Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
BIPOLAR DISORDER	MONDO_0004985 C0005586 MESH:D001714	NBAS	Unknown	34099189	GWAS catalog	COPI-dependent Golgi-to-ER retrograde traffic
		NCAM1	Unknown	—	Disgenet	Virion - Ebolavirus, Lyssavirus and Morbillivirus Cell adhesion molecules Prion disease +5 more
		NCAN	Unknown	21353194 31043756 32606422 33263727 33686288 34002096 38154582	CTD, Disgenet, GWAS catalog	A tetrasaccharide linker sequence is required for GAG synthesis Chondroitin sulfate biosynthesis Dermatan sulfate biosynthesis +8 more
		NCBP3	Unknown	34099189	GWAS catalog	—
		NCKAP5	Unknown	20889312	GWAS catalog	—
		NCMAP	Unknown	34099189	GWAS catalog	—
		NCOA5	Unknown	33479212	GWAS catalog	—
		NCS1	Unknown	—	Disgenet	—
		ND1	Unknown	—	Disgenet	Oxidative phosphorylation Metabolic pathways Thermogenesis +11 more
		NDST3	Unknown	—	Disgenet	Glycosaminoglycan biosynthesis - heparan sulfate / heparin Metabolic pathways HS-GAG biosynthesis
		NDUFAF7	Unknown	38154582	GWAS catalog	Thermogenesis Complex I biogenesis
		NDUFV1	Unknown	—	Disgenet	Oxidative phosphorylation Metabolic pathways Thermogenesis +12 more
		NDUFV2	Unknown	19135101	CTD, Disgenet	Oxidative phosphorylation Metabolic pathways Thermogenesis +12 more
		NDUFV3	Unknown	—	Disgenet	Oxidative phosphorylation Metabolic pathways Thermogenesis +12 more
		NEDD4	Unknown	—	Disgenet	Ubiquitin mediated proteolysis Endocytosis Tight junction +6 more
		NEFL	Unknown	—	Disgenet	Amyotrophic lateral sclerosis Pathways of neurodegeneration - multiple diseases Unblocking of NMDA receptors, glutamate binding and activation +1 more
		NEFM	Unknown	—	Disgenet	Amyotrophic lateral sclerosis Pathways of neurodegeneration - multiple diseases
		NEGR1	Unknown	31754094	GWAS catalog	Cell adhesion molecules Post-translational modification: synthesis of GPI-anchored proteins
		NEK4	Unknown	—	Disgenet	—
		NEURL1	Unknown	23453885	GWAS catalog	Constitutive Signaling by NOTCH1 PEST Domain Mutants Constitutive Signaling by NOTCH1 HD Domain Mutants Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
		NFAM1	Unknown	31926635	GWAS catalog	Neutrophil degranulation
		NFIA	Unknown	22925353	GWAS catalog	—
		NFIL3	Unknown	25781172	GWAS catalog	Circadian rhythm
		NFIX	Unknown	28115744	Disgenet, GWAS catalog	—
		NGEF	Unknown	31043756 31835028 32606422 33479212 34159505	GWAS catalog	Axon guidance NRAGE signals death through JNK Rho GTPase cycle +2 more
		NGF	Unknown	20889312	Disgenet, GWAS catalog	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +18 more
		NGFR	Unknown	19416921	GWAS catalog	Virion - Ebolavirus, Lyssavirus and Morbillivirus MAPK signaling pathway Ras signaling pathway +14 more
		NKAIN2	Unknown	34099189	GWAS catalog	—
		NLGN1	Unknown	27890468	Disgenet, GWAS catalog	Cell adhesion molecules Neurexins and neuroligins
		NLRC5	Unknown	22688191	GWAS catalog	DDX58/IFIH1-mediated induction of interferon-alpha/beta Negative regulators of DDX58/IFIH1 signaling
		NNMT	Unknown	—	Disgenet	Nicotinate and nicotinamide metabolism Metabolic pathways Methylation +1 more
		NOD2	Unknown	—	Disgenet	NOD-like receptor signaling pathway TNF signaling pathway Tuberculosis +7 more
		NOL4	Unknown	31926635	GWAS catalog	—
		NOS3	Unknown	—	Disgenet	Arginine biosynthesis Arginine and proline metabolism Metabolic pathways +24 more
		NOTCH4	Unknown	38154582	Disgenet, GWAS catalog	Endocrine resistance Notch signaling pathway Thyroid hormone signaling pathway +11 more
		NPAS2	Unknown	—	Disgenet	Circadian rhythm BMAL1:CLOCK,NPAS2 activates circadian gene expression PPARA activates gene expression +1 more
		NPAS3	Unknown	18711365 20713499 31043756 31835028	Disgenet, GWAS catalog	—
		NPTX1	Unknown	31043756	GWAS catalog	—
		NR1D1	Unknown	—	Disgenet	Circadian rhythm PPARA activates gene expression Transcriptional activation of mitochondrial biogenesis +2 more
		NR2E1	Unknown	—	Disgenet	Nuclear Receptor transcription pathway
		NR3C1	Unknown	14708030	CTD, Disgenet	Neuroactive ligand-receptor interaction HSP90 chaperone cycle for steroid hormone receptors (SHR) Nuclear Receptor transcription pathway +2 more
		NR4A2	Unknown	—	Disgenet	Aldosterone synthesis and secretion Parathyroid hormone synthesis, secretion and action Nuclear Receptor transcription pathway
		NREP	Unknown	20889312	GWAS catalog	—
		NRF1	Unknown	31043756	GWAS catalog	Apelin signaling pathway Huntington disease PPARA activates gene expression +1 more
		NRG1	Unknown	—	Disgenet	EGFR tyrosine kinase inhibitor resistance ErbB signaling pathway Amyotrophic lateral sclerosis +18 more
		NRG3	Unknown	26433762	Disgenet, GWAS catalog	ErbB signaling pathway Amyotrophic lateral sclerosis Signaling by ERBB2 +15 more
		NRGN	Unknown	31835028	Disgenet, GWAS catalog	Long-term potentiation
		NRXN1	Unknown	—	Disgenet	Cell adhesion molecules Neurexins and neuroligins
		NSUN4	Unknown	34099189	GWAS catalog	rRNA modification in the mitochondrion
		NT5C2	Unknown	23453885 31835028 33479212	GWAS catalog	Purine metabolism Pyrimidine metabolism Nicotinate and nicotinamide metabolism +4 more
BIPOLAR I DISORDER	EFO_0009963 C0853193	NCAN	Unknown	31043756 34002096	GWAS catalog	A tetrasaccharide linker sequence is required for GAG synthesis Chondroitin sulfate biosynthesis Dermatan sulfate biosynthesis +8 more
BIPOLAR I DISORDER	EFO_0009963 C0853193	NR2E1	Unknown	—	Disgenet	Nuclear Receptor transcription pathway
BIPOLAR I DISORDER, MOST RECENT EPISODE MANIC	C0024713	NCAM1	Unknown	—	Disgenet	Virion - Ebolavirus, Lyssavirus and Morbillivirus Cell adhesion molecules Prion disease +5 more
		NCAN	Unknown	—	Disgenet	A tetrasaccharide linker sequence is required for GAG synthesis Chondroitin sulfate biosynthesis Dermatan sulfate biosynthesis +8 more
		ND1	Unknown	—	Disgenet	Oxidative phosphorylation Metabolic pathways Thermogenesis +11 more
		NDUFV2	Unknown	—	Disgenet	Oxidative phosphorylation Metabolic pathways Thermogenesis +12 more
		NGF	Unknown	—	Disgenet	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +18 more
		NR3C1	Unknown	—	Disgenet	Neuroactive ligand-receptor interaction HSP90 chaperone cycle for steroid hormone receptors (SHR) Nuclear Receptor transcription pathway +2 more
		NRG1	Unknown	—	Disgenet	EGFR tyrosine kinase inhibitor resistance ErbB signaling pathway Amyotrophic lateral sclerosis +18 more
BIPOLAR II DISORDER	EFO_0009964	NCAN	Unknown	31043756	GWAS catalog	A tetrasaccharide linker sequence is required for GAG synthesis Chondroitin sulfate biosynthesis Dermatan sulfate biosynthesis +8 more
MIXED BIPOLAR I DISORDER	C0236780	NCAM1	Unknown	—	Disgenet	Virion - Ebolavirus, Lyssavirus and Morbillivirus Cell adhesion molecules Prion disease +5 more
		NCAN	Unknown	—	Disgenet	A tetrasaccharide linker sequence is required for GAG synthesis Chondroitin sulfate biosynthesis Dermatan sulfate biosynthesis +8 more
		ND1	Unknown	—	Disgenet	Oxidative phosphorylation Metabolic pathways Thermogenesis +11 more
		NDUFV2	Unknown	—	Disgenet	Oxidative phosphorylation Metabolic pathways Thermogenesis +12 more
		NGF	Unknown	—	Disgenet	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +18 more
		NR3C1	Unknown	—	Disgenet	Neuroactive ligand-receptor interaction HSP90 chaperone cycle for steroid hormone receptors (SHR) Nuclear Receptor transcription pathway +2 more
		NRG1	Unknown	—	Disgenet	EGFR tyrosine kinase inhibitor resistance ErbB signaling pathway Amyotrophic lateral sclerosis +18 more

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