The GeDiPNet Community serves as a collaborative platform uniting researchers, clinicians, and bioinformaticians committed to advancing the understanding of gene-disease associations. By contributing high-quality, evidence-based data, members play a vital role in expanding the global landscape of both diverse and rare gene-disease associations.
GeDiPNet has been integrated into several leading bioinformatics platforms, enabling seamless access to gene-disease-pathway networks:
A comprehensive gene set enrichment analysis tool that allows users to submit lists of genes and compare them against hundreds of annotated gene set libraries, such as biological pathways, diseases, transcription factors, and more.
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Metascape is a gene annotation and analysis resource that integrates numerous bioinformatics databases to provide biologists with streamlined, interpretable, and comprehensive OMICs data analysis through a user-friendly web interface.
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Submit Your Data Join Our CommunityGeDiPNet integrates and cross-references data from authoritative bioinformatics resources to ensure comprehensive and accurate gene-disease-pathway associations:
| NCBI Gene | NCBI Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome, phenotype and locus-specific resources worldwide. |
| The Human Protein Atlas | This resource focuses on the expression profiles in human tissues of genes both on the mRNA and protein level. |
| MIM | MIM (Mendelian Inheritance in Man) is a comprehensive catalog of mendelian traits and disorders, human genes, and genetic phenotypes. |
| HGNC | HUGO Gene Nomenclature Committee provides unique and standardized names and symbols for all known human genes. |
| Ensembl | A genome browser for vertebrate genomes that supports research in comparative genomics, evolution, sequence variation and transcriptional regulation. |
| DisGeNet | A free, comprehensive knowledge platform for human gene-disease and variant-disease associations. |
| ClinVar | A public archive that collects and freely provides information on human genetic variations, their associated phenotypes, and supporting evidence. |
| Human Phenotype Ontology | Provides a standardized vocabulary of phenotypic abnormalities encountered in human disease. |
| OMIM | A comprehensive, authoritative, and freely available compendium of human genes and genetic phenotypes. |
| Orphanet | A comprehensive and freely accessible global knowledge base dedicated to providing expert-validated information on rare diseases and orphan drugs. |
| ClinGen | An NIH-funded resource that defines the clinical relevance of genes and variants for use in precision medicine and research. |
| PsyGeNET | A knowledge platform for the exploratory analysis of psychiatric diseases and their associated genes. |
| KEGG | Kyoto Encyclopedia of Genes and Genomes - a knowledge base for systematic analysis of gene functions, linking genomic information with higher order functional information. |
| Reactome | A free, open-source, and peer-reviewed online database of human biological pathways and processes. |
| UniProt | A comprehensive, high-quality, and freely accessible global resource for protein sequence and functional information. |
| STRING | A database of known and predicted protein-protein interactions. |
| Pfam | A large collection of protein families represented by multiple sequence alignments and hidden Markov models. |
| dbSNP | Contains human single nucleotide variations, microsatellites, and small-scale insertions and deletions. |
| Gene Ontology | The Gene Ontology (GO) project provides free, structured, controlled vocabularies for annotating genes, gene products, and sequences in molecular and cellular biology. |
| miRTarBase | miRTarBase is a comprehensive, experimentally validated database that focuses on microRNA-target interactions (MTIs). |
| TRRUST v2 | A manually curated database of human and mouse transcriptional regulatory networks. |
| DGIdb | Drug-Gene Interaction Database (DGIdb) streamlines the search for druggable therapeutic targets through the aggregation, categorization, and curation of drug and gene data from publications and expert resources. |
| PubMed | Database of biomedical and life science literature maintained by NCBI. |
| MeSH | MeSH (Medical Subject Headings) is a controlled, hierarchical vocabulary from the National Library of Medicine, used for indexing and searching biomedical information in databases like MEDLINE/PubMed. |
| Medline | MEDLINE is the National Library of Medicine's (NLM) premier bibliographic database that contains references to journal articles in life sciences, with a concentration on biomedicine. |