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Gene Gene information from NCBI Gene database.
Entrez ID 140735
Gene name Dynein light chain LC8-type 2
Gene symbol DYNLL2
Synonyms (NCBI Gene)
DNCL1BDlc2RSPH22
Chromosome 17
Chromosome location 17q22
miRNA miRNA information provided by mirtarbase database.
867 Show/Hide all (867)
miRTarBase ID miRNA Experiments Reference
MIRT020140 hsa-miR-130b-3p Sequencing 20371350
MIRT025997 hsa-miR-148a-3p Sequencing 20371350
MIRT031095 hsa-miR-19b-3p Sequencing 20371350
MIRT558260 hsa-miR-888-3p HITS-CLIP 19536157
MIRT708327 hsa-miR-181a-2-3p HITS-CLIP 19536157
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
32 Show/Hide all (32)
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 16189514, 20921139, 22458338, 25416956, 27173435, 30649997, 31515488, 32296183, 32707033, 33961781, 35271311
GO:0005634 Component Nucleus HDA 21630459
GO:0005737 Component Cytoplasm IEA
GO:0005813 Component Centrosome IDA 21399614
GO:0005829 Component Cytosol TAS
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
608942 24596 ENSG00000264364
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q96FJ2
Protein name Dynein light chain 2, cytoplasmic (8 kDa dynein light chain b) (DLC8b) (Dynein light chain LC8-type 2)
Protein function Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor
PDB 2XQQ , 3P8M , 4D07 , 7CNU
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01221 Dynein_light 5 → 88 Dynein light chain type 1 Domain
Sequence
Sequence length 89
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
KEGG Pathway Reactome Pathway
Motor proteins Activation of BMF and translocation to mitochondria
Vasopressin-regulated water reabsorption Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Salmonella infection Macroautophagy
  MHC class II antigen presentation
  Separation of Sister Chromatids
  Resolution of Sister Chromatid Cohesion
  HSP90 chaperone cycle for steroid hormone receptors (SHR)
  Intraflagellar transport
  RHO GTPases Activate Formins
  COPI-mediated anterograde transport
  COPI-independent Golgi-to-ER retrograde traffic
  Mitotic Prometaphase
  HCMV Early Events
  Aggrephagy
  EML4 and NUDC in mitotic spindle formation