The protein encoded by this gene belongs to light intermediate subunit family, whose members are components of the multiprotein cytoplasmic dynein complex, which is involved in intracellular trafficking and chromosome segregation during mitosis. The prote
miRNAmiRNA information provided by mirtarbase database.
Gene ontology (GO)Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor
["Phagosome","Motor proteins","Vasopressin-regulated water reabsorption","Salmonella infection","Aggrephagy","COPI-mediated anterograde transport","Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal","Separation of Sister Chromatids","Resolution of Sister Chromatid Cohesion","RHO GTPases Activate Formins","Mitotic Prometaphase","EML4 and NUDC in mitotic spindle formation"]
["Phagosome","Motor proteins","Vasopressin-regulated water reabsorption","Salmonella infection","Aggrephagy","COPI-mediated anterograde transport","Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal","Separation of Sister Chromatids","Resolution of Sister Chromatid Cohesion","RHO GTPases Activate Formins","Mitotic Prometaphase","EML4 and NUDC in mitotic spindle formation"]
["Motor proteins","Vasopressin-regulated water reabsorption","Salmonella infection","Aggrephagy","COPI-mediated anterograde transport","Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal","Separation of Sister Chromatids","Resolution of Sister Chromatid Cohesion","RHO GTPases Activate Formins","Mitotic Prometaphase","EML4 and NUDC in mitotic spindle formation","MHC class II antigen presentation"]
["Phagosome","Motor proteins","Vasopressin-regulated water reabsorption","Salmonella infection","Aggrephagy","COPI-mediated anterograde transport","Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal","Separation of Sister Chromatids","Resolution of Sister Chromatid Cohesion","RHO GTPases Activate Formins","Mitotic Prometaphase","EML4 and NUDC in mitotic spindle formation"]
["Phagosome","Motor proteins","Vasopressin-regulated water reabsorption","Salmonella infection","Aggrephagy","COPI-mediated anterograde transport","Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal","Separation of Sister Chromatids","Resolution of Sister Chromatid Cohesion","RHO GTPases Activate Formins","Mitotic Prometaphase","EML4 and NUDC in mitotic spindle formation"]
0
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Diseases Linked via Similar GenesDiseases curated for genes most similar to DYNC1LI1 (see Related Genes above), that are NOT already directly curated for DYNC1LI1 itself -- a lead worth checking, not a confirmed association.