Kidney disease

Parathyroid hormone synthesis, secretion and action Cation-coupled Chloride cotransporters Defective SLC12A3 causes Gitelman syndrome (GS)

Metal ion SLC transporters

Sphingolipid metabolism Metabolic pathways Sphingolipid signaling pathway Lysosome Necroptosis Glycosphingolipid metabolism +3 more

FoxO signaling pathway Peroxisome Longevity regulating pathway Longevity regulating pathway - multiple species Huntington disease Chemical carcinogenesis - reactive oxygen species Lipid and atherosclerosis Transcriptional activation of mitochondrial biogenesis Detoxification of Reactive Oxygen Species Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes +9 more

Platelet degranulation Nuclear signaling by ERBB4 ECM proteoglycans Scavenging by Class H Receptors +1 more

PI3K-Akt signaling pathway Apelin signaling pathway Focal adhesion ECM-receptor interaction Toll-like receptor signaling pathway GnRH secretion Human papillomavirus infection Degradation of the extracellular matrix Signaling by PDGF Integrin cell surface interactions Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) RUNX3 Regulates Immune Response and Cell Migration Post-translational protein phosphorylation +10 more

ECM-receptor interaction Toxicity of botulinum toxin type D (BoNT/D) Toxicity of botulinum toxin type A (BoNT/A) Toxicity of botulinum toxin type F (BoNT/F) Toxicity of botulinum toxin type E (BoNT/E) +2 more

Human papillomavirus infection Human T-cell leukemia virus 1 infection Pathways in cancer Hepatocellular carcinoma Gastric cancer Telomere Extension By Telomerase Formation of the beta-catenin:TCF transactivating complex +4 more

Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors Negative regulation of activity of TFAP2 (AP-2) family transcription factors TFAP2 (AP-2) family regulates transcription of other transcription factors Activation of the TFAP2 (AP-2) family of transcription factors TFAP2 (AP-2) family regulates transcription of growth factors and their receptors TFAP2 (AP-2) family regulates transcription of cell cycle factors TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation +4 more

Estrogen-dependent gene expression

MAPK signaling pathway Cytokine-cytokine receptor interaction FoxO signaling pathway Cell cycle Efferocytosis Cellular senescence TGF-beta signaling pathway Osteoclast differentiation Hippo signaling pathway Th17 cell differentiation Intestinal immune network for IgA production Relaxin signaling pathway Non-alcoholic fatty liver disease AGE-RAGE signaling pathway in diabetic complications Leishmaniasis Chagas disease Malaria Toxoplasmosis Amoebiasis Tuberculosis Hepatitis B Human T-cell leukemia virus 1 infection Pathways in cancer Proteoglycans in cancer Colorectal cancer Renal cell carcinoma Pancreatic cancer Chronic myeloid leukemia Hepatocellular carcinoma Gastric cancer Inflammatory bowel disease Rheumatoid arthritis Hypertrophic cardiomyopathy Dilated cardiomyopathy Diabetic cardiomyopathy Platelet degranulation Influenza Virus Induced Apoptosis Cell surface interactions at the vascular wall Molecules associated with elastic fibres Downregulation of TGF-beta receptor signaling TGF-beta receptor signaling activates SMADs TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) Syndecan interactions SMAD2/3 Phosphorylation Motif Mutants in Cancer TGFBR2 MSI Frameshift Mutants in Cancer TGFBR2 Kinase Domain Mutants in Cancer TGFBR1 KD Mutants in Cancer TGFBR1 LBD Mutants in Cancer Interleukin-4 and Interleukin-13 signaling RUNX3 regulates CDKN1A transcription Regulation of RUNX3 expression and activity RUNX3 regulates p14-ARF +49 more

Complement and coagulation cascades AGE-RAGE signaling pathway in diabetic complications Fluid shear stress and atherosclerosis Common Pathway of Fibrin Clot Formation Cell surface interactions at the vascular wall +2 more

tRNA modification in the nucleus and cytosol

Anchoring of the basal body to the plasma membrane

cGMP-PKG signaling pathway Axon guidance Effects of PIP2 hydrolysis Elevation of cytosolic Ca2+ levels TRP channels +2 more

Hedgehog 'off' state Intraflagellar transport

Cytoskeleton in muscle cells Epstein-Barr virus infection MicroRNAs in cancer Caspase-mediated cleavage of cytoskeletal proteins Striated Muscle Contraction Interleukin-4 and Interleukin-13 signaling Aggrephagy +4 more

Parathyroid hormone synthesis, secretion and action Stimuli-sensing channels

mTOR signaling pathway Wnt signaling pathway Axon guidance Hippo signaling pathway Signaling pathways regulating pluripotency of stem cells Melanogenesis Thyroid hormone signaling pathway Cushing syndrome Alzheimer disease Pathways of neurodegeneration - multiple diseases Human papillomavirus infection Pathways in cancer Proteoglycans in cancer Basal cell carcinoma Breast cancer Hepatocellular carcinoma Gastric cancer WNT ligand biogenesis and trafficking PCP/CE pathway +16 more

Hippo signaling pathway - multiple species

Intraflagellar transport

Anchoring of the basal body to the plasma membrane

Metal ion SLC transporters