GeDiPNet

Unlocking Human Gene–Disease Associations with GeDiPNet

Search Genes, Diseases, Pathways, SNPs, and Proteins in One Integrated Platform. Empowering researchers to uncover complex genetic interactions for translational science.

About GeDiPNet - Gene Disease Pathway Networks

GeDiPNet is an open access, unified database on human Gene Disease Pathway Networks. Gene–disease associations within GeDiPNet are compiled from multiple authoritative sources, including DisGeNET, ClinGen, ClinVar, the Human Phenotype Ontology (HPO), OrphaNet, and PsyGeNET. Manually curated to reduce redundancy and minimize data loss. Similar or sub-type disease names are merged into unique terms for efficient analysis.

GeDiPNet offers interlinked data on human genes, single nucleotide polymorphisms (SNPs), diseases, and biological pathways. For each human gene, the database provides high-level annotated information such as gene synonyms, chromosomal location, expression profiles, gene ontology terms, protein-related data, associated SNPs, diseases, and pathways. The data and algorithms available in GeDiPNet can be used for high throughput analysis that can lead to novel insights and hypothesis generation on gene-disease associations and identification of polypharmacological targets.

Citation: Kundu I, Sharma M, Barai RS, Pokar K, Idicula-Thomas S. GeDiPNet: Online resource of curated gene-disease associations for polypharmacological targets discovery. Genes & Diseases, 2023. https://doi.org/10.1016/j.gendis.2022.05.034

Why Use GeDiPNet?

Gene Icon

Genes
12,280

Disease Icon

Diseases
7,292

Pathway Icon

Pathways
2,179

Curated Knowledgebase

Access high-quality gene–disease-pathway data from multiple sources to support comprehensive analysis.

Tools Icon

Dynamic Biological Analysis

Leverage GeDiPNet's advanced analysis tools to uncover enriched pathways, comorbidities, and polypharmacological targets from gene–disease data.

Collaboration Icon

Collaborative Platform

Encouraging interdisciplinary collaboration by enabling open sharing of scientific knowledge.

I want to identify...

enrichment_analysis
Enriched pathways for a gene set
comorbidity
Comorbidity risk for a list of diseases
drug
Polypharmacological targets for a list of diseases
venn-diagram
Common genes and pathways for a list of diseases