Status epilepticus

mRNA Splicing - Major Pathway

ABC transporters Bile secretion MicroRNAs in cancer Gastric cancer ABC-family proteins mediated transport +2 more

Antifolate resistance Platinum drug resistance ABC transporters Bile secretion Folate transport and metabolism Heme degradation ABC-family proteins mediated transport Defective ABCC2 causes Dubin-Johnson syndrome +5 more

Cytoskeleton in muscle cells Proteoglycans in cancer Interaction between L1 and Ankyrins COPI-mediated anterograde transport +1 more

Vasopressin-regulated water reabsorption Bile secretion Vasopressin regulates renal water homeostasis via Aquaporins Passive transport by Aquaporins +1 more

Calcium signaling pathway cGMP-PKG signaling pathway cAMP signaling pathway Efferocytosis Cardiac muscle contraction Adrenergic signaling in cardiomyocytes Osteoclast differentiation Thyroid hormone signaling pathway Pancreatic secretion Alzheimer disease Spinocerebellar ataxia Pathways of neurodegeneration - multiple diseases Hypertrophic cardiomyopathy Arrhythmogenic right ventricular cardiomyopathy Dilated cardiomyopathy Diabetic cardiomyopathy Reduction of cytosolic Ca++ levels Ion homeostasis Ion transport by P-type ATPases +16 more

MAPK signaling pathway Ras signaling pathway cAMP signaling pathway PI3K-Akt signaling pathway Neurotrophin signaling pathway Huntington disease Pathways of neurodegeneration - multiple diseases Cocaine addiction Alcoholism Activated NTRK2 signals through PLCG1 Activated NTRK2 signals through FRS2 and FRS3 NTRK2 activates RAC1 +9 more

Autophagy - other Mitophagy - animal Autophagy - animal Apoptosis - multiple species Apelin signaling pathway Alzheimer disease Amyotrophic lateral sclerosis Huntington disease Spinocerebellar ataxia Pathways of neurodegeneration - multiple diseases Shigellosis Kaposi sarcoma-associated herpesvirus infection Macroautophagy Ub-specific processing proteases +11 more

Efferocytosis Necroptosis Neutrophil extracellular trap formation NOD-like receptor signaling pathway Cytosolic DNA-sensing pathway C-type lectin receptor signaling pathway Amyotrophic lateral sclerosis Pathogenic Escherichia coli infection Shigellosis Salmonella infection Pertussis Legionellosis Yersinia infection Influenza A Coronavirus disease - COVID-19 Lipid and atherosclerosis NOD1/2 Signaling Pathway Interleukin-1 processing TP53 Regulates Transcription of Caspase Activators and Caspases The NLRP3 inflammasome The IPAF inflammasome Interleukin-37 signaling Purinergic signaling in leishmaniasis infection +20 more

Platinum drug resistance MAPK signaling pathway p53 signaling pathway Efferocytosis Apoptosis Apoptosis - multiple species Cytosolic DNA-sensing pathway Natural killer cell mediated cytotoxicity IL-17 signaling pathway TNF signaling pathway Serotonergic synapse Non-alcoholic fatty liver disease AGE-RAGE signaling pathway in diabetic complications Alcoholic liver disease Alzheimer disease Parkinson disease Amyotrophic lateral sclerosis Huntington disease Prion disease Pathways of neurodegeneration - multiple diseases Epithelial cell signaling in Helicobacter pylori infection Pathogenic Escherichia coli infection Salmonella infection Pertussis Legionellosis Toxoplasmosis Amoebiasis Tuberculosis Hepatitis C Hepatitis B Measles Human cytomegalovirus infection Influenza A Human papillomavirus infection Kaposi sarcoma-associated herpesvirus infection Herpes simplex virus 1 infection Epstein-Barr virus infection Human immunodeficiency virus 1 infection Pathways in cancer Viral carcinogenesis Proteoglycans in cancer MicroRNAs in cancer Colorectal cancer Small cell lung cancer Viral myocarditis Lipid and atherosclerosis Activation of caspases through apoptosome-mediated cleavage Apoptotic cleavage of cellular proteins SMAC, XIAP-regulated apoptotic response Apoptosis induced DNA fragmentation Signaling by Hippo NADE modulates death signalling Caspase-mediated cleavage of cytoskeletal proteins Apoptotic cleavage of cell adhesion proteins Caspase activation via Dependence Receptors in the absence of ligand Other interleukin signaling +53 more

Platinum drug resistance p53 signaling pathway Apoptosis Apoptosis - multiple species Necroptosis Toll-like receptor signaling pathway NOD-like receptor signaling pathway RIG-I-like receptor signaling pathway Cytosolic DNA-sensing pathway C-type lectin receptor signaling pathway IL-17 signaling pathway TNF signaling pathway Non-alcoholic fatty liver disease Alcoholic liver disease Alzheimer disease Huntington disease Pathways of neurodegeneration - multiple diseases Pathogenic Escherichia coli infection Salmonella infection Legionellosis Chagas disease Toxoplasmosis Tuberculosis Hepatitis C Hepatitis B Measles Human cytomegalovirus infection Influenza A Human papillomavirus infection Kaposi sarcoma-associated herpesvirus infection Herpes simplex virus 1 infection Epstein-Barr virus infection Human immunodeficiency virus 1 infection Pathways in cancer Viral carcinogenesis Viral myocarditis Lipid and atherosclerosis Apoptotic cleavage of cellular proteins Caspase activation via Death Receptors in the presence of ligand NOD1/2 Signaling Pathway TRIF-mediated programmed cell death Caspase-mediated cleavage of cytoskeletal proteins Regulation by c-FLIP RIPK1-mediated regulated necrosis CASP8 activity is inhibited TNFR1-induced proapoptotic signaling Regulation of TNFR1 signaling CLEC7A/inflammasome pathway Regulation of necroptotic cell death Dimerization of procaspase-8 Activation, myristolyation of BID and translocation to mitochondria Apoptotic execution phase FasL/ CD95L signaling TRAIL signaling TLR3-mediated TICAM1-dependent programmed cell death NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 +53 more

Tryptophan metabolism Glyoxylate and dicarboxylate metabolism Metabolic pathways Carbon metabolism FoxO signaling pathway Peroxisome Longevity regulating pathway Longevity regulating pathway - multiple species Amyotrophic lateral sclerosis Pathways of neurodegeneration - multiple diseases Chemical carcinogenesis - reactive oxygen species Detoxification of Reactive Oxygen Species Neutrophil degranulation Peroxisomal protein import +11 more

Cytokine-cytokine receptor interaction Viral protein interaction with cytokine and cytokine receptor Chemokine signaling pathway NOD-like receptor signaling pathway IL-17 signaling pathway TNF signaling pathway AGE-RAGE signaling pathway in diabetic complications Yersinia infection Chagas disease Malaria Human cytomegalovirus infection Influenza A Herpes simplex virus 1 infection Coronavirus disease - COVID-19 Rheumatoid arthritis Lipid and atherosclerosis Fluid shear stress and atherosclerosis Chemokine receptors bind chemokines ATF4 activates genes in response to endoplasmic reticulum stress Interleukin-10 signaling Interleukin-4 and Interleukin-13 signaling +18 more

Cytokine-cytokine receptor interaction Viral protein interaction with cytokine and cytokine receptor Chemokine signaling pathway Toll-like receptor signaling pathway Chagas disease Human cytomegalovirus infection Rheumatoid arthritis Lipid and atherosclerosis Chemokine receptors bind chemokines Interleukin-10 signaling +7 more

Cytokine-cytokine receptor interaction Viral protein interaction with cytokine and cytokine receptor Chemokine signaling pathway Intestinal immune network for IgA production Chemokine receptors bind chemokines G alpha (i) signalling events +3 more

Cytokine-cytokine receptor interaction Viral protein interaction with cytokine and cytokine receptor Chemokine signaling pathway Beta defensins Chemokine receptors bind chemokines G alpha (i) signalling events Interleukin-10 signaling +4 more

Cytokine-cytokine receptor interaction Viral protein interaction with cytokine and cytokine receptor Chemokine signaling pathway Human cytomegalovirus infection Kaposi sarcoma-associated herpesvirus infection Viral carcinogenesis Chemokine receptors bind chemokines G alpha (i) signalling events +5 more

Cytokine-cytokine receptor interaction Viral protein interaction with cytokine and cytokine receptor Chemokine signaling pathway Chemokine receptors bind chemokines G alpha (i) signalling events +2 more

Cytokine-cytokine receptor interaction Viral protein interaction with cytokine and cytokine receptor Chemokine signaling pathway Kaposi sarcoma-associated herpesvirus infection Viral carcinogenesis Chemokine receptors bind chemokines G alpha (i) signalling events +4 more

Cytokine-cytokine receptor interaction Viral protein interaction with cytokine and cytokine receptor Chemokine signaling pathway Intestinal immune network for IgA production Chemokine receptors bind chemokines G alpha (i) signalling events +3 more

Cytokine-cytokine receptor interaction NF-kappa B signaling pathway Cell adhesion molecules Toll-like receptor signaling pathway Intestinal immune network for IgA production Malaria Toxoplasmosis Human T-cell leukemia virus 1 infection Epstein-Barr virus infection Transcriptional misregulation in cancer Asthma Autoimmune thyroid disease Systemic lupus erythematosus Allograft rejection Primary immunodeficiency Viral myocarditis Lipid and atherosclerosis Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell TNFR2 non-canonical NF-kB pathway TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway +17 more

Cell adhesion molecules Arrhythmogenic right ventricular cardiomyopathy Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Adherens junctions interactions Myogenesis Post-translational protein phosphorylation +3 more

Rap1 signaling pathway Neuroactive ligand-receptor interaction Thermogenesis Retrograde endocannabinoid signaling Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events +3 more

cAMP signaling pathway Neuroactive ligand-receptor interaction Hormone signaling Long-term depression Cushing syndrome Alcoholism Class B/2 (Secretin family receptors) G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production +6 more

Cytoskeleton in muscle cells Hypertrophic cardiomyopathy Arrhythmogenic right ventricular cardiomyopathy Dilated cardiomyopathy Viral myocarditis Striated Muscle Contraction +3 more

Necroptosis Alzheimer disease Hepatitis C Measles Influenza A Human papillomavirus infection Kaposi sarcoma-associated herpesvirus infection Herpes simplex virus 1 infection Epstein-Barr virus infection Coronavirus disease - COVID-19 Viral carcinogenesis ISG15 antiviral mechanism Inhibition of PKR +10 more

Mitophagy - animal Autophagy - animal Protein processing in endoplasmic reticulum Apoptosis Non-alcoholic fatty liver disease Alzheimer disease Parkinson disease Amyotrophic lateral sclerosis Prion disease Pathways of neurodegeneration - multiple diseases Hepatitis C Measles Herpes simplex virus 1 infection Lipid and atherosclerosis PERK regulates gene expression +12 more

Mitophagy - animal Autophagy - animal Protein processing in endoplasmic reticulum Apoptosis Non-alcoholic fatty liver disease Alzheimer disease Parkinson disease Amyotrophic lateral sclerosis Prion disease Pathways of neurodegeneration - multiple diseases Hepatitis C Measles Influenza A Herpes simplex virus 1 infection Lipid and atherosclerosis L13a-mediated translational silencing of Ceruloplasmin expression PERK regulates gene expression ABC-family proteins mediated transport Translation initiation complex formation Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Recycling of eIF2:GDP +20 more

Cytokine-cytokine receptor interaction HIF-1 signaling pathway Hormone signaling Efferocytosis PI3K-Akt signaling pathway JAK-STAT signaling pathway Hematopoietic cell lineage Pathways in cancer Regulation of gene expression by Hypoxia-inducible Factor Erythropoietin activates Phosphoinositide-3-kinase (PI3K) Erythropoietin activates RAS +8 more

Endocrine resistance MAPK signaling pathway cAMP signaling pathway Apoptosis Osteoclast differentiation Toll-like receptor signaling pathway IL-17 signaling pathway Th1 and Th2 cell differentiation Th17 cell differentiation T cell receptor signaling pathway B cell receptor signaling pathway TNF signaling pathway Circadian entrainment Cholinergic synapse Dopaminergic synapse Estrogen signaling pathway Prolactin signaling pathway Oxytocin signaling pathway Relaxin signaling pathway Parathyroid hormone synthesis, secretion and action Non-alcoholic fatty liver disease Growth hormone synthesis, secretion and action Amphetamine addiction Pathogenic Escherichia coli infection Salmonella infection Pertussis Yersinia infection Leishmaniasis Chagas disease Hepatitis B Measles Human T-cell leukemia virus 1 infection Kaposi sarcoma-associated herpesvirus infection Human immunodeficiency virus 1 infection Coronavirus disease - COVID-19 Pathways in cancer Chemical carcinogenesis - receptor activation Chemical carcinogenesis - reactive oxygen species Colorectal cancer Breast cancer Choline metabolism in cancer PD-L1 expression and PD-1 checkpoint pathway in cancer Rheumatoid arthritis Lipid and atherosclerosis Fluid shear stress and atherosclerosis Oxidative Stress Induced Senescence Senescence-Associated Secretory Phenotype (SASP) FCERI mediated MAPK activation Activation of the AP-1 family of transcription factors Interleukin-4 and Interleukin-13 signaling TP53 Regulates Transcription of DNA Repair Genes Estrogen-dependent gene expression NGF-stimulated transcription Estrogen-dependent nuclear events downstream of ESR-membrane signaling +51 more

Sphingolipid metabolism Metabolic pathways Lysosome Glycosphingolipid metabolism +1 more

L1CAM interactions

MAPK signaling pathway Calcium signaling pathway PI3K-Akt signaling pathway RAF/MAP kinase cascade RET signaling +2 more

cAMP signaling pathway Neuroactive ligand-receptor interaction Circadian entrainment Long-term potentiation Retrograde endocannabinoid signaling Glutamatergic synapse Dopaminergic synapse Long-term depression Amyotrophic lateral sclerosis Huntington disease Spinocerebellar ataxia Pathways of neurodegeneration - multiple diseases Cocaine addiction Amphetamine addiction Nicotine addiction Activation of AMPA receptors Trafficking of GluR2-containing AMPA receptors Unblocking of NMDA receptors, glutamate binding and activation +15 more

Calcium signaling pathway FoxO signaling pathway Phospholipase D signaling pathway Neuroactive ligand-receptor interaction Gap junction Long-term potentiation Retrograde endocannabinoid signaling Glutamatergic synapse Long-term depression Taste transduction Estrogen signaling pathway Spinocerebellar ataxia Pathways of neurodegeneration - multiple diseases G alpha (q) signalling events Class C/3 (Metabotropic glutamate/pheromone receptors) Neurexins and neuroligins +13 more

Calcium signaling pathway Phospholipase D signaling pathway Neuroactive ligand-receptor interaction Gap junction Long-term potentiation Retrograde endocannabinoid signaling Glutamatergic synapse Alzheimer disease Huntington disease Pathways of neurodegeneration - multiple diseases G alpha (q) signalling events Class C/3 (Metabotropic glutamate/pheromone receptors) Neurexins and neuroligins +10 more

Porphyrin metabolism Metabolic pathways HIF-1 signaling pathway Ferroptosis Mineral absorption Pathways in cancer MicroRNAs in cancer Chemical carcinogenesis - reactive oxygen species Hepatocellular carcinoma Fluid shear stress and atherosclerosis Heme degradation Interleukin-4 and Interleukin-13 signaling Iron uptake and transport Insertion of tail-anchored proteins into the endoplasmic reticulum membrane +11 more

MAPK signaling pathway VEGF signaling pathway Amoebiasis VEGFA-VEGFR2 Pathway AUF1 (hnRNP D0) binds and destabilizes mRNA MAPK6/MAPK4 signaling Extra-nuclear estrogen signaling +4 more

Cytokine-cytokine receptor interaction Interleukin-10 signaling Interleukin-1 signaling

Endocrine resistance MAPK signaling pathway ErbB signaling pathway cAMP signaling pathway Mitophagy - animal Apoptosis Wnt signaling pathway Osteoclast differentiation Focal adhesion Tight junction Toll-like receptor signaling pathway NOD-like receptor signaling pathway C-type lectin receptor signaling pathway IL-17 signaling pathway Th1 and Th2 cell differentiation Th17 cell differentiation T cell receptor signaling pathway B cell receptor signaling pathway TNF signaling pathway Neurotrophin signaling pathway GnRH signaling pathway Estrogen signaling pathway Oxytocin signaling pathway Relaxin signaling pathway Non-alcoholic fatty liver disease AGE-RAGE signaling pathway in diabetic complications Cocaine addiction Amphetamine addiction Epithelial cell signaling in Helicobacter pylori infection Pathogenic Escherichia coli infection Shigellosis Salmonella infection Pertussis Yersinia infection Leishmaniasis Chagas disease Hepatitis B Measles Human T-cell leukemia virus 1 infection Kaposi sarcoma-associated herpesvirus infection Epstein-Barr virus infection Human immunodeficiency virus 1 infection Coronavirus disease - COVID-19 Pathways in cancer Viral carcinogenesis Chemical carcinogenesis - receptor activation Chemical carcinogenesis - reactive oxygen species Colorectal cancer Renal cell carcinoma Breast cancer Choline metabolism in cancer PD-L1 expression and PD-1 checkpoint pathway in cancer Inflammatory bowel disease Rheumatoid arthritis Lipid and atherosclerosis Fluid shear stress and atherosclerosis Pre-NOTCH Transcription and Translation Oxidative Stress Induced Senescence Senescence-Associated Secretory Phenotype (SASP) FCERI mediated MAPK activation Activation of the AP-1 family of transcription factors MAPK6/MAPK4 signaling TP53 Regulates Transcription of DNA Repair Genes Regulation of PTEN gene transcription Estrogen-dependent gene expression WNT5:FZD7-mediated leishmania damping +63 more

Osteoclast differentiation TNF signaling pathway Growth hormone synthesis, secretion and action SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Interleukin-4 and Interleukin-13 signaling NGF-stimulated transcription +3 more

MAPK signaling pathway Osteoclast differentiation IL-17 signaling pathway Parathyroid hormone synthesis, secretion and action Estrogen-dependent gene expression NGF-stimulated transcription +3 more

Taste transduction Protein digestion and absorption Phase 4 - resting membrane potential

cGMP-PKG signaling pathway Vascular smooth muscle contraction Insulin secretion Renin secretion Salivary secretion Pancreatic secretion Ca2+ activated K+ channels +4 more

Virion - Hepatitis viruses Virion - Lassa virus and SFTS virus Autophagy - animal Lysosome Phagosome Tuberculosis Platelet degranulation Neutrophil degranulation +5 more

MAPK signaling pathway cGMP-PKG signaling pathway Apelin signaling pathway Oxytocin signaling pathway Parathyroid hormone synthesis, secretion and action Transcriptional misregulation in cancer Fluid shear stress and atherosclerosis Transcriptional activation of mitochondrial biogenesis Circadian Clock Myogenesis +7 more

MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway Calcium signaling pathway Cytokine-cytokine receptor interaction PI3K-Akt signaling pathway Apoptosis Neurotrophin signaling pathway Inflammatory mediator regulation of TRP channels NGF processing Frs2-mediated activation ARMS-mediated activation Retrograde neurotrophin signalling TRKA activation by NGF PI3K/AKT activation NFG and proNGF binds to p75NTR NADE modulates death signalling NRIF signals cell death from the nucleus p75NTR recruits signalling complexes NF-kB is activated and signals survival Axonal growth stimulation +18 more

Arginine biosynthesis Arginine and proline metabolism Metabolic pathways Calcium signaling pathway Hormone signaling Phagosome Apelin signaling pathway Circadian entrainment Long-term depression Relaxin signaling pathway Salivary secretion Alzheimer disease Amyotrophic lateral sclerosis Pathways of neurodegeneration - multiple diseases Hypertrophic cardiomyopathy Arrhythmogenic right ventricular cardiomyopathy Dilated cardiomyopathy Viral myocarditis ROS and RNS production in phagocytes Nitric oxide stimulates guanylate cyclase Ion homeostasis +18 more

Arginine biosynthesis Arginine and proline metabolism Metabolic pathways Calcium signaling pathway HIF-1 signaling pathway Peroxisome Apelin signaling pathway Relaxin signaling pathway Alzheimer disease Amyotrophic lateral sclerosis Pathways of neurodegeneration - multiple diseases Pertussis Leishmaniasis Chagas disease Toxoplasmosis Amoebiasis Tuberculosis Pathways in cancer Small cell lung cancer ROS and RNS production in phagocytes Nitric oxide stimulates guanylate cyclase Interleukin-4 and Interleukin-13 signaling Peroxisomal protein import Inhibition of nitric oxide production +21 more

MAPK signaling pathway Ras signaling pathway PI3K-Akt signaling pathway Neurotrophin signaling pathway NTF3 activates NTRK3 signaling Activated NTRK3 signals through PLCG1 Activated NTRK3 signals through PI3K +4 more