Disease Clusters?

Groups of diseases that share a large number of curated genes with each other, computed via label propagation over the shared-gene similarity graph. See also Shared-Gene Disease Pairs for pairwise comparisons.

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Cluster 3

49 diseases · 145 shared-gene connections
49 Diseases
797 Unique genes
0.111 Avg. similarity score
Arrhythmogenic right ventricular cardiomyopathy Most-connected disease (20 links)
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Disease Pinned (dragged)
Node size = connections within this cluster · edge thickness = similarity strength · hover an edge for its details · click a node to select it and show its pairs below (double-click or Ctrl/⌘-click opens the disease page) · drag a node to pin it in place · scroll/pinch to zoom.

Member diseases (most connected first ‐ the cluster's core)

Disease ⇵ Connections in cluster ⇵ Significant partners ⇵ Curated genes ⇵
Arrhythmogenic right ventricular cardiomyopathy 20 20 52
Left ventricular noncompaction cardiomyopathy 15 15 38
Wolff-parkinson-white syndrome 15 15 51
Conduction disorder of the heart 14 14 24
Long qt syndrome 12 12 102
Cardiomyopathy 11 11 244
Arrhythmogenic right ventricular dysplasia 10 10 15
Cardiac arrest 10 10 26
Catecholaminergic polymorphic ventricular tachycardia 10 10 20
Dilated cardiomyopathy 10 10 273
Left ventricular disease 10 10 66
Ventricular fibrillation 10 10 36
Brugada syndrome 9 9 63
Cardiac conduction disease 8 8 9
Hereditary bundle branch system defect 7 7 7
Hypertrophic cardiomyopathy 7 7 256
Sick sinus syndrome 7 7 18
Restrictive cardiomyopathy 6 6 23
Atrioventricular block 5 5 17
Cardiac arrhythmia 5 5 98
Paroxysmal familial ventricular fibrillation 5 5 5
Polymorphic catecholaminergic ventricular tachycardia 5 5 15
dilated cardiomyopathy 1BB 5 5 1
dilated cardiomyopathy 1CC 5 5 1
dilated cardiomyopathy 1JJ 5 5 1
Atrial flutter 4 4 81
Atrial tachyarrhythmia, infra-hisian cardiac conduction disease 4 4 1
Barth syndrome 4 4 1
Hereditary atrial fibrillation 4 4 24
Myofibrillar myopathy 4 4 12
dilated cardiomyopathy 1Z 4 4 1
familial isolated arrhythmogenic right ventricular dysplasia 4 4 1
intrinsic cardiomyopathy 4 4 1
Bronchial disease 3 3 18
cardiomyopathy, dilated, 2e 3 3 1
dilated cardiomyopathy 1HH 3 3 1
dilated cardiomyopathy 1I 3 3 1
dilated cardiomyopathy 1M 3 3 1
dilated cardiomyopathy 1Y 3 3 1
sick sinus syndrome 2, autosomal dominant 3 3 1
Vici syndrome 2 2 1
lissencephaly 10 2 2 1
5-oxoprolinase deficiency 1 1 1
Congenital right-sided heart lesions 1 1 1
FNIP1-associated syndrome 1 1 1
Hypertrophy 1 1 49
cardiomyopathy, dilated, 2h 1 1 1
hypokalemic alkalosis, familial, with specific renal tubulopathy 1 1 1
myofibrillar myopathy 8 1 1 1

Top shared genes (genes linked to 2+ member diseases ‐ top 100 shown, download for all)

Gene ⇵ Member diseases ⇵ Linked diseases
SCN5A 21 / 49 Arrhythmogenic right ventricular cardiomyopathy, Arrhythmogenic right ventricular dysplasia, Atrial flutter, Brugada syndrome and 17 more
TTN 19 / 49 Arrhythmogenic right ventricular cardiomyopathy, Arrhythmogenic right ventricular dysplasia, Atrial flutter, Atrioventricular block and 15 more
DSP 18 / 49 Arrhythmogenic right ventricular cardiomyopathy, Arrhythmogenic right ventricular dysplasia, Brugada syndrome, Cardiac arrest and 14 more
RYR2 17 / 49 Arrhythmogenic right ventricular cardiomyopathy, Arrhythmogenic right ventricular dysplasia, Brugada syndrome, Cardiac arrest and 13 more
MYH6 16 / 49 Arrhythmogenic right ventricular cardiomyopathy, Atrial flutter, Cardiac arrest, Cardiac arrhythmia and 12 more
PKP2 14 / 49 Arrhythmogenic right ventricular cardiomyopathy, Arrhythmogenic right ventricular dysplasia, Brugada syndrome, Cardiac arrhythmia and 10 more
TRPM4 14 / 49 Arrhythmogenic right ventricular cardiomyopathy, Atrioventricular block, Brugada syndrome, Cardiac arrest and 10 more
ANK2 13 / 49 Arrhythmogenic right ventricular cardiomyopathy, Brugada syndrome, Cardiac arrest, Cardiac arrhythmia and 9 more
LMNA 13 / 49 Arrhythmogenic right ventricular cardiomyopathy, Atrioventricular block, Cardiac arrhythmia, Cardiac conduction disease and 9 more
DSG2 12 / 49 Arrhythmogenic right ventricular cardiomyopathy, Arrhythmogenic right ventricular dysplasia, Cardiac arrest, Cardiomyopathy and 8 more
HCN4 12 / 49 Arrhythmogenic right ventricular cardiomyopathy, Atrial flutter, Brugada syndrome, Cardiac arrest and 8 more
MYH7 12 / 49 Arrhythmogenic right ventricular cardiomyopathy, Arrhythmogenic right ventricular dysplasia, Cardiac arrhythmia, Cardiomyopathy and 8 more
CACNA1C 11 / 49 Brugada syndrome, Cardiac arrhythmia, Cardiomyopathy, Conduction disorder of the heart and 7 more
JUP 11 / 49 Arrhythmogenic right ventricular cardiomyopathy, Arrhythmogenic right ventricular dysplasia, Cardiomyopathy, Conduction disorder of the heart and 7 more
MYBPC3 11 / 49 Arrhythmogenic right ventricular cardiomyopathy, Brugada syndrome, Cardiomyopathy, Catecholaminergic polymorphic ventricular tachycardia and 7 more
CASQ2 10 / 49 Atrial flutter, Cardiac arrhythmia, Cardiomyopathy, Catecholaminergic polymorphic ventricular tachycardia and 6 more
KCNH2 10 / 49 Atrial flutter, Brugada syndrome, Cardiac arrhythmia, Cardiomyopathy and 6 more
FLNC 9 / 49 Arrhythmogenic right ventricular cardiomyopathy, Cardiac arrhythmia, Cardiomyopathy, Conduction disorder of the heart and 5 more
KCNJ2 9 / 49 Brugada syndrome, Cardiac arrhythmia, Catecholaminergic polymorphic ventricular tachycardia, Hereditary atrial fibrillation and 5 more
LDB3 9 / 49 Arrhythmogenic right ventricular cardiomyopathy, Arrhythmogenic right ventricular dysplasia, Cardiomyopathy, Dilated cardiomyopathy and 5 more
RBM20 9 / 49 Arrhythmogenic right ventricular cardiomyopathy, Cardiomyopathy, Conduction disorder of the heart, Dilated cardiomyopathy and 5 more
SCN1B 9 / 49 Brugada syndrome, Cardiac arrhythmia, Cardiac conduction disease, Cardiomyopathy and 5 more
ABCC9 8 / 49 Arrhythmogenic right ventricular cardiomyopathy, Brugada syndrome, Cardiomyopathy, Dilated cardiomyopathy and 4 more
ACTC1 8 / 49 Arrhythmogenic right ventricular cardiomyopathy, Cardiomyopathy, Dilated cardiomyopathy, Hypertrophic cardiomyopathy and 4 more
BAG3 8 / 49 Arrhythmogenic right ventricular dysplasia, Atrioventricular block, Cardiomyopathy, Dilated cardiomyopathy and 4 more
CACNB2 8 / 49 Arrhythmogenic right ventricular cardiomyopathy, Brugada syndrome, Cardiac arrest, Cardiac conduction disease and 4 more
CEP85L 8 / 49 Arrhythmogenic right ventricular cardiomyopathy, Atrial flutter, Cardiac arrest, Cardiac arrhythmia and 4 more
DSC2 8 / 49 Arrhythmogenic right ventricular cardiomyopathy, Arrhythmogenic right ventricular dysplasia, Cardiomyopathy, Dilated cardiomyopathy and 4 more
LAMA4 8 / 49 Arrhythmogenic right ventricular cardiomyopathy, Brugada syndrome, Cardiomyopathy, Catecholaminergic polymorphic ventricular tachycardia and 4 more
NEXN 8 / 49 Arrhythmogenic right ventricular cardiomyopathy, Cardiomyopathy, Dilated cardiomyopathy, dilated cardiomyopathy 1CC and 4 more
NKX2-5 8 / 49 Atrial flutter, Atrioventricular block, Dilated cardiomyopathy, Hereditary atrial fibrillation and 4 more
TNNT2 8 / 49 Arrhythmogenic right ventricular cardiomyopathy, Cardiomyopathy, Dilated cardiomyopathy, Hypertrophic cardiomyopathy and 4 more
ACTN2 7 / 49 Arrhythmogenic right ventricular cardiomyopathy, Cardiomyopathy, Dilated cardiomyopathy, Hypertrophic cardiomyopathy and 3 more
AKAP9 7 / 49 Brugada syndrome, Cardiac arrest, Dilated cardiomyopathy, Hypertrophic cardiomyopathy and 3 more
DMD 7 / 49 Arrhythmogenic right ventricular cardiomyopathy, Cardiomyopathy, Conduction disorder of the heart, Dilated cardiomyopathy and 3 more
JPH2 7 / 49 Cardiomyopathy, cardiomyopathy, dilated, 2e, Dilated cardiomyopathy, Hypertrophic cardiomyopathy and 3 more
KCNQ1 7 / 49 Brugada syndrome, Cardiac arrhythmia, Conduction disorder of the heart, Hereditary atrial fibrillation and 3 more
PLN 7 / 49 Arrhythmogenic right ventricular cardiomyopathy, Cardiac arrest, Cardiac arrhythmia, Cardiomyopathy and 3 more
SCN10A 7 / 49 Atrial flutter, Atrioventricular block, Brugada syndrome, Cardiac arrhythmia and 3 more
TBX5 7 / 49 Atrial flutter, Atrioventricular block, Brugada syndrome, Cardiac arrhythmia and 3 more
TMEM43 7 / 49 Arrhythmogenic right ventricular cardiomyopathy, Arrhythmogenic right ventricular dysplasia, Cardiomyopathy, Dilated cardiomyopathy and 3 more
TNNI3 7 / 49 Arrhythmogenic right ventricular cardiomyopathy, Cardiomyopathy, Dilated cardiomyopathy, Hypertrophic cardiomyopathy and 3 more
TPM1 7 / 49 Arrhythmogenic right ventricular cardiomyopathy, Cardiomyopathy, Dilated cardiomyopathy, dilated cardiomyopathy 1Y and 3 more
AGT 6 / 49 Cardiac arrhythmia, Cardiomyopathy, Hypertrophic cardiomyopathy, Hypertrophy and 2 more
CTNNA3 6 / 49 Arrhythmogenic right ventricular cardiomyopathy, Arrhythmogenic right ventricular dysplasia, Cardiomyopathy, Dilated cardiomyopathy and 2 more
DES 6 / 49 Arrhythmogenic right ventricular cardiomyopathy, Atrioventricular block, Dilated cardiomyopathy, dilated cardiomyopathy 1I and 2 more
DPP6 6 / 49 Cardiac arrest, Dilated cardiomyopathy, Long qt syndrome, Paroxysmal familial ventricular fibrillation and 2 more
DTNA 6 / 49 Cardiac arrhythmia, Cardiomyopathy, Dilated cardiomyopathy, Hypertrophic cardiomyopathy and 2 more
KCNE1 6 / 49 Arrhythmogenic right ventricular cardiomyopathy, Cardiomyopathy, Dilated cardiomyopathy, Hereditary atrial fibrillation and 2 more
KCNE2 6 / 49 Cardiac arrhythmia, Cardiomyopathy, Dilated cardiomyopathy, Hereditary atrial fibrillation and 2 more
MYL3 6 / 49 Arrhythmogenic right ventricular cardiomyopathy, Cardiomyopathy, Dilated cardiomyopathy, Hypertrophic cardiomyopathy and 2 more
MYPN 6 / 49 Cardiomyopathy, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Left ventricular disease and 2 more
NEBL 6 / 49 Cardiac arrest, Cardiac arrhythmia, Cardiomyopathy, Dilated cardiomyopathy and 2 more
PITX2 6 / 49 Atrial flutter, Cardiac arrhythmia, Dilated cardiomyopathy, Hereditary atrial fibrillation and 2 more
PRDM16 6 / 49 Cardiomyopathy, Dilated cardiomyopathy, Left ventricular disease, Left ventricular noncompaction cardiomyopathy and 2 more
PRKAG2 6 / 49 Arrhythmogenic right ventricular cardiomyopathy, Cardiomyopathy, Dilated cardiomyopathy, Hypertrophic cardiomyopathy and 2 more
SNTA1 6 / 49 Brugada syndrome, Dilated cardiomyopathy, Long qt syndrome, Sick sinus syndrome and 2 more
SYNE2 6 / 49 Atrial flutter, Cardiac arrhythmia, Dilated cardiomyopathy, Left ventricular disease and 2 more
VCL 6 / 49 Cardiomyopathy, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Long qt syndrome and 2 more
ANKRD1 5 / 49 Brugada syndrome, Cardiomyopathy, Dilated cardiomyopathy, Hypertrophic cardiomyopathy and 1 more
CALM3 5 / 49 Cardiac arrhythmia, Cardiomyopathy, Catecholaminergic polymorphic ventricular tachycardia, Long qt syndrome and 1 more
CDKN1A 5 / 49 Atrial flutter, Cardiomyopathy, Dilated cardiomyopathy, Hypertrophic cardiomyopathy and 1 more
KCNJ5 5 / 49 Atrial flutter, Hereditary atrial fibrillation, Hypertrophic cardiomyopathy, Long qt syndrome and 1 more
KCNJ8 5 / 49 Brugada syndrome, Cardiac arrest, Cardiac arrhythmia, Long qt syndrome and 1 more
MYH7B 5 / 49 Brugada syndrome, Cardiomyopathy, Dilated cardiomyopathy, Hypertrophic cardiomyopathy and 1 more
MYL2 5 / 49 Arrhythmogenic right ventricular cardiomyopathy, Cardiomyopathy, Dilated cardiomyopathy, Hypertrophic cardiomyopathy and 1 more
MYOM1 5 / 49 Arrhythmogenic right ventricular cardiomyopathy, Cardiac arrest, Cardiomyopathy, Dilated cardiomyopathy and 1 more
RAF1 5 / 49 Cardiac arrhythmia, Cardiomyopathy, Dilated cardiomyopathy, Hypertrophic cardiomyopathy and 1 more
TAFAZZIN 5 / 49 Barth syndrome, Cardiomyopathy, Dilated cardiomyopathy, Left ventricular disease and 1 more
TCAP 5 / 49 Cardiomyopathy, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Left ventricular noncompaction cardiomyopathy and 1 more
TGFB3 5 / 49 Arrhythmogenic right ventricular cardiomyopathy, Arrhythmogenic right ventricular dysplasia, Brugada syndrome, Hypertrophic cardiomyopathy and 1 more
TNNC1 5 / 49 Arrhythmogenic right ventricular cardiomyopathy, Cardiomyopathy, Dilated cardiomyopathy, dilated cardiomyopathy 1Z and 1 more
TNNI3K 5 / 49 Arrhythmogenic right ventricular cardiomyopathy, Atrial tachyarrhythmia, infra-hisian cardiac conduction disease, Bronchial disease, Cardiac conduction disease and 1 more
TRDN 5 / 49 Cardiac arrhythmia, Catecholaminergic polymorphic ventricular tachycardia, Hypertrophic cardiomyopathy, Long qt syndrome and 1 more
ACTA1 4 / 49 Dilated cardiomyopathy, Hypertrophy, Left ventricular disease, Restrictive cardiomyopathy
C2ORF49 4 / 49 Arrhythmogenic right ventricular cardiomyopathy, Cardiomyopathy, Dilated cardiomyopathy, Left ventricular noncompaction cardiomyopathy
CACNA2D1 4 / 49 Brugada syndrome, Cardiac arrest, Long qt syndrome, Ventricular fibrillation
CALM1 4 / 49 Cardiac arrhythmia, Catecholaminergic polymorphic ventricular tachycardia, Long qt syndrome, Polymorphic catecholaminergic ventricular tachycardia
CALM2 4 / 49 Cardiac arrhythmia, Catecholaminergic polymorphic ventricular tachycardia, Long qt syndrome, Polymorphic catecholaminergic ventricular tachycardia
CALR3 4 / 49 Cardiomyopathy, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Restrictive cardiomyopathy
CAV3 4 / 49 Brugada syndrome, Cardiomyopathy, Hypertrophic cardiomyopathy, Long qt syndrome
COL1A1 4 / 49 Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Hypertrophy, Left ventricular disease
CRYAB 4 / 49 Cardiomyopathy, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Myofibrillar myopathy
CSRP3 4 / 49 Cardiomyopathy, Dilated cardiomyopathy, dilated cardiomyopathy 1M, Hypertrophic cardiomyopathy
EDN1 4 / 49 Cardiac arrhythmia, Cardiomyopathy, Hypertrophy, Left ventricular disease
FHL2 4 / 49 Arrhythmogenic right ventricular cardiomyopathy, Cardiomyopathy, Dilated cardiomyopathy, Left ventricular noncompaction cardiomyopathy
FPGT-TNNI3K 4 / 49 Arrhythmogenic right ventricular cardiomyopathy, Bronchial disease, Cardiac conduction disease, Dilated cardiomyopathy
GAA 4 / 49 Cardiomyopathy, Hypertrophic cardiomyopathy, Hypertrophy, Left ventricular disease
GJA5 4 / 49 Atrial flutter, Hereditary atrial fibrillation, Hypertrophic cardiomyopathy, Wolff-parkinson-white syndrome
GPD1L 4 / 49 Brugada syndrome, Dilated cardiomyopathy, Long qt syndrome, Wolff-parkinson-white syndrome
INS 4 / 49 Cardiac arrest, Cardiomyopathy, Hypertrophic cardiomyopathy, Ventricular fibrillation
MAPT 4 / 49 Atrial flutter, Cardiac arrhythmia, Cardiomyopathy, Dilated cardiomyopathy
MYC 4 / 49 Cardiomyopathy, Hypertrophic cardiomyopathy, Hypertrophy, Left ventricular disease
MYLK2 4 / 49 Cardiomyopathy, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Left ventricular noncompaction cardiomyopathy
NPPA 4 / 49 Dilated cardiomyopathy, Hereditary atrial fibrillation, Hypertrophy, Left ventricular disease
OBSCN 4 / 49 Arrhythmogenic right ventricular cardiomyopathy, Cardiomyopathy, Dilated cardiomyopathy, Hypertrophic cardiomyopathy
POMC 4 / 49 Cardiomyopathy, Hypertrophic cardiomyopathy, Long qt syndrome, Sick sinus syndrome
SCN3B 4 / 49 Brugada syndrome, Cardiac arrhythmia, Hereditary atrial fibrillation, Long qt syndrome
SCN4B 4 / 49 Catecholaminergic polymorphic ventricular tachycardia, Dilated cardiomyopathy, Hereditary atrial fibrillation, Long qt syndrome
SLC25A4 4 / 49 Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Left ventricular disease, Restrictive cardiomyopathy
What do these columns mean?
Connections in cluster
How many other members this disease has a shared-gene link to (the node size in the network above). The most-connected diseases are the cluster's core.
Significant partners
How many of those links are statistically significant (FDR q < 0.05).
Curated genes
Distinct curated genes linked to that disease in GeDiPNet.
Member diseases (Top shared genes)
How many of this cluster's diseases are linked to the gene, out of the cluster's total. Genes shared by many members are the most direct explanation of why they group together.
Overlap genes (x / y)
x = genes shared between this cluster and the pathway/GO term; y = that pathway/GO term's total gene count. A higher x relative to y (and to the cluster's own size) means a tighter biological match.
Cluster gene count
Total distinct genes across every disease in this cluster -- the "n" used in the significance test below.
Fold enrichment
Observed overlap divided by the overlap expected by chance, given the cluster's gene count, the pathway/term's size and the gene universe tested. 5× means five times more shared genes than random. Tells strong hits apart when q-values are all vanishingly small.
P-value / FDR q-value
Is this pathway/GO term's overlap with the cluster more than chance? Upper-tail hypergeometric test, Benjamini-Hochberg corrected across every tested pathway/term (prefer the q-value -- it accounts for testing many at once).
Shared genes (Pairs within this cluster)
Number of curated genes the two diseases in that row have in common.
Similarity score (Pairs within this cluster)
Jaccard-based gene overlap between the two specific diseases in that row -- same metric as the main Shared-Gene Disease Pairs page.

Enriched Pathways (why this cluster is grouped, biologically)

Pathway ⇵ Source ⇵ Overlap genes ⇵ Fold enrichment ⇵ P-value ⇵ FDR q-value ⇵
Cytoskeleton in muscle cells
ANKRD1, FLNC, LMNA, PKP2, DES, DSC2, DSG2, DSP, JUP, LDB3, MYBPC3, MYH7
 KEGG 74 / 232 4.8× 9.53e-32 3.09e-28 ✓ sig.
Hypertrophic cardiomyopathy
ACE, AGT, CACNA1C, EDN1, LMNA, RYR2, DES, MYBPC3, MYH7, MYL3, TGFB3, TTN
 KEGG 39 / 99 5.9× 5.61e-21 5.21e-18 ✓ sig.
Dilated cardiomyopathy
AGT, CACNA1C, LMNA, PLN, RYR2, DES, MYBPC3, MYH7, MYL3, TGFB3, TTN, ACTC1
 KEGG 37 / 105 5.3× 4.80e-18 2.80e-15 ✓ sig.
Adrenergic signaling in cardiomyocytes
AGT, CACNA1C, CALM1, CALM2, CALM3, KCNQ1, PLN, PPP1R1A, RYR2, SCN5A, MYH7, MYL3
 KEGG 45 / 154 4.4× 5.17e-18 2.96e-15 ✓ sig.
Proteoglycans in cancer
ANK2, CAV1, CDKN1A, PTK2, WNT8A, CAMK2D, CAV3, PRKCA, SOS1, TNF, CAV2, RAF1
 KEGG 48 / 204 3.5× 5.19e-15 1.74e-12 ✓ sig.
Oxytocin signaling pathway
CACNA1C, CALM1, CALM2, CALM3, KCNJ2, PTGS2, RYR2, CACNB2, RYR1, PRKAG2, CDKN1A, KCNJ5
 KEGG 41 / 154 4.0× 5.76e-15 1.92e-12 ✓ sig.
Striated Muscle Contraction
DES, MYBPC3, MYL3, TTN, ACTC1, ACTN2, DMD, MYH6, MYL2, TNNC1, TNNI3, TNNT2
 Reactome 20 / 36 8.4× 5.78e-15 1.92e-12 ✓ sig.
Arrhythmogenic right ventricular cardiomyopathy
CACNA1C, GJA1, LMNA, PKP2, RYR2, CDH2, CTNNA3, DES, DSC2, DSG2, DSP, JUP
 KEGG 30 / 86 5.3× 9.69e-15 3.04e-12 ✓ sig.
cGMP-PKG signaling pathway
CACNA1C, CALM1, CALM2, CALM3, KNG1, PLN, MYH7, MYH6, GNAI2, GATA4, KCNJ8, INS
 KEGG 42 / 166 3.8× 1.86e-14 5.47e-12 ✓ sig.
Phase 0 - rapid depolarisation
CACNA1C, CALM1, CALM2, CALM3, SCN5A, CACNB2, SCN10A, CACNA2D1, CAMK2D, RANGRF, SCN1B, SCN2B
 Reactome 19 / 44 6.5× 9.72e-12 1.75e-9 ✓ sig.
Calcium signaling pathway
CACNA1C, CALM1, CALM2, CALM3, CASQ2, HTR4, PLN, RYR2, TRDN, RYR1, TNNC1, FGF5
 KEGG 48 / 254 2.8× 2.82e-11 4.57e-9 ✓ sig.
Lipid and atherosclerosis
CALM1, CALM2, CALM3, PTK2, CAMK2D, PRKCA, TNF, AKT1, CYP2C9, FAS, FASLG, HSPD1
 KEGG 43 / 216 3.0× 5.42e-11 8.25e-9 ✓ sig.
Cardiac muscle contraction
CACNA1C, CASQ2, RYR2, TRDN, MYH7, MYL3, ACTC1, CACNB2, MYH6, MYL2, TNNC1, TNNI3
 KEGG 25 / 87 4.3× 2.04e-10 2.74e-8 ✓ sig.
Renin secretion
ACE, AGT, CACNA1C, CALM1, CALM2, CALM3, EDN1, KCNJ2, GNAI2, ADCY5, ADCYAP1, ADRB2
 KEGG 22 / 69 4.8× 2.70e-10 3.53e-8 ✓ sig.
Glioma
CALM1, CALM2, CALM3, CDK6, CDKN1A, CAMK2D, PRKCA, SOS1, RAF1, AKT1, MAPK1, MAPK3
 KEGG 23 / 76 4.6× 3.45e-10 4.40e-8 ✓ sig.

Enriched GO Terms (Biological Process, a second line of biological evidence)

GO term ⇵ GO ID ⇵ Overlap genes ⇵ Fold enrichment ⇵ P-value ⇵ FDR q-value ⇵
regulation of heart rate by cardiac conduction
ACE, CACNA1C, KCNH2, KCNJ2, KCNQ1, PKP2, SCN5A, CTNNA3, DSC2, DSG2, DSP, JUP
 GO:0086091 35 / 43 19.1× 5.66e-41 6.60e-37 ✓ sig.
cardiac muscle contraction
CASQ2, KCNH2, KCNQ1, RYR2, SCN5A, MYBPC3, MYH7, MYL3, TTN, ACTC1, DMD, MYH6
 GO:0060048 35 / 43 19.1× 5.66e-41 6.60e-37 ✓ sig.
sarcomere organization
ANKRD1, FLNC, LDB3, MYBPC3, TTN, ACTN2, MYH6, MYOM1, TNNT2, TPM1, PLEC, PRKAR1A
 GO:0045214 27 / 43 14.7× 9.20e-27 3.39e-23 ✓ sig.
heart development
CACNA1C, EDN1, GJA1, KCNQ1, PKP2, LDB3, TGFB3, ABCC9, MYL2, TNNI3, PRKAR1A, CDKN1A
 GO:0007507 60 / 273 5.2× 2.30e-26 8.22e-23 ✓ sig.
ventricular cardiac muscle cell action potential
KCNH2, KCNQ1, PKP2, RYR2, SCN5A, ANK2, KCNE1, GJA5, CAV3, GPD1L, KCNE3, KCNE5
 GO:0086005 16 / 17 22.1× 1.69e-21 3.31e-18 ✓ sig.
muscle contraction
CACNA1C, TRDN, DES, MYH7, MYL3, TTN, DMD, HCN4, MYH6, RYR1, TACR2, KCND3
 GO:0006936 30 / 85 8.3× 4.17e-20 7.01e-17 ✓ sig.
regulation of ventricular cardiac muscle cell membrane repolarization
KCNH2, KCNQ1, SCN5A, ANK2, KCNE1, GJA5, AKAP9, CACNA2D1, CAV3, KCNE3, KCNE5, SCN1B
 GO:0060307 16 / 21 17.9× 1.73e-18 2.23e-15 ✓ sig.
regulation of heart rate
CALM1, CALM2, CALM3, CASQ2, KCNQ1, RYR2, SCN5A, MYH7, ANK2, DMD, HCN4, MYH6
 GO:0002027 20 / 39 12.0× 1.01e-17 1.17e-14 ✓ sig.
membrane repolarization during ventricular cardiac muscle cell action potential
KCNH2, KCNQ1, KCNE1, KCNJ5, DLG1, KCND3, KCNE3, KCNE5, KCNJ8, SCN2B, KCNE2, KCNJ3
 GO:0098915 12 / 13 21.6× 4.18e-16 3.53e-13 ✓ sig.
regulation of ventricular cardiac muscle cell action potential
CACNA1C, PKP2, RYR2, CTNNA3, DSC2, DSG2, DSP, JUP, TRPM4, CAV1, DLG1
 GO:0098911 11 / 11 23.4× 7.95e-16 6.33e-13 ✓ sig.
cardiac muscle cell action potential involved in contraction
CACNA1C, KCNJ2, PKP2, SCN5A, KCNE1, SCN10A, CACNA2D1, SCN1B, SCN2B, SCN3B, KCNE2, SCN4B
 GO:0086002 15 / 24 14.7× 2.26e-15 1.67e-12 ✓ sig.
vasodilation
ACE, KNG1, ABCC9, GJA5, KCNJ8, INS, TNF, ADORA2A, BDKRB2, NOS3, NPPB, PPARD
 GO:0042311 19 / 50 8.9× 6.58e-14 3.72e-11 ✓ sig.
regulation of cardiac muscle contraction
CALM1, CALM2, CALM3, RYR2, SCN5A, ANK2, HCN4, TNNI3K, GJA5, NKX2-5, SCN10A, CAV3
 GO:0055117 14 / 24 13.7× 7.77e-14 4.36e-11 ✓ sig.
cardiac muscle cell development
TTN, ACTN2, MYH6, PLEC, LRRC10, NKX2-5, CAV3, MYO18B, ALPK3, SGCB, SGCD, TCAP
 GO:0055013 14 / 25 13.1× 1.70e-13 8.98e-11 ✓ sig.
positive regulation of gene expression
AVP, GJA1, LMNA, TTN, ACTC1, ANK2, MYOM1, CAV1, CDK6, MYOCD, NKX2-5, IFNG
 GO:0010628 61 / 504 2.8× 1.76e-13 9.29e-11 ✓ sig.

Pairs within this cluster, by significance

Disease A ⇵ Disease B ⇵ Similarity score ⇵ Shared genes ⇵ P-value ⇵ FDR q-value ⇵
Cardiomyopathy Dilated cardiomyopathy 0.260 107 9.72e-128 1.56e-125 ✓ sig.
Cardiomyopathy Hypertrophic cardiomyopathy 0.253 101 2.63e-120 4.09e-118 ✓ sig.
Dilated cardiomyopathy Hypertrophic cardiomyopathy 0.216 94 3.68e-102 4.60e-100 ✓ sig.
Arrhythmogenic right ventricular cardiomyopathy Dilated cardiomyopathy 0.168 47 1.89e-78 1.56e-76 ✓ sig.
Cardiomyopathy Left ventricular noncompaction cardiomyopathy 0.150 37 5.50e-67 4.03e-65 ✓ sig.
Arrhythmogenic right ventricular cardiomyopathy Cardiomyopathy 0.156 40 6.25e-63 4.22e-61 ✓ sig.
Hypertrophy Left ventricular disease 0.349 30 6.46e-62 4.29e-60 ✓ sig.
Dilated cardiomyopathy Left ventricular noncompaction cardiomyopathy 0.126 35 4.35e-59 2.77e-57 ✓ sig.
Arrhythmogenic right ventricular cardiomyopathy Hypertrophic cardiomyopathy 0.140 38 2.07e-57 1.29e-55 ✓ sig.
Arrhythmogenic right ventricular cardiomyopathy Left ventricular noncompaction cardiomyopathy 0.379 25 8.23e-56 4.97e-54 ✓ sig.
Atrial flutter Cardiac arrhythmia 0.216 32 5.29e-51 2.98e-49 ✓ sig.
Hypertrophic cardiomyopathy Long qt syndrome 0.132 42 2.03e-48 1.08e-46 ✓ sig.
Long qt syndrome Ventricular fibrillation 0.219 25 7.92e-48 4.14e-46 ✓ sig.
Hypertrophic cardiomyopathy Left ventricular noncompaction cardiomyopathy 0.109 29 7.15e-45 3.54e-43 ✓ sig.
Arrhythmogenic right ventricular cardiomyopathy Long qt syndrome 0.202 26 3.05e-44 1.49e-42 ✓ sig.
Dilated cardiomyopathy Long qt syndrome 0.119 40 6.85e-44 3.33e-42 ✓ sig.
Brugada syndrome Long qt syndrome 0.194 27 1.42e-43 6.85e-42 ✓ sig.
Cardiomyopathy Long qt syndrome 0.123 38 1.23e-42 5.78e-41 ✓ sig.
Catecholaminergic polymorphic ventricular tachycardia Long qt syndrome 0.171 18 2.33e-38 9.88e-37 ✓ sig.
Long qt syndrome Wolff-parkinson-white syndrome 0.176 23 9.13e-38 3.79e-36 ✓ sig.
Arrhythmogenic right ventricular cardiomyopathy Wolff-parkinson-white syndrome 0.224 19 1.17e-35 4.57e-34 ✓ sig.
Cardiac arrhythmia Long qt syndrome 0.149 26 1.88e-35 7.28e-34 ✓ sig.
Brugada syndrome Ventricular fibrillation 0.220 18 6.10e-35 2.32e-33 ✓ sig.
Catecholaminergic polymorphic ventricular tachycardia Polymorphic catecholaminergic ventricular tachycardia 0.500 12 1.55e-34 5.81e-33 ✓ sig.
Left ventricular disease Left ventricular noncompaction cardiomyopathy 0.207 18 5.92e-34 2.19e-32 ✓ sig.
Brugada syndrome Wolff-parkinson-white syndrome 0.198 19 9.19e-34 3.36e-32 ✓ sig.
Conduction disorder of the heart Wolff-parkinson-white syndrome 0.246 15 8.30e-33 2.95e-31 ✓ sig.
Ventricular fibrillation Wolff-parkinson-white syndrome 0.222 16 1.06e-31 3.60e-30 ✓ sig.
Arrhythmogenic right ventricular cardiomyopathy Arrhythmogenic right ventricular dysplasia 0.236 13 1.52e-31 5.14e-30 ✓ sig.
Long qt syndrome Polymorphic catecholaminergic ventricular tachycardia 0.135 14 1.85e-30 6.02e-29 ✓ sig.
Arrhythmogenic right ventricular cardiomyopathy Conduction disorder of the heart 0.222 14 7.06e-30 2.26e-28 ✓ sig.
Conduction disorder of the heart Ventricular fibrillation 0.271 13 1.30e-29 4.12e-28 ✓ sig.
Cardiac arrest Ventricular fibrillation 0.260 13 5.40e-29 1.68e-27 ✓ sig.
Left ventricular noncompaction cardiomyopathy Wolff-parkinson-white syndrome 0.200 15 9.52e-29 2.93e-27 ✓ sig.
Arrhythmogenic right ventricular cardiomyopathy Left ventricular disease 0.167 17 1.16e-28 3.55e-27 ✓ sig.
Cardiac arrhythmia Wolff-parkinson-white syndrome 0.136 18 1.33e-27 3.92e-26 ✓ sig.
Brugada syndrome Cardiac arrhythmia 0.133 19 1.44e-27 4.24e-26 ✓ sig.
Arrhythmogenic right ventricular dysplasia Left ventricular noncompaction cardiomyopathy 0.256 11 5.67e-27 1.63e-25 ✓ sig.
Left ventricular disease Wolff-parkinson-white syndrome 0.157 16 1.16e-26 3.31e-25 ✓ sig.
Arrhythmogenic right ventricular cardiomyopathy Restrictive cardiomyopathy 0.188 12 7.36e-25 1.89e-23 ✓ sig.
Arrhythmogenic right ventricular cardiomyopathy Cardiac arrest 0.179 12 5.22e-24 1.28e-22 ✓ sig.
Conduction disorder of the heart Left ventricular noncompaction cardiomyopathy 0.212 11 1.02e-23 2.45e-22 ✓ sig.
Brugada syndrome Conduction disorder of the heart 0.158 12 1.88e-23 4.47e-22 ✓ sig.
Catecholaminergic polymorphic ventricular tachycardia Wolff-parkinson-white syndrome 0.180 11 2.72e-23 6.40e-22 ✓ sig.
Catecholaminergic polymorphic ventricular tachycardia Conduction disorder of the heart 0.250 9 1.63e-21 3.48e-20 ✓ sig.
Left ventricular noncompaction cardiomyopathy Restrictive cardiomyopathy 0.192 10 2.57e-21 5.47e-20 ✓ sig.
Left ventricular disease Restrictive cardiomyopathy 0.139 11 4.85e-21 1.02e-19 ✓ sig.
Brugada syndrome Cardiac arrest 0.139 11 1.58e-20 3.26e-19 ✓ sig.
Arrhythmogenic right ventricular dysplasia Conduction disorder of the heart 0.250 8 6.01e-20 1.21e-18 ✓ sig.
Restrictive cardiomyopathy Wolff-parkinson-white syndrome 0.136 9 1.80e-17 3.18e-16 ✓ sig.
Polymorphic catecholaminergic ventricular tachycardia Wolff-parkinson-white syndrome 0.136 8 5.15e-17 8.88e-16 ✓ sig.
Conduction disorder of the heart Polymorphic catecholaminergic ventricular tachycardia 0.212 7 5.43e-17 9.36e-16 ✓ sig.
Arrhythmogenic right ventricular cardiomyopathy Cardiac conduction disease 0.127 7 1.18e-16 1.99e-15 ✓ sig.
Brugada syndrome Hereditary atrial fibrillation 0.114 9 2.21e-16 3.66e-15 ✓ sig.
Conduction disorder of the heart Restrictive cardiomyopathy 0.171 7 2.05e-15 3.19e-14 ✓ sig.
Cardiac arrest Conduction disorder of the heart 0.159 7 5.50e-15 8.31e-14 ✓ sig.
Atrial flutter Sick sinus syndrome 0.087 8 1.72e-14 2.51e-13 ✓ sig.
Sick sinus syndrome Wolff-parkinson-white syndrome 0.111 7 8.81e-14 1.21e-12 ✓ sig.
Conduction disorder of the heart Hereditary bundle branch system defect 0.185 5 1.24e-13 1.68e-12 ✓ sig.
Cardiac arrest Catecholaminergic polymorphic ventricular tachycardia 0.146 6 4.75e-13 6.26e-12 ✓ sig.
Hereditary bundle branch system defect Ventricular fibrillation 0.128 5 1.09e-12 1.40e-11 ✓ sig.
Arrhythmogenic right ventricular dysplasia Catecholaminergic polymorphic ventricular tachycardia 0.161 5 6.41e-12 7.62e-11 ✓ sig.
Catecholaminergic polymorphic ventricular tachycardia Paroxysmal familial ventricular fibrillation 0.182 4 1.03e-11 1.20e-10 ✓ sig.
Hereditary atrial fibrillation Ventricular fibrillation 0.109 6 1.38e-11 1.59e-10 ✓ sig.
Cardiac arrest Paroxysmal familial ventricular fibrillation 0.143 4 3.19e-11 3.53e-10 ✓ sig.
Catecholaminergic polymorphic ventricular tachycardia Hereditary bundle branch system defect 0.167 4 7.22e-11 7.72e-10 ✓ sig.
Atrial flutter Wolff-parkinson-white syndrome 0.064 8 2.18e-10 2.24e-9 ✓ sig.
Cardiac conduction disease Conduction disorder of the heart 0.133 4 5.69e-10 5.58e-9 ✓ sig.
Arrhythmogenic right ventricular dysplasia Polymorphic catecholaminergic ventricular tachycardia 0.148 4 7.91e-10 7.64e-9 ✓ sig.
Atrioventricular block Sick sinus syndrome 0.125 4 3.08e-9 2.81e-8 ✓ sig.
Cardiac conduction disease Hereditary bundle branch system defect 0.214 3 4.83e-9 4.31e-8 ✓ sig.
Arrhythmogenic right ventricular dysplasia Paroxysmal familial ventricular fibrillation 0.167 3 7.47e-9 6.56e-8 ✓ sig.
Hereditary atrial fibrillation Sick sinus syndrome 0.103 4 1.37e-8 1.15e-7 ✓ sig.
Conduction disorder of the heart Sick sinus syndrome 0.103 4 1.37e-8 1.15e-7 ✓ sig.
Cardiac conduction disease Sick sinus syndrome 0.120 3 1.12e-7 8.25e-7 ✓ sig.
Hereditary atrial fibrillation Hereditary bundle branch system defect 0.103 3 1.16e-7 8.52e-7 ✓ sig.
Hereditary bundle branch system defect Paroxysmal familial ventricular fibrillation 0.182 2 1.77e-6 1.05e-5 ✓ sig.
Cardiac conduction disease Paroxysmal familial ventricular fibrillation 0.154 2 3.03e-6 1.72e-5 ✓ sig.
Atrioventricular block Hereditary bundle branch system defect 0.087 2 2.40e-5 1.19e-4 ✓ sig.
Atrioventricular block Cardiac conduction disease 0.080 2 4.11e-5 1.98e-4 ✓ sig.
Bronchial disease Cardiac conduction disease 0.077 2 4.62e-5 2.22e-4 ✓ sig.
Arrhythmogenic right ventricular dysplasia Myofibrillar myopathy 0.077 2 5.81e-5 2.34e-4 ✓ sig.
Atrial tachyarrhythmia, infra-hisian cardiac conduction disease Cardiac conduction disease 0.100 1 5.84e-4 1.14e-3 ✓ sig.
dilated cardiomyopathy 1HH Myofibrillar myopathy 0.077 1 7.79e-4 1.39e-3 ✓ sig.
dilated cardiomyopathy 1I Myofibrillar myopathy 0.077 1 7.79e-4 1.39e-3 ✓ sig.
Myofibrillar myopathy myofibrillar myopathy 8 0.077 1 7.79e-4 1.39e-3 ✓ sig.
Arrhythmogenic right ventricular dysplasia dilated cardiomyopathy 1BB 0.063 1 9.74e-4 1.64e-3 ✓ sig.
Arrhythmogenic right ventricular dysplasia dilated cardiomyopathy 1HH 0.063 1 9.74e-4 1.64e-3 ✓ sig.
Arrhythmogenic right ventricular dysplasia familial isolated arrhythmogenic right ventricular dysplasia 0.063 1 9.74e-4 1.64e-3 ✓ sig.
Atrioventricular block dilated cardiomyopathy 1HH 0.056 1 1.10e-3 1.81e-3 ✓ sig.
Atrioventricular block dilated cardiomyopathy 1I 0.056 1 1.10e-3 1.81e-3 ✓ sig.
Atrial tachyarrhythmia, infra-hisian cardiac conduction disease Bronchial disease 0.053 1 1.17e-3 1.88e-3 ✓ sig.
Bronchial disease Vici syndrome 0.053 1 1.17e-3 1.88e-3 ✓ sig.
Sick sinus syndrome sick sinus syndrome 2, autosomal dominant 0.053 1 1.17e-3 1.88e-3 ✓ sig.
Catecholaminergic polymorphic ventricular tachycardia dilated cardiomyopathy 1BB 0.048 1 1.30e-3 2.04e-3 ✓ sig.
Catecholaminergic polymorphic ventricular tachycardia dilated cardiomyopathy 1JJ 0.048 1 1.30e-3 2.04e-3 ✓ sig.
dilated cardiomyopathy 1I Restrictive cardiomyopathy 0.042 1 1.49e-3 2.29e-3 ✓ sig.
Conduction disorder of the heart dilated cardiomyopathy 1BB 0.040 1 1.56e-3 2.36e-3 ✓ sig.
Cardiac arrest dilated cardiomyopathy 1BB 0.037 1 1.69e-3 2.51e-3 ✓ sig.
Cardiac arrest intrinsic cardiomyopathy 0.037 1 1.69e-3 2.51e-3 ✓ sig.
Cardiac arrest lissencephaly 10 0.037 1 1.69e-3 2.51e-3 ✓ sig.
Cardiac arrest sick sinus syndrome 2, autosomal dominant 0.037 1 1.69e-3 2.51e-3 ✓ sig.
cardiomyopathy, dilated, 2e Ventricular fibrillation 0.027 1 2.34e-3 3.23e-3 ✓ sig.
Congenital right-sided heart lesions Ventricular fibrillation 0.027 1 2.34e-3 3.23e-3 ✓ sig.
dilated cardiomyopathy 1BB Ventricular fibrillation 0.027 1 2.34e-3 3.23e-3 ✓ sig.
Barth syndrome Left ventricular noncompaction cardiomyopathy 0.026 1 2.47e-3 3.36e-3 ✓ sig.
cardiomyopathy, dilated, 2e Left ventricular noncompaction cardiomyopathy 0.026 1 2.47e-3 3.36e-3 ✓ sig.
dilated cardiomyopathy 1CC Left ventricular noncompaction cardiomyopathy 0.026 1 2.47e-3 3.36e-3 ✓ sig.
dilated cardiomyopathy 1JJ Left ventricular noncompaction cardiomyopathy 0.026 1 2.47e-3 3.36e-3 ✓ sig.
dilated cardiomyopathy 1Y Left ventricular noncompaction cardiomyopathy 0.026 1 2.47e-3 3.36e-3 ✓ sig.
Left ventricular noncompaction cardiomyopathy sick sinus syndrome 2, autosomal dominant 0.026 1 2.47e-3 3.36e-3 ✓ sig.
dilated cardiomyopathy 1JJ Wolff-parkinson-white syndrome 0.019 1 3.31e-3 4.30e-3 ✓ sig.
FNIP1-associated syndrome Wolff-parkinson-white syndrome 0.019 1 3.31e-3 4.30e-3 ✓ sig.
Arrhythmogenic right ventricular cardiomyopathy Atrial tachyarrhythmia, infra-hisian cardiac conduction disease 0.019 1 3.38e-3 4.37e-3 ✓ sig.
Arrhythmogenic right ventricular cardiomyopathy dilated cardiomyopathy 1CC 0.019 1 3.38e-3 4.37e-3 ✓ sig.
Arrhythmogenic right ventricular cardiomyopathy dilated cardiomyopathy 1JJ 0.019 1 3.38e-3 4.37e-3 ✓ sig.
Arrhythmogenic right ventricular cardiomyopathy dilated cardiomyopathy 1Y 0.019 1 3.38e-3 4.37e-3 ✓ sig.
Arrhythmogenic right ventricular cardiomyopathy dilated cardiomyopathy 1Z 0.019 1 3.38e-3 4.37e-3 ✓ sig.
Arrhythmogenic right ventricular cardiomyopathy familial isolated arrhythmogenic right ventricular dysplasia 0.019 1 3.38e-3 4.37e-3 ✓ sig.
Arrhythmogenic right ventricular cardiomyopathy intrinsic cardiomyopathy 0.019 1 3.38e-3 4.37e-3 ✓ sig.
Arrhythmogenic right ventricular cardiomyopathy lissencephaly 10 0.019 1 3.38e-3 4.37e-3 ✓ sig.
Brugada syndrome dilated cardiomyopathy 1JJ 0.016 1 4.09e-3 5.16e-3 ✓ sig.
Brugada syndrome hypokalemic alkalosis, familial, with specific renal tubulopathy 0.016 1 4.09e-3 5.16e-3 ✓ sig.
Barth syndrome Left ventricular disease 0.015 1 4.29e-3 5.38e-3 ✓ sig.
cardiomyopathy, dilated, 2e Left ventricular disease 0.015 1 4.29e-3 5.38e-3 ✓ sig.
dilated cardiomyopathy 1CC Left ventricular disease 0.015 1 4.29e-3 5.38e-3 ✓ sig.
dilated cardiomyopathy 1Y Left ventricular disease 0.015 1 4.29e-3 5.38e-3 ✓ sig.
familial isolated arrhythmogenic right ventricular dysplasia Left ventricular disease 0.015 1 4.29e-3 5.38e-3 ✓ sig.
5-oxoprolinase deficiency Atrial flutter 0.012 1 5.26e-3 6.42e-3 ✓ sig.
Cardiac arrhythmia intrinsic cardiomyopathy 0.010 1 6.36e-3 7.64e-3 ✓ sig.
dilated cardiomyopathy 1CC Long qt syndrome 0.010 1 6.62e-3 7.89e-3 ✓ sig.
familial isolated arrhythmogenic right ventricular dysplasia Long qt syndrome 0.010 1 6.62e-3 7.89e-3 ✓ sig.
Barth syndrome Cardiomyopathy 0.004 1 1.58e-2 1.75e-2 ✓ sig.
Cardiomyopathy dilated cardiomyopathy 1CC 0.004 1 1.58e-2 1.75e-2 ✓ sig.
Cardiomyopathy dilated cardiomyopathy 1M 0.004 1 1.58e-2 1.75e-2 ✓ sig.
Cardiomyopathy dilated cardiomyopathy 1Z 0.004 1 1.58e-2 1.75e-2 ✓ sig.
Cardiomyopathy intrinsic cardiomyopathy 0.004 1 1.58e-2 1.75e-2 ✓ sig.
Cardiomyopathy Vici syndrome 0.004 1 1.58e-2 1.75e-2 ✓ sig.
dilated cardiomyopathy 1M Hypertrophic cardiomyopathy 0.004 1 1.66e-2 1.83e-2 ✓ sig.
dilated cardiomyopathy 1Z Hypertrophic cardiomyopathy 0.004 1 1.66e-2 1.83e-2 ✓ sig.
Atrial tachyarrhythmia, infra-hisian cardiac conduction disease Dilated cardiomyopathy 0.004 1 1.77e-2 1.94e-2 ✓ sig.
Barth syndrome Dilated cardiomyopathy 0.004 1 1.77e-2 1.94e-2 ✓ sig.
cardiomyopathy, dilated, 2h Dilated cardiomyopathy 0.004 1 1.77e-2 1.94e-2 ✓ sig.
Dilated cardiomyopathy dilated cardiomyopathy 1M 0.004 1 1.77e-2 1.94e-2 ✓ sig.
Dilated cardiomyopathy dilated cardiomyopathy 1Z 0.004 1 1.77e-2 1.94e-2 ✓ sig.