Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
BIPOLAR DISORDER	MONDO_0004985 C0005586 MESH:D001714	INSYN2B	Unknown	33169155 34002096	GWAS catalog	—
		IQCH	Unknown	31043756 38154582	GWAS catalog	—
		IRAG1	Unknown	20889312	GWAS catalog	cGMP-PKG signaling pathway Vascular smooth muscle contraction cGMP effects
		ITGA9	Unknown	—	Disgenet	PI3K-Akt signaling pathway Focal adhesion ECM-receptor interaction +10 more
		ITGAM	Unknown	—	Disgenet	Rap1 signaling pathway Phagosome Cell adhesion molecules +18 more
		ITIH1	Unknown	19416921 24166486 28072414 31043756 32606422 33263727 34159505	CTD, Disgenet, GWAS catalog	—
		ITIH3	Unknown	21926972 23453885 30626913 31835028 33479212	Disgenet, GWAS catalog	Platelet degranulation
		ITIH4	Unknown	31043756	Disgenet, GWAS catalog	Platelet degranulation
		ITPR1	Unknown	—	Disgenet	Calcium signaling pathway cGMP-PKG signaling pathway Phosphatidylinositol signaling system +53 more
		JADE2	Unknown	31043756 32606422	GWAS catalog	HATs acetylate histones
		JPH3	Unknown	24322204	GWAS catalog	—
		KAT2B	Unknown	20889312	GWAS catalog	Viral life cycle - HIV-1 Notch signaling pathway Thyroid hormone signaling pathway +17 more
		KAT6B	Unknown	—	Disgenet	HATs acetylate histones
		KCNB1	Unknown	31835028 32606422 34002096	GWAS catalog	Voltage gated Potassium channels Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
		KCNG1	Unknown	31043756 31754094 33169155	GWAS catalog	Voltage gated Potassium channels
		KCNG2	Unknown	33479212	GWAS catalog	Voltage gated Potassium channels Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
		KCNK13	Unknown	30217971	GWAS catalog	Tandem pore domain halothane-inhibited K+ channel (THIK) Phase 4 - resting membrane potential
		KCNK9	Unknown	33893285	GWAS catalog	Aldosterone synthesis and secretion TWIK-releated acid-sensitive K+ channel (TASK) Phase 4 - resting membrane potential
		KCNMB2	Unknown	22688191	GWAS catalog	cGMP-PKG signaling pathway Vascular smooth muscle contraction Insulin secretion +1 more
		KCNN2	Unknown	31043756	GWAS catalog	Serotonergic synapse Insulin secretion GnRH secretion +2 more
		KCNN3	Unknown	31043756	Disgenet, GWAS catalog	Insulin secretion GnRH secretion Ca2+ activated K+ channels
		KCNQ2	Unknown	—	Disgenet	Cholinergic synapse Voltage gated Potassium channels
		KCNQ3	Unknown	—	Disgenet	Cholinergic synapse Voltage gated Potassium channels
		KCNS1	Unknown	22925353	GWAS catalog	Voltage gated Potassium channels
		KCNU1	Unknown	21254220	GWAS catalog	cGMP-PKG signaling pathway Vascular smooth muscle contraction Insulin secretion +1 more
		KCTD12	Unknown	—	Disgenet	—
		KCTD2	Unknown	31043756	GWAS catalog	—
		KDM2B	Unknown	31926635	GWAS catalog	Polycomb repressive complex HDMs demethylate histones
		KDM3B	Unknown	31043756 31835028 32606422 34002096	GWAS catalog	Thermogenesis HDMs demethylate histones
		KDM4A	Unknown	33479212	GWAS catalog	HDMs demethylate histones Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
		KDM4C	Unknown	20889312	GWAS catalog	HDMs demethylate histones Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
		KIF15	Unknown	31043756	GWAS catalog	Motor proteins MHC class II antigen presentation COPI-dependent Golgi-to-ER retrograde traffic +1 more
		KIF18A	Unknown	21254220	GWAS catalog	Motor proteins Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal MHC class II antigen presentation +7 more
		KIF21B	Unknown	23453885	GWAS catalog	Motor proteins COPI-dependent Golgi-to-ER retrograde traffic Kinesins
		KIF5B	Unknown	23092984	GWAS catalog	Endocytosis Dopaminergic synapse Motor proteins +12 more
		KIF5C	Unknown	23453885	GWAS catalog	Endocytosis Dopaminergic synapse Motor proteins +8 more
		KIT	Unknown	19416921	GWAS catalog	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +15 more
		KIZ	Unknown	31835028 33479212	GWAS catalog	—
		KLC1	Unknown	33479212 34159505	GWAS catalog	Motor proteins Alzheimer disease Parkinson disease +9 more
		KLF16	Unknown	33686288	GWAS catalog	—
		KLF9	Unknown	34099189	GWAS catalog	—
		KLK8	Unknown	—	Disgenet	Formation of the cornified envelope
		KMT2A	Unknown	23453885	GWAS catalog	Lysine degradation Metabolic pathways Cushing syndrome +4 more
		KMT2D	Unknown	28115744	GWAS catalog	Lysine degradation Metabolic pathways Cushing syndrome +4 more
		KPNA4	Unknown	31043756	GWAS catalog	Nucleocytoplasmic transport Salmonella infection Chemical carcinogenesis - receptor activation +2 more
		KRTAP4-7	Unknown	20889312	GWAS catalog	—
		KRTAP4-8	Unknown	20889312	GWAS catalog	Keratinization
		KRTDAP	Unknown	22925353	GWAS catalog	—
		L3MBTL2	Unknown	31835028 31926635	GWAS catalog	Polycomb repressive complex SUMOylation of chromatin organization proteins Transcriptional Regulation by E2F6
		LAMP3	Unknown	17554300 21254220 26503763	GWAS catalog	Lysosome
BIPOLAR I DISORDER	EFO_0009963 C0853193	ITIH4	Unknown	31043756	GWAS catalog	Platelet degranulation
		KAT6B	Unknown	—	Disgenet	HATs acetylate histones
		KCNB1	Unknown	34002096	GWAS catalog	Voltage gated Potassium channels Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
		KCNG1	Unknown	31043756	GWAS catalog	Voltage gated Potassium channels
		KDM3B	Unknown	31043756 34002096	GWAS catalog	Thermogenesis HDMs demethylate histones
BIPOLAR I DISORDER, MOST RECENT EPISODE MANIC	C0024713	ITIH1	Unknown	—	Disgenet	—
BIPOLAR I DISORDER, MOST RECENT EPISODE MANIC	C0024713	KAT6B	Unknown	—	Disgenet	HATs acetylate histones
MIXED BIPOLAR I DISORDER	C0236780	ITIH1	Unknown	—	Disgenet	—
MIXED BIPOLAR I DISORDER	C0236780	KAT6B	Unknown	—	Disgenet	HATs acetylate histones

«‹1…10 111213 14…25 ›»

Bipolar disorder

Bookmark This Disease