Disease Clusters?

Groups of diseases that share a large number of curated genes with each other, computed via label propagation over the shared-gene similarity graph. See also Shared-Gene Disease Pairs for pairwise comparisons.

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Cluster 6

57 diseases · 198 shared-gene connections
57 Diseases
650 Unique genes
0.053 Avg. similarity score
Isolated sensorineural deafness Most-connected disease (43 links)
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Disease Searched: Hearing loss, autosomal recessive 115 Pinned (dragged)
Node size = connections within this cluster · edge thickness = similarity strength · hover an edge for its details · click a node to select it and show its pairs below (double-click or Ctrl/⌘-click opens the disease page) · drag a node to pin it in place · scroll/pinch to zoom.
Hearing loss, autosomal recessive 115 Isolated sensorineural deafness Nonsyndromic genetic hearing loss Nonsyndromic hearing loss Deafness Hearing loss

Member diseases (most connected first ‐ the cluster's core)

Disease ⇵ Connections in cluster ⇵ Significant partners ⇵ Curated genes ⇵
Isolated sensorineural deafness 43 43 119
Nonsyndromic genetic hearing loss 40 40 82
Nonsyndromic hearing loss 40 40 119
Deafness 30 30 177
Hearing loss 17 17 397
Hereditary hearing loss 17 17 50
Nonsyndromic intellectual disability 12 12 142
Congenital ear anomaly 11 11 31
Meniere disease 7 7 68
Usher syndrome 7 7 44
Auditory neuropathy 5 5 31
Autosomal dominant nonsyndromic hearing loss 5 5 12
Deafness, autosomal dominant 21 5 5 1
Deafness, autosomal dominant 25 5 5 1
Deafness, autosomal dominant 2a 5 5 1
Deafness, autosomal dominant 44 5 5 1
Deafness, autosomal recessive 106 5 5 1
Deafness, autosomal recessive 117 5 5 1
Deafness, autosomal recessive 15 5 5 1
Deafness, autosomal recessive 18b 5 5 1
Deafness, autosomal recessive 22 5 5 1
Deafness, autosomal recessive 25 5 5 1
Deafness, autosomal recessive 35 5 5 1
Deafness, autosomal recessive 49 5 5 1
Deafness, autosomal recessive 61 5 5 1
Deafness, autosomal recessive 67 5 5 1
Deafness, autosomal recessive 76 5 5 1
Deafness, autosomal recessive 79 5 5 1
Deafness, autosomal recessive 93 5 5 1
Deafness, autosomal dominant 40 4 4 1
Deafness, autosomal dominant 41 4 4 1
Deafness, autosomal dominant 68 4 4 1
Deafness, autosomal dominant, 70 4 4 1
Deafness, autosomal recessive 108 4 4 1
Deafness, autosomal recessive 111 4 4 1
Deafness, autosomal recessive 68 4 4 1
Deafness, autosomal recessive 77 4 4 1
Deafness, autosomal recessive 91 4 4 1
Hearing loss, autosomal recessive 120 4 4 1
Worster drought syndrome 4 4 1
Auditory neuropathy, autosomal dominant, 1 3 3 1
Deafness, autosomal dominant 64 3 3 1
Deafness, autosomal recessive 103 3 3 1
Deafness, autosomal recessive 109 3 3 1
Deafness, autosomal recessive 74 3 3 1
Pancreas adenocarcinoma 3 3 1
Deafness, autosomal dominant, 77 2 2 1
Deafness, autosomal dominant, 79 2 2 1
Hearing loss, autosomal recessive 115 2 2 1
Retinitis pigmentosa-deafness syndrome 2 2 11
Al-raqad syndrome 1 1 1
Deafness, autosomal dominant 50 1 1 1
Deafness, autosomal dominant 7 1 1 1
Mental retardation, autosomal recessive 56 1 1 1
Neurodevelopmental disorder with cerebral atrophy and variable facial dysmorphism 1 1 1
Neurodevelopmental disorder with hypotonia and gross motor and speech delay 1 1 1
Otofacial neurodevelopmental syndrome 1 1 1

Top shared genes (genes linked to 2+ member diseases ‐ top 100 shown, download for all)

Gene ⇵ Member diseases ⇵ Linked diseases
MYO7A 11 / 57 Auditory neuropathy, Congenital ear anomaly, Deafness, Hearing loss and 7 more
CDH23 10 / 57 Congenital ear anomaly, Deafness, Hearing loss, Hereditary hearing loss and 6 more
PCDH15 10 / 57 Congenital ear anomaly, Deafness, Hearing loss, Hereditary hearing loss and 6 more
LHFPL5 9 / 57 Congenital ear anomaly, Deafness, Deafness, autosomal recessive 67, Hearing loss and 5 more
OTOF 9 / 57 Auditory neuropathy, Congenital ear anomaly, Deafness, Hearing loss and 5 more
WFS1 9 / 57 Auditory neuropathy, Autosomal dominant nonsyndromic hearing loss, Deafness, Hearing loss and 5 more
LOXHD1 8 / 57 Deafness, Deafness, autosomal recessive 77, Hearing loss, Hereditary hearing loss and 4 more
MARVELD2 8 / 57 Congenital ear anomaly, Deafness, Deafness, autosomal recessive 49, Hearing loss and 4 more
MYO6 8 / 57 Congenital ear anomaly, Deafness, Hearing loss, Hereditary hearing loss and 4 more
OTOA 8 / 57 Deafness, Deafness, autosomal recessive 22, Hearing loss, Hereditary hearing loss and 4 more
SERPINB6 8 / 57 Deafness, Deafness, autosomal recessive 91, Hearing loss, Isolated sensorineural deafness and 4 more
SLC17A8 8 / 57 Auditory neuropathy, Deafness, Deafness, autosomal dominant 25, Hearing loss and 4 more
TECTA 8 / 57 Congenital ear anomaly, Deafness, Hearing loss, Hereditary hearing loss and 4 more
TMC1 8 / 57 Congenital ear anomaly, Deafness, Hearing loss, Hereditary hearing loss and 4 more
TMPRSS3 8 / 57 Congenital ear anomaly, Deafness, Hearing loss, Hereditary hearing loss and 4 more
TPRN 8 / 57 Congenital ear anomaly, Deafness, Deafness, autosomal recessive 79, Hearing loss and 4 more
USH1C 8 / 57 Deafness, Hearing loss, Hereditary hearing loss, Isolated sensorineural deafness and 4 more
WHRN 8 / 57 Deafness, Hearing loss, Hereditary hearing loss, Isolated sensorineural deafness and 4 more
ACTG1 7 / 57 Autosomal dominant nonsyndromic hearing loss, Deafness, Hearing loss, Hereditary hearing loss and 3 more
CABP2 7 / 57 Deafness, Deafness, autosomal recessive 93, Hearing loss, Isolated sensorineural deafness and 3 more
CCDC50 7 / 57 Deafness, Deafness, autosomal dominant 44, Hearing loss, Hereditary hearing loss and 3 more
COCH 7 / 57 Deafness, Hearing loss, Hereditary hearing loss, Isolated sensorineural deafness and 3 more
COL11A2 7 / 57 Congenital ear anomaly, Deafness, Hearing loss, Hereditary hearing loss and 3 more
ESPN 7 / 57 Deafness, Hearing loss, Hereditary hearing loss, Isolated sensorineural deafness and 3 more
ESRRB 7 / 57 Deafness, Deafness, autosomal recessive 35, Hearing loss, Hereditary hearing loss and 3 more
GJB2 7 / 57 Congenital ear anomaly, Deafness, Hearing loss, Hereditary hearing loss and 3 more
KCNQ4 7 / 57 Deafness, Deafness, autosomal dominant 2a, Hearing loss, Hereditary hearing loss and 3 more
MSRB3 7 / 57 Deafness, Deafness, autosomal recessive 74, Hearing loss, Isolated sensorineural deafness and 3 more
MYH14 7 / 57 Deafness, Hearing loss, Hereditary hearing loss, Isolated sensorineural deafness and 3 more
MYO15A 7 / 57 Congenital ear anomaly, Deafness, Hearing loss, Hereditary hearing loss and 3 more
OTOG 7 / 57 Deafness, Deafness, autosomal recessive 18b, Hearing loss, Isolated sensorineural deafness and 3 more
OTOGL 7 / 57 Deafness, Hearing loss, Isolated sensorineural deafness, Meniere disease and 3 more
PJVK 7 / 57 Congenital ear anomaly, Deafness, Hearing loss, Hereditary hearing loss and 3 more
RIPOR2 7 / 57 Autosomal dominant nonsyndromic hearing loss, Deafness, Deafness, autosomal dominant 21, Hearing loss and 3 more
S1PR2 7 / 57 Deafness, Deafness, autosomal recessive 68, Hearing loss, Isolated sensorineural deafness and 3 more
SLC26A5 7 / 57 Deafness, Deafness, autosomal recessive 61, Hearing loss, Isolated sensorineural deafness and 3 more
SYNE4 7 / 57 Deafness, Deafness, autosomal recessive 76, Hearing loss, Isolated sensorineural deafness and 3 more
TBC1D24 7 / 57 Auditory neuropathy, Deafness, Hearing loss, Isolated sensorineural deafness and 3 more
TMIE 7 / 57 Congenital ear anomaly, Deafness, Hearing loss, Hereditary hearing loss and 3 more
ABCC1 6 / 57 Autosomal dominant nonsyndromic hearing loss, Deafness, Deafness, autosomal dominant, 77, Hearing loss and 2 more
ATP11A 6 / 57 Auditory neuropathy, Autosomal dominant nonsyndromic hearing loss, Deafness, Hearing loss and 2 more
C10ORF105 6 / 57 Congenital ear anomaly, Deafness, Hearing loss, Meniere disease and 2 more
CDC14A 6 / 57 Congenital ear anomaly, Deafness, Hearing loss, Isolated sensorineural deafness and 2 more
CEACAM16 6 / 57 Congenital ear anomaly, Deafness, Hearing loss, Isolated sensorineural deafness and 2 more
CIB2 6 / 57 Deafness, Hearing loss, Isolated sensorineural deafness, Nonsyndromic genetic hearing loss and 2 more
CLDN14 6 / 57 Deafness, Hearing loss, Hereditary hearing loss, Isolated sensorineural deafness and 2 more
CLRN2 6 / 57 Deafness, Deafness, autosomal recessive 117, Hearing loss, Isolated sensorineural deafness and 2 more
COL11A1 6 / 57 Autosomal dominant nonsyndromic hearing loss, Deafness, Hearing loss, Isolated sensorineural deafness and 2 more
DCDC2 6 / 57 Deafness, Hearing loss, Isolated sensorineural deafness, Nonsyndromic genetic hearing loss and 2 more
DIABLO 6 / 57 Deafness, Deafness, autosomal dominant 64, Hearing loss, Isolated sensorineural deafness and 2 more
ELMOD3 6 / 57 Deafness, Hearing loss, Isolated sensorineural deafness, Nonsyndromic genetic hearing loss and 2 more
EPS8L2 6 / 57 Deafness, Deafness, autosomal recessive 106, Hearing loss, Isolated sensorineural deafness and 2 more
EYA4 6 / 57 Deafness, Hearing loss, Hereditary hearing loss, Isolated sensorineural deafness and 2 more
GIPC3 6 / 57 Deafness, Deafness, autosomal recessive 15, Hearing loss, Isolated sensorineural deafness and 2 more
GRHL2 6 / 57 Deafness, Hearing loss, Hereditary hearing loss, Isolated sensorineural deafness and 2 more
GRXCR1 6 / 57 Deafness, Deafness, autosomal recessive 25, Hearing loss, Isolated sensorineural deafness and 2 more
GSDME 6 / 57 Deafness, Hearing loss, Hereditary hearing loss, Isolated sensorineural deafness and 2 more
HGF 6 / 57 Deafness, Hearing loss, Hereditary hearing loss, Isolated sensorineural deafness and 2 more
KARS1 6 / 57 Deafness, Hearing loss, Isolated sensorineural deafness, Nonsyndromic genetic hearing loss and 2 more
LMX1A 6 / 57 Autosomal dominant nonsyndromic hearing loss, Deafness, Deafness, autosomal dominant 7, Hearing loss and 2 more
LRTOMT 6 / 57 Deafness, Hearing loss, Hereditary hearing loss, Isolated sensorineural deafness and 2 more
MET 6 / 57 Deafness, Hearing loss, Isolated sensorineural deafness, Nonsyndromic genetic hearing loss and 2 more
MYH9 6 / 57 Deafness, Hearing loss, Hereditary hearing loss, Isolated sensorineural deafness and 2 more
MYO3A 6 / 57 Deafness, Hearing loss, Hereditary hearing loss, Isolated sensorineural deafness and 2 more
POU4F3 6 / 57 Deafness, Hearing loss, Hereditary hearing loss, Isolated sensorineural deafness and 2 more
PTPRQ 6 / 57 Congenital ear anomaly, Deafness, Hearing loss, Isolated sensorineural deafness and 2 more
RDX 6 / 57 Deafness, Hearing loss, Hereditary hearing loss, Isolated sensorineural deafness and 2 more
SLC26A4 6 / 57 Congenital ear anomaly, Deafness, Hearing loss, Hereditary hearing loss and 2 more
SLC44A4 6 / 57 Deafness, Hearing loss, Isolated sensorineural deafness, Nonsyndromic genetic hearing loss and 2 more
STRC 6 / 57 Deafness, Hearing loss, Hereditary hearing loss, Isolated sensorineural deafness and 2 more
TNC 6 / 57 Deafness, Hearing loss, Isolated sensorineural deafness, Meniere disease and 2 more
TRIOBP 6 / 57 Deafness, Hearing loss, Hereditary hearing loss, Isolated sensorineural deafness and 2 more
ADCY1 5 / 57 Deafness, Hearing loss, Isolated sensorineural deafness, Nonsyndromic genetic hearing loss and 1 more
ADGRV1 5 / 57 Congenital ear anomaly, Deafness, Hearing loss, Meniere disease and 1 more
ATP2B2 5 / 57 Autosomal dominant nonsyndromic hearing loss, Deafness, Hearing loss, Isolated sensorineural deafness and 1 more
CLIC5 5 / 57 Deafness, Deafness, autosomal recessive 103, Hearing loss, Isolated sensorineural deafness and 1 more
CRYM 5 / 57 Deafness, Deafness, autosomal dominant 40, Isolated sensorineural deafness, Nonsyndromic genetic hearing loss and 1 more
DIAPH1 5 / 57 Auditory neuropathy, Deafness, Hearing loss, Hereditary hearing loss and 1 more
DIAPH3 5 / 57 Auditory neuropathy, Auditory neuropathy, autosomal dominant, 1, Hearing loss, Isolated sensorineural deafness and 1 more
DMXL2 5 / 57 Deafness, Hearing loss, Isolated sensorineural deafness, Nonsyndromic genetic hearing loss and 1 more
GJB3 5 / 57 Deafness, Hearing loss, Hereditary hearing loss, Isolated sensorineural deafness and 1 more
GJB6 5 / 57 Deafness, Hearing loss, Hereditary hearing loss, Isolated sensorineural deafness and 1 more
GRXCR2 5 / 57 Deafness, Hearing loss, Isolated sensorineural deafness, Nonsyndromic genetic hearing loss and 1 more
HOMER2 5 / 57 Deafness, Deafness, autosomal dominant 68, Isolated sensorineural deafness, Nonsyndromic genetic hearing loss and 1 more
ILDR1 5 / 57 Deafness, Hearing loss, Isolated sensorineural deafness, Nonsyndromic genetic hearing loss and 1 more
MCM2 5 / 57 Deafness, Deafness, autosomal dominant, 70, Isolated sensorineural deafness, Nonsyndromic genetic hearing loss and 1 more
MINAR2 5 / 57 Deafness, Hearing loss, Hearing loss, autosomal recessive 120, Isolated sensorineural deafness and 1 more
MPZL2 5 / 57 Deafness, Deafness, autosomal recessive 111, Hearing loss, Isolated sensorineural deafness and 1 more
P2RX2 5 / 57 Deafness, Deafness, autosomal dominant 41, Isolated sensorineural deafness, Nonsyndromic genetic hearing loss and 1 more
PDE1C 5 / 57 Autosomal dominant nonsyndromic hearing loss, Deafness, Hearing loss, Isolated sensorineural deafness and 1 more
PLS1 5 / 57 Autosomal dominant nonsyndromic hearing loss, Deafness, Hearing loss, Isolated sensorineural deafness and 1 more
PNPT1 5 / 57 Deafness, Hearing loss, Isolated sensorineural deafness, Nonsyndromic hearing loss and 1 more
ROR1 5 / 57 Deafness, Deafness, autosomal recessive 108, Hearing loss, Isolated sensorineural deafness and 1 more
SIX1 5 / 57 Deafness, Hearing loss, Hereditary hearing loss, Isolated sensorineural deafness and 1 more
TBCEL-TECTA 5 / 57 Congenital ear anomaly, Deafness, Hearing loss, Meniere disease and 1 more
TJP2 5 / 57 Deafness, Hearing loss, Isolated sensorineural deafness, Nonsyndromic genetic hearing loss and 1 more
TMTC4 5 / 57 Deafness, Hearing loss, Isolated sensorineural deafness, Nonsyndromic hearing loss and 1 more
USH2A 5 / 57 Congenital ear anomaly, Deafness, Hearing loss, Retinitis pigmentosa-deafness syndrome and 1 more
AFG2B 4 / 57 Deafness, Hearing loss, Isolated sensorineural deafness, Nonsyndromic hearing loss
BDP1 4 / 57 Deafness, Hearing loss, Isolated sensorineural deafness, Nonsyndromic genetic hearing loss
What do these columns mean?
Connections in cluster
How many other members this disease has a shared-gene link to (the node size in the network above). The most-connected diseases are the cluster's core.
Significant partners
How many of those links are statistically significant (FDR q < 0.05).
Curated genes
Distinct curated genes linked to that disease in GeDiPNet.
Member diseases (Top shared genes)
How many of this cluster's diseases are linked to the gene, out of the cluster's total. Genes shared by many members are the most direct explanation of why they group together.
Overlap genes (x / y)
x = genes shared between this cluster and the pathway/GO term; y = that pathway/GO term's total gene count. A higher x relative to y (and to the cluster's own size) means a tighter biological match.
Cluster gene count
Total distinct genes across every disease in this cluster -- the "n" used in the significance test below.
Fold enrichment
Observed overlap divided by the overlap expected by chance, given the cluster's gene count, the pathway/term's size and the gene universe tested. 5× means five times more shared genes than random. Tells strong hits apart when q-values are all vanishingly small.
P-value / FDR q-value
Is this pathway/GO term's overlap with the cluster more than chance? Upper-tail hypergeometric test, Benjamini-Hochberg corrected across every tested pathway/term (prefer the q-value -- it accounts for testing many at once).
Shared genes (Pairs within this cluster)
Number of curated genes the two diseases in that row have in common.
Similarity score (Pairs within this cluster)
Jaccard-based gene overlap between the two specific diseases in that row -- same metric as the main Shared-Gene Disease Pairs page.

Enriched Pathways (why this cluster is grouped, biologically)

Pathway ⇵ Source ⇵ Overlap genes ⇵ Fold enrichment ⇵ P-value ⇵ FDR q-value ⇵
Trafficking of AMPA receptors
MYO6, CACNG2, CAMK2A, CAMK2B, EPB41L1, GRIA1, DLG4
 Reactome 7 / 17 7.6× 1.59e-5 4.30e-4 ✓ sig.
NCAM1 interactions
COL2A1, COL4A3, COL4A4, COL4A5, COL9A1, COL9A3, COL9A2
 Reactome 7 / 21 6.2× 7.86e-5 1.56e-3 ✓ sig.
Unblocking of NMDA receptors, glutamate binding and activation
NEFL, CAMK2A, CAMK2B, GRIA1, GRIN1, GRIN2B, DLG4
 Reactome 7 / 22 5.9× 1.10e-4 2.05e-3 ✓ sig.
Cytoskeleton in muscle cells
DIAPH3, DIAPH1, TMEM43, ACTG1, COL11A1, COL11A2, MYH14, MYH9, FMN2, OBSCN, COL4A3, COL4A4
 KEGG 27 / 232 2.2× 1.41e-4 2.49e-3 ✓ sig.
Signaling by PDGF
COL2A1, COL4A3, COL4A4, COL4A5, COL9A1, COL9A3, THBS1, COL9A2
 Reactome 8 / 33 4.5× 2.93e-4 4.43e-3 ✓ sig.
Collagen chain trimerization
COL11A1, COL11A2, COL2A1, COL4A3, COL4A4, COL4A5, COL9A1, COL9A3, COL9A2
 Reactome 9 / 44 3.8× 4.85e-4 6.52e-3 ✓ sig.
Glutamatergic synapse
CACNA1A, SLC17A8, HOMER2, GNB1, GRIA1, GRIN1, GRIN2B, PPP3CA, ADCY1, GRIK2, GRM7, NCDN
 KEGG 16 / 116 2.5× 4.98e-4 6.67e-3 ✓ sig.
MET activates PTK2 signaling
COL11A1, COL11A2, HGF, MET, COL2A1, PTK2, ITGA2
 Reactome 7 / 30 4.3× 8.99e-4 1.05e-2 ✓ sig.
Leishmaniasis
EEF1A2, STAT1, TLR4, HLA-DQA1, HLA-DQB1, HLA-DRA, HLA-DRB1, ITGAM, NFKBIA, IFNG, TNF, PRKCB
 KEGG 12 / 78 2.8× 9.27e-4 1.07e-2 ✓ sig.
Allograft rejection
HLA-DQA1, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-B, IFNG, IL2, TNF
 KEGG 8 / 39 3.8× 9.74e-4 1.11e-2 ✓ sig.
RAF/MAP kinase cascade
NEFL, KITLG, CAMK2A, CAMK2B, ERBB4, GRIN1, GRIN2B, HGF, MET, DLG4, PTK2, SPTBN1
 Reactome 16 / 124 2.4× 1.04e-3 1.17e-2 ✓ sig.
Recycling pathway of L1
TUBB4A, ACTG1, CLTC, DPYSL2, RDX, EZR, TUBB1, ACTB
 Reactome 8 / 40 3.7× 1.16e-3 1.27e-2 ✓ sig.
Integrin cell surface interactions
TNC, COL2A1, COL4A3, COL4A4, COL4A5, COL9A1, COL9A3, THBS1, ITGA1, ITGAM, COL9A2, ITGA2
 Reactome 12 / 81 2.7× 1.30e-3 1.39e-2 ✓ sig.
Cytosolic tRNA aminoacylation
KARS1, AIMP1, SARS1, EEF1E1, HARS1, LARS1
 Reactome 6 / 24 4.6× 1.43e-3 1.48e-2 ✓ sig.
Non-integrin membrane-ECM interactions
COL11A1, COL11A2, COL2A1, COL4A3, COL4A4, COL4A5
 Reactome 6 / 24 4.6× 1.43e-3 1.48e-2 ✓ sig.

Enriched GO Terms (Biological Process, a second line of biological evidence)

GO term ⇵ GO ID ⇵ Overlap genes ⇵ Fold enrichment ⇵ P-value ⇵ FDR q-value ⇵
sensory perception of sound
DIAPH3, MYO7A, OTOF, SLC52A3, WFS1, DIAPH1, SLC17A8, ATP2B2, CCDC50, CEACAM16, COCH, COL11A1
 GO:0007605 95 / 162 16.9× 1.08e-96 2.06e-91 ✓ sig.
auditory receptor cell stereocilium organization
MYO7A, PLS1, TECTA, REST, CDH23, CLRN2, GRXCR1, GRXCR2, LHFPL5, STRC, TPRN, TRIOBP
 GO:0060088 16 / 19 24.2× 3.37e-21 6.62e-18 ✓ sig.
inner ear morphogenesis
MYO7A, COL11A1, KCNQ4, MYO6, POU4F3, SIX1, CDH23, MYO15A, SLITRK6, TMIE, USH1C, FOXI1
 GO:0042472 22 / 65 9.7× 1.71e-16 1.60e-13 ✓ sig.
inner ear auditory receptor cell differentiation
MYO7A, GSDME, MYO6, POU4F3, DLL1, CDH23, CLRN2, GRXCR1, MINAR2, USH1C, USH2A, JAG1
 GO:0042491 13 / 19 19.7× 2.17e-15 1.67e-12 ✓ sig.
inner ear receptor cell differentiation
DIAPH3, MYO7A, POU4F3, MINAR2, WHRN, ADGRV1, PDZD7, USH2A, USH1G
 GO:0060113 9 / 9 28.7× 7.06e-14 4.19e-11 ✓ sig.
inner ear development
MYO7A, EYA4, GJB6, POU4F3, SIX1, DLL1, CDH23, ESRRB, GRXCR1, PCDH15, ROR1, ADGRV1
 GO:0048839 18 / 54 9.6× 1.33e-13 7.44e-11 ✓ sig.
detection of mechanical stimulus involved in sensory perception of sound
COL11A1, PTPRQ, TMC1, REST, LHFPL5, PJVK, STRC, WHRN, ADGRV1, KCNQ1, PDZD7
 GO:0050910 11 / 18 17.6× 2.12e-12 9.45e-10 ✓ sig.
visual perception
MYO7A, OPA1, WFS1, COL11A1, EYA4, POU4F3, CABP2, CDH23, CLIC5, MYO3A, SLITRK6, KCNJ10
 GO:0007601 32 / 215 4.3× 3.65e-12 1.54e-9 ✓ sig.
photoreceptor cell maintenance
CDH23, CIB2, ESRRB, PCDH15, USH1C, ADGRV1, USH2A, USH1G, CLRN1, ERCC6, BBS2, TUB
 GO:0045494 15 / 45 9.6× 1.47e-11 5.42e-9 ✓ sig.
sensory perception of light stimulus
MYO7A, CDH23, PCDH15, USH1C, WHRN, ADGRV1, USH2A, USH1G, CLRN1
 GO:0050953 9 / 13 19.9× 4.46e-11 1.48e-8 ✓ sig.
inner ear receptor cell stereocilium organization
MYO7A, CDH23, GRXCR1, GRXCR2, MINAR2, OTOGL, STRC, USH1C, WHRN, ADGRV1, USH1G
 GO:0060122 11 / 25 12.6× 2.37e-10 6.64e-8 ✓ sig.
equilibrioception
MYO7A, CDH23, PCDH15, USH1C, USH1G, CLRN1
 GO:0050957 6 / 6 28.7× 1.73e-9 3.75e-7 ✓ sig.
auditory receptor cell development
TMC1, ELMOD3, KCNQ1, PDZD7, CLRN1, PAFAH1B1
 GO:0060117 6 / 8 21.6× 4.57e-8 6.57e-6 ✓ sig.
olfactory behavior
WFS1, LMX1A, GJB4, ATP6V1B1, CHD7, BBS1
 GO:0042048 6 / 9 19.2× 1.33e-7 1.61e-5 ✓ sig.
cochlea development
MYO7A, SLC17A8, MCM2, CDH23, GRXCR1, SLC26A5, SLITRK6, KCNQ1, GATA3, PAFAH1B1
 GO:0090102 10 / 35 8.2× 2.02e-7 2.28e-5 ✓ sig.

Pairs within this cluster, by significance

Disease A ⇵ Disease B ⇵ Similarity score ⇵ Shared genes ⇵ P-value ⇵ FDR q-value ⇵
Deafness Isolated sensorineural deafness 0.623 114 1.05e-234 7.98e-233 ✓ sig.
Isolated sensorineural deafness Nonsyndromic hearing loss 0.732 101 7.06e-222 5.20e-220 ✓ sig.
Deafness Nonsyndromic hearing loss 0.563 107 1.78e-210 1.26e-208 ✓ sig.
Deafness Hearing loss 0.307 135 7.00e-186 4.65e-184 ✓ sig.
Isolated sensorineural deafness Nonsyndromic genetic hearing loss 0.629 78 5.31e-174 3.29e-172 ✓ sig.
Hearing loss Isolated sensorineural deafness 0.261 107 8.55e-162 5.07e-160 ✓ sig.
Deafness Nonsyndromic genetic hearing loss 0.436 79 3.85e-158 2.24e-156 ✓ sig.
Nonsyndromic genetic hearing loss Nonsyndromic hearing loss 0.554 72 1.10e-152 6.25e-151 ✓ sig.
Hearing loss Nonsyndromic hearing loss 0.237 99 1.04e-141 5.66e-140 ✓ sig.
Hearing loss Nonsyndromic genetic hearing loss 0.182 74 4.47e-111 2.06e-109 ✓ sig.
Hereditary hearing loss Nonsyndromic hearing loss 0.382 47 2.22e-100 9.31e-99 ✓ sig.
Deafness Hereditary hearing loss 0.267 48 6.93e-94 2.74e-92 ✓ sig.
Hereditary hearing loss Isolated sensorineural deafness 0.349 44 1.61e-90 6.17e-89 ✓ sig.
Hereditary hearing loss Nonsyndromic genetic hearing loss 0.415 39 1.16e-83 4.25e-82 ✓ sig.
Hearing loss Hereditary hearing loss 0.120 48 2.73e-75 9.36e-74 ✓ sig.
Congenital ear anomaly Isolated sensorineural deafness 0.162 21 2.56e-38 5.85e-37 ✓ sig.
Congenital ear anomaly Nonsyndromic hearing loss 0.162 21 2.56e-38 5.85e-37 ✓ sig.
Congenital ear anomaly Nonsyndromic genetic hearing loss 0.200 19 8.02e-37 1.80e-35 ✓ sig.
Congenital ear anomaly Hereditary hearing loss 0.262 17 5.36e-36 1.18e-34 ✓ sig.
Retinitis pigmentosa-deafness syndrome Usher syndrome 0.217 10 1.25e-25 2.17e-24 ✓ sig.
Autosomal dominant nonsyndromic hearing loss Isolated sensorineural deafness 0.091 11 4.09e-23 6.59e-22 ✓ sig.
Autosomal dominant nonsyndromic hearing loss Nonsyndromic hearing loss 0.091 11 4.09e-23 6.59e-22 ✓ sig.
Nonsyndromic hearing loss Nonsyndromic intellectual disability 0.092 22 6.75e-23 1.08e-21 ✓ sig.
Deafness Usher syndrome 0.083 17 2.32e-22 3.66e-21 ✓ sig.
Isolated sensorineural deafness Nonsyndromic intellectual disability 0.087 21 1.92e-21 2.94e-20 ✓ sig.
Nonsyndromic genetic hearing loss Nonsyndromic intellectual disability 0.087 18 2.47e-20 3.66e-19 ✓ sig.
Isolated sensorineural deafness Meniere disease 0.093 16 5.48e-20 8.01e-19 ✓ sig.
Meniere disease Nonsyndromic hearing loss 0.093 16 5.48e-20 8.01e-19 ✓ sig.
Meniere disease Nonsyndromic genetic hearing loss 0.086 12 1.20e-15 1.50e-14 ✓ sig.
Hereditary hearing loss Meniere disease 0.092 10 1.19e-14 1.42e-13 ✓ sig.
Nonsyndromic genetic hearing loss Usher syndrome 0.085 10 2.11e-14 2.48e-13 ✓ sig.
Congenital ear anomaly Meniere disease 0.087 8 6.57e-13 7.14e-12 ✓ sig.
Hereditary hearing loss Usher syndrome 0.092 8 1.06e-12 1.14e-11 ✓ sig.
Auditory neuropathy Nonsyndromic hearing loss 0.063 9 1.20e-12 1.29e-11 ✓ sig.
Congenital ear anomaly Usher syndrome 0.101 7 2.26e-12 2.37e-11 ✓ sig.
Congenital ear anomaly Retinitis pigmentosa-deafness syndrome 0.132 5 1.05e-11 1.06e-10 ✓ sig.
Auditory neuropathy Hereditary hearing loss 0.065 5 4.55e-8 3.36e-7 ✓ sig.
Auditory neuropathy Congenital ear anomaly 0.068 4 3.98e-7 2.56e-6 ✓ sig.
Autosomal dominant nonsyndromic hearing loss Deafness, autosomal dominant 21 0.077 1 7.75e-4 1.25e-3 ✓ sig.
Autosomal dominant nonsyndromic hearing loss Deafness, autosomal dominant 7 0.077 1 7.75e-4 1.25e-3 ✓ sig.
Autosomal dominant nonsyndromic hearing loss Deafness, autosomal dominant, 77 0.077 1 7.75e-4 1.25e-3 ✓ sig.
Auditory neuropathy Auditory neuropathy, autosomal dominant, 1 0.031 1 2.00e-3 2.72e-3 ✓ sig.
Auditory neuropathy Deafness, autosomal dominant 25 0.031 1 2.00e-3 2.72e-3 ✓ sig.
Congenital ear anomaly Deafness, autosomal recessive 49 0.031 1 2.00e-3 2.72e-3 ✓ sig.
Congenital ear anomaly Deafness, autosomal recessive 67 0.031 1 2.00e-3 2.72e-3 ✓ sig.
Congenital ear anomaly Deafness, autosomal recessive 79 0.031 1 2.00e-3 2.72e-3 ✓ sig.
Deafness, autosomal recessive 22 Usher syndrome 0.022 1 2.84e-3 3.63e-3 ✓ sig.
Deafness, autosomal recessive 91 Usher syndrome 0.022 1 2.84e-3 3.63e-3 ✓ sig.
Deafness, autosomal dominant 25 Hereditary hearing loss 0.020 1 3.23e-3 4.07e-3 ✓ sig.
Deafness, autosomal dominant 2a Hereditary hearing loss 0.020 1 3.23e-3 4.07e-3 ✓ sig.
Deafness, autosomal dominant 44 Hereditary hearing loss 0.020 1 3.23e-3 4.07e-3 ✓ sig.
Deafness, autosomal recessive 22 Hereditary hearing loss 0.020 1 3.23e-3 4.07e-3 ✓ sig.
Deafness, autosomal recessive 35 Hereditary hearing loss 0.020 1 3.23e-3 4.07e-3 ✓ sig.
Deafness, autosomal recessive 49 Hereditary hearing loss 0.020 1 3.23e-3 4.07e-3 ✓ sig.
Deafness, autosomal recessive 67 Hereditary hearing loss 0.020 1 3.23e-3 4.07e-3 ✓ sig.
Deafness, autosomal recessive 77 Hereditary hearing loss 0.020 1 3.23e-3 4.07e-3 ✓ sig.
Deafness, autosomal recessive 106 Meniere disease 0.014 1 4.39e-3 5.34e-3 ✓ sig.
Deafness, autosomal recessive 18b Meniere disease 0.014 1 4.39e-3 5.34e-3 ✓ sig.
Deafness, autosomal dominant 21 Nonsyndromic genetic hearing loss 0.012 1 5.29e-3 6.29e-3 ✓ sig.
Deafness, autosomal dominant 25 Nonsyndromic genetic hearing loss 0.012 1 5.29e-3 6.29e-3 ✓ sig.
Deafness, autosomal dominant 2a Nonsyndromic genetic hearing loss 0.012 1 5.29e-3 6.29e-3 ✓ sig.
Deafness, autosomal dominant 40 Nonsyndromic genetic hearing loss 0.012 1 5.29e-3 6.29e-3 ✓ sig.
Deafness, autosomal dominant 41 Nonsyndromic genetic hearing loss 0.012 1 5.29e-3 6.29e-3 ✓ sig.
Deafness, autosomal dominant 44 Nonsyndromic genetic hearing loss 0.012 1 5.29e-3 6.29e-3 ✓ sig.
Deafness, autosomal dominant 50 Nonsyndromic genetic hearing loss 0.012 1 5.29e-3 6.29e-3 ✓ sig.
Deafness, autosomal dominant 64 Nonsyndromic genetic hearing loss 0.012 1 5.29e-3 6.29e-3 ✓ sig.
Deafness, autosomal dominant 68 Nonsyndromic genetic hearing loss 0.012 1 5.29e-3 6.29e-3 ✓ sig.
Deafness, autosomal dominant, 70 Nonsyndromic genetic hearing loss 0.012 1 5.29e-3 6.29e-3 ✓ sig.
Deafness, autosomal recessive 106 Nonsyndromic genetic hearing loss 0.012 1 5.29e-3 6.29e-3 ✓ sig.
Deafness, autosomal recessive 108 Nonsyndromic genetic hearing loss 0.012 1 5.29e-3 6.29e-3 ✓ sig.
Deafness, autosomal recessive 109 Nonsyndromic genetic hearing loss 0.012 1 5.29e-3 6.29e-3 ✓ sig.
Deafness, autosomal recessive 111 Nonsyndromic genetic hearing loss 0.012 1 5.29e-3 6.29e-3 ✓ sig.
Deafness, autosomal recessive 117 Nonsyndromic genetic hearing loss 0.012 1 5.29e-3 6.29e-3 ✓ sig.
Deafness, autosomal recessive 15 Nonsyndromic genetic hearing loss 0.012 1 5.29e-3 6.29e-3 ✓ sig.
Deafness, autosomal recessive 18b Nonsyndromic genetic hearing loss 0.012 1 5.29e-3 6.29e-3 ✓ sig.
Deafness, autosomal recessive 22 Nonsyndromic genetic hearing loss 0.012 1 5.29e-3 6.29e-3 ✓ sig.
Deafness, autosomal recessive 25 Nonsyndromic genetic hearing loss 0.012 1 5.29e-3 6.29e-3 ✓ sig.
Deafness, autosomal recessive 35 Nonsyndromic genetic hearing loss 0.012 1 5.29e-3 6.29e-3 ✓ sig.
Deafness, autosomal recessive 49 Nonsyndromic genetic hearing loss 0.012 1 5.29e-3 6.29e-3 ✓ sig.
Deafness, autosomal recessive 61 Nonsyndromic genetic hearing loss 0.012 1 5.29e-3 6.29e-3 ✓ sig.
Deafness, autosomal recessive 67 Nonsyndromic genetic hearing loss 0.012 1 5.29e-3 6.29e-3 ✓ sig.
Deafness, autosomal recessive 68 Nonsyndromic genetic hearing loss 0.012 1 5.29e-3 6.29e-3 ✓ sig.
Deafness, autosomal recessive 74 Nonsyndromic genetic hearing loss 0.012 1 5.29e-3 6.29e-3 ✓ sig.
Deafness, autosomal recessive 76 Nonsyndromic genetic hearing loss 0.012 1 5.29e-3 6.29e-3 ✓ sig.
Deafness, autosomal recessive 77 Nonsyndromic genetic hearing loss 0.012 1 5.29e-3 6.29e-3 ✓ sig.
Deafness, autosomal recessive 79 Nonsyndromic genetic hearing loss 0.012 1 5.29e-3 6.29e-3 ✓ sig.
Deafness, autosomal recessive 91 Nonsyndromic genetic hearing loss 0.012 1 5.29e-3 6.29e-3 ✓ sig.
Deafness, autosomal recessive 93 Nonsyndromic genetic hearing loss 0.012 1 5.29e-3 6.29e-3 ✓ sig.
Nonsyndromic genetic hearing loss Pancreas adenocarcinoma 0.012 1 5.29e-3 6.29e-3 ✓ sig.
Auditory neuropathy, autosomal dominant, 1 Isolated sensorineural deafness 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Auditory neuropathy, autosomal dominant, 1 Nonsyndromic hearing loss 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal dominant 21 Isolated sensorineural deafness 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal dominant 21 Nonsyndromic hearing loss 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal dominant 25 Isolated sensorineural deafness 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal dominant 25 Nonsyndromic hearing loss 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal dominant 2a Isolated sensorineural deafness 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal dominant 2a Nonsyndromic hearing loss 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal dominant 40 Isolated sensorineural deafness 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal dominant 40 Nonsyndromic hearing loss 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal dominant 41 Isolated sensorineural deafness 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal dominant 41 Nonsyndromic hearing loss 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal dominant 44 Isolated sensorineural deafness 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal dominant 44 Nonsyndromic hearing loss 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal dominant 64 Isolated sensorineural deafness 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal dominant 64 Nonsyndromic hearing loss 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal dominant 68 Isolated sensorineural deafness 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal dominant 68 Nonsyndromic hearing loss 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal dominant, 70 Isolated sensorineural deafness 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal dominant, 70 Nonsyndromic hearing loss 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal dominant, 77 Isolated sensorineural deafness 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal recessive 103 Isolated sensorineural deafness 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal recessive 103 Nonsyndromic hearing loss 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal recessive 106 Isolated sensorineural deafness 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal recessive 108 Isolated sensorineural deafness 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal recessive 111 Isolated sensorineural deafness 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal recessive 117 Isolated sensorineural deafness 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal recessive 117 Nonsyndromic hearing loss 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal recessive 15 Isolated sensorineural deafness 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal recessive 15 Nonsyndromic hearing loss 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal recessive 18b Isolated sensorineural deafness 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal recessive 18b Nonsyndromic hearing loss 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal recessive 22 Isolated sensorineural deafness 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal recessive 22 Nonsyndromic hearing loss 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal recessive 25 Isolated sensorineural deafness 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal recessive 25 Nonsyndromic hearing loss 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal recessive 35 Isolated sensorineural deafness 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal recessive 35 Nonsyndromic hearing loss 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal recessive 49 Isolated sensorineural deafness 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal recessive 49 Nonsyndromic hearing loss 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal recessive 61 Isolated sensorineural deafness 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal recessive 61 Nonsyndromic hearing loss 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal recessive 67 Isolated sensorineural deafness 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal recessive 67 Nonsyndromic hearing loss 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal recessive 68 Isolated sensorineural deafness 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal recessive 68 Nonsyndromic hearing loss 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal recessive 74 Isolated sensorineural deafness 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal recessive 74 Nonsyndromic hearing loss 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal recessive 76 Isolated sensorineural deafness 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal recessive 76 Nonsyndromic hearing loss 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal recessive 77 Isolated sensorineural deafness 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal recessive 77 Nonsyndromic hearing loss 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal recessive 79 Isolated sensorineural deafness 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal recessive 79 Nonsyndromic hearing loss 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal recessive 91 Isolated sensorineural deafness 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal recessive 91 Nonsyndromic hearing loss 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal recessive 93 Isolated sensorineural deafness 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Deafness, autosomal recessive 93 Nonsyndromic hearing loss 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Hearing loss, autosomal recessive 120 Isolated sensorineural deafness 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Hearing loss, autosomal recessive 120 Nonsyndromic hearing loss 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Isolated sensorineural deafness Pancreas adenocarcinoma 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Nonsyndromic hearing loss Pancreas adenocarcinoma 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Isolated sensorineural deafness Worster drought syndrome 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Nonsyndromic hearing loss Worster drought syndrome 0.008 1 7.68e-3 8.81e-3 ✓ sig.
Al-raqad syndrome Nonsyndromic intellectual disability 0.007 1 9.17e-3 1.03e-2 ✓ sig.
Deafness, autosomal recessive 61 Nonsyndromic intellectual disability 0.007 1 9.17e-3 1.03e-2 ✓ sig.
Deafness, autosomal recessive 68 Nonsyndromic intellectual disability 0.007 1 9.17e-3 1.03e-2 ✓ sig.
Deafness, autosomal recessive 76 Nonsyndromic intellectual disability 0.007 1 9.17e-3 1.03e-2 ✓ sig.
Deafness, autosomal recessive 79 Nonsyndromic intellectual disability 0.007 1 9.17e-3 1.03e-2 ✓ sig.
Deafness, autosomal recessive 93 Nonsyndromic intellectual disability 0.007 1 9.17e-3 1.03e-2 ✓ sig.
Mental retardation, autosomal recessive 56 Nonsyndromic intellectual disability 0.007 1 9.17e-3 1.03e-2 ✓ sig.
Neurodevelopmental disorder with cerebral atrophy and variable facial dysmorphism Nonsyndromic intellectual disability 0.007 1 9.17e-3 1.03e-2 ✓ sig.
Neurodevelopmental disorder with hypotonia and gross motor and speech delay Nonsyndromic intellectual disability 0.007 1 9.17e-3 1.03e-2 ✓ sig.
Deafness Deafness, autosomal dominant 21 0.006 1 1.14e-2 1.27e-2 ✓ sig.
Deafness Deafness, autosomal dominant 2a 0.006 1 1.14e-2 1.27e-2 ✓ sig.
Deafness Deafness, autosomal dominant 40 0.006 1 1.14e-2 1.27e-2 ✓ sig.
Deafness Deafness, autosomal dominant 41 0.006 1 1.14e-2 1.27e-2 ✓ sig.
Deafness Deafness, autosomal dominant 44 0.006 1 1.14e-2 1.27e-2 ✓ sig.
Deafness Deafness, autosomal dominant 68 0.006 1 1.14e-2 1.27e-2 ✓ sig.
Deafness Deafness, autosomal dominant, 70 0.006 1 1.14e-2 1.27e-2 ✓ sig.
Deafness Deafness, autosomal dominant, 79 0.006 1 1.14e-2 1.27e-2 ✓ sig.
Deafness Deafness, autosomal recessive 103 0.006 1 1.14e-2 1.27e-2 ✓ sig.
Deafness Deafness, autosomal recessive 106 0.006 1 1.14e-2 1.27e-2 ✓ sig.
Deafness Deafness, autosomal recessive 108 0.006 1 1.14e-2 1.27e-2 ✓ sig.
Deafness Deafness, autosomal recessive 109 0.006 1 1.14e-2 1.27e-2 ✓ sig.
Deafness Deafness, autosomal recessive 111 0.006 1 1.14e-2 1.27e-2 ✓ sig.
Deafness Deafness, autosomal recessive 117 0.006 1 1.14e-2 1.27e-2 ✓ sig.
Deafness Deafness, autosomal recessive 15 0.006 1 1.14e-2 1.27e-2 ✓ sig.
Deafness Deafness, autosomal recessive 18b 0.006 1 1.14e-2 1.27e-2 ✓ sig.
Deafness Deafness, autosomal recessive 25 0.006 1 1.14e-2 1.27e-2 ✓ sig.
Deafness Deafness, autosomal recessive 35 0.006 1 1.14e-2 1.27e-2 ✓ sig.
Deafness Deafness, autosomal recessive 61 0.006 1 1.14e-2 1.27e-2 ✓ sig.
Deafness Deafness, autosomal recessive 76 0.006 1 1.14e-2 1.27e-2 ✓ sig.
Deafness Deafness, autosomal recessive 93 0.006 1 1.14e-2 1.27e-2 ✓ sig.
Deafness Hearing loss, autosomal recessive 115 0.006 1 1.14e-2 1.27e-2 ✓ sig.
Deafness Hearing loss, autosomal recessive 120 0.006 1 1.14e-2 1.27e-2 ✓ sig.
Deafness Worster drought syndrome 0.006 1 1.14e-2 1.27e-2 ✓ sig.
Deafness, autosomal dominant, 79 Hearing loss 0.003 1 2.56e-2 2.72e-2 ✓ sig.
Deafness, autosomal recessive 106 Hearing loss 0.003 1 2.56e-2 2.72e-2 ✓ sig.
Deafness, autosomal recessive 108 Hearing loss 0.003 1 2.56e-2 2.72e-2 ✓ sig.
Deafness, autosomal recessive 109 Hearing loss 0.003 1 2.56e-2 2.72e-2 ✓ sig.
Deafness, autosomal recessive 111 Hearing loss 0.003 1 2.56e-2 2.72e-2 ✓ sig.
Deafness, autosomal recessive 117 Hearing loss 0.003 1 2.56e-2 2.72e-2 ✓ sig.
Deafness, autosomal recessive 15 Hearing loss 0.003 1 2.56e-2 2.72e-2 ✓ sig.
Deafness, autosomal recessive 25 Hearing loss 0.003 1 2.56e-2 2.72e-2 ✓ sig.
Hearing loss Hearing loss, autosomal recessive 115 0.003 1 2.56e-2 2.72e-2 ✓ sig.
Hearing loss Hearing loss, autosomal recessive 120 0.003 1 2.56e-2 2.72e-2 ✓ sig.
Hearing loss Otofacial neurodevelopmental syndrome 0.003 1 2.56e-2 2.72e-2 ✓ sig.
Hearing loss Worster drought syndrome 0.003 1 2.56e-2 2.72e-2 ✓ sig.