Gene Gene information from NCBI Gene database. Download as csv Download as pdf
Entrez ID	2790
Gene name	G protein subunit gamma 10
Gene symbol	GNG10
Synonyms (NCBI Gene)	-
Chromosome	9
Chromosome location	9q31.3

189 Show/Hide all (189)

miRTarBase ID	miRNA	Experiments	Reference
MIRT002606	hsa-miR-124-3p	Microarray	15685193
MIRT002606	hsa-miR-124-3p	Microarray	18668037
MIRT035960	hsa-miR-1301-3p	CLASH	23622248
MIRT1024254	hsa-miR-1229	CLIP-seq
MIRT1024255	hsa-miR-1297	CLIP-seq
MIRT1024256	hsa-miR-1972	CLIP-seq
MIRT1024257	hsa-miR-205	CLIP-seq
MIRT1024258	hsa-miR-26a	CLIP-seq
MIRT1024259	hsa-miR-26b	CLIP-seq
MIRT1024260	hsa-miR-3130-5p	CLIP-seq
MIRT1024261	hsa-miR-3143	CLIP-seq
MIRT1024262	hsa-miR-323-5p	CLIP-seq
MIRT1024263	hsa-miR-3646	CLIP-seq
MIRT1024264	hsa-miR-3662	CLIP-seq
MIRT1024265	hsa-miR-3672	CLIP-seq
MIRT1024266	hsa-miR-3680	CLIP-seq
MIRT1024267	hsa-miR-376a	CLIP-seq
MIRT1024268	hsa-miR-376b	CLIP-seq
MIRT1024269	hsa-miR-412	CLIP-seq
MIRT1024270	hsa-miR-4307	CLIP-seq
MIRT1024271	hsa-miR-4328	CLIP-seq
MIRT1024272	hsa-miR-4446-3p	CLIP-seq
MIRT1024273	hsa-miR-4465	CLIP-seq
MIRT1024274	hsa-miR-4482	CLIP-seq
MIRT1024275	hsa-miR-4635	CLIP-seq
MIRT1024276	hsa-miR-4639-5p	CLIP-seq
MIRT1024277	hsa-miR-4656	CLIP-seq
MIRT1024278	hsa-miR-4677-3p	CLIP-seq
MIRT1024279	hsa-miR-4679	CLIP-seq
MIRT1024280	hsa-miR-4686	CLIP-seq
MIRT1024281	hsa-miR-4691-5p	CLIP-seq
MIRT1024282	hsa-miR-4712-5p	CLIP-seq
MIRT1024283	hsa-miR-4717-5p	CLIP-seq
MIRT1024284	hsa-miR-4729	CLIP-seq
MIRT1024285	hsa-miR-4762-5p	CLIP-seq
MIRT1024286	hsa-miR-494	CLIP-seq
MIRT1024287	hsa-miR-526b	CLIP-seq
MIRT1024288	hsa-miR-543	CLIP-seq
MIRT1024289	hsa-miR-548c-3p	CLIP-seq
MIRT1024290	hsa-miR-548t	CLIP-seq
MIRT1024291	hsa-miR-567	CLIP-seq
MIRT1024292	hsa-miR-578	CLIP-seq
MIRT1024293	hsa-miR-583	CLIP-seq
MIRT1024294	hsa-miR-626	CLIP-seq
MIRT1024295	hsa-miR-767-3p	CLIP-seq
MIRT1024296	hsa-miR-770-5p	CLIP-seq
MIRT1024297	hsa-miR-802	CLIP-seq
MIRT1024298	hsa-miR-876-3p	CLIP-seq
MIRT1549311	hsa-miR-3675-5p	CLIP-seq
MIRT1024284	hsa-miR-4729	CLIP-seq
MIRT1549312	hsa-miR-4789-5p	CLIP-seq
MIRT1549313	hsa-miR-486-3p	CLIP-seq
MIRT1024261	hsa-miR-3143	CLIP-seq
MIRT1549311	hsa-miR-3675-5p	CLIP-seq
MIRT1024284	hsa-miR-4729	CLIP-seq
MIRT1549312	hsa-miR-4789-5p	CLIP-seq
MIRT1549313	hsa-miR-486-3p	CLIP-seq
MIRT1024288	hsa-miR-543	CLIP-seq
MIRT1556461	hsa-miR-579	CLIP-seq
MIRT2003751	hsa-miR-1273e	CLIP-seq
MIRT2003752	hsa-miR-2113	CLIP-seq
MIRT2003753	hsa-miR-218	CLIP-seq
MIRT2003754	hsa-miR-23a	CLIP-seq
MIRT2003755	hsa-miR-23b	CLIP-seq
MIRT2003756	hsa-miR-23c	CLIP-seq
MIRT2003757	hsa-miR-2682	CLIP-seq
MIRT2003758	hsa-miR-3617	CLIP-seq
MIRT1549311	hsa-miR-3675-5p	CLIP-seq
MIRT2003759	hsa-miR-3714	CLIP-seq
MIRT2003760	hsa-miR-3910	CLIP-seq
MIRT2003761	hsa-miR-3913-3p	CLIP-seq
MIRT2003762	hsa-miR-3977	CLIP-seq
MIRT1024270	hsa-miR-4307	CLIP-seq
MIRT2003763	hsa-miR-4422	CLIP-seq
MIRT2003764	hsa-miR-4493	CLIP-seq
MIRT2003765	hsa-miR-449c	CLIP-seq
MIRT1024275	hsa-miR-4635	CLIP-seq
MIRT1024280	hsa-miR-4686	CLIP-seq
MIRT2003766	hsa-miR-4709-5p	CLIP-seq
MIRT1024284	hsa-miR-4729	CLIP-seq
MIRT1024285	hsa-miR-4762-5p	CLIP-seq
MIRT1549312	hsa-miR-4789-5p	CLIP-seq
MIRT1549313	hsa-miR-486-3p	CLIP-seq
MIRT2003767	hsa-miR-545	CLIP-seq
MIRT1024289	hsa-miR-548c-3p	CLIP-seq
MIRT1024291	hsa-miR-567	CLIP-seq
MIRT1556461	hsa-miR-579	CLIP-seq
MIRT2003768	hsa-miR-636	CLIP-seq
MIRT2003769	hsa-miR-641	CLIP-seq
MIRT2003770	hsa-miR-665	CLIP-seq
MIRT1024297	hsa-miR-802	CLIP-seq
MIRT2003771	hsa-miR-873	CLIP-seq
MIRT2236507	hsa-miR-1283	CLIP-seq
MIRT1024256	hsa-miR-1972	CLIP-seq
MIRT2236508	hsa-miR-330-3p	CLIP-seq
MIRT2236509	hsa-miR-3663-5p	CLIP-seq
MIRT2236510	hsa-miR-3919	CLIP-seq
MIRT2003764	hsa-miR-4493	CLIP-seq
MIRT1024283	hsa-miR-4717-5p	CLIP-seq
MIRT1024284	hsa-miR-4729	CLIP-seq
MIRT2236511	hsa-miR-520d-5p	CLIP-seq
MIRT2236512	hsa-miR-524-5p	CLIP-seq
MIRT1556461	hsa-miR-579	CLIP-seq
MIRT2236513	hsa-miR-651	CLIP-seq
MIRT2003761	hsa-miR-3913-3p	CLIP-seq
MIRT1024254	hsa-miR-1229	CLIP-seq
MIRT1024255	hsa-miR-1297	CLIP-seq
MIRT1024257	hsa-miR-205	CLIP-seq
MIRT1024258	hsa-miR-26a	CLIP-seq
MIRT1024259	hsa-miR-26b	CLIP-seq
MIRT1024260	hsa-miR-3130-5p	CLIP-seq
MIRT2540234	hsa-miR-3133	CLIP-seq
MIRT2540235	hsa-miR-3145-3p	CLIP-seq
MIRT2540236	hsa-miR-3163	CLIP-seq
MIRT1024262	hsa-miR-323-5p	CLIP-seq
MIRT2540237	hsa-miR-3613-3p	CLIP-seq
MIRT1024266	hsa-miR-3680	CLIP-seq
MIRT2540238	hsa-miR-3688-3p	CLIP-seq
MIRT2540239	hsa-miR-3924	CLIP-seq
MIRT1024269	hsa-miR-412	CLIP-seq
MIRT2540240	hsa-miR-4282	CLIP-seq
MIRT1024270	hsa-miR-4307	CLIP-seq
MIRT1024271	hsa-miR-4328	CLIP-seq
MIRT1024273	hsa-miR-4465	CLIP-seq
MIRT1024274	hsa-miR-4482	CLIP-seq
MIRT2003766	hsa-miR-4709-5p	CLIP-seq
MIRT1024286	hsa-miR-494	CLIP-seq
MIRT2540241	hsa-miR-548k	CLIP-seq
MIRT2540242	hsa-miR-548n	CLIP-seq
MIRT1024290	hsa-miR-548t	CLIP-seq
MIRT2540243	hsa-miR-556-3p	CLIP-seq
MIRT1024291	hsa-miR-567	CLIP-seq
MIRT2540244	hsa-miR-568	CLIP-seq
MIRT1024293	hsa-miR-583	CLIP-seq
MIRT2003770	hsa-miR-665	CLIP-seq
MIRT1024297	hsa-miR-802	CLIP-seq
MIRT2003771	hsa-miR-873	CLIP-seq
MIRT1024298	hsa-miR-876-3p	CLIP-seq
MIRT1024254	hsa-miR-1229	CLIP-seq
MIRT2003751	hsa-miR-1273e	CLIP-seq
MIRT1024255	hsa-miR-1297	CLIP-seq
MIRT2681739	hsa-miR-1323	CLIP-seq
MIRT1024256	hsa-miR-1972	CLIP-seq
MIRT1024257	hsa-miR-205	CLIP-seq
MIRT2003752	hsa-miR-2113	CLIP-seq
MIRT2003753	hsa-miR-218	CLIP-seq
MIRT2003757	hsa-miR-2682	CLIP-seq
MIRT1024258	hsa-miR-26a	CLIP-seq
MIRT1024259	hsa-miR-26b	CLIP-seq
MIRT1024260	hsa-miR-3130-5p	CLIP-seq
MIRT2540234	hsa-miR-3133	CLIP-seq
MIRT2540235	hsa-miR-3145-3p	CLIP-seq
MIRT2540236	hsa-miR-3163	CLIP-seq
MIRT1024262	hsa-miR-323-5p	CLIP-seq
MIRT2540237	hsa-miR-3613-3p	CLIP-seq
MIRT1024265	hsa-miR-3672	CLIP-seq
MIRT1024266	hsa-miR-3680	CLIP-seq
MIRT2540238	hsa-miR-3688-3p	CLIP-seq
MIRT2003759	hsa-miR-3714	CLIP-seq
MIRT2003760	hsa-miR-3910	CLIP-seq
MIRT2540239	hsa-miR-3924	CLIP-seq
MIRT1024269	hsa-miR-412	CLIP-seq
MIRT2540240	hsa-miR-4282	CLIP-seq
MIRT1024270	hsa-miR-4307	CLIP-seq
MIRT1024271	hsa-miR-4328	CLIP-seq
MIRT1024273	hsa-miR-4465	CLIP-seq
MIRT1024274	hsa-miR-4482	CLIP-seq
MIRT2003764	hsa-miR-4493	CLIP-seq
MIRT2003765	hsa-miR-449c	CLIP-seq
MIRT1024275	hsa-miR-4635	CLIP-seq
MIRT1024278	hsa-miR-4677-3p	CLIP-seq
MIRT1024279	hsa-miR-4679	CLIP-seq
MIRT2003766	hsa-miR-4709-5p	CLIP-seq
MIRT1024283	hsa-miR-4717-5p	CLIP-seq
MIRT1024286	hsa-miR-494	CLIP-seq
MIRT1024289	hsa-miR-548c-3p	CLIP-seq
MIRT2540241	hsa-miR-548k	CLIP-seq
MIRT2540242	hsa-miR-548n	CLIP-seq
MIRT2681740	hsa-miR-548o	CLIP-seq
MIRT1024290	hsa-miR-548t	CLIP-seq
MIRT2540243	hsa-miR-556-3p	CLIP-seq
MIRT1024291	hsa-miR-567	CLIP-seq
MIRT2540244	hsa-miR-568	CLIP-seq
MIRT1024293	hsa-miR-583	CLIP-seq
MIRT2003768	hsa-miR-636	CLIP-seq
MIRT2003770	hsa-miR-665	CLIP-seq
MIRT1024297	hsa-miR-802	CLIP-seq
MIRT2003771	hsa-miR-873	CLIP-seq
MIRT1024298	hsa-miR-876-3p	CLIP-seq

13 Show/Hide all (13)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003924	Function	GTPase activity	TAS	7665596
GO:0005515	Function	Protein binding	IPI	25416956, 29892012, 31515488, 32296183
GO:0005834	Component	Heterotrimeric G-protein complex	IBA
GO:0005834	Component	Heterotrimeric G-protein complex	IEA
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS
GO:0007165	Process	Signal transduction	IEA
GO:0007165	Process	Signal transduction	TAS	7665596
GO:0007186	Process	G protein-coupled receptor signaling pathway	IBA
GO:0007186	Process	G protein-coupled receptor signaling pathway	IEA
GO:0016020	Component	Membrane	IEA
GO:0031681	Function	G-protein beta-subunit binding	IBA
GO:0031681	Function	G-protein beta-subunit binding	IEA

MIM	HGNC	e!Ensembl
604389	4402	ENSG00000242616

P50151

Protein name

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10

Protein function

Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G prote

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00631	G-gamma	5 → 68	GGL domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Abundantly and ubiquitously expressed.

Sequence

MSSGASASALQRLVEQLKLEAGVERIKVSQAAAELQQYCMQNACKDALLVGVPAGSNPFR
EPRSCALL

Sequence length

Interactions

View interactions

KEGG Pathway	Reactome Pathway
Ras signaling pathway	Activation of G protein gated Potassium channels
Chemokine signaling pathway	Glucagon signaling in metabolic regulation
Hormone signaling	G-protein activation
PI3K-Akt signaling pathway	Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
Apelin signaling pathway	ADP signalling through P2Y purinoceptor 12
Circadian entrainment	G beta:gamma signalling through PI3Kgamma
Retrograde endocannabinoid signaling	Prostacyclin signalling through prostacyclin receptor
Glutamatergic synapse	Adrenaline,noradrenaline inhibits insulin secretion
Cholinergic synapse	Ca2+ pathway
Serotonergic synapse	G alpha (q) signalling events
GABAergic synapse	G alpha (12/13) signalling events
Dopaminergic synapse	G beta:gamma signalling through PLC beta
Relaxin signaling pathway	G alpha (s) signalling events
Morphine addiction	ADP signalling through P2Y purinoceptor 1
Alcoholism	G alpha (i) signalling events
Human cytomegalovirus infection	G alpha (z) signalling events
Kaposi sarcoma-associated herpesvirus infection	Glucagon-type ligand receptors
Human immunodeficiency virus 1 infection	Thromboxane signalling through TP receptor
Pathways in cancer	Vasopressin regulates renal water homeostasis via Aquaporins
	Thrombin signalling through proteinase activated receptors (PARs)
	Presynaptic function of Kainate receptors
	Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
	G beta:gamma signalling through BTK
	G beta:gamma signalling through CDC42
	Extra-nuclear estrogen signaling
	ADORA2B mediated anti-inflammatory cytokines production
	Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits

Related Gene	Shared Disease Names	Shared Pathways	Shared Pathway Names	Shared Evidence Names
GNB2	[]	44	["Ras signaling pathway","Chemokine signaling pathway","Hormone signaling","Apelin signaling pathway","Circadian entrainment","Retrograde endocannabinoid signaling","Glutamatergic synapse","Cholinergic synapse","Serotonergic synapse","GABAergic synapse","Dopaminergic synapse","Relaxin signaling pathway"]	[]
GNG3	[]	44	["Ras signaling pathway","Chemokine signaling pathway","Hormone signaling","Apelin signaling pathway","Circadian entrainment","Retrograde endocannabinoid signaling","Glutamatergic synapse","Cholinergic synapse","Serotonergic synapse","GABAergic synapse","Dopaminergic synapse","Relaxin signaling pathway"]	[]
GNG4	[]	44	["Ras signaling pathway","Chemokine signaling pathway","Hormone signaling","Apelin signaling pathway","Circadian entrainment","Retrograde endocannabinoid signaling","Glutamatergic synapse","Cholinergic synapse","Serotonergic synapse","GABAergic synapse","Dopaminergic synapse","Relaxin signaling pathway"]	[]
GNG5	[]	44	["Ras signaling pathway","Chemokine signaling pathway","Hormone signaling","Apelin signaling pathway","Circadian entrainment","Retrograde endocannabinoid signaling","Glutamatergic synapse","Cholinergic synapse","Serotonergic synapse","GABAergic synapse","Dopaminergic synapse","Relaxin signaling pathway"]	[]
GNG7	[]	44	["Ras signaling pathway","Chemokine signaling pathway","Hormone signaling","Apelin signaling pathway","Circadian entrainment","Retrograde endocannabinoid signaling","Glutamatergic synapse","Cholinergic synapse","Serotonergic synapse","GABAergic synapse","Dopaminergic synapse","Relaxin signaling pathway"]	[]

GNG10 (G protein subunit gamma 10)

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