Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
CHRONIC LYMPHOCYTIC LEUKEMIA	EFO_0000095	ACOXL	Unknown	18758461 22700719 23770605 24292274 26956414 28112199 28165464 39024449	GWAS catalog	Beta-oxidation of pristanoyl-CoA
CHRONIC LYMPHOCYTIC LEUKEMIA	EFO_0000095	ACTA2	Unknown	24292274	GWAS catalog	Vascular smooth muscle contraction Apelin signaling pathway Motor proteins +3 more
CHRONIC LYMPHOCYTIC LEUKEMIA	EFO_0000095	ACTRT3	Unknown	39024449	GWAS catalog	—
CHRONIC LYMPHOCYTIC LEUKEMIA	EFO_0000095	APP	Unknown	34290314	GWAS catalog	Serotonergic synapse Alzheimer disease Pathways of neurodegeneration - multiple diseases +16 more
CHRONIC LYMPHOCYTIC LEUKEMIA	EFO_0000095	ARSB	Unknown	26956414	GWAS catalog	Glycosaminoglycan degradation Metabolic pathways Lysosome +5 more
CHRONIC LYMPHOCYTIC LEUKEMIA	EFO_0000095	ARSJ	Unknown	24292274 28165464	GWAS catalog	Glycosphingolipid metabolism The activation of arylsulfatases
CHRONIC LYMPHOCYTIC LEUKEMIA	EFO_0000095	ASCL2	Unknown	23770605	GWAS catalog	—
CHRONIC LYMPHOCYTIC LEUKEMIA	EFO_0000095	BAK1	Unknown	22700719 23770605 24292274 28112199 28165464	GWAS catalog	Platinum drug resistance Protein processing in endoplasmic reticulum Apoptosis +32 more
CHRONIC LYMPHOCYTIC LEUKEMIA	EFO_0000095	BANK1	Unknown	26956414 28165464 40883272	GWAS catalog	B cell receptor signaling pathway
CHRONIC LYMPHOCYTIC LEUKEMIA	EFO_0000095	BCL2	Unknown	23770605 26956414 28165464	GWAS catalog	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +46 more
CHRONIC LYMPHOCYTIC LEUKEMIA	EFO_0000095	BCL2L11	Unknown	26956414	GWAS catalog	EGFR tyrosine kinase inhibitor resistance FoxO signaling pathway PI3K-Akt signaling pathway +13 more
CHRONIC LYMPHOCYTIC LEUKEMIA	EFO_0000095	BMF	Unknown	24292274 26956414 28112199 28165464 39024449 40883272	GWAS catalog	MicroRNAs in cancer BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members Activation of BMF and translocation to mitochondria
CHRONIC LYMPHOCYTIC LEUKEMIA	EFO_0000095	BUB1B	Unknown	24292274 26956414 28165464	GWAS catalog	Cell cycle Human T-cell leukemia virus 1 infection Inactivation of APC/C via direct inhibition of the APC/C complex +9 more
CHRONIC LYMPHOCYTIC LEUKEMIA	EFO_0000095	C11ORF21	Unknown	23770605 24292274 26956414 28165464 40883272	GWAS catalog	—
CHRONIC LYMPHOCYTIC LEUKEMIA	EFO_0000095	CAMK2D	Unknown	24292274 28165464	GWAS catalog	ErbB signaling pathway Calcium signaling pathway cAMP signaling pathway +44 more
CHRONIC LYMPHOCYTIC LEUKEMIA	EFO_0000095	CASP10	Unknown	31407831	GWAS catalog	Apoptosis RIG-I-like receptor signaling pathway TNF signaling pathway +6 more
CHRONIC LYMPHOCYTIC LEUKEMIA	EFO_0000095	CASP8	Unknown	23770605 40883272	GWAS catalog	Platinum drug resistance p53 signaling pathway Apoptosis +53 more
CHRONIC LYMPHOCYTIC LEUKEMIA	EFO_0000095	CCDC18	Unknown	34290314	GWAS catalog	—
CHRONIC LYMPHOCYTIC LEUKEMIA	EFO_0000095	CD70	Unknown	40883272	GWAS catalog	Cytokine-cytokine receptor interaction TNFs bind their physiological receptors
CHRONIC LYMPHOCYTIC LEUKEMIA	EFO_0000095	CFLAR	Unknown	28165464	GWAS catalog	NF-kappa B signaling pathway Autophagy - animal Apoptosis +9 more
CHRONIC LYMPHOCYTIC LEUKEMIA	EFO_0000095	CIB3	Unknown	28112199	GWAS catalog	—
CHRONIC LYMPHOCYTIC LEUKEMIA	EFO_0000095	CIMAP1B	Unknown	28165464 31407831	GWAS catalog	—
CHRONIC LYMPHOCYTIC LEUKEMIA	EFO_0000095	CLPTM1L	Unknown	24292274	GWAS catalog	—
CHRONIC LYMPHOCYTIC LEUKEMIA	EFO_0000095	CSRNP1	Unknown	26956414	GWAS catalog	—
CHRONIC LYMPHOCYTIC LEUKEMIA	EFO_0000095	CXXC1	Unknown	28165464	GWAS catalog	XBP1(S) activates chaperone genes
CHRONIC LYMPHOCYTIC LEUKEMIA	EFO_0000095	DLEU7	Unknown	40883272	GWAS catalog	—
CHRONIC LYMPHOCYTIC LEUKEMIA	EFO_0000095	DMRTA1	Unknown	26956414 39024449	GWAS catalog	—
CHRONIC LYMPHOCYTIC LEUKEMIA	EFO_0000095	DPP6	Unknown	34290314	GWAS catalog	—
CHRONIC LYMPHOCYTIC LEUKEMIA	EFO_0000095	DRD2	Unknown	28165464	GWAS catalog	Rap1 signaling pathway cAMP signaling pathway Neuroactive ligand-receptor interaction +7 more
CHRONIC LYMPHOCYTIC LEUKEMIA	EFO_0000095	DTNB	Unknown	28112199	GWAS catalog	—
CHRONIC LYMPHOCYTIC LEUKEMIA	EFO_0000095	ELL2	Unknown	28112199	GWAS catalog	Viral life cycle - HIV-1 RNA polymerase II transcribes snRNA genes
CHRONIC LYMPHOCYTIC LEUKEMIA	EFO_0000095	ENPP1	Unknown	34290314	GWAS catalog	Purine metabolism Pyrimidine metabolism Starch and sucrose metabolism +7 more
CHRONIC LYMPHOCYTIC LEUKEMIA	EFO_0000095	EOMES	Unknown	26956414 28112199 28165464	GWAS catalog	—
CHRONIC LYMPHOCYTIC LEUKEMIA	EFO_0000095	ETS1	Unknown	31407831	GWAS catalog	Ras signaling pathway Cellular senescence Human T-cell leukemia virus 1 infection +3 more
CHRONIC LYMPHOCYTIC LEUKEMIA	EFO_0000095	EXOC2	Unknown	21131588 28112199 28165464 39024449	GWAS catalog	Ras signaling pathway Salmonella infection Insulin processing +1 more
CHRONIC LYMPHOCYTIC LEUKEMIA	EFO_0000095	EXOC6	Unknown	36273105 40883272	GWAS catalog	Insulin processing VxPx cargo-targeting to cilium
CHRONIC LYMPHOCYTIC LEUKEMIA	EFO_0000095	FABP3	Unknown	28112199	GWAS catalog	PPAR signaling pathway Triglyceride catabolism
CHRONIC LYMPHOCYTIC LEUKEMIA	EFO_0000095	FARP2	Unknown	22700719 23770605 28165464 40883272	GWAS catalog	Rap1 signaling pathway Adherens junction SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
CHRONIC LYMPHOCYTIC LEUKEMIA	EFO_0000095	FAS	Unknown	23770605 24292274 26956414 28165464 39024449 40883272	GWAS catalog	Platinum drug resistance MAPK signaling pathway Cytokine-cytokine receptor interaction +36 more
CHRONIC LYMPHOCYTIC LEUKEMIA	EFO_0000095	FLACC1	Unknown	40883272	GWAS catalog	—
CHRONIC LYMPHOCYTIC LEUKEMIA	EFO_0000095	FLI1	Unknown	31407831	GWAS catalog	Transcriptional misregulation in cancer
CHRONIC LYMPHOCYTIC LEUKEMIA	EFO_0000095	FREM1	Unknown	34290314	GWAS catalog	ECM-receptor interaction
CHRONIC LYMPHOCYTIC LEUKEMIA	EFO_0000095	FTO	Unknown	34290314	GWAS catalog	Reversal of alkylation damage by DNA dioxygenases
CHRONIC LYMPHOCYTIC LEUKEMIA	EFO_0000095	GPR37	Unknown	28165464	GWAS catalog	Parkinson disease Pathways of neurodegeneration - multiple diseases Peptide ligand-binding receptors +1 more
CHRONIC LYMPHOCYTIC LEUKEMIA	EFO_0000095	GRAMD1B	Unknown	18758461 22700719 23770605 24292274 26956414 28112199 28165464 34290314 39024449	GWAS catalog	—
CHRONIC LYMPHOCYTIC LEUKEMIA	EFO_0000095	HAP1	Unknown	34290314	GWAS catalog	GABAergic synapse Amyotrophic lateral sclerosis Huntington disease +1 more
CHRONIC LYMPHOCYTIC LEUKEMIA	EFO_0000095	HDLBP	Unknown	26956414	GWAS catalog	HDL clearance
CHRONIC LYMPHOCYTIC LEUKEMIA	EFO_0000095	HLA-DOB	Unknown	34290314	GWAS catalog	Phagosome Cell adhesion molecules Antigen processing and presentation +22 more
CHRONIC LYMPHOCYTIC LEUKEMIA	EFO_0000095	HLA-DQA1	Unknown	21131588 23770605 26956414 28165464	GWAS catalog	Phagosome Cell adhesion molecules Antigen processing and presentation +28 more
CHRONIC LYMPHOCYTIC LEUKEMIA	EFO_0000095	HLA-DQB1	Unknown	23770605	GWAS catalog	Phagosome Cell adhesion molecules Antigen processing and presentation +28 more

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Lymphocytic leukemia

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