Colorectal adenoma

mRNA Editing: C to U Conversion Formation of the Editosome

Wnt signaling pathway Hippo signaling pathway Signaling pathways regulating pluripotency of stem cells Regulation of actin cytoskeleton Cushing syndrome Alzheimer disease Pathways of neurodegeneration - multiple diseases Human papillomavirus infection Pathways in cancer MicroRNAs in cancer Colorectal cancer Endometrial cancer Basal cell carcinoma Breast cancer Hepatocellular carcinoma Gastric cancer Apoptotic cleavage of cellular proteins Degradation of beta-catenin by the destruction complex Beta-catenin phosphorylation cascade Deactivation of the beta-catenin transactivating complex Disassembly of the destruction complex and recruitment of AXIN to the membrane Misspliced GSK3beta mutants stabilize beta-catenin S33 mutants of beta-catenin aren't phosphorylated S37 mutants of beta-catenin aren't phosphorylated S45 mutants of beta-catenin aren't phosphorylated T41 mutants of beta-catenin aren't phosphorylated APC truncation mutants are not K63 polyubiquitinated APC truncation mutants have impaired AXIN binding AXIN missense mutants destabilize the destruction complex Truncations of AMER1 destabilize the destruction complex Ovarian tumor domain proteases +28 more

Rho GTPase cycle

Aldosterone synthesis and secretion Transcriptional misregulation in cancer CREB phosphorylation NGF-stimulated transcription +1 more

Amyotrophic lateral sclerosis Spinocerebellar ataxia Pathways of neurodegeneration - multiple diseases

Wnt signaling pathway Hippo signaling pathway Signaling pathways regulating pluripotency of stem cells Cushing syndrome Alzheimer disease Pathways of neurodegeneration - multiple diseases Human papillomavirus infection Pathways in cancer Colorectal cancer Endometrial cancer Basal cell carcinoma Breast cancer Hepatocellular carcinoma Gastric cancer Degradation of beta-catenin by the destruction complex Beta-catenin phosphorylation cascade TCF dependent signaling in response to WNT Degradation of AXIN Disassembly of the destruction complex and recruitment of AXIN to the membrane Misspliced GSK3beta mutants stabilize beta-catenin S33 mutants of beta-catenin aren't phosphorylated S37 mutants of beta-catenin aren't phosphorylated S45 mutants of beta-catenin aren't phosphorylated T41 mutants of beta-catenin aren't phosphorylated APC truncation mutants have impaired AXIN binding AXIN missense mutants destabilize the destruction complex Truncations of AMER1 destabilize the destruction complex Ub-specific processing proteases RUNX1 regulates estrogen receptor mediated transcription RUNX1 regulates transcription of genes involved in WNT signaling Estrogen-dependent gene expression +28 more

Alzheimer disease

NF-kappa B signaling pathway Osteoclast differentiation B cell receptor signaling pathway Epstein-Barr virus infection Primary immunodeficiency Antigen activates B Cell Receptor (BCR) leading to generation of second messengers +3 more

Cytokine-cytokine receptor interaction TGF-beta signaling pathway Hippo signaling pathway Pathways in cancer Basal cell carcinoma Signaling by BMP Molecules associated with elastic fibres Transcriptional regulation by RUNX2 +5 more

Cytokine-cytokine receptor interaction TGF-beta signaling pathway Hippo signaling pathway Signaling pathways regulating pluripotency of stem cells Thyroid hormone signaling pathway Pathways in cancer Basal cell carcinoma Fluid shear stress and atherosclerosis Molecules associated with elastic fibres Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation +8 more

Cytokine-cytokine receptor interaction TGF-beta signaling pathway Hippo signaling pathway

Hedgehog signaling pathway Axon guidance Myogenesis Activation of SMO +1 more

RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter

Homologous recombination Fanconi anemia pathway HDR through Single Strand Annealing (SSA) HDR through Homologous Recombination (HRR) Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) Resolution of D-loop Structures through Holliday Junction Intermediates Homologous DNA Pairing and Strand Exchange Processing of DNA double-strand break ends Presynaptic phase of homologous DNA pairing and strand exchange Regulation of TP53 Activity through Phosphorylation G2/M DNA damage checkpoint +8 more

FoxO signaling pathway Cell cycle p53 signaling pathway PI3K-Akt signaling pathway Cellular senescence Wnt signaling pathway Hedgehog signaling pathway Hippo signaling pathway Focal adhesion JAK-STAT signaling pathway Prolactin signaling pathway Measles Human papillomavirus infection Human T-cell leukemia virus 1 infection Epstein-Barr virus infection Pathways in cancer Transcriptional misregulation in cancer Viral carcinogenesis MicroRNAs in cancer Cyclin D associated events in G1 Regulation of RUNX1 Expression and Activity +18 more

Adherens junctions interactions

Cell adhesion molecules Adherens junctions interactions

Estrogen-dependent gene expression

PI3K-Akt signaling pathway Focal adhesion ECM-receptor interaction Cytoskeleton in muscle cells Relaxin signaling pathway AGE-RAGE signaling pathway in diabetic complications Protein digestion and absorption Amoebiasis Human papillomavirus infection Pathways in cancer Small cell lung cancer Collagen degradation Extracellular matrix organization Collagen biosynthesis and modifying enzymes Signaling by PDGF Assembly of collagen fibrils and other multimeric structures Integrin cell surface interactions Anchoring fibril formation Crosslinking of collagen fibrils Laminin interactions Non-integrin membrane-ECM interactions NCAM1 interactions Collagen chain trimerization +20 more

HIF-1 signaling pathway Ubiquitin mediated proteolysis Pathways in cancer Renal cell carcinoma Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha Neddylation Antigen processing: Ubiquitination & Proteasome degradation +4 more

Retinol metabolism Metabolic pathways Vitamins RA biosynthesis pathway Defective CYP26B1 causes Radiohumeral fusions with other skeletal and craniofacial anomalies (RHFCA) +2 more

Spinocerebellar ataxia Reelin signalling pathway

Hippo signaling pathway Tight junction Human papillomavirus infection Unblocking of NMDA receptors, glutamate binding and activation RAF/MAP kinase cascade Neurexins and neuroligins +3 more

Cytoskeleton in muscle cells Arrhythmogenic right ventricular cardiomyopathy Keratinization Formation of the cornified envelope +1 more

Measles L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit +4 more

Neddylation Antigen processing: Ubiquitination & Proteasome degradation

Estrogen signaling pathway HSP90 chaperone cycle for steroid hormone receptors (SHR) ESR-mediated signaling

TGF-beta signaling pathway

Phospholipase D signaling pathway Neuroactive ligand-receptor interaction Glutamatergic synapse G alpha (i) signalling events Class C/3 (Metabotropic glutamate/pheromone receptors) +2 more

Other glycan degradation Various types of N-glycan biosynthesis Metabolic pathways

cAMP signaling pathway Hedgehog signaling pathway Pathways in cancer Basal cell carcinoma Ligand-receptor interactions +2 more

Endocytosis Phagosome Cellular senescence Cell adhesion molecules Antigen processing and presentation Natural killer cell mediated cytotoxicity Type I diabetes mellitus Human cytomegalovirus infection Human papillomavirus infection Human T-cell leukemia virus 1 infection Kaposi sarcoma-associated herpesvirus infection Herpes simplex virus 1 infection Epstein-Barr virus infection Human immunodeficiency virus 1 infection Viral carcinogenesis Autoimmune thyroid disease Allograft rejection Graft-versus-host disease Viral myocarditis ER-Phagosome pathway Endosomal/Vacuolar pathway Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell DAP12 interactions Neutrophil degranulation Interferon gamma signaling Interferon alpha/beta signaling Antigen Presentation: Folding, assembly and peptide loading of class I MHC +24 more

Phagosome Cell adhesion molecules Antigen processing and presentation Hematopoietic cell lineage Th1 and Th2 cell differentiation Th17 cell differentiation Intestinal immune network for IgA production Type I diabetes mellitus Leishmaniasis Toxoplasmosis Staphylococcus aureus infection Tuberculosis Influenza A Human T-cell leukemia virus 1 infection Herpes simplex virus 1 infection Epstein-Barr virus infection Asthma Autoimmune thyroid disease Inflammatory bowel disease Systemic lupus erythematosus Rheumatoid arthritis Allograft rejection Graft-versus-host disease Viral myocarditis Downstream TCR signaling Phosphorylation of CD3 and TCR zeta chains Translocation of ZAP-70 to Immunological synapse Generation of second messenger molecules MHC class II antigen presentation PD-1 signaling Interferon gamma signaling +28 more

Phagosome Cell adhesion molecules Antigen processing and presentation Hematopoietic cell lineage Th1 and Th2 cell differentiation Th17 cell differentiation Intestinal immune network for IgA production Type I diabetes mellitus Leishmaniasis Toxoplasmosis Staphylococcus aureus infection Tuberculosis Influenza A Human T-cell leukemia virus 1 infection Herpes simplex virus 1 infection Epstein-Barr virus infection Asthma Autoimmune thyroid disease Inflammatory bowel disease Systemic lupus erythematosus Rheumatoid arthritis Allograft rejection Graft-versus-host disease Viral myocarditis Downstream TCR signaling Phosphorylation of CD3 and TCR zeta chains Translocation of ZAP-70 to Immunological synapse Generation of second messenger molecules MHC class II antigen presentation PD-1 signaling Interferon gamma signaling +28 more

Valine, leucine and isoleucine degradation Butanoate metabolism Metabolic pathways Peroxisome Synthesis of Ketone Bodies +2 more

Inositol phosphate metabolism Metabolic pathways Phosphatidylinositol signaling system B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Synthesis of PIPs at the plasma membrane Synthesis of IP3 and IP4 in the cytosol Downstream TCR signaling PECAM1 interactions Interleukin receptor SHC signaling +8 more

Chemical carcinogenesis - receptor activation

PI3K-Akt signaling pathway Focal adhesion ECM-receptor interaction Toxoplasmosis Amoebiasis Human papillomavirus infection Pathways in cancer Small cell lung cancer Laminin interactions Interleukin-4 and Interleukin-13 signaling MET activates PTK2 signaling +8 more

PI3K-Akt signaling pathway Focal adhesion ECM-receptor interaction Prion disease Toxoplasmosis Amoebiasis Human papillomavirus infection Pathways in cancer Small cell lung cancer Laminin interactions Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) MET activates PTK2 signaling Post-translational protein phosphorylation +10 more

Rap1 signaling pathway Phospholipase D signaling pathway Neuroactive ligand-receptor interaction PI3K-Akt signaling pathway Gap junction Regulation of actin cytoskeleton Pathogenic Escherichia coli infection Pathways in cancer G alpha (q) signalling events G alpha (i) signalling events Lysosphingolipid and LPA receptors +8 more

Wnt signaling pathway Hippo signaling pathway Signaling pathways regulating pluripotency of stem cells Cushing syndrome Alzheimer disease Pathways of neurodegeneration - multiple diseases Human papillomavirus infection Pathways in cancer Colorectal cancer Endometrial cancer Basal cell carcinoma Breast cancer Hepatocellular carcinoma Gastric cancer Degradation of beta-catenin by the destruction complex Beta-catenin phosphorylation cascade TCF dependent signaling in response to WNT Degradation of AXIN Disassembly of the destruction complex and recruitment of AXIN to the membrane Misspliced GSK3beta mutants stabilize beta-catenin S33 mutants of beta-catenin aren't phosphorylated S37 mutants of beta-catenin aren't phosphorylated S45 mutants of beta-catenin aren't phosphorylated T41 mutants of beta-catenin aren't phosphorylated APC truncation mutants have impaired AXIN binding AXIN missense mutants destabilize the destruction complex Truncations of AMER1 destabilize the destruction complex Ub-specific processing proteases RUNX1 regulates estrogen receptor mediated transcription RUNX1 regulates transcription of genes involved in WNT signaling Estrogen-dependent gene expression +28 more