Colonic neoplasms

ABC transporters

Purine metabolism Alanine, aspartate and glutamate metabolism Metabolic pathways Nucleotide metabolism Biosynthesis of cofactors Purine ribonucleoside monophosphate biosynthesis +3 more

ATP-dependent chromatin remodeling

cGMP-PKG signaling pathway cAMP signaling pathway Phototransduction Activation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade +2 more

Cell adhesion molecules

Cytoskeleton in muscle cells Protein digestion and absorption Collagen degradation Extracellular matrix organization Collagen biosynthesis and modifying enzymes Signaling by PDGF Assembly of collagen fibrils and other multimeric structures Integrin cell surface interactions Non-integrin membrane-ECM interactions ECM proteoglycans NCAM1 interactions MET activates PTK2 signaling Collagen chain trimerization +10 more

Synthesis of PA

Apoptotic cleavage of cell adhesion proteins Keratinization Formation of the cornified envelope

G0 and Early G1

Cell-extracellular matrix interactions

NRAGE signals death through JNK Rho GTPase cycle G alpha (12/13) signalling events

Ras signaling pathway Chemokine signaling pathway Hormone signaling PI3K-Akt signaling pathway Apelin signaling pathway Circadian entrainment Retrograde endocannabinoid signaling Glutamatergic synapse Cholinergic synapse Serotonergic synapse GABAergic synapse Dopaminergic synapse Olfactory transduction Relaxin signaling pathway Morphine addiction Alcoholism Human cytomegalovirus infection Kaposi sarcoma-associated herpesvirus infection Human immunodeficiency virus 1 infection Pathways in cancer Activation of G protein gated Potassium channels Glucagon signaling in metabolic regulation G-protein activation Glucagon-like Peptide-1 (GLP1) regulates insulin secretion ADP signalling through P2Y purinoceptor 12 G beta:gamma signalling through PI3Kgamma Prostacyclin signalling through prostacyclin receptor Adrenaline,noradrenaline inhibits insulin secretion Ca2+ pathway G alpha (q) signalling events G alpha (12/13) signalling events G beta:gamma signalling through PLC beta G alpha (s) signalling events ADP signalling through P2Y purinoceptor 1 G alpha (i) signalling events G alpha (z) signalling events Glucagon-type ligand receptors Thromboxane signalling through TP receptor Vasopressin regulates renal water homeostasis via Aquaporins Thrombin signalling through proteinase activated receptors (PARs) Presynaptic function of Kainate receptors Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding G beta:gamma signalling through BTK G beta:gamma signalling through CDC42 Extra-nuclear estrogen signaling ADORA2B mediated anti-inflammatory cytokines production Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits +44 more

GnRH secretion HCN channels

Glycosaminoglycan degradation Metabolic pathways Lysosome HS-GAG degradation CS/DS degradation MPS II - Hunter syndrome +3 more

Inositol phosphate metabolism Metabolic pathways Calcium signaling pathway Phosphatidylinositol signaling system Synthesis of IP3 and IP4 in the cytosol +2 more

MAPK signaling pathway

Miscellaneous transport and binding events

MAPK signaling pathway Ras signaling pathway PI3K-Akt signaling pathway Neurotrophin signaling pathway NTF3 activates NTRK3 signaling Activated NTRK3 signals through PLCG1 Activated NTRK3 signals through PI3K +4 more

mRNA surveillance pathway mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs +2 more

Focal adhesion

Signaling pathways regulating pluripotency of stem cells

Chemokine signaling pathway Kaposi sarcoma-associated herpesvirus infection NRAGE signals death through JNK Rho GTPase cycle G alpha (12/13) signalling events +2 more

Ras signaling pathway PPARA activates gene expression

RHO GTPases Activate Rhotekin and Rhophilins

TGF-beta signaling pathway Hippo signaling pathway Signaling by BMP Downregulation of TGF-beta receptor signaling SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Ub-specific processing proteases +3 more

mRNA surveillance pathway Tight junction Transport of Mature mRNA Derived from an Intronless Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs +4 more

Pre-NOTCH Transcription and Translation Oxidative Stress Induced Senescence Oncogene Induced Senescence Ca2+ pathway Post-transcriptional silencing by small RNAs TP53 Regulates Metabolic Genes MAPK6/MAPK4 signaling Transcriptional Regulation by VENTX Regulation of RUNX1 Expression and Activity RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function Regulation of PTEN mRNA translation Competing endogenous RNAs (ceRNAs) regulate PTEN translation Transcriptional Regulation by MECP2 Estrogen-dependent gene expression NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux +12 more

Complement and coagulation cascades Platelet degranulation Intrinsic Pathway of Fibrin Clot Formation Degradation of the extracellular matrix Rho GTPase cycle HDL assembly +3 more

Vascular smooth muscle contraction Apelin signaling pathway Motor proteins Relaxin signaling pathway Smooth Muscle Contraction NOTCH4 Intracellular Domain Regulates Transcription +3 more