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Gene Gene information from NCBI Gene database.
Entrez ID 55588
Gene name Mediator complex subunit 29
Gene symbol MED29
Synonyms (NCBI Gene)
IXLMED2
Chromosome 19
Chromosome location 19q13.2
Summary MED29 is a subunit of the Mediator complex, a multiprotein coactivator of RNA transcription that interacts with DNA-bound transcriptional activators, RNA polymerase II (see MIM 180660), and general initiation factors (Sato et al., 2003 [PubMed 14576168]).
miRNA miRNA information provided by mirtarbase database.
606 Show/Hide all (606)
miRTarBase ID miRNA Experiments Reference
MIRT036688 hsa-miR-935 CLASH 23622248
MIRT036114 hsa-miR-1296-5p CLASH 23622248
MIRT707080 hsa-miR-4524b-3p HITS-CLIP 21572407
MIRT707079 hsa-miR-1182 HITS-CLIP 21572407
MIRT707078 hsa-miR-6812-3p HITS-CLIP 21572407
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
14 Show/Hide all (14)
GO ID Ontology Definition Evidence Reference
GO:0003712 Function Transcription coregulator activity IBA
GO:0005515 Function Protein binding IPI 14576168, 14638676, 15175163, 21729782, 24882805, 25281560, 28514442, 32296183, 33961781, 35271311, 35512704
GO:0005634 Component Nucleus IDA 24882805
GO:0005634 Component Nucleus IEA
GO:0005654 Component Nucleoplasm IDA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
612914 23074 ENSG00000063322
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9NX70
Protein name Mediator of RNA polymerase II transcription subunit 29 (Intersex-like protein) (Mediator complex subunit 29)
Protein function Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RN
PDB 7EMF , 7ENA , 7ENC , 7ENJ , 7LBM , 8GXQ , 8GXS , 8T9D , 8TQW , 8TRH
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF11568 Med29 52 → 187 Mediator complex subunit 29 Family
Tissue specificity TISSUE SPECIFICITY: Widely expressed in embryo and adult. {ECO:0000269|PubMed:15555573}.
Sequence
Sequence length 200
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Reactome Pathway
PPARA activates gene expression
Transcriptional regulation of white adipocyte differentiation