Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
KIDNEY DISEASES	C0022658 MESH:D007674	FGA	Unknown	8097946 8639778	CTD, Disgenet	Complement and coagulation cascades Platelet activation Neutrophil extracellular trap formation +17 more
		FGF2	Unknown	8995747	CTD, Disgenet	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +56 more
		GLIS2	Unknown	17618285	CTD, Disgenet	—
		GSTP1	Unknown	12868187	CTD, Disgenet	Glutathione metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450 +11 more
		HAVCR1	Unknown	19349640 20181666 20438795 21888673 23019274 24863737 24880025	CTD, Disgenet	Virion - Flavivirus and Alphavirus Efferocytosis
		HNF1B	Unknown	—	Disgenet	Maturity onset diabetes of the young
		HOXA11	Unknown	7596412	CTD, Disgenet	Transcriptional misregulation in cancer
		HOXD11	Unknown	7596412	CTD, Disgenet	—
		IFT122	Unknown	20493458	CTD, Disgenet	Hedgehog 'off' state Intraflagellar transport
		IFT140	Unknown	—	Disgenet	Hedgehog 'off' state Intraflagellar transport
		IGF1	Unknown	8825380	CTD, Disgenet	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +35 more
		IL17A	Unknown	37815028	CTD, Disgenet	Cytokine-cytokine receptor interaction IL-17 signaling pathway Th17 cell differentiation +5 more
		IL1RN	Unknown	9370186	CTD, Disgenet	Cytokine-cytokine receptor interaction Interleukin-10 signaling Interleukin-1 signaling
		IL33	Unknown	21949094	CTD, Disgenet	Cytokine-cytokine receptor interaction Necroptosis Cytosolic DNA-sensing pathway +5 more
		INF2	Unknown	—	Disgenet	Cytoskeleton in muscle cells
		INS	Unknown	—	Disgenet	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +39 more
		KL	Unknown	23665422	CTD, Disgenet	Pentose and glucuronate interconversions Ascorbate and aldarate metabolism Metabolic pathways +15 more
		LAMB2	Unknown	—	Disgenet	PI3K-Akt signaling pathway Focal adhesion ECM-receptor interaction +9 more
		LCN2	Unknown	19349640 20181666 20438795 27026710	CTD, Disgenet	IL-17 signaling pathway Interleukin-4 and Interleukin-13 signaling Neutrophil degranulation +2 more
		LEPR	Unknown	20567778 33345901	CTD, Disgenet	Cytokine-cytokine receptor interaction Neuroactive ligand-receptor interaction Hormone signaling +4 more
		LIPC	Unknown	—	Disgenet	Glycerolipid metabolism Metabolic pathways Cholesterol metabolism +2 more
		LMX1B	Unknown	—	Disgenet	—
		MIOX	Unknown	35100813	CTD	Ascorbate and aldarate metabolism Inositol phosphate metabolism Metabolic pathways +2 more
		MPO	Unknown	19913069	CTD, Disgenet	Drug metabolism - other enzymes Phagosome Neutrophil extracellular trap formation +4 more
		MT4	Unknown	19921116	CTD, Disgenet	—
		MTHFR	Unknown	18551038	CTD, Disgenet	One carbon pool by folate Metabolic pathways Antifolate resistance +2 more
		MXI1	Unknown	23316056	CTD, Disgenet	—
		NEK8	Unknown	18199800	CTD, Disgenet	—
		NFE2L2	Unknown	20605904	CTD, Disgenet	Protein processing in endoplasmic reticulum Parkinson disease Pathways in cancer +4 more
		NOS2	Unknown	18441258	CTD, Disgenet	Arginine biosynthesis Arginine and proline metabolism Metabolic pathways +21 more
		NPHP1	Unknown	—	Disgenet	Anchoring of the basal body to the plasma membrane
		NPHP3	Unknown	—	Disgenet	Trafficking of myristoylated proteins to the cilium
		NPHS1	Unknown	12012391 16382022	CTD, Disgenet	Nephrin family interactions
		NPR1	Unknown	20881240	CTD, Disgenet	Purine metabolism Metabolic pathways cGMP-PKG signaling pathway +9 more
		NQO1	Unknown	21613233	CTD, Disgenet	Ubiquinone and other terpenoid-quinone biosynthesis Metabolic pathways Biosynthesis of cofactors +5 more
		NR4A1	Unknown	24722447	CTD, Disgenet	MAPK signaling pathway PI3K-Akt signaling pathway Aldosterone synthesis and secretion +5 more
		PCSK5	Unknown	18519639	CTD, Disgenet	NGF processing Assembly of active LPL and LIPC lipase complexes
		PDSS2	Unknown	—	Disgenet	Terpenoid backbone biosynthesis Ubiquinol biosynthesis
		PLA2R1	Unknown	—	Disgenet	Phagosome Tuberculosis Acyl chain remodelling of PC +5 more
		PLCE1	Unknown	—	Disgenet	Inositol phosphate metabolism Metabolic pathways Ras signaling pathway +9 more
		POMC	Unknown	6143199	CTD, Disgenet	cAMP signaling pathway Neuroactive ligand-receptor interaction Hormone signaling +18 more
		PPARA	Unknown	16316343	CTD, Disgenet	PPAR signaling pathway cAMP signaling pathway Adipocytokine signaling pathway +16 more
		PTGS2	Unknown	19643929	CTD, Disgenet	Arachidonic acid metabolism Metabolic pathways NF-kappa B signaling pathway +29 more
		PYCARD	Unknown	22647887 24508291	CTD, Disgenet	Necroptosis NOD-like receptor signaling pathway Cytosolic DNA-sensing pathway +13 more
		RASAL1	Unknown	23665422	CTD, Disgenet	Ras signaling pathway Regulation of RAS by GAPs
		RBP4	Unknown	22061828	CTD, Disgenet	Retinoid cycle disease events The canonical retinoid cycle in rods (twilight vision) Retinoid metabolism disease events +1 more
		REN	Unknown	12414515 6156352 8723173	CTD, Disgenet	Renin-angiotensin system Renin secretion Diabetic cardiomyopathy +1 more
		RGN	Unknown	18805471	CTD, Disgenet	Pentose phosphate pathway Ascorbate and aldarate metabolism Metabolic pathways +2 more
		RPGRIP1L	Unknown	17558407 17558409	CTD, Disgenet	Hedgehog 'off' state Anchoring of the basal body to the plasma membrane
		RRM2B	Unknown	19138848	CTD, Disgenet	Purine metabolism Pyrimidine metabolism Glutathione metabolism +6 more
KIDNEY DISEASES, CYSTIC	MESH:D052177	INS	Unknown	9879822	CTD	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +39 more

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