Disease Clusters?

Groups of diseases that share a large number of curated genes with each other, computed via label propagation over the shared-gene similarity graph. See also Shared-Gene Disease Pairs for pairwise comparisons.

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Cluster 79

14 diseases · 30 shared-gene connections
14 Diseases
193 Unique genes
0.209 Avg. similarity score
Malignant peripheral nerve sheath tumor Most-connected disease (7 links)
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Disease Searched: Clear cell sarcoma Pinned (dragged)
Node size = connections within this cluster · edge thickness = similarity strength · hover an edge for its details · click a node to select it and show its pairs below (double-click or Ctrl/⌘-click opens the disease page) · drag a node to pin it in place · scroll/pinch to zoom.

Member diseases (most connected first ‐ the cluster's core)

Disease ⇵ Connections in cluster ⇵ Significant partners ⇵ Curated genes ⇵
Malignant peripheral nerve sheath tumor 7 7 51
Clear cell sarcoma 6 6 26
Malignant soft tissue neoplasm 6 6 25
Soft tissue sarcoma 6 6 69
Synovial sarcoma 6 6 77
Desmoplastic small round cell tumor 5 5 34
Solitary fibrous tumor 5 5 34
Extraskeletal myxoid chondrosarcoma 4 4 29
Neurofibroma 4 4 20
Dermatofibrosarcoma protuberans 3 3 20
Lipoma 3 3 27
Spindle cell rhabdomyosarcoma 3 3 13
Myopathy, congenital, with diaphragmatic defects, respiratory insufficiency, and dysmorphic facies 1 1 1
Uterine benign neoplasm 1 1 1

Top shared genes (genes linked to 2+ member diseases)

Gene ⇵ Member diseases ⇵ Linked diseases
CREB3L2 9 / 14 Dermatofibrosarcoma protuberans, Extraskeletal myxoid chondrosarcoma, Lipoma, Malignant peripheral nerve sheath tumor and 5 more
FUS 9 / 14 Dermatofibrosarcoma protuberans, Extraskeletal myxoid chondrosarcoma, Lipoma, Malignant peripheral nerve sheath tumor and 5 more
SS18 9 / 14 Clear cell sarcoma, Desmoplastic small round cell tumor, Extraskeletal myxoid chondrosarcoma, Malignant peripheral nerve sheath tumor and 5 more
SSX1 9 / 14 Clear cell sarcoma, Desmoplastic small round cell tumor, Extraskeletal myxoid chondrosarcoma, Malignant peripheral nerve sheath tumor and 5 more
SSX2 9 / 14 Clear cell sarcoma, Desmoplastic small round cell tumor, Extraskeletal myxoid chondrosarcoma, Malignant peripheral nerve sheath tumor and 5 more
CREB3L1 8 / 14 Extraskeletal myxoid chondrosarcoma, Lipoma, Malignant peripheral nerve sheath tumor, Malignant soft tissue neoplasm and 4 more
ETV6 8 / 14 Clear cell sarcoma, Dermatofibrosarcoma protuberans, Desmoplastic small round cell tumor, Malignant peripheral nerve sheath tumor and 4 more
EWSR1 8 / 14 Clear cell sarcoma, Desmoplastic small round cell tumor, Extraskeletal myxoid chondrosarcoma, Lipoma and 4 more
NTRK3 8 / 14 Clear cell sarcoma, Dermatofibrosarcoma protuberans, Desmoplastic small round cell tumor, Malignant peripheral nerve sheath tumor and 4 more
TP53 8 / 14 Clear cell sarcoma, Dermatofibrosarcoma protuberans, Extraskeletal myxoid chondrosarcoma, Malignant peripheral nerve sheath tumor and 4 more
ALK 7 / 14 Dermatofibrosarcoma protuberans, Extraskeletal myxoid chondrosarcoma, Lipoma, Malignant peripheral nerve sheath tumor and 3 more
NPM1 7 / 14 Dermatofibrosarcoma protuberans, Extraskeletal myxoid chondrosarcoma, Lipoma, Malignant peripheral nerve sheath tumor and 3 more
PIK3CA 7 / 14 Desmoplastic small round cell tumor, Lipoma, Malignant peripheral nerve sheath tumor, Neurofibroma and 3 more
PTEN 7 / 14 Clear cell sarcoma, Dermatofibrosarcoma protuberans, Extraskeletal myxoid chondrosarcoma, Lipoma and 3 more
ERG 6 / 14 Clear cell sarcoma, Desmoplastic small round cell tumor, Malignant peripheral nerve sheath tumor, Malignant soft tissue neoplasm and 2 more
FLI1 6 / 14 Clear cell sarcoma, Desmoplastic small round cell tumor, Malignant peripheral nerve sheath tumor, Malignant soft tissue neoplasm and 2 more
FOXO1 6 / 14 Clear cell sarcoma, Desmoplastic small round cell tumor, Malignant soft tissue neoplasm, Soft tissue sarcoma and 2 more
PAX3 6 / 14 Clear cell sarcoma, Desmoplastic small round cell tumor, Malignant soft tissue neoplasm, Soft tissue sarcoma and 2 more
PAX7 6 / 14 Clear cell sarcoma, Desmoplastic small round cell tumor, Malignant soft tissue neoplasm, Soft tissue sarcoma and 2 more
WT1 6 / 14 Clear cell sarcoma, Desmoplastic small round cell tumor, Malignant soft tissue neoplasm, Soft tissue sarcoma and 2 more
ATF1 5 / 14 Clear cell sarcoma, Malignant peripheral nerve sheath tumor, Malignant soft tissue neoplasm, Soft tissue sarcoma and 1 more
DDIT3 5 / 14 Clear cell sarcoma, Extraskeletal myxoid chondrosarcoma, Lipoma, Malignant soft tissue neoplasm and 1 more
FGFR1 5 / 14 Dermatofibrosarcoma protuberans, Malignant peripheral nerve sheath tumor, Soft tissue sarcoma, Solitary fibrous tumor and 1 more
KMT2D 5 / 14 Extraskeletal myxoid chondrosarcoma, Malignant peripheral nerve sheath tumor, Solitary fibrous tumor, Spindle cell rhabdomyosarcoma and 1 more
NUTM2B 5 / 14 Clear cell sarcoma, Dermatofibrosarcoma protuberans, Malignant peripheral nerve sheath tumor, Solitary fibrous tumor and 1 more
YWHAE 5 / 14 Clear cell sarcoma, Dermatofibrosarcoma protuberans, Malignant peripheral nerve sheath tumor, Solitary fibrous tumor and 1 more
BRAF 4 / 14 Clear cell sarcoma, Malignant peripheral nerve sheath tumor, Soft tissue sarcoma, Synovial sarcoma
COL1A1 4 / 14 Dermatofibrosarcoma protuberans, Malignant peripheral nerve sheath tumor, Neurofibroma, Synovial sarcoma
EGFR 4 / 14 Clear cell sarcoma, Desmoplastic small round cell tumor, Soft tissue sarcoma, Synovial sarcoma
FAT1 4 / 14 Malignant peripheral nerve sheath tumor, Soft tissue sarcoma, Solitary fibrous tumor, Spindle cell rhabdomyosarcoma
NRAS 4 / 14 Clear cell sarcoma, Malignant peripheral nerve sheath tumor, Soft tissue sarcoma, Synovial sarcoma
PDGFB 4 / 14 Dermatofibrosarcoma protuberans, Malignant peripheral nerve sheath tumor, Neurofibroma, Synovial sarcoma
ROS1 4 / 14 Desmoplastic small round cell tumor, Extraskeletal myxoid chondrosarcoma, Soft tissue sarcoma, Synovial sarcoma
ARID2 3 / 14 Malignant peripheral nerve sheath tumor, Soft tissue sarcoma, Synovial sarcoma
BCOR 3 / 14 Malignant peripheral nerve sheath tumor, Spindle cell rhabdomyosarcoma, Synovial sarcoma
CDKN2A 3 / 14 Clear cell sarcoma, Malignant peripheral nerve sheath tumor, Soft tissue sarcoma
CIC 3 / 14 Desmoplastic small round cell tumor, Malignant soft tissue neoplasm, Soft tissue sarcoma
CTNNB1 3 / 14 Malignant peripheral nerve sheath tumor, Soft tissue sarcoma, Synovial sarcoma
ETV4 3 / 14 Malignant soft tissue neoplasm, Soft tissue sarcoma, Synovial sarcoma
KDR 3 / 14 Extraskeletal myxoid chondrosarcoma, Soft tissue sarcoma, Synovial sarcoma
KMT2C 3 / 14 Desmoplastic small round cell tumor, Spindle cell rhabdomyosarcoma, Synovial sarcoma
KRAS 3 / 14 Lipoma, Malignant peripheral nerve sheath tumor, Synovial sarcoma
MED12 3 / 14 Dermatofibrosarcoma protuberans, Malignant peripheral nerve sheath tumor, Synovial sarcoma
NF1 3 / 14 Dermatofibrosarcoma protuberans, Neurofibroma, Solitary fibrous tumor
PIK3R1 3 / 14 Soft tissue sarcoma, Solitary fibrous tumor, Synovial sarcoma
PTCH1 3 / 14 Extraskeletal myxoid chondrosarcoma, Malignant peripheral nerve sheath tumor, Soft tissue sarcoma
SMARCB1 3 / 14 Extraskeletal myxoid chondrosarcoma, Malignant peripheral nerve sheath tumor, Soft tissue sarcoma
SUZ12 3 / 14 Dermatofibrosarcoma protuberans, Malignant peripheral nerve sheath tumor, Solitary fibrous tumor
APC 2 / 14 Desmoplastic small round cell tumor, Solitary fibrous tumor
ARID1A 2 / 14 Extraskeletal myxoid chondrosarcoma, Neurofibroma
BET1L 2 / 14 Lipoma, Uterine benign neoplasm
CBL 2 / 14 Malignant peripheral nerve sheath tumor, Solitary fibrous tumor
CDH1 2 / 14 Soft tissue sarcoma, Synovial sarcoma
CDH11 2 / 14 Malignant peripheral nerve sheath tumor, Synovial sarcoma
CREB1 2 / 14 Clear cell sarcoma, Malignant soft tissue neoplasm
EED 2 / 14 Malignant peripheral nerve sheath tumor, Soft tissue sarcoma
EP300 2 / 14 Desmoplastic small round cell tumor, Solitary fibrous tumor
ERBB4 2 / 14 Solitary fibrous tumor, Synovial sarcoma
FBXW7 2 / 14 Soft tissue sarcoma, Solitary fibrous tumor
FEV 2 / 14 Clear cell sarcoma, Malignant soft tissue neoplasm
FGFR3 2 / 14 Soft tissue sarcoma, Solitary fibrous tumor
HGF 2 / 14 Dermatofibrosarcoma protuberans, Synovial sarcoma
HLA-A 2 / 14 Neurofibroma, Soft tissue sarcoma
HRAS 2 / 14 Soft tissue sarcoma, Synovial sarcoma
JAK2 2 / 14 Desmoplastic small round cell tumor, Malignant soft tissue neoplasm
KDM6A 2 / 14 Soft tissue sarcoma, Spindle cell rhabdomyosarcoma
KMT2A 2 / 14 Soft tissue sarcoma, Synovial sarcoma
MYOD1 2 / 14 Myopathy, congenital, with diaphragmatic defects, respiratory insufficiency, and dysmorphic facies, Spindle cell rhabdomyosarcoma
NF2 2 / 14 Malignant peripheral nerve sheath tumor, Neurofibroma
NR4A3 2 / 14 Clear cell sarcoma, Extraskeletal myxoid chondrosarcoma
PALB2 2 / 14 Soft tissue sarcoma, Synovial sarcoma
PDGFRA 2 / 14 Malignant peripheral nerve sheath tumor, Synovial sarcoma
RASA1 2 / 14 Desmoplastic small round cell tumor, Synovial sarcoma
SF3B1 2 / 14 Extraskeletal myxoid chondrosarcoma, Synovial sarcoma
SPEN 2 / 14 Soft tissue sarcoma, Solitary fibrous tumor
STAG2 2 / 14 Desmoplastic small round cell tumor, Malignant peripheral nerve sheath tumor
TERT 2 / 14 Lipoma, Soft tissue sarcoma
USP6 2 / 14 Malignant peripheral nerve sheath tumor, Synovial sarcoma
What do these columns mean?
Connections in cluster
How many other members this disease has a shared-gene link to (the node size in the network above). The most-connected diseases are the cluster's core.
Significant partners
How many of those links are statistically significant (FDR q < 0.05).
Curated genes
Distinct curated genes linked to that disease in GeDiPNet.
Member diseases (Top shared genes)
How many of this cluster's diseases are linked to the gene, out of the cluster's total. Genes shared by many members are the most direct explanation of why they group together.
Overlap genes (x / y)
x = genes shared between this cluster and the pathway/GO term; y = that pathway/GO term's total gene count. A higher x relative to y (and to the cluster's own size) means a tighter biological match.
Cluster gene count
Total distinct genes across every disease in this cluster -- the "n" used in the significance test below.
Fold enrichment
Observed overlap divided by the overlap expected by chance, given the cluster's gene count, the pathway/term's size and the gene universe tested. 5× means five times more shared genes than random. Tells strong hits apart when q-values are all vanishingly small.
P-value / FDR q-value
Is this pathway/GO term's overlap with the cluster more than chance? Upper-tail hypergeometric test, Benjamini-Hochberg corrected across every tested pathway/term (prefer the q-value -- it accounts for testing many at once).
Shared genes (Pairs within this cluster)
Number of curated genes the two diseases in that row have in common.
Similarity score (Pairs within this cluster)
Jaccard-based gene overlap between the two specific diseases in that row -- same metric as the main Shared-Gene Disease Pairs page.

Enriched Pathways (why this cluster is grouped, biologically)

Pathway ⇵ Source ⇵ Overlap genes ⇵ Fold enrichment ⇵ P-value ⇵ FDR q-value ⇵
Transcriptional misregulation in cancer
EWSR1, WT1, NR4A3, TAF15, SS18, SSX1, SSX2, PAX3, KMT2A, H3-3B, DDIT3, TP53
 KEGG 36 / 198 11.3× 4.51e-28 1.13e-24 ✓ sig.
Prostate cancer
PDGFB, PTEN, CREB3L2, TP53, PIK3CA, MTOR, EP300, RAF1, FGFR1, CREB3L1, EGFR, FOXO1
 KEGG 28 / 98 17.8× 7.80e-28 1.88e-24 ✓ sig.
Pathways in cancer
PDGFB, TFG, PTEN, TERT, JAK2, HGF, ALK, PTCH1, TP53, FLT4, PIK3CA, MTOR
 KEGG 51 / 533 6.0× 4.95e-26 9.32e-23 ✓ sig.
PI3K-Akt signaling pathway
COL1A1, PDGFB, PTEN, JAK2, YWHAE, HGF, KDR, CREB3L2, BRCA1, TP53, FLT4, PIK3CA
 KEGG 39 / 361 6.7× 9.83e-22 9.98e-19 ✓ sig.
EGFR tyrosine kinase inhibitor resistance
PDGFB, PTEN, JAK2, HGF, KDR, PIK3CA, MTOR, RAF1, EGFR, HRAS, FGFR2, BRAF
 KEGG 22 / 80 17.1× 1.22e-21 1.22e-18 ✓ sig.
Central carbon metabolism in cancer
PTEN, NTRK3, TP53, IDH2, PIK3CA, MTOR, RAF1, FGFR1, EGFR, HRAS, FGFR2, IDH1
 KEGG 21 / 71 18.4× 1.91e-21 1.83e-18 ✓ sig.
Gastric cancer
TERT, HGF, TP53, PIK3CA, MTOR, RAF1, EGFR, HRAS, TGFBR2, CTNNB1, APC, FGFR2
 KEGG 26 / 150 10.8× 7.00e-20 5.09e-17 ✓ sig.
Melanoma
PDGFB, PTEN, HGF, TP53, PIK3CA, RAF1, FGFR1, EGFR, HRAS, CDH1, CCND1, CDKN2A
 KEGG 20 / 73 17.0× 9.97e-20 7.13e-17 ✓ sig.
Hepatocellular carcinoma
PTEN, TERT, ARID1A, HGF, TP53, PIK3CA, MTOR, RAF1, EGFR, ARID1B, SMARCA4, HRAS
 KEGG 27 / 170 9.9× 1.40e-19 9.82e-17 ✓ sig.
Endometrial cancer
PTEN, TP53, PIK3CA, RAF1, EGFR, HRAS, CTNNB1, APC, CDH1, CCND1, MLH1, BRAF
 KEGG 18 / 59 19.0× 8.35e-19 5.14e-16 ✓ sig.
Non-small cell lung cancer
HGF, ALK, TP53, PIK3CA, RAF1, EGFR, HRAS, CCND1, CDKN2A, BRAF, KRAS, NRAS
 KEGG 18 / 73 15.3× 5.83e-17 2.58e-14 ✓ sig.
Glioma
PDGFB, PTEN, TP53, PIK3CA, MTOR, RAF1, EGFR, HRAS, CCND1, CDKN2A, BRAF, KRAS
 KEGG 18 / 76 14.7× 1.27e-16 5.19e-14 ✓ sig.
Colorectal cancer
TP53, PIK3CA, MTOR, RAF1, EGFR, HRAS, TGFBR2, CTNNB1, APC, CCND1, MLH1, BRAF
 KEGG 18 / 87 12.9× 1.68e-15 5.58e-13 ✓ sig.
Breast cancer
PTEN, BRCA1, TP53, FLT4, PIK3CA, MTOR, RAF1, FGFR1, EGFR, HRAS, CTNNB1, APC
 KEGG 22 / 148 9.3× 1.69e-15 5.60e-13 ✓ sig.
MAPK signaling pathway
PDGFB, DAXX, HGF, KDR, DDIT3, TP53, FLT4, RAF1, FGFR1, EGFR, RASA1, HRAS
 KEGG 29 / 299 6.0× 4.89e-15 1.48e-12 ✓ sig.

Enriched GO Terms (Biological Process, a second line of biological evidence)

GO term ⇵ GO ID ⇵ Overlap genes ⇵ Fold enrichment ⇵ P-value ⇵ FDR q-value ⇵
positive regulation of transcription by RNA polymerase II
WT1, NR4A3, TCF12, PTEN, SS18, JAK2, MED12, TET2, NPM1, HGF, KMT2C, PAX3
 GO:0045944 67 / 1,208 5.4× 1.07e-31 7.02e-28 ✓ sig.
positive regulation of DNA-templated transcription
COL1A1, PDGFB, WT1, NR4A3, TAF15, TCF12, DAXX, MED12, ARID1A, NPM1, PAX3, KMT2A
 GO:0045893 52 / 778 6.5× 5.53e-28 2.50e-24 ✓ sig.
regulation of DNA-templated transcription
EWSR1, WT1, NR4A3, TAF15, SSX1, SSX2, DAXX, KMT2C, PAX3, KMT2A, CREB3L2, KDM5A
 GO:0006355 58 / 1,454 3.9× 5.72e-20 9.07e-17 ✓ sig.
negative regulation of transcription by RNA polymerase II
WT1, NR4A3, SSX1, SUZ12, KDM5A, CIC, DDIT3, PTCH1, TP53, ETV6, HMGA2, EP300
 GO:0000122 47 / 1,002 4.5× 8.14e-19 1.09e-15 ✓ sig.
positive regulation of cell population proliferation
PDGFB, PTEN, SS18, JAK2, NTRK3, SUZ12, NPM1, KDR, KMT2D, FLT4, MTOR, HMGA2
 GO:0008284 33 / 532 6.0× 9.08e-17 9.00e-14 ✓ sig.
chromatin organization
BAP1, JAK2, DAXX, SUZ12, ARID1A, TET2, KMT2C, KMT2A, KDM5A, KMT2D, HMGA2, BCOR
 GO:0006325 30 / 449 6.5× 3.57e-16 3.14e-13 ✓ sig.
chromatin remodeling
SS18, JAK2, DAXX, ARID1A, NPM1, KMT2C, BRCA1, KDM5A, EP300, SF3B1, PAX7, BCOR
 GO:0006338 26 / 320 7.9× 3.71e-16 3.24e-13 ✓ sig.
regulation of transcription by RNA polymerase II
WT1, NR4A3, TCF12, SS18, MED12, ARID1A, PAX3, CREB3L2, BRCA1, CIC, DDIT3, TP53
 GO:0006357 55 / 1,602 3.3× 5.44e-16 4.67e-13 ✓ sig.
cell surface receptor protein tyrosine kinase signaling pathway
PDGFB, NTRK3, KDR, ALK, FLT4, ROS1, EGFR, EPHA3, NTRK2, PDGFRA, ERBB4, RET
 GO:0007169 17 / 120 13.7× 6.37e-15 4.53e-12 ✓ sig.
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
PDGFB, JAK2, NTRK3, HGF, KDR, PIK3CA, MTOR, CBL, EP300, FGFR1, EGFR, GATA3
 GO:0051897 21 / 217 9.4× 9.50e-15 6.53e-12 ✓ sig.
negative regulation of cell population proliferation
WT1, BAP1, PTEN, JAK2, NPM1, PTCH1, TP53, NF2, RAF1, HRAS, GATA3, CTNNB1
 GO:0008285 28 / 444 6.1× 1.62e-14 1.07e-11 ✓ sig.
positive regulation of cell differentiation
JAK2, ARID1A, NF2, MTOR, FGFR1, TP63, ARID1B, SMARCA4, GATA3, CTNNB1, SMARCB1, ARID2
 GO:0045597 14 / 83 16.3× 1.39e-13 7.76e-11 ✓ sig.
peptidyl-tyrosine phosphorylation
PDGFB, KDR, FLT4, FGFR1, EPHA3, FGFR2, PDGFRA, ERBB4, PTPN6, FLT3, CSF1R
 GO:0018108 11 / 39 27.3× 1.40e-13 7.80e-11 ✓ sig.
regulation of cell population proliferation
NPM1, ALK, PTCH1, TP53, NF2, EGFR, PRDM1, FOXO1, HRAS, TGFBR2, CTNNB1, ABL1
 GO:0042127 19 / 201 9.2× 2.90e-13 1.53e-10 ✓ sig.
positive regulation of MAPK cascade
PDGFB, JAK2, NTRK3, HGF, KDR, FLT4, RAF1, FGFR1, EGFR, HRAS, CTNNB1, NTRK2
 GO:0043410 19 / 224 8.2× 2.03e-12 9.11e-10 ✓ sig.

Pairs within this cluster, by significance

Disease A ⇵ Disease B ⇵ Similarity score ⇵ Shared genes ⇵ P-value ⇵ FDR q-value ⇵
Malignant peripheral nerve sheath tumor Synovial sarcoma 0.301 28 1.21e-55 3.46e-54 ✓ sig.
Soft tissue sarcoma Synovial sarcoma 0.273 30 7.60e-55 2.16e-53 ✓ sig.
Clear cell sarcoma Soft tissue sarcoma 0.247 18 2.23e-39 5.18e-38 ✓ sig.
Malignant peripheral nerve sheath tumor Soft tissue sarcoma 0.226 21 5.51e-39 1.27e-37 ✓ sig.
Clear cell sarcoma Synovial sarcoma 0.225 18 1.78e-38 4.09e-37 ✓ sig.
Malignant soft tissue neoplasm Soft tissue sarcoma 0.227 17 5.61e-36 1.24e-34 ✓ sig.
Clear cell sarcoma Malignant soft tissue neoplasm 0.389 14 1.67e-35 3.64e-34 ✓ sig.
Malignant soft tissue neoplasm Synovial sarcoma 0.207 17 3.93e-35 8.53e-34 ✓ sig.
Clear cell sarcoma Desmoplastic small round cell tumor 0.289 13 2.99e-30 5.90e-29 ✓ sig.
Malignant peripheral nerve sheath tumor Neurofibroma 0.241 13 8.00e-30 1.57e-28 ✓ sig.
Dermatofibrosarcoma protuberans Malignant peripheral nerve sheath tumor 0.241 13 8.00e-30 1.57e-28 ✓ sig.
Desmoplastic small round cell tumor Synovial sarcoma 0.176 16 1.12e-29 2.18e-28 ✓ sig.
Desmoplastic small round cell tumor Soft tissue sarcoma 0.176 15 4.90e-28 9.20e-27 ✓ sig.
Soft tissue sarcoma Solitary fibrous tumor 0.176 15 4.90e-28 9.20e-27 ✓ sig.
Malignant peripheral nerve sheath tumor Solitary fibrous tumor 0.209 14 5.17e-28 9.70e-27 ✓ sig.
Clear cell sarcoma Malignant peripheral nerve sheath tumor 0.220 13 7.28e-28 1.36e-26 ✓ sig.
Solitary fibrous tumor Synovial sarcoma 0.163 15 2.63e-27 4.84e-26 ✓ sig.
Desmoplastic small round cell tumor Malignant soft tissue neoplasm 0.255 12 4.58e-27 8.39e-26 ✓ sig.
Extraskeletal myxoid chondrosarcoma Malignant peripheral nerve sheath tumor 0.188 12 3.88e-24 6.46e-23 ✓ sig.
Dermatofibrosarcoma protuberans Neurofibroma 0.300 9 6.02e-23 9.62e-22 ✓ sig.
Extraskeletal myxoid chondrosarcoma Malignant soft tissue neoplasm 0.227 10 1.93e-22 3.06e-21 ✓ sig.
Extraskeletal myxoid chondrosarcoma Neurofibroma 0.231 9 4.48e-21 6.78e-20 ✓ sig.
Dermatofibrosarcoma protuberans Solitary fibrous tumor 0.205 9 2.49e-20 3.69e-19 ✓ sig.
Neurofibroma Solitary fibrous tumor 0.178 8 1.26e-17 1.70e-16 ✓ sig.
Extraskeletal myxoid chondrosarcoma Lipoma 0.174 8 4.02e-17 5.32e-16 ✓ sig.
Lipoma Malignant soft tissue neoplasm 0.159 7 5.36e-15 6.47e-14 ✓ sig.
Desmoplastic small round cell tumor Spindle cell rhabdomyosarcoma 0.125 5 1.46e-11 1.47e-10 ✓ sig.
Clear cell sarcoma Spindle cell rhabdomyosarcoma 0.125 4 1.45e-9 1.24e-8 ✓ sig.
Myopathy, congenital, with diaphragmatic defects, respiratory insufficiency, and dysmorphic facies Spindle cell rhabdomyosarcoma 0.083 1 7.10e-4 1.17e-3 ✓ sig.
Lipoma Uterine benign neoplasm 0.038 1 1.61e-3 2.26e-3 ✓ sig.