Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
MYOCARDIAL INFARCTION	EFO_0000612 C0027051 MESH:D009203	ABCG8	Unknown	38072966	GWAS catalog	ABC transporters Fat digestion and absorption Bile secretion +5 more
		ABI2	Unknown	38072966	GWAS catalog	Regulation of actin cytoskeleton Regulation of actin dynamics for phagocytic cup formation VEGFA-VEGFR2 Pathway +2 more
		ABI3	Unknown	38072966	GWAS catalog	—
		ABO	Unknown	21239051 26343387 33532862 34594039 38072966 39024449	GWAS catalog	Glycosphingolipid biosynthesis - lacto and neolacto series Glycosphingolipid biosynthesis - globo and isoglobo series Metabolic pathways +1 more
		ABTB3	Unknown	38072966	GWAS catalog	—
		ACAA2	Unknown	38072966	GWAS catalog	Fatty acid elongation Fatty acid degradation Valine, leucine and isoleucine degradation +3 more
		ACAD10	Unknown	30226566 38072966	GWAS catalog	Mitochondrial Fatty Acid Beta-Oxidation
		ACE	Unknown	1328889 8131300	CTD, Disgenet	Renin-angiotensin system Renin secretion Chagas disease +4 more
		ACTA2	Unknown	24358288	CTD, Disgenet	Vascular smooth muscle contraction Apelin signaling pathway Motor proteins +3 more
		ACTRT2	Unknown	33532862	GWAS catalog	—
		ADAMTS7	Unknown	38072966	GWAS catalog	Defective B3GALTL causes Peters-plus syndrome (PpS) O-glycosylation of TSR domain-containing proteins
		ADD1	Unknown	—	Disgenet	Caspase-mediated cleavage of cytoskeletal proteins XBP1(S) activates chaperone genes Miscellaneous transport and binding events
		ADGRL2	Unknown	38072966	GWAS catalog	—
		ADGRL3	Unknown	30226566	GWAS catalog	—
		ADORA1	Unknown	12160945	CTD, Disgenet	cGMP-PKG signaling pathway cAMP signaling pathway Sphingolipid signaling pathway +6 more
		ADORA3	Unknown	12160945 20132822	CTD, Disgenet	cGMP-PKG signaling pathway Sphingolipid signaling pathway Neuroactive ligand-receptor interaction +2 more
		ADRA2B	Unknown	—	Disgenet	cGMP-PKG signaling pathway Neuroactive ligand-receptor interaction Hormone signaling +4 more
		ADRB2	Unknown	—	Disgenet	Calcium signaling pathway cGMP-PKG signaling pathway cAMP signaling pathway +13 more
		AFAP1L2	Unknown	38072966	GWAS catalog	—
		AGER	Unknown	—	Disgenet	Efferocytosis Neutrophil extracellular trap formation AGE-RAGE signaling pathway in diabetic complications +7 more
		AGPAT4	Unknown	38072966	GWAS catalog	Glycerolipid metabolism Glycerophospholipid metabolism Metabolic pathways +2 more
		AGT	Unknown	16413583 1668233	CTD, Disgenet	Phospholipase D signaling pathway Neuroactive ligand-receptor interaction Hormone signaling +18 more
		AGTR1	Unknown	—	Disgenet	Calcium signaling pathway cGMP-PKG signaling pathway Phospholipase D signaling pathway +18 more
		AHDC1	Unknown	33532862 38072966	GWAS catalog	—
		AIF1	Unknown	38072966	GWAS catalog	—
		AKT3	Unknown	35121771	GWAS catalog	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +119 more
		ALDH2	Unknown	30226566 34594039 38072966	Disgenet, GWAS catalog	Glycolysis / Gluconeogenesis Ascorbate and aldarate metabolism Fatty acid degradation +14 more
		ALOX5AP	Unknown	—	Disgenet	Fc epsilon RI signaling pathway Synthesis of 5-eicosatetraenoic acids Synthesis of Leukotrienes (LT) and Eoxins (EX) +1 more
		ANG	Unknown	—	Disgenet	Amyotrophic lateral sclerosis Adherens junctions interactions
		ANGPTL4	Unknown	33532862	GWAS catalog	PPAR signaling pathway Cholesterol metabolism PPARA activates gene expression +2 more
		ANKRD31	Unknown	34594039	GWAS catalog	—
		ANKUB1	Unknown	26708285	GWAS catalog	—
		ANXA4	Unknown	38072966	GWAS catalog	—
		ANXA5	Unknown	—	Disgenet	Platelet degranulation
		AP3D1	Unknown	24916648	GWAS catalog	Lysosome
		APEX1	Unknown	—	Disgenet	Base excision repair Displacement of DNA glycosylase by APEX1 POLB-Dependent Long Patch Base Excision Repair +4 more
		APOA1	Unknown	—	Disgenet	PPAR signaling pathway Fat digestion and absorption Vitamin digestion and absorption +19 more
		APOA4	Unknown	—	Disgenet	Fat digestion and absorption Vitamin digestion and absorption Cholesterol metabolism +1 more
		APOB	Unknown	34594039 38072966	GWAS catalog	Fat digestion and absorption Vitamin digestion and absorption Cholesterol metabolism +20 more
		APOC1	Unknown	26343387 33532862 37947095 39024449 39789286	GWAS catalog	Cholesterol metabolism VLDL assembly VLDL clearance +1 more
		APOE	Unknown	10587578 33532862 34594039 37947095 39024449	CTD, Disgenet, GWAS catalog	Cholesterol metabolism Alzheimer disease Nuclear signaling by ERBB4 +10 more
		APOH	Unknown	—	Disgenet	Cholesterol metabolism Platelet degranulation
		ARFGEF2	Unknown	38072966	GWAS catalog	Endocytosis
		ARHGAP15	Unknown	33532862 38072966	GWAS catalog	Rho GTPase cycle
		ARHGAP25	Unknown	38072966	GWAS catalog	Rho GTPase cycle
		ARHGAP26	Unknown	33532862 38072966	GWAS catalog	Rho GTPase cycle
		ARHGAP42	Unknown	33532862	GWAS catalog	Rho GTPase cycle
		ARHGEF26	Unknown	33532862 38072966	GWAS catalog	Bacterial invasion of epithelial cells Salmonella infection NRAGE signals death through JNK +2 more
		F13A1	Unknown	17393027	CTD, Disgenet	Complement and coagulation cascades Coronavirus disease - COVID-19 Platelet degranulation +2 more
		F7	Unknown	—	CTD, Disgenet	Complement and coagulation cascades Extrinsic Pathway of Fibrin Clot Formation Gamma-carboxylation of protein precursors +2 more
MYOCARDIAL INFARCTION, SUSCEPTIBILITY TO	MONDO:0012039	F13A1	Causal	—	ClinVar	Complement and coagulation cascades Coronavirus disease - COVID-19 Platelet degranulation +2 more
MYOCARDIAL INFARCTION, SUSCEPTIBILITY TO	MONDO:0012039	F7	Causal	—	ClinVar	Complement and coagulation cascades Extrinsic Pathway of Fibrin Clot Formation Gamma-carboxylation of protein precursors +2 more

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Myocardial infarction

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