Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
MEMORY DISORDERS	C0025261 MESH:D008569	ACHE	Unknown	18599028	CTD, Disgenet	Glycerophospholipid metabolism Cholinergic synapse Neurotransmitter clearance +2 more
		AKAP5	Unknown	18711127	CTD, Disgenet	Trafficking of AMPA receptors ROBO receptors bind AKAP5
		APP	Unknown	15364477 18191838 18599028 19664757 19770021 20816828 22484447 23827522 24858312 25213453 25881725 26420483 26480858 27306655 27567873 28448946 29729307 35247505	CTD, Disgenet	Serotonergic synapse Alzheimer disease Pathways of neurodegeneration - multiple diseases +16 more
		AVP	Unknown	11553362	CTD, Disgenet	Phospholipase D signaling pathway Neuroactive ligand-receptor interaction Hormone signaling +12 more
		BCL2	Unknown	17967740	CTD, Disgenet	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +46 more
		CALY	Unknown	30753204	CTD, Disgenet	Dopaminergic synapse
		CHD1	Unknown	30728766	CTD, Disgenet	Estrogen-dependent gene expression
		CHRM1	Unknown	21682298	CTD, Disgenet	Calcium signaling pathway cAMP signaling pathway Neuroactive ligand-receptor interaction +7 more
		CHRNA7	Unknown	18848931	CTD, Disgenet	Calcium signaling pathway Neuroactive ligand-receptor interaction Cholinergic synapse +5 more
		CNR1	Unknown	29294249	CTD, Disgenet	Rap1 signaling pathway Neuroactive ligand-receptor interaction Thermogenesis +3 more
		COMT	Unknown	28195063	CTD, Disgenet	Steroid hormone biosynthesis Tyrosine metabolism Metabolic pathways +4 more
		DRD2	Unknown	21592505	CTD, Disgenet	Rap1 signaling pathway cAMP signaling pathway Neuroactive ligand-receptor interaction +7 more
		GABRA5	Unknown	20180861	CTD, Disgenet	Neuroactive ligand-receptor interaction Retrograde endocannabinoid signaling GABAergic synapse +4 more
		GIT1	Unknown	21499268	CTD, Disgenet	Endocytosis Regulation of actin cytoskeleton Epithelial cell signaling in Helicobacter pylori infection +1 more
		GRPR	Unknown	17097693	CTD, Disgenet	Calcium signaling pathway Neuroactive ligand-receptor interaction Peptide ligand-binding receptors +1 more
		HLA-DPB1	Unknown	14975599	CTD, Disgenet	Phagosome Cell adhesion molecules Antigen processing and presentation +28 more
		HRH3	Unknown	16488453	CTD, Disgenet	Neuroactive ligand-receptor interaction Histamine receptors G alpha (i) signalling events
		HTR1A	Unknown	12591222	CTD, Disgenet	cAMP signaling pathway Neuroactive ligand-receptor interaction Serotonergic synapse +3 more
		HTR2A	Unknown	29294249	CTD, Disgenet	Calcium signaling pathway Neuroactive ligand-receptor interaction Gap junction +4 more
		HTR6	Unknown	19733250	CTD, Disgenet	Calcium signaling pathway cAMP signaling pathway Neuroactive ligand-receptor interaction +4 more
		HTR7	Unknown	21859099	CTD, Disgenet	Ras signaling pathway Calcium signaling pathway Neuroactive ligand-receptor interaction +4 more
		IGF1	Unknown	34632857	CTD, Disgenet	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +35 more
		IGF2	Unknown	21270887	CTD, Disgenet	MAPK signaling pathway Ras signaling pathway Hormone signaling +9 more
		IL1B	Unknown	21290410	CTD, Disgenet	Antifolate resistance MAPK signaling pathway Cytokine-cytokine receptor interaction +47 more
		INS	Unknown	9264093	CTD, Disgenet	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +39 more
		KL	Unknown	25309793 25550330	CTD, Disgenet	Pentose and glucuronate interconversions Ascorbate and aldarate metabolism Metabolic pathways +15 more
		LNPEP	Unknown	11730987	CTD, Disgenet	Renin-angiotensin system Endosomal/Vacuolar pathway Antigen processing: Ubiquitination & Proteasome degradation
		MAGI2	Unknown	25653350	CTD, Disgenet	Rap1 signaling pathway PI3K-Akt signaling pathway
		MAPT	Unknown	12368474 24556215 29203278 29860433	CTD, Disgenet	MAPK signaling pathway Alzheimer disease Parkinson disease +2 more
		MDK	Unknown	19217924	CTD, Disgenet	NOTCH2 Activation and Transmission of Signal to the Nucleus
		MIF	Unknown	20177408	CTD, Disgenet	Tyrosine metabolism Phenylalanine metabolism Metabolic pathways +3 more
		NPY	Unknown	2611661	CTD, Disgenet	cAMP signaling pathway Neuroactive ligand-receptor interaction Adipocytokine signaling pathway +5 more
		NQO2	Unknown	20861374	CTD, Disgenet	Phase I - Functionalization of compounds
		PNOC	Unknown	10401555	CTD, Disgenet	Neuroactive ligand-receptor interaction Hormone signaling Peptide ligand-binding receptors +1 more
		PRKN	Unknown	12915482	CTD, Disgenet	Ubiquitin mediated proteolysis Mitophagy - animal Protein processing in endoplasmic reticulum +8 more
		PRL	Unknown	36100143	CTD, Disgenet	Cytokine-cytokine receptor interaction Neuroactive ligand-receptor interaction Hormone signaling +6 more
		PSEN1	Unknown	25213453 27567873 28448946	CTD, Disgenet	Wnt signaling pathway Notch signaling pathway Neurotrophin signaling pathway +12 more
		REL	Unknown	20477932	CTD, Disgenet	Ras signaling pathway Transcriptional misregulation in cancer Viral carcinogenesis +1 more
		SIGMAR1	Unknown	15451042	CTD	Amyotrophic lateral sclerosis Pathways of neurodegeneration - multiple diseases
		SLC17A6	Unknown	21295146	CTD, Disgenet	Synaptic vesicle cycle Retrograde endocannabinoid signaling Glutamatergic synapse +2 more
		SLC17A7	Unknown	21295146	CTD, Disgenet	Synaptic vesicle cycle Retrograde endocannabinoid signaling Glutamatergic synapse +3 more
		SLC6A3	Unknown	17992686	CTD, Disgenet	Synaptic vesicle cycle Dopaminergic synapse Parkinson disease +7 more
		SLC6A4	Unknown	18661256 18686203	CTD, Disgenet	Synaptic vesicle cycle Serotonergic synapse Serotonin clearance from the synaptic cleft
		SPHK2	Unknown	24859201	CTD, Disgenet	Sphingolipid metabolism Metabolic pathways Calcium signaling pathway +8 more
		STAT3	Unknown	17928813	CTD, Disgenet	EGFR tyrosine kinase inhibitor resistance Chemokine signaling pathway HIF-1 signaling pathway +53 more
		SYP	Unknown	21295146	CTD, Disgenet	—
		VEGFA	Unknown	20801723	CTD, Disgenet	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +30 more
MEMORY IMPAIRMENT	C0233794	MAPT	Causal	—	Disgenet	MAPK signaling pathway Alzheimer disease Parkinson disease +2 more
		SPG7	Causal	—	Disgenet	Processing of SMDT1
		CLCN1	Unknown	—	Disgenet	Stimuli-sensing channels
		DGUOK	Unknown	—	Disgenet	Purine metabolism Metabolic pathways Nucleotide metabolism +1 more

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Memory disorders

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