CA13 (carbonic anhydrase 13)

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Gene miRNA Gene ontology Other IDs Protein Pathways Related genes Diseases linked via similar genes

Gene

• Entrez ID: 377677
• Gene name: Carbonic anhydrase 13
• Gene symbol: CA13
• Synonyms (NCBI Gene): CAXIII
• Chromosome: 8
• Chromosome location: 8q21.2
• Summary: Carbonic anhydrases (CAs) are a family of zinc metalloenzymes. For background information on the CA family, see MIM 114800.[supplied by OMIM, Mar 2008]

miRNA Show/Hide all (274)

miRTarBase ID	miRNA	Experiments	Reference
MIRT016071	hsa-miR-374b-5p	Sequencing	20371350
MIRT021360	hsa-miR-9-5p	Microarray	17612493
MIRT026474	hsa-miR-192-5p	Microarray	19074876
MIRT031162	hsa-miR-19b-3p	Sequencing	20371350
MIRT031357	hsa-miR-18a-5p	Sequencing	20371350
MIRT856538	hsa-miR-1206	CLIP-seq
MIRT856539	hsa-miR-1262	CLIP-seq
MIRT856540	hsa-miR-1273f	CLIP-seq
MIRT856541	hsa-miR-1296	CLIP-seq
MIRT856542	hsa-miR-1827	CLIP-seq
MIRT856543	hsa-miR-24	CLIP-seq
MIRT856544	hsa-miR-2681	CLIP-seq
MIRT856545	hsa-miR-28-5p	CLIP-seq
MIRT856546	hsa-miR-2909	CLIP-seq
MIRT856547	hsa-miR-3139	CLIP-seq
MIRT856548	hsa-miR-3591-3p	CLIP-seq
MIRT856549	hsa-miR-3614-5p	CLIP-seq
MIRT856550	hsa-miR-3672	CLIP-seq
MIRT856551	hsa-miR-3689d	CLIP-seq
MIRT856552	hsa-miR-3926	CLIP-seq
MIRT856553	hsa-miR-3934	CLIP-seq
MIRT856554	hsa-miR-4284	CLIP-seq
MIRT856555	hsa-miR-4290	CLIP-seq
MIRT856556	hsa-miR-4311	CLIP-seq
MIRT856557	hsa-miR-4433	CLIP-seq
MIRT856558	hsa-miR-4436b-3p	CLIP-seq
MIRT856559	hsa-miR-4459	CLIP-seq
MIRT856560	hsa-miR-4477a	CLIP-seq
MIRT856561	hsa-miR-4514	CLIP-seq
MIRT856562	hsa-miR-4534	CLIP-seq
MIRT856563	hsa-miR-4645-5p	CLIP-seq
MIRT856564	hsa-miR-4673	CLIP-seq
MIRT856565	hsa-miR-4692	CLIP-seq
MIRT856566	hsa-miR-4701-3p	CLIP-seq
MIRT856567	hsa-miR-4722-5p	CLIP-seq
MIRT856568	hsa-miR-4733-3p	CLIP-seq
MIRT856569	hsa-miR-4742-5p	CLIP-seq
MIRT856570	hsa-miR-4761-3p	CLIP-seq
MIRT856571	hsa-miR-4768-3p	CLIP-seq
MIRT856572	hsa-miR-4786-5p	CLIP-seq
MIRT856573	hsa-miR-4797-5p	CLIP-seq
MIRT856574	hsa-miR-4802-5p	CLIP-seq
MIRT856575	hsa-miR-542-3p	CLIP-seq
MIRT856576	hsa-miR-548m	CLIP-seq
MIRT856577	hsa-miR-548s	CLIP-seq
MIRT856578	hsa-miR-579	CLIP-seq
MIRT856579	hsa-miR-656	CLIP-seq
MIRT856580	hsa-miR-661	CLIP-seq
MIRT856581	hsa-miR-708	CLIP-seq
MIRT856582	hsa-miR-766	CLIP-seq
MIRT856583	hsa-miR-769-5p	CLIP-seq
MIRT856584	hsa-miR-940	CLIP-seq
MIRT856539	hsa-miR-1262	CLIP-seq
MIRT856540	hsa-miR-1273f	CLIP-seq
MIRT856542	hsa-miR-1827	CLIP-seq
MIRT1954400	hsa-miR-338-3p	CLIP-seq
MIRT1954401	hsa-miR-3612	CLIP-seq
MIRT856549	hsa-miR-3614-5p	CLIP-seq
MIRT856550	hsa-miR-3672	CLIP-seq
MIRT856551	hsa-miR-3689d	CLIP-seq
MIRT856552	hsa-miR-3926	CLIP-seq
MIRT1954402	hsa-miR-3929	CLIP-seq
MIRT1954403	hsa-miR-4419b	CLIP-seq
MIRT856557	hsa-miR-4433	CLIP-seq
MIRT1954404	hsa-miR-4443	CLIP-seq
MIRT856559	hsa-miR-4459	CLIP-seq
MIRT1954405	hsa-miR-4478	CLIP-seq
MIRT856561	hsa-miR-4514	CLIP-seq
MIRT1954406	hsa-miR-4530	CLIP-seq
MIRT856562	hsa-miR-4534	CLIP-seq
MIRT1954407	hsa-miR-455-5p	CLIP-seq
MIRT1954408	hsa-miR-4691-3p	CLIP-seq
MIRT856565	hsa-miR-4692	CLIP-seq
MIRT856566	hsa-miR-4701-3p	CLIP-seq
MIRT856571	hsa-miR-4768-3p	CLIP-seq
MIRT856572	hsa-miR-4786-5p	CLIP-seq
MIRT856573	hsa-miR-4797-5p	CLIP-seq
MIRT856574	hsa-miR-4802-5p	CLIP-seq
MIRT1954409	hsa-miR-485-5p	CLIP-seq
MIRT1954410	hsa-miR-518a-5p	CLIP-seq
MIRT1954411	hsa-miR-527	CLIP-seq
MIRT856575	hsa-miR-542-3p	CLIP-seq
MIRT856577	hsa-miR-548s	CLIP-seq
MIRT1954412	hsa-miR-550a	CLIP-seq
MIRT856578	hsa-miR-579	CLIP-seq
MIRT1954413	hsa-miR-650	CLIP-seq
MIRT856580	hsa-miR-661	CLIP-seq
MIRT1954414	hsa-miR-759	CLIP-seq
MIRT856582	hsa-miR-766	CLIP-seq
MIRT856583	hsa-miR-769-5p	CLIP-seq
MIRT856584	hsa-miR-940	CLIP-seq
MIRT856539	hsa-miR-1262	CLIP-seq
MIRT856540	hsa-miR-1273f	CLIP-seq
MIRT2191892	hsa-miR-1285	CLIP-seq
MIRT856541	hsa-miR-1296	CLIP-seq
MIRT856542	hsa-miR-1827	CLIP-seq
MIRT856545	hsa-miR-28-5p	CLIP-seq
MIRT856546	hsa-miR-2909	CLIP-seq
MIRT856547	hsa-miR-3139	CLIP-seq
MIRT2191893	hsa-miR-3187-5p	CLIP-seq
MIRT2191894	hsa-miR-335	CLIP-seq
MIRT856548	hsa-miR-3591-3p	CLIP-seq
MIRT1954401	hsa-miR-3612	CLIP-seq
MIRT856549	hsa-miR-3614-5p	CLIP-seq
MIRT2191895	hsa-miR-3664-5p	CLIP-seq
MIRT856550	hsa-miR-3672	CLIP-seq
MIRT2191896	hsa-miR-3689a-3p	CLIP-seq
MIRT2191897	hsa-miR-3689c	CLIP-seq
MIRT856551	hsa-miR-3689d	CLIP-seq
MIRT1954402	hsa-miR-3929	CLIP-seq
MIRT856555	hsa-miR-4290	CLIP-seq
MIRT1954403	hsa-miR-4419b	CLIP-seq
MIRT856557	hsa-miR-4433	CLIP-seq
MIRT856558	hsa-miR-4436b-3p	CLIP-seq
MIRT1954404	hsa-miR-4443	CLIP-seq
MIRT2191898	hsa-miR-4455	CLIP-seq
MIRT856559	hsa-miR-4459	CLIP-seq
MIRT1954405	hsa-miR-4478	CLIP-seq
MIRT856561	hsa-miR-4514	CLIP-seq
MIRT856562	hsa-miR-4534	CLIP-seq
MIRT1954407	hsa-miR-455-5p	CLIP-seq
MIRT856563	hsa-miR-4645-5p	CLIP-seq
MIRT2191899	hsa-miR-4649-3p	CLIP-seq
MIRT2191900	hsa-miR-4662a-5p	CLIP-seq
MIRT856564	hsa-miR-4673	CLIP-seq
MIRT1954408	hsa-miR-4691-3p	CLIP-seq
MIRT856565	hsa-miR-4692	CLIP-seq
MIRT856566	hsa-miR-4701-3p	CLIP-seq
MIRT2191901	hsa-miR-4714-5p	CLIP-seq
MIRT856567	hsa-miR-4722-5p	CLIP-seq
MIRT2191902	hsa-miR-4728-5p	CLIP-seq
MIRT2191903	hsa-miR-4760-3p	CLIP-seq
MIRT856570	hsa-miR-4761-3p	CLIP-seq
MIRT856571	hsa-miR-4768-3p	CLIP-seq
MIRT856572	hsa-miR-4786-5p	CLIP-seq
MIRT856573	hsa-miR-4797-5p	CLIP-seq
MIRT856574	hsa-miR-4802-5p	CLIP-seq
MIRT1954409	hsa-miR-485-5p	CLIP-seq
MIRT856575	hsa-miR-542-3p	CLIP-seq
MIRT2191904	hsa-miR-548c-3p	CLIP-seq
MIRT1954412	hsa-miR-550a	CLIP-seq
MIRT2191905	hsa-miR-550b	CLIP-seq
MIRT2191906	hsa-miR-571	CLIP-seq
MIRT856578	hsa-miR-579	CLIP-seq
MIRT2191907	hsa-miR-612	CLIP-seq
MIRT2191908	hsa-miR-627	CLIP-seq
MIRT1954413	hsa-miR-650	CLIP-seq
MIRT856580	hsa-miR-661	CLIP-seq
MIRT2191909	hsa-miR-664	CLIP-seq
MIRT2191910	hsa-miR-665	CLIP-seq
MIRT856581	hsa-miR-708	CLIP-seq
MIRT1954414	hsa-miR-759	CLIP-seq
MIRT856582	hsa-miR-766	CLIP-seq
MIRT856583	hsa-miR-769-5p	CLIP-seq
MIRT856584	hsa-miR-940	CLIP-seq
MIRT856540	hsa-miR-1273f	CLIP-seq
MIRT856542	hsa-miR-1827	CLIP-seq
MIRT856549	hsa-miR-3614-5p	CLIP-seq
MIRT856550	hsa-miR-3672	CLIP-seq
MIRT856551	hsa-miR-3689d	CLIP-seq
MIRT856552	hsa-miR-3926	CLIP-seq
MIRT856557	hsa-miR-4433	CLIP-seq
MIRT856559	hsa-miR-4459	CLIP-seq
MIRT856561	hsa-miR-4514	CLIP-seq
MIRT856562	hsa-miR-4534	CLIP-seq
MIRT856565	hsa-miR-4692	CLIP-seq
MIRT856571	hsa-miR-4768-3p	CLIP-seq
MIRT856572	hsa-miR-4786-5p	CLIP-seq
MIRT856574	hsa-miR-4802-5p	CLIP-seq
MIRT856577	hsa-miR-548s	CLIP-seq
MIRT856578	hsa-miR-579	CLIP-seq
MIRT856583	hsa-miR-769-5p	CLIP-seq
MIRT856584	hsa-miR-940	CLIP-seq
MIRT2445992	hsa-miR-1273d	CLIP-seq
MIRT2445993	hsa-miR-3622b-5p	CLIP-seq
MIRT2445994	hsa-miR-3675-3p	CLIP-seq
MIRT2191898	hsa-miR-4455	CLIP-seq
MIRT2445995	hsa-miR-4684-5p	CLIP-seq
MIRT2191904	hsa-miR-548c-3p	CLIP-seq
MIRT856538	hsa-miR-1206	CLIP-seq
MIRT2445992	hsa-miR-1273d	CLIP-seq
MIRT856540	hsa-miR-1273f	CLIP-seq
MIRT2191892	hsa-miR-1285	CLIP-seq
MIRT2495451	hsa-miR-1324	CLIP-seq
MIRT2495452	hsa-miR-181a	CLIP-seq
MIRT2495453	hsa-miR-181b	CLIP-seq
MIRT2495454	hsa-miR-181c	CLIP-seq
MIRT2495455	hsa-miR-181d	CLIP-seq
MIRT856542	hsa-miR-1827	CLIP-seq
MIRT2495456	hsa-miR-2115	CLIP-seq
MIRT2495457	hsa-miR-302f	CLIP-seq
MIRT2495458	hsa-miR-3074-5p	CLIP-seq
MIRT2191893	hsa-miR-3187-5p	CLIP-seq
MIRT1954400	hsa-miR-338-3p	CLIP-seq
MIRT2495459	hsa-miR-339-5p	CLIP-seq
MIRT2495460	hsa-miR-342-3p	CLIP-seq
MIRT856548	hsa-miR-3591-3p	CLIP-seq
MIRT2445993	hsa-miR-3622b-5p	CLIP-seq
MIRT2495461	hsa-miR-3667-5p	CLIP-seq
MIRT2445994	hsa-miR-3675-3p	CLIP-seq
MIRT2495462	hsa-miR-370	CLIP-seq
MIRT856552	hsa-miR-3926	CLIP-seq
MIRT2495463	hsa-miR-3977	CLIP-seq
MIRT2495464	hsa-miR-4262	CLIP-seq
MIRT2191898	hsa-miR-4455	CLIP-seq
MIRT2495465	hsa-miR-4496	CLIP-seq
MIRT2495466	hsa-miR-451b	CLIP-seq
MIRT1954406	hsa-miR-4530	CLIP-seq
MIRT856562	hsa-miR-4534	CLIP-seq
MIRT1954407	hsa-miR-455-5p	CLIP-seq
MIRT2495467	hsa-miR-4645-3p	CLIP-seq
MIRT856563	hsa-miR-4645-5p	CLIP-seq
MIRT856564	hsa-miR-4673	CLIP-seq
MIRT2445995	hsa-miR-4684-5p	CLIP-seq
MIRT2495468	hsa-miR-4696	CLIP-seq
MIRT856567	hsa-miR-4722-5p	CLIP-seq
MIRT856568	hsa-miR-4733-3p	CLIP-seq
MIRT856569	hsa-miR-4742-5p	CLIP-seq
MIRT2495469	hsa-miR-4749-3p	CLIP-seq
MIRT2495470	hsa-miR-4762-5p	CLIP-seq
MIRT856571	hsa-miR-4768-3p	CLIP-seq
MIRT856572	hsa-miR-4786-5p	CLIP-seq
MIRT2495471	hsa-miR-510	CLIP-seq
MIRT2495472	hsa-miR-516a-3p	CLIP-seq
MIRT1954410	hsa-miR-518a-5p	CLIP-seq
MIRT1954411	hsa-miR-527	CLIP-seq
MIRT2191904	hsa-miR-548c-3p	CLIP-seq
MIRT856577	hsa-miR-548s	CLIP-seq
MIRT1954412	hsa-miR-550a	CLIP-seq
MIRT856578	hsa-miR-579	CLIP-seq
MIRT2191907	hsa-miR-612	CLIP-seq
MIRT856580	hsa-miR-661	CLIP-seq
MIRT2495473	hsa-miR-676	CLIP-seq
MIRT856583	hsa-miR-769-5p	CLIP-seq
MIRT856584	hsa-miR-940	CLIP-seq
MIRT2445992	hsa-miR-1273d	CLIP-seq
MIRT2191892	hsa-miR-1285	CLIP-seq
MIRT856542	hsa-miR-1827	CLIP-seq
MIRT2191893	hsa-miR-3187-5p	CLIP-seq
MIRT856549	hsa-miR-3614-5p	CLIP-seq
MIRT2445993	hsa-miR-3622b-5p	CLIP-seq
MIRT2495461	hsa-miR-3667-5p	CLIP-seq
MIRT856550	hsa-miR-3672	CLIP-seq
MIRT2445994	hsa-miR-3675-3p	CLIP-seq
MIRT2191896	hsa-miR-3689a-3p	CLIP-seq
MIRT2191897	hsa-miR-3689c	CLIP-seq
MIRT856552	hsa-miR-3926	CLIP-seq
MIRT856557	hsa-miR-4433	CLIP-seq
MIRT2191898	hsa-miR-4455	CLIP-seq
MIRT856559	hsa-miR-4459	CLIP-seq
MIRT2495465	hsa-miR-4496	CLIP-seq
MIRT856561	hsa-miR-4514	CLIP-seq
MIRT2495466	hsa-miR-451b	CLIP-seq
MIRT1954407	hsa-miR-455-5p	CLIP-seq
MIRT2445995	hsa-miR-4684-5p	CLIP-seq
MIRT856565	hsa-miR-4692	CLIP-seq
MIRT2495468	hsa-miR-4696	CLIP-seq
MIRT856567	hsa-miR-4722-5p	CLIP-seq
MIRT2191902	hsa-miR-4728-5p	CLIP-seq
MIRT2495470	hsa-miR-4762-5p	CLIP-seq
MIRT856571	hsa-miR-4768-3p	CLIP-seq
MIRT856572	hsa-miR-4786-5p	CLIP-seq
MIRT2495471	hsa-miR-510	CLIP-seq
MIRT2191904	hsa-miR-548c-3p	CLIP-seq
MIRT856577	hsa-miR-548s	CLIP-seq
MIRT1954412	hsa-miR-550a	CLIP-seq
MIRT2191906	hsa-miR-571	CLIP-seq
MIRT856578	hsa-miR-579	CLIP-seq
MIRT2191907	hsa-miR-612	CLIP-seq
MIRT2191908	hsa-miR-627	CLIP-seq
MIRT856580	hsa-miR-661	CLIP-seq
MIRT2191910	hsa-miR-665	CLIP-seq
MIRT856583	hsa-miR-769-5p	CLIP-seq
MIRT856584	hsa-miR-940	CLIP-seq

Gene ontology (GO) Show/Hide all (12)

GO ID	Ontology	Definition	Evidence	Reference
GO:0004089	Function	Carbonate dehydratase activity	IBA
GO:0004089	Function	Carbonate dehydratase activity	IEA
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005737	Component	Cytoplasm	IBA
GO:0005829	Component	Cytosol	IBA
GO:0005829	Component	Cytosol	IEA
GO:0005829	Component	Cytosol	TAS
GO:0008270	Function	Zinc ion binding	IEA
GO:0016829	Function	Lyase activity	IEA
GO:0043209	Component	Myelin sheath	IEA
GO:0043231	Component	Intracellular membrane-bounded organelle	IEA
GO:0046872	Function	Metal ion binding	IEA

Other IDs

• MIM: 611436
• HGNC: 14914
• e!Ensembl: ENSG00000185015

Protein

• UniProt ID: Q8N1Q1
• Protein name: Carbonic anhydrase 13 (EC 4.2.1.1) (Carbonate dehydratase XIII) (Carbonic anhydrase XIII) (CA-XIII)
• Protein function: Reversible hydration of carbon dioxide.
• PDB: 3CZV , 3D0N , 3DA2 , 4HU1 , 4KNM , 4KNN , 4QIZ , 4QJP , 4QJX , 4QSJ , 5E2N , 5LLA , 5LLN , 5OGJ , 5OHH , 6G5U
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00194	Carb_anhydrase	5 → 260	Eukaryotic-type carbonic anhydrase	Domain

• Tissue specificity: TISSUE SPECIFICITY: Expressed in thymus, small intestine, spleen, prostate, ovary, colon and testis. {ECO:0000269|PubMed:14600151}.
• Sequence:

  MSRLSWGYREHNGPIHWKEFFPIADGDQQSPIEIKTKEVKYDSSLRPLSIKYDPSSAKII
  SNSGHSFNVDFDDTENKSVLRGGPLTGSYRLRQVHLHWGSADDHGSEHIVDGVSYAAELH
  VVHWNSDKYPSFVEAAHEPDGLAVLGVFLQIGEPNSQLQKITDTLDSIKEKGKQTRFTNF
  DLLSLLPPSWDYWTYPGSLTVPPLLESVTWIVLKQPINISSQQLAKFRSLLCTAEGEAAA
  FLVSNHRPPQPLKGRKVRASFH

• Sequence length: 262

Pathways

KEGG Pathway	Reactome Pathway
Nitrogen metabolism	Reversible hydration of carbon dioxide
Metabolic pathways

Related Genes

Sort by: Blended Diseases Pathways Evidence source

CA5B 2 shared pathwaysNitrogen metabolism, Reversible hydration of carbon dioxide Related via 2 shared pathways including Nitrogen metabolism, Reversible hydration of carbon dioxide. CA14 2 shared pathwaysNitrogen metabolism, Reversible hydration of carbon dioxide Related via 2 shared pathways including Nitrogen metabolism, Reversible hydration of carbon dioxide. CA3 2 shared pathwaysNitrogen metabolism, Reversible hydration of carbon dioxide Related via 2 shared pathways including Nitrogen metabolism, Reversible hydration of carbon dioxide. CA5A 2 shared pathwaysNitrogen metabolism, Reversible hydration of carbon dioxide Related via 2 shared pathways including Nitrogen metabolism, Reversible hydration of carbon dioxide. CA6 2 shared pathwaysNitrogen metabolism, Reversible hydration of carbon dioxide Related via 2 shared pathways including Nitrogen metabolism, Reversible hydration of carbon dioxide.

Related Gene	Shared Diseases	Shared Disease Names	Shared Pathways	Shared Pathway Names	Shared Evidence Sources	Shared Evidence Names
CA5B	0	[]	2	["Nitrogen metabolism","Reversible hydration of carbon dioxide"]	0	[]
CA14	0	[]	2	["Nitrogen metabolism","Reversible hydration of carbon dioxide"]	0	[]
CA3	0	[]	2	["Nitrogen metabolism","Reversible hydration of carbon dioxide"]	0	[]
CA5A	0	[]	2	["Nitrogen metabolism","Reversible hydration of carbon dioxide"]	0	[]
CA6	0	[]	2	["Nitrogen metabolism","Reversible hydration of carbon dioxide"]	0	[]

Diseases Linked via Similar Genes

Fatty liver Linked via 1 of 5 related genesCA3 Fatty liver, alcoholic Linked via 1 of 5 related genesCA3 Obesity Linked via 1 of 5 related genesCA3 Alzheimer disease Linked via 1 of 5 related genesCA5A Carbonic anhydrase deficiency Linked via 1 of 5 related genesCA5A

Disease	Linked Via (Gene Count)	Linked Via (Gene Names)
Fatty liver	1	["CA3"]
Fatty liver, alcoholic	1	["CA3"]
Obesity	1	["CA3"]
Alzheimer disease	1	["CA5A"]
Carbonic anhydrase deficiency	1	["CA5A"]