Kidney disease

Steroid hormone biosynthesis Tryptophan metabolism Retinol metabolism Metabolism of xenobiotics by cytochrome P450 Metabolic pathways Ovarian steroidogenesis Chemical carcinogenesis - DNA adducts Chemical carcinogenesis - receptor activation Chemical carcinogenesis - reactive oxygen species Lipid and atherosclerosis PPARA activates gene expression Xenobiotics Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) Biosynthesis of protectins +12 more

Steroid hormone biosynthesis Caffeine metabolism Tryptophan metabolism Linoleic acid metabolism Retinol metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450 Metabolic pathways Chemical carcinogenesis - DNA adducts Chemical carcinogenesis - receptor activation Chemical carcinogenesis - reactive oxygen species Methylation Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) Aflatoxin activation and detoxification Biosynthesis of protectins Biosynthesis of maresin-like SPMs +15 more

Wnt signaling pathway Cytoskeleton in muscle cells

Endocytosis Gap junction degradation Formation of annular gap junctions Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis +2 more

Neddylation

Glycerolipid metabolism Glycerophospholipid metabolism Metabolic pathways Phosphatidylinositol signaling system Phospholipase D signaling pathway Choline metabolism in cancer Effects of PIP2 hydrolysis +4 more

Regulation of actin cytoskeleton Cytoskeleton in muscle cells RHO GTPases Activate Formins

Synthesis of Leukotrienes (LT) and Eoxins (EX) Aflatoxin activation and detoxification LTC4-CYSLTR mediated IL4 production

ATP-dependent chromatin remodeling Thermogenesis Hepatocellular carcinoma

DSCAM interactions

Motor proteins Vasopressin-regulated water reabsorption Salmonella infection Intraflagellar transport +1 more

Cytosolic tRNA aminoacylation

Neurexins and neuroligins

Axon guidance EPH-Ephrin signaling EPHA-mediated growth cone collapse EPH-ephrin mediated repulsion of cells +1 more

Nuclear Receptor transcription pathway

Ras signaling pathway Cellular senescence Human T-cell leukemia virus 1 infection Pathways in cancer Renal cell carcinoma Oncogene Induced Senescence +3 more

FBXL7 down-regulates AURKA during mitotic entry and in early mitosis Neddylation Antigen processing: Ubiquitination & Proteasome degradation

MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway Calcium signaling pathway PI3K-Akt signaling pathway Regulation of actin cytoskeleton Pathways in cancer Chemical carcinogenesis - receptor activation Melanoma Breast cancer Gastric cancer PI3K Cascade PIP3 activates AKT signaling Signaling by activated point mutants of FGFR1 Signaling by activated point mutants of FGFR3 FGFR3c ligand binding and activation FGFR1c ligand binding and activation FGFR2c ligand binding and activation FGFR3 mutant receptor activation Activated point mutants of FGFR2 Constitutive Signaling by Aberrant PI3K in Cancer Phospholipase C-mediated cascade: FGFR1 Phospholipase C-mediated cascade; FGFR2 Phospholipase C-mediated cascade; FGFR3 Downstream signaling of activated FGFR1 SHC-mediated cascade:FGFR1 PI-3K cascade:FGFR1 FRS-mediated FGFR1 signaling PI-3K cascade:FGFR2 SHC-mediated cascade:FGFR2 FRS-mediated FGFR2 signaling SHC-mediated cascade:FGFR3 FRS-mediated FGFR3 signaling PI-3K cascade:FGFR3 Negative regulation of FGFR1 signaling Negative regulation of FGFR2 signaling Negative regulation of FGFR3 signaling Signaling by FGFR2 in disease Signaling by FGFR1 in disease FGFRL1 modulation of FGFR1 signaling RAF/MAP kinase cascade PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling Signaling by FGFR3 point mutants in cancer +40 more

Reversal of alkylation damage by DNA dioxygenases

Mucin type O-glycan biosynthesis Other types of O-glycan biosynthesis Metabolic pathways O-linked glycosylation of mucins +1 more

Caspase-mediated cleavage of cytoskeletal proteins

Glycine, serine and threonine metabolism Arginine and proline metabolism Metabolic pathways Creatine metabolism +1 more

Regulation of Glucokinase by Glucokinase Regulatory Protein Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)

Mucin type O-glycan biosynthesis Metabolic pathways O-linked glycosylation of mucins

Ras signaling pathway Rap1 signaling pathway Calcium signaling pathway cAMP signaling pathway Neuroactive ligand-receptor interaction Circadian entrainment Long-term potentiation Glutamatergic synapse Dopaminergic synapse Alzheimer disease Amyotrophic lateral sclerosis Spinocerebellar ataxia Prion disease Pathways of neurodegeneration - multiple diseases Cocaine addiction Amphetamine addiction Nicotine addiction Alcoholism Systemic lupus erythematosus Unblocking of NMDA receptors, glutamate binding and activation Synaptic adhesion-like molecules Assembly and cell surface presentation of NMDA receptors +19 more

Ribosome biogenesis in eukaryotes

Fatty acid elongation Biosynthesis of unsaturated fatty acids Metabolic pathways Fatty acid metabolism Synthesis of very long-chain fatty acyl-CoAs +2 more

Hyaluronan biosynthesis and export

African trypanosomiasis Malaria Erythrocytes take up carbon dioxide and release oxygen Erythrocytes take up oxygen and release carbon dioxide Scavenging of heme from plasma Neutrophil degranulation Factors involved in megakaryocyte development and platelet production +4 more

GnRH secretion HCN channels

Signaling pathways regulating pluripotency of stem cells

Glycosaminoglycan biosynthesis - heparan sulfate / heparin HS-GAG biosynthesis

Serotonergic synapse Taste transduction Neurotransmitter receptors and postsynaptic signal transmission

Terpenoid backbone biosynthesis Metabolic pathways Cholesterol biosynthesis

Cytokine-cytokine receptor interaction TGF-beta signaling pathway Signaling pathways regulating pluripotency of stem cells Glycoprotein hormones +1 more

Adrenergic signaling in cardiomyocytes Cholinergic synapse Gastric acid secretion Pancreatic secretion Protein digestion and absorption Vibrio cholerae infection Voltage gated Potassium channels Phase 3 - rapid repolarisation Phase 2 - plateau phase +6 more

MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway Calcium signaling pathway PI3K-Akt signaling pathway Regulation of actin cytoskeleton Pathways in cancer Chemical carcinogenesis - receptor activation Melanoma Breast cancer Gastric cancer PI3K Cascade PIP3 activates AKT signaling Signaling by activated point mutants of FGFR1 Signaling by activated point mutants of FGFR3 FGFR3c ligand binding and activation FGFR1c ligand binding and activation FGFR2c ligand binding and activation FGFR3 mutant receptor activation Activated point mutants of FGFR2 Constitutive Signaling by Aberrant PI3K in Cancer Phospholipase C-mediated cascade: FGFR1 Phospholipase C-mediated cascade; FGFR2 Phospholipase C-mediated cascade; FGFR3 Downstream signaling of activated FGFR1 SHC-mediated cascade:FGFR1 PI-3K cascade:FGFR1 FRS-mediated FGFR1 signaling PI-3K cascade:FGFR2 SHC-mediated cascade:FGFR2 FRS-mediated FGFR2 signaling SHC-mediated cascade:FGFR3 FRS-mediated FGFR3 signaling PI-3K cascade:FGFR3 Negative regulation of FGFR1 signaling Negative regulation of FGFR2 signaling Negative regulation of FGFR3 signaling Signaling by FGFR2 in disease Signaling by FGFR1 in disease FGFRL1 modulation of FGFR1 signaling RAF/MAP kinase cascade PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling Signaling by FGFR3 point mutants in cancer +40 more

Reversal of alkylation damage by DNA dioxygenases

Glycine, serine and threonine metabolism Arginine and proline metabolism Metabolic pathways Creatine metabolism +1 more