MED6 (mediator complex subunit 6)

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Gene miRNA Gene ontology Other IDs Protein Pathways Related genes Diseases linked via similar genes

Gene

• Entrez ID: 10001
• Gene name: Mediator complex subunit 6
• Gene symbol: MED6
• Synonyms (NCBI Gene): ARC33, NY-REN-28
• Chromosome: 14
• Chromosome location: 14q24.2

miRNA Show/Hide all (324)

miRTarBase ID	miRNA	Experiments	Reference
MIRT004393	hsa-miR-199a-5p	Microarray, Northern blot	16331254
MIRT000781	hsa-miR-199a-3p	Microarray, Northern blot	16331254
MIRT027503	hsa-miR-98-5p	Microarray	19088304
MIRT1141769	hsa-let-7a	CLIP-seq
MIRT1141770	hsa-let-7b	CLIP-seq
MIRT1141771	hsa-let-7c	CLIP-seq
MIRT1141772	hsa-let-7d	CLIP-seq
MIRT1141773	hsa-let-7e	CLIP-seq
MIRT1141774	hsa-let-7f	CLIP-seq
MIRT1141775	hsa-let-7g	CLIP-seq
MIRT1141776	hsa-let-7i	CLIP-seq
MIRT1141777	hsa-miR-101	CLIP-seq
MIRT1141778	hsa-miR-106a	CLIP-seq
MIRT1141779	hsa-miR-106b	CLIP-seq
MIRT1141780	hsa-miR-1266	CLIP-seq
MIRT1141781	hsa-miR-1278	CLIP-seq
MIRT1141782	hsa-miR-1279	CLIP-seq
MIRT1141783	hsa-miR-17	CLIP-seq
MIRT1141784	hsa-miR-197	CLIP-seq
MIRT1141785	hsa-miR-198	CLIP-seq
MIRT1141786	hsa-miR-202	CLIP-seq
MIRT1141787	hsa-miR-20a	CLIP-seq
MIRT1141788	hsa-miR-20b	CLIP-seq
MIRT1141789	hsa-miR-2355-3p	CLIP-seq
MIRT1141790	hsa-miR-302a	CLIP-seq
MIRT1141791	hsa-miR-302b	CLIP-seq
MIRT1141792	hsa-miR-302c	CLIP-seq
MIRT1141793	hsa-miR-302d	CLIP-seq
MIRT1141794	hsa-miR-302e	CLIP-seq
MIRT1141795	hsa-miR-30a	CLIP-seq
MIRT1141796	hsa-miR-30b	CLIP-seq
MIRT1141797	hsa-miR-30c	CLIP-seq
MIRT1141798	hsa-miR-30d	CLIP-seq
MIRT1141799	hsa-miR-30e	CLIP-seq
MIRT1141800	hsa-miR-3125	CLIP-seq
MIRT1141801	hsa-miR-3127-5p	CLIP-seq
MIRT1141802	hsa-miR-3140-3p	CLIP-seq
MIRT1141803	hsa-miR-3150b-3p	CLIP-seq
MIRT1141804	hsa-miR-3155	CLIP-seq
MIRT1141805	hsa-miR-3155b	CLIP-seq
MIRT1141806	hsa-miR-330-3p	CLIP-seq
MIRT1141807	hsa-miR-335	CLIP-seq
MIRT1141808	hsa-miR-3607-5p	CLIP-seq
MIRT1141809	hsa-miR-3613-3p	CLIP-seq
MIRT1141810	hsa-miR-3617	CLIP-seq
MIRT1141811	hsa-miR-362-5p	CLIP-seq
MIRT1141812	hsa-miR-3659	CLIP-seq
MIRT1141813	hsa-miR-372	CLIP-seq
MIRT1141814	hsa-miR-373	CLIP-seq
MIRT1141815	hsa-miR-3916	CLIP-seq
MIRT1141816	hsa-miR-3918	CLIP-seq
MIRT1141817	hsa-miR-410	CLIP-seq
MIRT1141818	hsa-miR-4294	CLIP-seq
MIRT1141819	hsa-miR-433	CLIP-seq
MIRT1141820	hsa-miR-4421	CLIP-seq
MIRT1141821	hsa-miR-4438	CLIP-seq
MIRT1141822	hsa-miR-4457	CLIP-seq
MIRT1141823	hsa-miR-4458	CLIP-seq
MIRT1141824	hsa-miR-4497	CLIP-seq
MIRT1141825	hsa-miR-4500	CLIP-seq
MIRT1141826	hsa-miR-4518	CLIP-seq
MIRT1141827	hsa-miR-4645-5p	CLIP-seq
MIRT1141828	hsa-miR-4646-3p	CLIP-seq
MIRT1141829	hsa-miR-4658	CLIP-seq
MIRT1141830	hsa-miR-4673	CLIP-seq
MIRT1141831	hsa-miR-4689	CLIP-seq
MIRT1141832	hsa-miR-4712-5p	CLIP-seq
MIRT1141833	hsa-miR-4731-5p	CLIP-seq
MIRT1141834	hsa-miR-4740-3p	CLIP-seq
MIRT1141835	hsa-miR-4753-3p	CLIP-seq
MIRT1141836	hsa-miR-4784	CLIP-seq
MIRT1141837	hsa-miR-483-5p	CLIP-seq
MIRT1141838	hsa-miR-484	CLIP-seq
MIRT1141839	hsa-miR-495	CLIP-seq
MIRT1141840	hsa-miR-500b	CLIP-seq
MIRT1141841	hsa-miR-501-5p	CLIP-seq
MIRT1141842	hsa-miR-5095	CLIP-seq
MIRT1141843	hsa-miR-5096	CLIP-seq
MIRT1141844	hsa-miR-512-3p	CLIP-seq
MIRT1141845	hsa-miR-513b	CLIP-seq
MIRT1141846	hsa-miR-519d	CLIP-seq
MIRT1141847	hsa-miR-520a-3p	CLIP-seq
MIRT1141848	hsa-miR-520b	CLIP-seq
MIRT1141849	hsa-miR-520c-3p	CLIP-seq
MIRT1141850	hsa-miR-520d-3p	CLIP-seq
MIRT1141851	hsa-miR-520e	CLIP-seq
MIRT1141852	hsa-miR-520g	CLIP-seq
MIRT1141853	hsa-miR-520h	CLIP-seq
MIRT1141854	hsa-miR-574-5p	CLIP-seq
MIRT1141855	hsa-miR-607	CLIP-seq
MIRT1141856	hsa-miR-641	CLIP-seq
MIRT1141857	hsa-miR-770-5p	CLIP-seq
MIRT1141858	hsa-miR-889	CLIP-seq
MIRT1141859	hsa-miR-924	CLIP-seq
MIRT1141860	hsa-miR-93	CLIP-seq
MIRT1141861	hsa-miR-942	CLIP-seq
MIRT1141862	hsa-miR-98	CLIP-seq
MIRT1141782	hsa-miR-1279	CLIP-seq
MIRT1141784	hsa-miR-197	CLIP-seq
MIRT2040301	hsa-miR-3149	CLIP-seq
MIRT1141803	hsa-miR-3150b-3p	CLIP-seq
MIRT1141804	hsa-miR-3155	CLIP-seq
MIRT1141805	hsa-miR-3155b	CLIP-seq
MIRT2040302	hsa-miR-3545-3p	CLIP-seq
MIRT1141810	hsa-miR-3617	CLIP-seq
MIRT2040303	hsa-miR-3663-5p	CLIP-seq
MIRT1141817	hsa-miR-410	CLIP-seq
MIRT2040304	hsa-miR-411	CLIP-seq
MIRT2040305	hsa-miR-4258	CLIP-seq
MIRT1141818	hsa-miR-4294	CLIP-seq
MIRT1141819	hsa-miR-433	CLIP-seq
MIRT1141822	hsa-miR-4457	CLIP-seq
MIRT2040306	hsa-miR-4635	CLIP-seq
MIRT1141827	hsa-miR-4645-5p	CLIP-seq
MIRT1141830	hsa-miR-4673	CLIP-seq
MIRT1141831	hsa-miR-4689	CLIP-seq
MIRT2040307	hsa-miR-4707-3p	CLIP-seq
MIRT2040308	hsa-miR-4735-5p	CLIP-seq
MIRT2040309	hsa-miR-4775	CLIP-seq
MIRT1141836	hsa-miR-4784	CLIP-seq
MIRT1141837	hsa-miR-483-5p	CLIP-seq
MIRT1141838	hsa-miR-484	CLIP-seq
MIRT1141843	hsa-miR-5096	CLIP-seq
MIRT1141845	hsa-miR-513b	CLIP-seq
MIRT2040310	hsa-miR-590-3p	CLIP-seq
MIRT1141856	hsa-miR-641	CLIP-seq
MIRT1141859	hsa-miR-924	CLIP-seq
MIRT1141861	hsa-miR-942	CLIP-seq
MIRT1141769	hsa-let-7a	CLIP-seq
MIRT1141770	hsa-let-7b	CLIP-seq
MIRT1141771	hsa-let-7c	CLIP-seq
MIRT1141772	hsa-let-7d	CLIP-seq
MIRT1141773	hsa-let-7e	CLIP-seq
MIRT1141774	hsa-let-7f	CLIP-seq
MIRT1141775	hsa-let-7g	CLIP-seq
MIRT1141776	hsa-let-7i	CLIP-seq
MIRT1141777	hsa-miR-101	CLIP-seq
MIRT2270086	hsa-miR-1178	CLIP-seq
MIRT2270087	hsa-miR-1245	CLIP-seq
MIRT1141780	hsa-miR-1266	CLIP-seq
MIRT1141781	hsa-miR-1278	CLIP-seq
MIRT1141782	hsa-miR-1279	CLIP-seq
MIRT2270088	hsa-miR-142-5p	CLIP-seq
MIRT2270089	hsa-miR-150	CLIP-seq
MIRT1141784	hsa-miR-197	CLIP-seq
MIRT2270090	hsa-miR-1976	CLIP-seq
MIRT1141785	hsa-miR-198	CLIP-seq
MIRT1141786	hsa-miR-202	CLIP-seq
MIRT1141789	hsa-miR-2355-3p	CLIP-seq
MIRT1141795	hsa-miR-30a	CLIP-seq
MIRT1141796	hsa-miR-30b	CLIP-seq
MIRT1141797	hsa-miR-30c	CLIP-seq
MIRT1141798	hsa-miR-30d	CLIP-seq
MIRT1141799	hsa-miR-30e	CLIP-seq
MIRT1141800	hsa-miR-3125	CLIP-seq
MIRT1141801	hsa-miR-3127-5p	CLIP-seq
MIRT1141802	hsa-miR-3140-3p	CLIP-seq
MIRT2040301	hsa-miR-3149	CLIP-seq
MIRT1141803	hsa-miR-3150b-3p	CLIP-seq
MIRT1141804	hsa-miR-3155	CLIP-seq
MIRT1141805	hsa-miR-3155b	CLIP-seq
MIRT2270091	hsa-miR-3178	CLIP-seq
MIRT2270092	hsa-miR-3199	CLIP-seq
MIRT1141806	hsa-miR-330-3p	CLIP-seq
MIRT1141807	hsa-miR-335	CLIP-seq
MIRT2270093	hsa-miR-338-5p	CLIP-seq
MIRT1141808	hsa-miR-3607-5p	CLIP-seq
MIRT2270094	hsa-miR-3653	CLIP-seq
MIRT1141812	hsa-miR-3659	CLIP-seq
MIRT2040303	hsa-miR-3663-5p	CLIP-seq
MIRT1141815	hsa-miR-3916	CLIP-seq
MIRT1141816	hsa-miR-3918	CLIP-seq
MIRT2040304	hsa-miR-411	CLIP-seq
MIRT2040305	hsa-miR-4258	CLIP-seq
MIRT1141818	hsa-miR-4294	CLIP-seq
MIRT1141820	hsa-miR-4421	CLIP-seq
MIRT1141823	hsa-miR-4458	CLIP-seq
MIRT1141824	hsa-miR-4497	CLIP-seq
MIRT1141825	hsa-miR-4500	CLIP-seq
MIRT1141826	hsa-miR-4518	CLIP-seq
MIRT1141827	hsa-miR-4645-5p	CLIP-seq
MIRT1141828	hsa-miR-4646-3p	CLIP-seq
MIRT1141829	hsa-miR-4658	CLIP-seq
MIRT1141830	hsa-miR-4673	CLIP-seq
MIRT1141831	hsa-miR-4689	CLIP-seq
MIRT2040307	hsa-miR-4707-3p	CLIP-seq
MIRT1141832	hsa-miR-4712-5p	CLIP-seq
MIRT2040308	hsa-miR-4735-5p	CLIP-seq
MIRT1141834	hsa-miR-4740-3p	CLIP-seq
MIRT1141835	hsa-miR-4753-3p	CLIP-seq
MIRT2270095	hsa-miR-4757-5p	CLIP-seq
MIRT2040309	hsa-miR-4775	CLIP-seq
MIRT1141836	hsa-miR-4784	CLIP-seq
MIRT1141837	hsa-miR-483-5p	CLIP-seq
MIRT1141838	hsa-miR-484	CLIP-seq
MIRT1141843	hsa-miR-5096	CLIP-seq
MIRT1141852	hsa-miR-520g	CLIP-seq
MIRT1141853	hsa-miR-520h	CLIP-seq
MIRT2270096	hsa-miR-548a-5p	CLIP-seq
MIRT2270097	hsa-miR-548ab	CLIP-seq
MIRT2270098	hsa-miR-548ak	CLIP-seq
MIRT2270099	hsa-miR-548b-5p	CLIP-seq
MIRT2270100	hsa-miR-548c-5p	CLIP-seq
MIRT2270101	hsa-miR-548d-5p	CLIP-seq
MIRT2270102	hsa-miR-548h	CLIP-seq
MIRT2270103	hsa-miR-548i	CLIP-seq
MIRT2270104	hsa-miR-548j	CLIP-seq
MIRT2270105	hsa-miR-548k	CLIP-seq
MIRT2270106	hsa-miR-548l	CLIP-seq
MIRT2270107	hsa-miR-548w	CLIP-seq
MIRT2270108	hsa-miR-548y	CLIP-seq
MIRT2270109	hsa-miR-559	CLIP-seq
MIRT1141854	hsa-miR-574-5p	CLIP-seq
MIRT2270110	hsa-miR-587	CLIP-seq
MIRT2040310	hsa-miR-590-3p	CLIP-seq
MIRT2270111	hsa-miR-640	CLIP-seq
MIRT1141857	hsa-miR-770-5p	CLIP-seq
MIRT1141859	hsa-miR-924	CLIP-seq
MIRT1141861	hsa-miR-942	CLIP-seq
MIRT1141862	hsa-miR-98	CLIP-seq
MIRT1141769	hsa-let-7a	CLIP-seq
MIRT1141770	hsa-let-7b	CLIP-seq
MIRT1141771	hsa-let-7c	CLIP-seq
MIRT1141772	hsa-let-7d	CLIP-seq
MIRT1141773	hsa-let-7e	CLIP-seq
MIRT1141774	hsa-let-7f	CLIP-seq
MIRT1141775	hsa-let-7g	CLIP-seq
MIRT1141776	hsa-let-7i	CLIP-seq
MIRT1141777	hsa-miR-101	CLIP-seq
MIRT2270086	hsa-miR-1178	CLIP-seq
MIRT1141781	hsa-miR-1278	CLIP-seq
MIRT1141786	hsa-miR-202	CLIP-seq
MIRT1141795	hsa-miR-30a	CLIP-seq
MIRT1141796	hsa-miR-30b	CLIP-seq
MIRT1141797	hsa-miR-30c	CLIP-seq
MIRT1141798	hsa-miR-30d	CLIP-seq
MIRT1141799	hsa-miR-30e	CLIP-seq
MIRT1141803	hsa-miR-3150b-3p	CLIP-seq
MIRT1141808	hsa-miR-3607-5p	CLIP-seq
MIRT1141812	hsa-miR-3659	CLIP-seq
MIRT1141823	hsa-miR-4458	CLIP-seq
MIRT1141824	hsa-miR-4497	CLIP-seq
MIRT1141825	hsa-miR-4500	CLIP-seq
MIRT1141829	hsa-miR-4658	CLIP-seq
MIRT1141831	hsa-miR-4689	CLIP-seq
MIRT1141836	hsa-miR-4784	CLIP-seq
MIRT1141854	hsa-miR-574-5p	CLIP-seq
MIRT1141862	hsa-miR-98	CLIP-seq
MIRT2040301	hsa-miR-3149	CLIP-seq
MIRT2270091	hsa-miR-3178	CLIP-seq
MIRT2270092	hsa-miR-3199	CLIP-seq
MIRT2040304	hsa-miR-411	CLIP-seq
MIRT2040305	hsa-miR-4258	CLIP-seq
MIRT2040307	hsa-miR-4707-3p	CLIP-seq
MIRT2040308	hsa-miR-4735-5p	CLIP-seq
MIRT2040309	hsa-miR-4775	CLIP-seq
MIRT1141837	hsa-miR-483-5p	CLIP-seq
MIRT2040310	hsa-miR-590-3p	CLIP-seq
MIRT2040301	hsa-miR-3149	CLIP-seq
MIRT2040304	hsa-miR-411	CLIP-seq
MIRT2040305	hsa-miR-4258	CLIP-seq
MIRT2040307	hsa-miR-4707-3p	CLIP-seq
MIRT2040308	hsa-miR-4735-5p	CLIP-seq
MIRT2040309	hsa-miR-4775	CLIP-seq
MIRT1141837	hsa-miR-483-5p	CLIP-seq
MIRT2040310	hsa-miR-590-3p	CLIP-seq
MIRT2569143	hsa-miR-122	CLIP-seq
MIRT1141780	hsa-miR-1266	CLIP-seq
MIRT1141782	hsa-miR-1279	CLIP-seq
MIRT2569144	hsa-miR-130a	CLIP-seq
MIRT2569145	hsa-miR-130b	CLIP-seq
MIRT1141784	hsa-miR-197	CLIP-seq
MIRT2270090	hsa-miR-1976	CLIP-seq
MIRT2569146	hsa-miR-301a	CLIP-seq
MIRT2569147	hsa-miR-301b	CLIP-seq
MIRT1141801	hsa-miR-3127-5p	CLIP-seq
MIRT2569148	hsa-miR-3135b	CLIP-seq
MIRT2040301	hsa-miR-3149	CLIP-seq
MIRT2569149	hsa-miR-320e	CLIP-seq
MIRT2569150	hsa-miR-3666	CLIP-seq
MIRT1141816	hsa-miR-3918	CLIP-seq
MIRT2040304	hsa-miR-411	CLIP-seq
MIRT2040305	hsa-miR-4258	CLIP-seq
MIRT2569151	hsa-miR-4295	CLIP-seq
MIRT1141820	hsa-miR-4421	CLIP-seq
MIRT1141826	hsa-miR-4518	CLIP-seq
MIRT2569152	hsa-miR-4532	CLIP-seq
MIRT2569153	hsa-miR-454	CLIP-seq
MIRT2040307	hsa-miR-4707-3p	CLIP-seq
MIRT2040308	hsa-miR-4735-5p	CLIP-seq
MIRT2040309	hsa-miR-4775	CLIP-seq
MIRT1141837	hsa-miR-483-5p	CLIP-seq
MIRT2569154	hsa-miR-498	CLIP-seq
MIRT1141843	hsa-miR-5096	CLIP-seq
MIRT2040310	hsa-miR-590-3p	CLIP-seq
MIRT2569155	hsa-miR-720	CLIP-seq
MIRT2569143	hsa-miR-122	CLIP-seq
MIRT1141780	hsa-miR-1266	CLIP-seq
MIRT1141782	hsa-miR-1279	CLIP-seq
MIRT2569144	hsa-miR-130a	CLIP-seq
MIRT2569145	hsa-miR-130b	CLIP-seq
MIRT1141784	hsa-miR-197	CLIP-seq
MIRT2569146	hsa-miR-301a	CLIP-seq
MIRT2569147	hsa-miR-301b	CLIP-seq
MIRT1141801	hsa-miR-3127-5p	CLIP-seq
MIRT2569148	hsa-miR-3135b	CLIP-seq
MIRT2040301	hsa-miR-3149	CLIP-seq
MIRT2569149	hsa-miR-320e	CLIP-seq
MIRT2569150	hsa-miR-3666	CLIP-seq
MIRT1141816	hsa-miR-3918	CLIP-seq
MIRT2040304	hsa-miR-411	CLIP-seq
MIRT2040305	hsa-miR-4258	CLIP-seq
MIRT2569151	hsa-miR-4295	CLIP-seq
MIRT1141826	hsa-miR-4518	CLIP-seq
MIRT2569152	hsa-miR-4532	CLIP-seq
MIRT2569153	hsa-miR-454	CLIP-seq
MIRT2040307	hsa-miR-4707-3p	CLIP-seq
MIRT2040308	hsa-miR-4735-5p	CLIP-seq
MIRT2040309	hsa-miR-4775	CLIP-seq
MIRT1141837	hsa-miR-483-5p	CLIP-seq
MIRT2569154	hsa-miR-498	CLIP-seq
MIRT1141843	hsa-miR-5096	CLIP-seq
MIRT2040310	hsa-miR-590-3p	CLIP-seq
MIRT2569155	hsa-miR-720	CLIP-seq

Gene ontology (GO) Show/Hide all (31)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000151	Component	Ubiquitin ligase complex	IEA
GO:0001223	Function	Transcription coactivator binding	IPI	17641689
GO:0003677	Function	DNA binding	IEA
GO:0003712	Function	Transcription coregulator activity	IEA
GO:0003713	Function	Transcription coactivator activity	IBA
GO:0003713	Function	Transcription coactivator activity	IDA	12037571
GO:0005515	Function	Protein binding	IPI	14576168, 15175163, 22479149, 24882805, 24981860, 28514442, 33961781, 35271311
GO:0005634	Component	Nucleus	IDA	24882805
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	TAS	10024883
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	IEA
GO:0005654	Component	Nucleoplasm	TAS
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	TAS	10024883
GO:0016020	Component	Membrane	HDA	19946888
GO:0016567	Process	Protein ubiquitination	IEA
GO:0016592	Component	Mediator complex	IBA
GO:0016592	Component	Mediator complex	IDA	12037571, 14638676
GO:0016592	Component	Mediator complex	IEA
GO:0016592	Component	Mediator complex	IMP	17641689
GO:0016592	Component	Mediator complex	TAS	9234719
GO:0032968	Process	Positive regulation of transcription elongation by RNA polymerase II	NAS	11559591
GO:0035019	Process	Somatic stem cell population maintenance	IEA
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IDA	12037571
GO:0051123	Process	RNA polymerase II preinitiation complex assembly	NAS	11559591
GO:0060261	Process	Positive regulation of transcription initiation by RNA polymerase II	NAS	11559591
GO:0061630	Function	Ubiquitin protein ligase activity	IEA
GO:0070847	Component	Core mediator complex	IBA
GO:0070847	Component	Core mediator complex	IPI	24882805

Other IDs

• MIM: 602984
• HGNC: 19970
• e!Ensembl: ENSG00000133997

Protein

• UniProt ID: O75586
• Protein name: Mediator of RNA polymerase II transcription subunit 6 (Activator-recruited cofactor 33 kDa component) (ARC33) (Mediator complex subunit 6) (hMed6) (Renal carcinoma antigen NY-REN-28)
• Protein function: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RN
• PDB: 7EMF , 7ENA , 7ENC , 7ENJ , 7LBM , 7NVR , 8GXQ , 8GXS , 8T9D , 8TQW , 8TRH
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF04934	Med6	13 → 140	MED6 mediator sub complex component	Family

• Sequence:

  MAAVDIRDNLLGISWVDSSWIPILNSGSVLDYFSERSNPFYDRTCNNEVVKMQRLTLEHL
  NQMVGIEYILLHAQEPILFIIRKQQRQSPAQVIPLADYYIIAGVIYQAPDLGSVINSRVL
  TAVHGIQSAFDEAMSYCRYHPSKGYWWHFKDHEEQDKVRPKAKRKEEPSSIFQRQRVDAL
  LLDLRQKFPPKFVQLKPGEKPVPVDQTKKEAEPIPETVKPEEKETTKNVQQTVSAKGPPE
  KRMRLQ

• Sequence length: 246

Pathways

Reactome Pathway

PPARA activates gene expression

Generic Transcription Pathway

Transcriptional regulation of white adipocyte differentiation

Related Genes

Sort by: Blended Diseases Pathways Evidence source

MED8 2 shared pathwaysPPARA activates gene expression, Transcriptional regulation of white adipocyte differentiation Related via 2 shared pathways including PPARA activates gene expression, Transcriptional regulation of white adipocyte differentiation. MED19 2 shared pathwaysPPARA activates gene expression, Transcriptional regulation of white adipocyte differentiation Related via 2 shared pathways including PPARA activates gene expression, Transcriptional regulation of white adipocyte differentiation. CDK19 2 shared pathwaysPPARA activates gene expression, Transcriptional regulation of white adipocyte differentiation Related via 2 shared pathways including PPARA activates gene expression, Transcriptional regulation of white adipocyte differentiation. MED11 2 shared pathwaysPPARA activates gene expression, Transcriptional regulation of white adipocyte differentiation Related via 2 shared pathways including PPARA activates gene expression, Transcriptional regulation of white adipocyte differentiation. MED31 2 shared pathwaysPPARA activates gene expression, Transcriptional regulation of white adipocyte differentiation Related via 2 shared pathways including PPARA activates gene expression, Transcriptional regulation of white adipocyte differentiation.

Related Gene	Shared Diseases	Shared Disease Names	Shared Pathways	Shared Pathway Names	Shared Evidence Sources	Shared Evidence Names
MED8	0	[]	2	["PPARA activates gene expression","Transcriptional regulation of white adipocyte differentiation"]	0	[]
MED19	0	[]	2	["PPARA activates gene expression","Transcriptional regulation of white adipocyte differentiation"]	0	[]
CDK19	0	[]	2	["PPARA activates gene expression","Transcriptional regulation of white adipocyte differentiation"]	0	[]
MED11	0	[]	2	["PPARA activates gene expression","Transcriptional regulation of white adipocyte differentiation"]	0	[]
MED31	0	[]	2	["PPARA activates gene expression","Transcriptional regulation of white adipocyte differentiation"]	0	[]

Diseases Linked via Similar Genes

Neurodevelopmental disorder Linked via 2 of 5 related genesCDK19, MED11 Attention deficit hyperactivity disorder Linked via 1 of 5 related genesMED8 Autism Linked via 1 of 5 related genesMED8 Developmental and epileptic encephalopathy Linked via 1 of 5 related genesCDK19 Major depressive disorder Linked via 1 of 5 related genesCDK19

Disease	Linked Via (Gene Count)	Linked Via (Gene Names)
Neurodevelopmental disorder	2	["CDK19","MED11"]
Attention deficit hyperactivity disorder	1	["MED8"]
Autism	1	["MED8"]
Developmental and epileptic encephalopathy	1	["CDK19"]
Major depressive disorder	1	["CDK19"]