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Gene Gene information from NCBI Gene database.
Entrez ID 51143
Gene name Dynein cytoplasmic 1 light intermediate chain 1
Gene symbol DYNC1LI1
Synonyms (NCBI Gene)
DLC-ADLIC-1DNCLI1LIC1
Chromosome 3
Chromosome location 3p22.3
Summary The protein encoded by this gene belongs to light intermediate subunit family, whose members are components of the multiprotein cytoplasmic dynein complex, which is involved in intracellular trafficking and chromosome segregation during mitosis. The prote
miRNA miRNA information provided by mirtarbase database.
328 Show/Hide all (328)
miRTarBase ID miRNA Experiments Reference
MIRT023640 hsa-miR-1-3p Proteomics 18668040
MIRT028455 hsa-miR-30a-5p Proteomics 18668040
MIRT028455 hsa-miR-30a-5p CLASH 23622248
MIRT631985 hsa-miR-6776-3p HITS-CLIP 23313552
MIRT608437 hsa-miR-8485 HITS-CLIP 23313552
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
43 Show/Hide all (43)
GO ID Ontology Definition Evidence Reference
GO:0000166 Function Nucleotide binding IEA
GO:0000226 Process Microtubule cytoskeleton organization IBA
GO:0000775 Component Chromosome, centromeric region IEA
GO:0000776 Component Kinetochore IDA 19229290
GO:0000776 Component Kinetochore IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
615890 18745 ENSG00000144635
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9Y6G9
Protein name Cytoplasmic dynein 1 light intermediate chain 1 (LIC1) (Dynein light chain A) (DLC-A) (Dynein light intermediate chain 1, cytosolic) (DLIC-1)
Protein function Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor
PDB 6B9H , 6PSD , 6PSE
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF05783 DLIC 43 → 519 Dynein light intermediate chain (DLIC) Family
Sequence
Sequence length 523
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
KEGG Pathway Reactome Pathway
Phagosome Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Motor proteins MHC class II antigen presentation
Vasopressin-regulated water reabsorption Separation of Sister Chromatids
Salmonella infection Resolution of Sister Chromatid Cohesion
  HSP90 chaperone cycle for steroid hormone receptors (SHR)
  RHO GTPases Activate Formins
  Neutrophil degranulation
  COPI-mediated anterograde transport
  COPI-independent Golgi-to-ER retrograde traffic
  Mitotic Prometaphase
  HCMV Early Events
  Aggrephagy
  EML4 and NUDC in mitotic spindle formation