1006
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Sirtuin 1 |
SIR2, SIR2L1, SIR2alpha |
Curated: Ankylosing spondylitis, Atherosclerosis, Atrial fibrillation, Autoimmune disease, Bipolar disorder, Brain infarction, Brain neoplasms, Breast neoplasms, Neuronal ceroid lipofuscinosis, Colitis, Congestive heart failure, Degenerative disorder, Demyelinating diseases, Diabetes mellitus, Diabetes mellitus type 2, Diabetic retinopathy, Endocrine system disease, Fatty liver, Fatty liver, alcoholic, Heart disease, Heart failure, Huntington disease, Hypertrophy, Kidney failure, Metabolic syndrome, Mood disorder, Neurodegenerative disorder, Nonalcoholic fatty liver disease, Obesity, Osteosarcoma, Paralysis, Prostatic neoplasms, Schizophrenia, Scleroderma, Systemic sclerosis, Thrombosis, Tooth disease, Ventricular dysfunction, Wallerian degeneration, monogenic diabetes
Unreviewed: 22q13 monosomy syndrome, Actinic keratosis, Acute Kidney Insufficiency, Adenocarcinoma, Adenocarcinoma Of Colon, Adenoma, Adenomatous Polyposis, Adrenoleukodystrophy, Age-related macular degeneration, Alcoholic Fatty Liver, Alcoholic hepatitis, Allergic rhinitis, Alzheimer disease, Amnesia, Amyloidosis, Amyotrophic Lateral Sclerosis, Anaplasia, Androgen-Insensitivity Syndrome, Anemia, Angina pectoris, Angioimmunoblastic T-cell lymphoma, Anhedonia, Ankylosing Spondylitis, Anodontia, Anorexia, Antisocial Personality Disorder, Anxiety Disorder, Aortic Aneurysm, Aortic Valve Sclerosis, Arteriosclerosis, Arthritis, Asthma, Astrocytoma, Atrial Fibrillation, Autism spectrum disorder, Autoimmune Diseases, B-Cell Lymphoma, Behcet disease, Behcet Syndrome, Benign Neoplasm, Bicuspid aortic valve, Bipolar Disorder, Bladder carcinoma, Bladder Neoplasm, Bloom Syndrome, Bone Disease, Borderline personality disorder, Brain disease, Brain Infarction, Brain injuries, Brain Neoplasms, Breast Cancer, Breast Carcinoma, Breast neoplasm, Bronchitis, Bronchopulmonary Dysplasia, Calcinosis, Cap myopathy, Carcinogenesis, Carcinoma, Carcinoma Of The Head And Neck, Cardiac Defects, Cardiomyopathy, Cardiovascular disease, Cardiovascular Diseases, Carotid artery disease, Carotid artery thrombosis, Carotid Atherosclerosis, Cataract, Cerebral Infarction, Cerebrovascular disorder, Cerebrovascular Disorders, Cervical Cancer, Cervical Intraepithelial Neoplasia, Cervical Tumor, Cervix carcinoma, Charcot-Marie-Tooth disease, Childhood obesity, Cholangiocarcinoma, Cholestanol storage disease, Cholestasis, Cholestasis of pregnancy, Cholestatic liver disease, Cholesterol gallstones, Chondrosarcoma, Chronic Obstructive Pulmonary Disease, Cirrhosis, Cleidocranial Dysplasia, Cockayne Syndrome, Cognition disorder, Cognitive disorder, Colon Carcinoma, Colonic neoplasm, Colonic Neoplasms, Colorectal adenoma, Colorectal Cancer, Colorectal neoplasm, Complete Atrioventricular Block, Congenital Chromosomal Disease, Congenital heart defects, Congestive Heart Failure, Coronary Arteriosclerosis, Coronary artery disease, Coronary Heart Disease, Coronary Syndrome, Craniosynostosis, Cystic Fibrosis, Cytochrome-C Oxidase Deficiency, Deafness, Degenerative Diseases, Central Nervous System, Dementia, Demyelinating Diseases, Dermatitis, Diabetes, Diabetes complications, Diabetes Insipidus, Diabetes Mellitus, Diabetes mellitus, type 1, Diabetes mellitus, type 2, Diabetic cardiomyopathy, Diabetic Foot, Diabetic Nephropathy, Diabetic neuropathy, Diabetic Retinopathy, Diffuse Lymphoma, Dilated cardiomyopathy, Disorder Of Eye, Dowling degos disease, Dowling-Degos Disease, Down syndrome, Duane retraction syndrome, Ductal carcinoma, Dwarfism, Dyslipidemias, Ear Diseases, Eczema, Endometrial Cancer, Endometrial carcinoma, Endometrial neoplasm, Endometrial Neoplasms, Endometrioma, Endometriosis, Enterocolitis, Epilepsy, Epiphyseal dysplasia, Epithelial ovarian carcinoma, Esophageal Carcinoma, Esophageal neoplasm, Esophageal squamous cell carcinoma, Esophagus Neoplasm, Fatigue syndrome, Fatty Liver, Fragile X Syndrome, Gastric Cancer, Gaucher disease, Gestational diabetes, Glaucoma, Glioblastoma, Glioma, Glomerulosclerosis, Glycogen Storage Disease, Gout, Gouty arthritis, Graft-Vs-Host Disease, Graves Disease, Hashimoto Disease, Heart Diseases, Heart Failure, Hemangioma, Hemangiosarcoma, Hematologic neoplasm, Hematologic Neoplasms, Hematopoietic Neoplasms, Hemolytic uremic syndrome, Hepatic encephalopathy, Hepatitis c, Hepatoblastoma, Hepatocellular carcinoma, Hereditary breast and ovarian cancer syndrome, Hirschsprung disease, Hodgkin Disease, Huntington Disease, Hypercholesterolemia, Hyperglycemia, Hyperhomocysteinemia, Hyperinsulinism, Hyperlipidemia, Hyperoxia, Hyperphosphatemia, Hyperplasia, Hypersensitivity, Hypertension, Hyperuricemia, Hypothyroidism, Hypoxia, Hypoxic-Ischemic Encephalopathy, Idiopathic pulmonary fibrosis, Iga nephropathy, Immunologic Deficiency Syndromes, Impaired Cognition, Incontinentia pigmenti syndrome, Inflammatory Bowel Disease, Inguinal Hernia, Intermediate coronary syndrome, Intervertebral Disc Degeneration, Intervertebral disc disease, Intervertebral Disc Disorder, Intracranial arteriovenous malformation, Intracranial Neoplasm, Iron Overload, Irritable Bowel Syndrome, Ischemic Stroke, Kaposi Sarcoma, Kidney Disease, Kidney Failure, Kidney neoplasm, Kidney stone, Knee osteoarthritis, Laryngeal Carcinoma, Left Ventricular Hypertrophy, Leukemia, Leukocyte adhesion deficiency, Lewy body disease, Lip and Oral Cavity Carcinoma, Lipid Metabolism Disorders, Liposarcoma, Liver Cancer, Liver carcinoma, Liver Cirrhosis, Liver disease, Liver failure, Liver Fibrosis, Liver neoplasm, Liver neoplasms, Lung adenocarcinoma, Lung Cancer, Lung carcinoma, Lung disease, Lung Diseases, Lung Neoplasms, Lupus Erythematosus, Lupus Nephritis, Lupus Vulgaris, Lymphatic Metastasis, Lymphoblastic Leukemia, Lymphocytic Leukemia, Lymphoid leukemia, Lymphoma, Lymphopenia, Macular degeneration, Major depressive disorder, Male infertility, Malignant Bone Neoplasm, Malignant gastrointestinal tract tumors, Malignant Mesothelioma, Malignant Neoplasm, Malignant neoplasm of mouth, Malnutrition, Mammary Neoplasms, Mandibuloacral Dysostosis, Mandibuloacral dysplasia, Manic Disorder, Marfan Syndrome, MASS syndrome, Medulloblastoma, Melanoma, Mental Depression, Mental Disorders, Metabolic Diseases, Metabolic Syndrome, Metastatic Melanoma, Microvascular angina, Mitochondrial disease, Mitochondrial Diseases, Mitral Valve Prolapse, Mitral Valve Stenosis, Mood Disorder, Motor neuron atrophy, Motor Neuron Disease, Mouth neoplasm, Multiple myeloma, Multiple Sclerosis, Myelodysplastic Syndrome, Myeloid Leukemia, Myocardial Infarction, Myocardial Ischemia, Myopathy, Myotonic dystrophy, Nasal polyposis, Nasopharyngeal Carcinoma, Native American Myopathy, Necrosis, Necrotizing pancreatitis, Neoplasms, Nephritis, Nephrolithiasis, Nephrotic syndrome, Nervous system disease, Nervous System Disorder, Neural Tube Defect, Neuroblastoma, Neurodegenerative Disorders, Neuronal Ceroid Lipofuscinosis, Niemann-Pick Disease, Nijmegen Breakage Syndrome, Non-Alcoholic Fatty Liver Disease, Oculopharyngeal Muscular Dystrophy, Oestrogen Receptor Positive Breast Cancer, Optic Atrophy, Optic neuritis, Oral Mucositis, Oropharyngeal neoplasm, Osteoarthritis, Osteoglophonic dwarfism, Osteoglosphonic dysplasia, Osteopenia, Osteoporosis, Ovarian cancer, Ovarian Carcinoma, Ovarian Epithelial carcinoma, Ovarian Failure, Ovarian neoplasm, Pancreatic adenocarcinoma, Pancreatic cancer, Pancreatic carcinoma, Pancreatic ductal carcinoma, Pancreatic neoplasm, Pancreatitis, Pancytopenia, Papillary thyroid cancer, Papillary thyroid carcinoma, Parkinson disease, Paroxysmal atrial fibrillation, Periapical Periodontitis, Periodontal Diseases, Periodontitis, Peripheral arterial disease, Peroxisomal disorder, Pigmentary Disorder, Reticulate, With Systemic Manifestations, Pituitary adenoma, Pituitary Diseases, Pituitary neoplasm, Pleomorphic adenoma of salivary gland, Pleuritis, Polycystic Ovary Syndrome, Polyneuropathy, Premature aging, Premature Menopause, Progeria, Progesterone Resistance, Prostate cancer, Prostatic intraepithelial neoplasia, Prostatic neoplasm, Prostatic Neoplasms, Psoriasis, Psoriatic Arthritis, Pulmonary arterial hypertension, Pulmonary Emphysema, Pulmonary Fibrosis, Rectal Carcinoma, Renal Carcinoma, Renal cell carcinoma, Renal fibrosis, Renal Glomerular Disease, Renpenning Syndrome, Respiratory Distress Syndrome, Restrictive cardiomyopathy, Retinal degeneration, Retinal detachment, Retinal Diseases, Retinitis Pigmentosa, Retinoblastoma, Rhabdomyosarcoma, Rheumatoid arthritis, Rhinitis, Sarcoma, Sclerosing cholangitis, Scoliosis, Senile Dementia, Senile Plaques, Sepsis, Septicemia, Shared Paranoid Disorder, Sheldon-Hall syndrome, Situs Inversus, Skin cancer, Skin carcinoma, Skin Lesion, Skin Neoplasms, Sleep Apnea, Squamous cell carcinoma, ST Segment Elevation Myocardial Infarction, Stomach Carcinoma, Stomach Neoplasms, Stomatitis, Stress Disorder, Stroke, Subarachnoid hemorrhage, Syndromic microphthalmia, Synovial sarcoma, Systemic lupus erythematosus, T-cell leukemia, T-Cell Lymphoma, T-Cell Lymphoma/Leukemia, Tauopathies, Tendinitis, Teratoma, Thyroid cancer, Thyroid Carcinoma, Thyroid Neoplasm, Thyroiditis, Trichothiodystrophy, Triple negative breast cancer, Triple Negative Breast Neoplasms, Ulcerative colitis, Urinary bladder cancer, Urinary bladder neoplasms, Uterine neoplasm, Uveal melanoma, Uveitis, Van Der Woude Syndrome, Varicocele, Vascular calcification, Vascular disease, Vascular Diseases, Vascular system injury, Vasculitis, Ventricular hypertrophy, Ventricular septal defect, Vitiligo, Wolman disease, Xeroderma Pigmentosum
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1008
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Sirtuin 2 |
SIR2, SIR2L, SIR2L2 |
Curated: Mood disorder
Unreviewed: Adenocarcinoma, Alzheimer disease, Amyotrophic Lateral Sclerosis, Anhedonia, Arteriosclerosis, Arthritis, Asthma, Atherosclerosis, Basal cell carcinoma, Bladder carcinoma, Bladder Neoplasm, Breast Cancer, Breast Carcinoma, Breast neoplasm, Carcinogenesis, Carcinoma, Cardiovascular Diseases, Cerebral Infarction, Cervical Cancer, Cervical Tumor, Cervix carcinoma, Cholangiocarcinoma, Chronic Obstructive Pulmonary Disease, Cirrhosis, Colon Carcinoma, Colonic Neoplasms, Colorectal Cancer, Colorectal neoplasm, Colorectal Neoplasms, Congenital Chromosomal Disease, Congenital Contractural Arachnodactyly, Coronary artery disease, Cystic Fibrosis, Dementia, Diabetes, Diabetes Mellitus, Diabetes mellitus, type 2, Diabetic foot, Diabetic neuropathy, Diabetic retinopathy, Endometrial Cancer, Endometrial carcinoma, Endometrial neoplasm, Fatty Liver, Gastritis, Glioblastoma, Glioma, Hepatocellular carcinoma, Huntington Disease, Hyperglycemia, Hypertension, Impaired Cognition, Inclusion body myopathy, Intellectual developmental disorder, Intervertebral Disc Degeneration, Intervertebral Disc Disorder, Ischemic Stroke, Juvenile arthritis, Kidney disease, Leukemia, Liver carcinoma, Liver Cirrhosis, Liver failure, Liver Fibrosis, Lung Cancer, Lung carcinoma, Lung neoplasms, Lymphatic metastasis, Lymphocytic Leukemia, Lymphoma, Malignant gastrointestinal tract tumors, Malignant Neoplasm, Mammary Neoplasms, Melanoma, Mental Depression, Metabolic Syndrome, Mood Disorder, Multiple myeloma, Multiple Sclerosis, Myeloid leukemia, Myocardial Infarction, Nasopharyngeal Carcinoma, Neoplasms, Nervous System Disorder, Neuroblastoma, Neurodegenerative disorder, Neurodegenerative Disorders, Neurofibromatosis, Non-Alcoholic Fatty Liver Disease, Obesity, Oculopharyngeal Muscular Dystrophy, Osteoarthritis, Osteoporosis, Ovarian cancer, Ovarian Carcinoma, Ovarian Epithelial carcinoma, Ovarian neoplasm, Pancreatic cancer, Pancreatic carcinoma, Pancreatic ductal carcinoma, Pancreatic Neoplasm, Pancreatitis, Parkinson disease, Periapical Periodontitis, Premature aging, Prostate cancer, Prostatic neoplasm, Psoriatic arthritis, Pulmonary Eosinophilia, Renal Carcinoma, Renal cell carcinoma, Renal fibrosis, Rett Syndrome, Rhabdomyosarcoma, Sarcoma, Senile Dementia, Septicemia, Skin cancer, Squamous cell carcinoma, Stomach Carcinoma, Stomach Neoplasms, Stroke, Synovial sarcoma, Thyroid cancer, Urethral Obstruction, Urinary bladder cancer, Uterine neoplasm, Uveal melanoma
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1009
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Sirtuin 3 |
SIR2L3 |
Curated: Benign prostatic hyperplasia, Brain aneurysm, Squamous cell carcinoma, Coronary artery disease, Gestational diabetes, Hypothyroidism, Mouth neoplasms, Obesity, Uterine fibroid
Unreviewed: Acyl CoA Dehydrogenase Deficiency, Alzheimer disease, Amyloidosis, Amyotrophic Lateral Sclerosis, Anodontia, Arteriosclerosis, Arthritis, Atherosclerosis, B-Cell Lymphoma, Basal cell carcinoma, Brain Infarction, Brain neoplasms, Breast Cancer, Breast Carcinoma, Breast neoplasm, Carcinogenesis, Carcinoma, Carcinoma Of The Head And Neck, Cardiomyopathy, Cardiovascular Diseases, Carotid artery disease, Cerebral Infarction, Cervical Cancer, Cervical Intraepithelial Neoplasia, Cervical Tumor, Cervix carcinoma, Cholangiocarcinoma, Chronic Obstructive Pulmonary Disease, Cirrhosis, Cognitive disorder, Colon Carcinoma, Colonic Neoplasms, Colorectal Cancer, Colorectal neoplasm, Congenital Contractural Arachnodactyly, Congestive Heart Failure, Coronary Arteriosclerosis, Coronary Heart Disease, Coronary Thrombosis, Cytochrome-C Oxidase Deficiency, Delirium, Dementia, Amnestic, Cognitive Disorders, Diabetes, Diabetes Mellitus, Diabetes mellitus, type 1, Diabetes mellitus, type 2, Diabetic angiopathies, Diabetic cardiomyopathy, Diabetic foot, Diabetic Nephropathy, Diabetic neuropathy, Diabetic Retinopathy, Diffuse Lymphoma, Dilated cardiomyopathy, Disorder Of Eye, Dyslipidemias, Endometrial Cancer, Endometrial carcinoma, Endometrial neoplasm, Endometriosis, Epilepsy, Esophagus Neoplasm, Fatty Liver, Friedreich Ataxia, Glioblastoma, Glioma, Graft-Vs-Host Disease, Heart disease, Heart Diseases, Heart Failure, Hematologic Neoplasms, Hepatocellular carcinoma, Huntington Disease, Hyperglycemia, Hyperinsulinism, Hyperlipidemia, Hypertension, Hypertensive Nephropathy, Hypoxia, Impaired Cognition, Intervertebral Disc Degeneration, Intrahepatic Cholangiocarcinoma, Ischemic Stroke, Kidney Cancer, Kidney Disease, Kidney Failure, Kidney Neoplasm, Kidney stone, Leiomyoma, Leukemia, Lip and Oral Cavity Carcinoma, Liver carcinoma, Liver Cirrhosis, Liver Fibrosis, Liver neoplasms, Lung adenocarcinoma, Lung carcinoma, Lung disease, Lung neoplasms, Lymphatic metastasis, Lymphocytic Leukemia, Macular dystrophy, Malignant Neoplasm, Malignant neoplasm of mouth, Malignant Neoplasm Of Tongue, Melanoma, Memory Disorders, Metabolic Diseases, Metabolic Syndrome, Metastatic Prostate Carcinoma, Mitochondrial Complex Deficiency, Mitochondrial disease, Mitochondrial Diseases, Monocytic Leukemia, Mood Disorder, Mouth neoplasm, Mouth Neoplasms, Movement disorder, Movement Disorders, Multiple myeloma, Multiple Sclerosis, Myeloid leukemia, Myeloproliferative disorder, Myocardial Infarction, Myocardial Ischemia, Myopathy, Neoplasms, Nephrolithiasis, Neurocognitive Disorders, Neurodegenerative Disorders, Non-Alcoholic Fatty Liver Disease, Optic Atrophy, Osteoarthritis, Osteogenesis imperfecta, Osteoglophonic dwarfism, Osteopenia, Osteoporosis, Ovarian cancer, Ovarian Carcinoma, Ovarian Epithelial carcinoma, Ovarian neoplasm, Pancreatic cancer, Pancreatic carcinoma, Pancreatic ductal carcinoma, Pancreatic Neoplasm, Parkinson disease, Plexiform leiomyoma, Progressive external ophthalmoplegia, Prostate cancer, Prostatic neoplasm, Prostatic Neoplasms, Pulmonary arterial hypertension, Pulmonary Fibrosis, Pulmonary hypertension, Renal Carcinoma, Renal cell carcinoma, Renal fibrosis, Respiratory Distress Syndrome, Retinal Diseases, Rheumatoid arthritis, Scleroderma, Seminoma, Septicemia, Sleep deprivation, Spherocytosis, ST Segment Elevation Myocardial Infarction, Status Epilepticus, Stomach Carcinoma, Stomach Neoplasms, Stroke, Subarachnoid hemorrhage, Teratozoospermia, Thrombosis, Thyroid cancer, Thyroid Carcinoma, Thyroid Neoplasm, Tongue cancer, Triple negative breast cancer, Tubular Aggregate Myopathy, Uterine Fibroids, Uveal melanoma, Variegate porphyria, Vascular disease, Visceral neuropathy, Vitiligo, Vitiligo-associated SYSTEMIC LUPUS ERYTHEMATOSUS
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