Frequently Asked Questionsⓘ

GeDiPNet (Gene Disease Pathway Network) is an open-access database that integrates gene-disease associations from various sources, offering curated information on human genes, diseases, SNPs, and pathways. It supports efficient analysis of gene-disease relationships and is designed for high-throughput analysis to identify insights into genetic disease associations, polypharmacological targets, and gene-disease pathway networks. GeDiPNet is a comprehensive resource for exploring gene-disease interactions, helping researchers uncover novel insights in genetic disease research and precision medicine.

Studying gene-disease associations helps understand disease mechanisms, identify diagnostic biomarkers, inform personalized medicine, and enable risk assessment and predictive medicine.

GeDiPNet provides comprehensive information on human genes, including gene-disease associations, protein domain/family data, pathway analysis, functional annotations, gene expression, regulation, genetic variations, and protein-protein interactions.

GeDiPNet provides four types of analysis: enrichment analysis for identifying significant gene-disease associations, comorbidity prediction for exploring disease relationships, Venn analysis for examining overlaps in genes or pathways, and polypharmacological target prediction for assessing potential multi-target therapeutics.

Sub-types or similar disease names are merged into unique terms for efficient analysis.

GeDiPNet is regularly updated to ensure the latest research and data are included.

Contact our support team at biomedinfo@nirrch.res.in

Kundu I, Sharma M, Barai RS, Pokar K, Idicula-Thomas S (2023). GeDiPNet: Online resource of curated gene-disease associations for polypharmacological targets discovery. Genes & Diseases, https://doi.org/10.1016/j.gendis.2022.05.034