitis, Eosinophilia, Glomerulonephritis and 3 more
IL1B 7 / 23 Atopic dermatitis, Behcet disease, Glomerulonephritis, Hypersensitivity and 3 more
IL4 7 / 23 Allergic contact dermatitis, Atopic dermatitis, Autoimmune hepatitis, Behcet disease and 3 more
TGFB1 7 / 23 Atopic dermatitis, Autoimmune hepatitis, Behcet disease, Eosinophilia and 3 more
ALB 6 / 23 Angioedema, Glomerulonephritis, Hypersensitivity, Rhinitis and 2 more
HLA-DQB1 6 / 23 Angioedema, Autoimmune hepatitis, Behcet disease, Hypersensitivity and 2 more
IFNG 6 / 23 Allergic contact dermatitis, Atopic dermatitis, Autoimmune hepatitis, Glomerulonephritis and 2 more
IL13 6 / 23 Atopic dermatitis, Autoimmune hepatitis, Dermatitis, Hypersensitivity and 2 more
IL2 6 / 23 Allergic contact dermatitis, Atopic dermatitis, Autoimmune hepatitis, Behcet disease and 2 more
TLR4 6 / 23 Allergic contact dermatitis, Atopic dermatitis, Behcet disease, Contact dermatitis and 2 more
CYP1A1 5 / 23 Allergic contact dermatitis, Atopic dermatitis, Behcet disease, Contact dermatitis and 1 more
IL6 5 / 23 Atopic dermatitis, Autoimmune hepatitis, Glomerulonephritis, Hypersensitivity and 1 more
CCL2 4 / 23 Autoimmune hepatitis, Behcet disease, Glomerulonephritis, Hypersensitivity
CCR1 4 / 23 Allergic contact dermatitis, Behcet disease, Contact dermatitis, Hypersensitivity
CCR2 4 / 23 Allergic contact dermatitis, Hypersensitivity, Rhinitis, Uveitis
CXCR3 4 / 23 Atopic dermatitis, Contact dermatitis, Glomerulonephritis, Hypersensitivity
EMSY 4 / 23 Atopic dermatitis, Dermatitis, Eosinophilia, Rhinitis
HLA-B 4 / 23 Behcet disease, Dermatitis, Hypersensitivity, Uveitis
IL5 4 / 23 Allergic contact dermatitis, Atopic dermatitis, Autoimmune hepatitis, Eosinophilia
STAT6 4 / 23 Atopic dermatitis, Eosinophilia, hyper-ige syndrome 6, autosomal dominant, with recurrent infections, Urticaria
TLR2 4 / 23 Atopic dermatitis, Behcet disease, Eosinophilia, Rhinitis
AHR 3 / 23 Atopic dermatitis, Behcet disease, Contact dermatitis
CCL24 3 / 23 Atopic dermatitis, Hypersensitivity, Rhinitis
CCL5 3 / 23 Atopic dermatitis, Autoimmune hepatitis, Glomerulonephritis
CCR3 3 / 23 Atopic dermatitis, Behcet disease, Rhinitis
CCR5 3 / 23 Atopic dermatitis, Behcet disease, Uveitis
CLEC16A 3 / 23 Dermatitis, Eosinophilia, Rhinitis
CTLA4 3 / 23 Atopic dermatitis, Autoimmune hepatitis, Behcet disease
DSG1 3 / 23 Dermatitis, Eosinophilia, Hypersensitivity
FLG 3 / 23 Atopic dermatitis, Contact dermatitis, Dermatitis
HLA-DPB1 3 / 23 Angioedema, Autoimmune hepatitis, Urticaria
HNMT 3 / 23 Atopic dermatitis, Rhinitis, Urticaria
IL23R 3 / 23 Behcet disease, Rhinitis, Uveitis
IL2RA 3 / 23 Allergic contact dermatitis, Dermatitis, Glomerulonephritis
ITGB2 3 / 23 Behcet disease, Dermatitis, Hypersensitivity
MBL2 3 / 23 Atopic dermatitis, Behcet disease, Rhinitis
MS4A2 3 / 23 Atopic dermatitis, Hypersensitivity, Rhinitis
NAT2 3 / 23 Allergic contact dermatitis, Atopic dermatitis, Behcet disease
NOD2 3 / 23 Behcet disease, Dermatitis, Rhinitis
SELE 3 / 23 Allergic contact dermatitis, Atopic dermatitis, Urticaria
SERPINE1 3 / 23 Behcet disease, Glomerulonephritis, Rhinitis
SHARPIN 3 / 23 Autoinflammation with episodic fever and immune dysregulation, Dermatitis, Eosinophilia
TNFRSF1A 3 / 23 Behcet disease, Hypersensitivity, Uveitis
TSLP 3 / 23 Atopic dermatitis, Eosinophilia, Hypersensitivity
VDR 3 / 23 Atopic dermatitis, Autoimmune hepatitis, Behcet disease
ABCB1 2 / 23 Behcet disease, Rhinitis
ABI3BP 2 / 23 Angioedema, Urticaria
ALK 2 / 23 Behcet disease, Glomerulonephritis
BANK1 2 / 23 Angioedema, Urticaria
BCL2 2 / 23 Allergic contact dermatitis, Contact dermatitis
BDKRB2 2 / 23 Angioedema, Rhinitis
BDNF 2 / 23 Atopic dermatitis, Rhinitis
CAPSL 2 / 23 Dermatitis, Rhinitis
CASP8 2 / 23 Allergic contact dermatitis, Contact dermatitis
CAT 2 / 23 Behcet disease, Rhinitis
CCL11 2 / 23 Atopic dermatitis, Hypersensitivity
CCL17 2 / 23 Atopic dermatitis, Hypersensitivity
CCL19 2 / 23 Allergic contact dermatitis, Hypersensitivity
CCL26 2 / 23 Eosinophilia, Rhinitis
CCL3 2 / 23 Glomerulonephritis, Hypersensitivity
CCL4 2 / 23 Glomerulonephritis, Hypersensitivity
CCL7 2 / 23 Glomerulonephritis, Hypersensitivity
CDH19 2 / 23 Glomerulonephritis, Microscopic polyangiitis
CLDN1 2 / 23 Atopic dermatitis, Contact dermatitis
CNDP1 2 / 23 Carnosinemia, Glomerulonephritis
CXCL1 2 / 23 Autoimmune hepatitis, Hypersensitivity
CXCL8 2 / 23 Behcet disease, Glomerulonephritis
CYP2D6 2 / 23 Autoimmune hepatitis, Rhinitis
EGFR 2 / 23 Behcet disease, Dermatitis
ERAP1 2 / 23 Behcet disease, Uveitis
F12 2 / 23 Angioedema, Urticaria
F2 2 / 23 Autoimmune hepatitis, Glomerulonephritis
F5 2 / 23 Angioedema, Eosinophilia
FAS 2 / 23 Behcet disease, Glomerulonephritis
FCGR3A 2 / 23 Behcet disease, Rhinitis
GLB1 2 / 23 Atopic dermatitis, Contact dermatitis
GSTM1 2 / 23 Atopic dermatitis, Urticaria
GSTP1 2 / 23 Atopic dermatitis, Contact dermatitis
GTPBP2 2 / 23 Eosinophilia, jaberi-elahi syndrome
HLA-A 2 / 23 Dermatitis, Uveitis
HLF 2 / 23 Angioedema, Urticaria
HMOX1 2 / 23 Contact dermatitis, Rhinitis
ICAM1 2 / 23 Behcet disease, Urticaria
IFT43 2 / 23 Angioedema, Urticaria
IL17A 2 / 23 Hypersensitivity, Rhinitis
IL1A 2 / 23 Allergic contact dermatitis, Behcet disease
IL1RN 2 / 23 Glomerulonephritis, Rhinitis
IL33 2 / 23 Atopic dermatitis, Hypersensitivity
IL4R 2 / 23 Atopic dermatitis, Rhinitis
ITPKB 2 / 23 ITPKB deficiency, Urticaria
KLF13 2 / 23 Eosinophilia, Glomerulonephritis
KNG1 2 / 23 Angioedema, Hypersensitivity
LEP 2 / 23 Autoimmune hepatitis, Rhinitis
MEFV 2 / 23 Behcet disease, Urticaria
MRC1 2 / 23 Allergic contact dermatitis, Rhinitis
MTHFR 2 / 23 Glomerulonephritis, Hypersensitivity
What do these columns mean?
Connections in cluster
How many other members this disease has a shared-gene link to (the node size in the network above). The most-connected diseases are the cluster's core.
Significant partners
How many of those links are statistically significant (FDR q < 0.05).
Curated genes
Distinct curated genes linked to that disease in GeDiPNet.
Member diseases (Top shared genes)
How many of this cluster's diseases are linked to the gene, out of the cluster's total. Genes shared by many members are the most direct explanation of why they group together.
Overlap genes (x / y)
x = genes shared between this cluster and the pathway/GO term; y = that pathway/GO term's total gene count. A higher x relative to y (and to the cluster's own size) means a tighter biological match.
Cluster gene count
Total distinct genes across every disease in this cluster -- the "n" used in the significance test below.
Fold enrichment
Observed overlap divided by the overlap expected by chance, given the cluster's gene count, the pathway/term's size and the gene universe tested. 5× means five times more shared genes than random. Tells strong hits apart when q-values are all vanishingly small.
P-value / FDR q-value
Is this pathway/GO term's overlap with the cluster more than chance? Upper-tail hypergeometric test, Benjamini-Hochberg corrected across every tested pathway/term (prefer the q-value -- it accounts for testing many at once).
Shared genes (Pairs within this cluster)
Number of curated genes the two diseases in that row have in common.
Similarity score (Pairs within this cluster)
Jaccard-based gene overlap between the two specific diseases in that row -- same metric as the main Shared-Gene Disease Pairs page.

Enriched Pathways (why this cluster is grouped, biologically)

Pathway ⇵ Source ⇵ Overlap genes ⇵ Fold enrichment ⇵ P-value ⇵ FDR q-value ⇵
Cytokine-cytokine receptor interaction
IFNG, IL10, IL13, IL17A, IL18, IL4, CCL2, CCL5, CXCL1, IL2, IL22, IL5
 KEGG 86 / 298 5.4× 2.54e-40 1.88e-36 ✓ sig.
Inflammatory bowel disease
HLA-DPB1, HLA-DQB1, HLA-DRB1, IFNG, IL10, IL13, IL17A, IL18, IL4, TLR2, TLR4, IL2
 KEGG 41 / 66 11.6× 7.38e-36 3.04e-32 ✓ sig.
Viral protein interaction with cytokine and cytokine receptor
IL10, IL18, CCL2, CCL5, CXCL1, IL2, IL6, CCR1, CCR5, CXCL8, IL18R1, TNF
 KEGG 48 / 100 8.9× 1.38e-34 4.93e-31 ✓ sig.
Interleukin-4 and Interleukin-13 signaling
HMOX1, IL10, IL13, IL17A, IL18, IL4, PTGS2, CCL2, IL6, TGFB1, IL12A, IL23R
 Reactome 47 / 108 8.1× 1.89e-31 5.38e-28 ✓ sig.
Interleukin-10 signaling
IL10, IL18, PTGS2, CCL2, CCL5, CXCL1, IL6, CCR1, IL12A, CCR5, CXCL8, ICAM1
 Reactome 31 / 47 12.3× 1.42e-28 3.36e-25 ✓ sig.
Chemokine receptors bind chemokines
CCL2, CCL5, CXCL1, CCR1, CCR5, CXCL8, CCR3, CCL27, CXCR3, CCR7, CXCL12, CCL19
 Reactome 31 / 59 9.8× 2.83e-24 4.50e-21 ✓ sig.
Th17 cell differentiation
HLA-DPB1, HLA-DQB1, HLA-DRB1, RUNX1, IFNG, IL17A, IL4, IL2, IL22, IL6, TGFB1, HLA-DQA1
 KEGG 39 / 109 6.7× 1.65e-22 1.88e-19 ✓ sig.
Rheumatoid arthritis
HLA-DPB1, HLA-DQB1, HLA-DRB1, ANGPT1, IFNG, IL17A, IL18, TLR2, TLR4, CCL2, CCL5, CTLA4
 KEGG 34 / 95 6.7× 8.85e-20 6.26e-17 ✓ sig.
JAK-STAT signaling pathway
IFNG, IL10, IL13, IL4, HRAS, IL2, IL22, IL5, IL6, IL9, LEP, STAT4
 KEGG 43 / 168 4.8× 2.53e-18 1.52e-15 ✓ sig.
Lipid and atherosclerosis
IL18, TLR2, TLR4, CCL2, CCL5, CXCL1, HRAS, IL6, FAS, IL12A, APOA1, APOB
 KEGG 47 / 216 4.1× 7.25e-17 3.25e-14 ✓ sig.
Chemokine signaling pathway
CCL2, CCL5, CXCL1, HRAS, CCR1, CCR5, CXCL8, IKBKG, STAT3, ARRB2, CCR3, CCL27
 KEGG 44 / 193 4.2× 1.15e-16 5.01e-14 ✓ sig.
Toxoplasmosis
HLA-DPB1, HLA-DQB1, HLA-DRB1, IFNG, IL10, TLR2, TLR4, TGFB1, HLA-DQA1, IFNGR1, IL12A, CCR5
 KEGG 33 / 112 5.5× 2.55e-16 1.04e-13 ✓ sig.
Tuberculosis
HLA-DPB1, HLA-DQB1, HLA-DRB1, FCGR3A, IFNG, IL10, IL18, MRC1, TLR2, TLR4, IL6, TGFB1
 KEGG 42 / 181 4.3× 2.97e-16 1.19e-13 ✓ sig.
Leishmaniasis
HLA-DPB1, HLA-DQB1, HLA-DRB1, FCGR3A, IFNG, IL10, IL4, PTGS2, TLR2, TLR4, TGFB1, HLA-DQA1
 KEGG 27 / 78 6.4× 1.51e-15 5.48e-13 ✓ sig.
Malaria
IFNG, IL10, IL18, TLR2, TLR4, CCL2, IL6, TGFB1, IL12A, CXCL8, ICAM1, ITGAL
 KEGG 22 / 50 8.2× 1.74e-15 6.21e-13 ✓ sig.

Enriched GO Terms (Biological Process, a second line of biological evidence)

GO term ⇵ GO ID ⇵ Overlap genes ⇵ Fold enrichment ⇵ P-value ⇵ FDR q-value ⇵
immune response
HLA-DPB1, HLA-DQB1, HLA-DRB1, FCGR3A, IFNG, IL10, IL13, IL17A, IL18, IL4, TLR2, TLR4
 GO:0006955 110 / 543 5.9× 1.00e-53 3.55e-49 ✓ sig.
inflammatory response
BDKRB2, KNG1, HRH1, IL13, IL17A, IL18, TLR2, TLR4, CCL2, CCL5, CXCL1, IL22
 GO:0006954 100 / 467 6.2× 4.47e-51 1.05e-46 ✓ sig.
chemotaxis
CCL2, CCL5, CXCL1, HRAS, CCR1, CCR5, CXCL8, CCR3, LECT2, CCL27, CXCL14, CXCR3
 GO:0006935 43 / 161 7.7× 2.07e-26 7.54e-23 ✓ sig.
cytokine-mediated signaling pathway
NUMBL, IL18, CCL2, IL5, IL6, STAT4, LILRA4, CCR1, IFNGR1, IL23R, IL21R, STAT3
 GO:0019221 39 / 145 7.8× 3.49e-24 1.01e-20 ✓ sig.
positive regulation of inflammatory response
IFNG, IL18, TLR2, TLR4, IL2, TGFB1, CCR1, MEFV, SERPINE1, STAT3, TNF, TNFRSF1A
 GO:0050729 35 / 122 8.3× 7.43e-23 1.80e-19 ✓ sig.
antimicrobial humoral immune response mediated by antimicrobial peptide
KNG1, CCL2, CCL5, CXCL1, F2, CXCL8, CCL27, CXCL14, DEFB1, CXCL12, CCL19, CXCL2
 GO:0061844 35 / 124 8.2× 1.36e-22 3.15e-19 ✓ sig.
cellular response to lipopolysaccharide
ABCB1, IL10, IL18, MRC1, TLR4, CCL2, IL6, CCR5, CXCL8, IRF8, NOD2, SERPINE1
 GO:0071222 40 / 187 6.2× 8.95e-21 1.55e-17 ✓ sig.
response to lipopolysaccharide
ABCB1, IL10, IL13, TLR4, IL12A, IL23R, CYP1A1, NOS3, PTPN22, SLC11A1, TNF, IL12RB2
 GO:0032496 37 / 161 6.7× 1.94e-20 3.24e-17 ✓ sig.
positive regulation of type II interferon production
HLA-DPB1, PDE4D, IL18, TLR4, HRAS, IL2, IL12A, IL23R, IL18R1, IRF8, PTPN22, SLC11A1
 GO:0032729 26 / 77 9.8× 2.64e-19 3.64e-16 ✓ sig.
chemokine-mediated signaling pathway
CCL2, CCL5, CCR1, CCR5, CCR3, CXCR3, CXCL12, CCL19, CCR2, CCL11, CCL22, CCL24
 GO:0070098 24 / 64 10.9× 3.68e-19 4.93e-16 ✓ sig.
positive regulation of gene expression
RIMS1, TMEM119, ANGPT1, CLDN3, GRIA1, IFNG, IL13, IL18, IL4, OCLN, TLR2, TLR4
 GO:0010628 59 / 504 3.4× 1.70e-16 1.55e-13 ✓ sig.
positive regulation of tumor necrosis factor production
FCGR3A, IFNG, IL17A, TLR2, TLR4, IL6, LEP, TGFB1, IFNGR1, NOD2, STAT3, IL1A
 GO:0032760 27 / 113 6.9× 1.02e-15 8.09e-13 ✓ sig.
cell surface receptor signaling pathway
BDKRB2, FCGR3A, IFNG, IL18, CCL2, F2, HRAS, LILRA4, CCR1, CCR5, TNFRSF1A, CCR3
 GO:0007166 48 / 373 3.7× 3.32e-15 2.40e-12 ✓ sig.
cell surface receptor signaling pathway via JAK-STAT
IFNG, IL4, CCL2, IL6, LEP, STAT4, IFNGR1, IL23R, STAT3, TNF, TNFRSF1A, CSF2RB
 GO:0007259 21 / 67 9.1× 4.23e-15 3.00e-12 ✓ sig.
eosinophil chemotaxis
CCL2, CCL5, CCL19, CCL11, CCL22, CCL24, CCL26, CCL1, CCL3, CCL4, CCL7, CCL8
 GO:0048245 13 / 20 18.8× 5.44e-15 3.79e-12 ✓ sig.

Pairs within this cluster, by significance

Disease A ⇵ Disease B ⇵ Similarity score ⇵ Shared genes ⇵ P-value ⇵ FDR q-value ⇵
Atopic dermatitis Rhinitis 0.158 18 8.10e-29 2.38e-27 ✓ sig.
Atopic dermatitis Hypersensitivity 0.151 18 3.72e-28 1.06e-26 ✓ sig.
Atopic dermatitis Behcet disease 0.117 18 1.16e-24 2.78e-23 ✓ sig.
Behcet disease Rhinitis 0.110 17 5.51e-23 1.19e-21 ✓ sig.
Hypersensitivity Rhinitis 0.115 14 2.06e-20 4.00e-19 ✓ sig.
Atopic dermatitis Autoimmune hepatitis 0.129 12 3.32e-20 6.39e-19 ✓ sig.
Autoimmune hepatitis Hypersensitivity 0.124 12 7.12e-20 1.35e-18 ✓ sig.
Hypersensitivity Uveitis 0.118 11 1.35e-18 2.39e-17 ✓ sig.
Angioedema Urticaria 0.118 11 7.76e-18 1.32e-16 ✓ sig.
Glomerulonephritis Hypersensitivity 0.091 14 8.48e-18 1.44e-16 ✓ sig.
Autoimmune hepatitis Rhinitis 0.106 10 3.75e-16 5.79e-15 ✓ sig.
Allergic contact dermatitis Atopic dermatitis 0.085 11 1.08e-14 1.52e-13 ✓ sig.
Atopic dermatitis Contact dermatitis 0.076 10 6.85e-13 8.37e-12 ✓ sig.
Allergic contact dermatitis Hypersensitivity 0.075 10 9.57e-13 1.16e-11 ✓ sig.
Autoimmune hepatitis Glomerulonephritis 0.071 9 1.50e-12 1.79e-11 ✓ sig.
Dermatitis Rhinitis 0.083 8 2.86e-12 3.28e-11 ✓ sig.
Dermatitis Hypersensitivity 0.079 8 5.30e-12 5.96e-11 ✓ sig.
Atopic dermatitis Urticaria 0.076 8 1.69e-11 1.82e-10 ✓ sig.
Allergic contact dermatitis Rhinitis 0.069 9 1.88e-11 2.01e-10 ✓ sig.
Allergic contact dermatitis Behcet disease 0.059 10 6.11e-11 6.21e-10 ✓ sig.
Autoimmune hepatitis Urticaria 0.076 6 1.30e-9 1.17e-8 ✓ sig.
Dermatitis Uveitis 0.075 5 1.57e-8 1.24e-7 ✓ sig.
Eosinophilia Rhinitis 0.047 8 2.18e-8 1.70e-7 ✓ sig.
Allergic contact dermatitis Autoimmune hepatitis 0.057 6 2.25e-8 1.75e-7 ✓ sig.
Dermatitis Eosinophilia 0.041 6 2.96e-7 1.92e-6 ✓ sig.
Allergic contact dermatitis Contact dermatitis 0.042 6 1.43e-6 8.18e-6 ✓ sig.
Autoinflammation with episodic fever and immune dysregulation Dermatitis 0.026 1 2.47e-3 3.37e-3 ✓ sig.
ITPKB deficiency Urticaria 0.021 1 2.99e-3 3.95e-3 ✓ sig.
hyper-ige syndrome 6, autosomal dominant, with recurrent infections Urticaria 0.021 1 2.99e-3 3.95e-3 ✓ sig.
Atopic dermatitis hyper-ige syndrome 6, autosomal dominant, with recurrent infections 0.015 1 4.29e-3 5.38e-3 ✓ sig.
Allergic contact dermatitis systemic lupus erythematosus 17 0.014 1 4.74e-3 5.86e-3 ✓ sig.
Carnosinemia Glomerulonephritis 0.010 1 6.30e-3 7.56e-3 ✓ sig.
Glomerulonephritis Microscopic polyangiitis 0.010 1 6.30e-3 7.56e-3 ✓ sig.
Glomerulonephritis phosphohydroxylysinuria 0.010 1 6.30e-3 7.56e-3 ✓ sig.
Eosinophilia jaberi-elahi syndrome 0.009 1 7.27e-3 8.58e-3 ✓ sig.
Autoinflammation with episodic fever and immune dysregulation Eosinophilia 0.009 1 7.27e-3 8.58e-3 ✓ sig.
Eosinophilia fontaine progeroid syndrome 0.009 1 7.27e-3 8.58e-3 ✓ sig.
Contact dermatitis Lewis lung carcinoma 0.013 1 9.72e-3 1.10e-2 ✓ sig.