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Guide
Help
Step-by-step user manual: search, browse genes & diseases, pathway analysis, enrichment, comorbidity, and more.
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Data
Versions
Compare the live Version 2 dataset against the frozen Version 1 snapshot — what's in each, and when to use which.
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Community
Community
Partner databases, cross-referenced resources, and data sources integrated into GeDiPNet.
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Support
FAQ
Answers to common questions about data curation, sources, scoring, and platform usage.
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Developer
API
Technical guide to integrating GeDiPNet gene-disease data into your own research pipelines.
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Reference
Glossary
Plain-language definitions for every analysis term GeDiPNet uses — p-value, weighted degree, comorbidity score, and more.
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Introduction to GeDiPNet How to search genes & diseases Browse genes A–Z Browse diseases Enrichment analysis Comorbidity analysis Polypharmacological targets Venn analysis Glossary of terms Dataset versions (v1 vs v2) Cite GeDiPNet in your paper Partner databases Frequently Asked Questions Contact & support

Cross-Referenced Resources

Data Sources

GeDiPNet integrates data from 11 authoritative bioinformatics resource categories. Click any category to expand.

11 categories 38 sources
Gene 5 Disease 9 Pathway 2 Protein 3 SNP 1 Gene Ontology 1 miRNA 1 Transcription Factor 1 Drug 2 Drug Deep-Dive 10 Literature 3
NCBI Gene
Integrates nomenclature, RefSeqs, maps, pathways, variations, and phenotypes across species.
Human Protein Atlas
Expression profiles of human genes at the mRNA and protein level across tissues.
MIM
Comprehensive catalog of Mendelian traits, disorders, human genes, and genetic phenotypes.
HGNC
HUGO Gene Nomenclature Committee — standardized names and symbols for all human genes.
Ensembl
Genome browser for vertebrate genomes supporting comparative genomics and transcriptional regulation.
DisGeNET
Comprehensive platform for human gene-disease and variant-disease associations.
ClinVar
Public archive of human genetic variations and associated phenotypes with supporting evidence.
Human Phenotype Ontology
Standardized vocabulary of phenotypic abnormalities encountered in human disease.
OMIM
Authoritative compendium of human genes and genetic phenotypes.
Orphanet
Global knowledge base for rare diseases and orphan drugs with expert-validated information.
ClinGen
NIH-funded resource defining clinical relevance of genes and variants for precision medicine.
GWAS Catalog
EMBL-EBI's catalog of published genome-wide association studies, linking SNPs to disease and trait associations.
GenCC
Gene Curation Coalition — harmonized gene-disease validity classifications from multiple clinical curation groups.
PsyGeNET
Knowledge platform for exploratory analysis of psychiatric diseases and their associated genes.
KEGG
Kyoto Encyclopedia of Genes and Genomes — linking genomic information with higher-order functional information.
Reactome
Free, open-source, peer-reviewed database of human biological pathways and processes.
UniProt
Comprehensive global resource for protein sequence and functional information.
STRING
Database of known and predicted protein-protein interactions.
Pfam
Large collection of protein families represented by multiple sequence alignments and HMMs (now hosted within InterPro).
dbSNP
Repository of human single nucleotide variations, microsatellites, and small-scale insertions/deletions.
Gene Ontology
Structured, controlled vocabularies for annotating genes and gene products in molecular and cellular biology.
miRTarBase
Comprehensive, experimentally validated database of microRNA-target interactions.
TRRUST v2
Manually curated database of human and mouse transcriptional regulatory networks.
DGIdb
Drug-Gene Interaction Database — aggregating drug and gene data for druggable therapeutic target discovery.
CTD
Comparative Toxicogenomics Database — curated chemical-gene interaction data. Used under CTD's terms of use; see ctdbase.org/about/legal.jsp.
ClinicalTrials.gov
U.S. National Library of Medicine registry of clinical trials worldwide — checks whether a predicted drug is already approved, in trial, or untested for a given disease.
GTEx Portal
Genotype-Tissue Expression project — reference gene expression levels across human tissues, used to verify a predicted target gene is actually expressed where it matters.
Expression Atlas
EMBL-EBI's gene expression database across conditions and diseases — surfaces relevant transcriptomic studies for a disease.
cBioPortal
Cancer genomics portal providing TCGA (The Cancer Genome Atlas) expression data, used for cancer-specific transcriptomic cross-referencing.
SIDER
Side Effect Resource — known, on-label side effects listed on official drug labels.
OFFSIDES (nSIDES)
Statistically significant off-label side effect signals mined from FDA adverse event reports, not listed on the official drug label.
ADMETlab 3.0
Predicts Absorption, Distribution, Metabolism, Excretion, and Toxicity (ADMET) properties, including blood-brain barrier penetration and drug-likeness, from a drug's chemical structure.
ChEMBL
EMBL-EBI's manually curated database of bioactive drug-like molecules, used to resolve a drug's chemical structure (SMILES).
PubChem
NIH's open chemistry database, used as a fallback to resolve a drug's chemical structure by name when ChEMBL doesn't have it.
NCI Chemical Identifier Resolver (CIR)
NCI's name-to-structure lookup service, used as a final fallback to resolve a drug's chemical structure when neither ChEMBL nor PubChem recognizes the name.
PubMed
Database of biomedical and life science literature maintained by NCBI.
MeSH
Controlled, hierarchical vocabulary from NLM for indexing and searching biomedical information.
Medline
NLM's premier bibliographic database with references to life sciences journal articles.

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