Introduction

GeDiPNet (Gene Disease Pathway Network) is a comprehensive database on all human gene disease pathway networks. The database integrates gene-disease relationships from major authoritative sources including DisGeNET, ClinGen, ClinVar, GenCC, GWAS Catalog, CBGDA (CRISPR-Based Gene-Disease Associations), the Human Phenotype Ontology (HPO), OrphaNet, PsyGeNET, CTD, and textmining. Information in the database is compiled and maintained through manual curation to ensure standardized disease terminology and reduce redundancy. GeDiPNet defines gene-disease associations based on both literature-curated evidence and text-mining approaches. The database provides comprehensive information on genes, single nucleotide polymorphisms (SNPs), diseases, and biological pathways, with detailed annotations including gene synonyms, chromosomal locations, expression profiles, and protein-related data.

GeDiPNet is an open source resource that is developed and maintained by the Biomedical Informatics Centre at the ICMR – National Institute for Research on Women's Health (ICMR-NIRWoH), formerly ICMR-NIRRCH, located at Mumbai, India.