Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
COLORECTAL CANCER	MONDO_0005575 114500 MONDO:0005575	SMAD9	Unknown	29228715 30510241 31089142 36539618 38872215	GWAS catalog	Hormone signaling TGF-beta signaling pathway Signaling pathways regulating pluripotency of stem cells +1 more
		SMARCA2	Unknown	38411962	GWAS catalog	ATP-dependent chromatin remodeling Thermogenesis Hepatocellular carcinoma +2 more
		SMC1B	Unknown	36539618	GWAS catalog	Cell cycle Oocyte meiosis
		SMC2	Unknown	34290314	GWAS catalog	Condensation of Prophase Chromosomes Condensation of Prometaphase Chromosomes
		SMCO1	Unknown	35379174	GWAS catalog	—
		SMIM14	Unknown	29228715	GWAS catalog	—
		SMIM21	Unknown	26621817	GWAS catalog	—
		SMIM30	Unknown	35512400	GWAS catalog	—
		SMIM38	Unknown	27197191 32887889	GWAS catalog	—
		SMLR1	Unknown	25192705	GWAS catalog	—
		SNAP25	Unknown	37890997	GWAS catalog	Synaptic vesicle cycle Insulin secretion Serotonin Neurotransmitter Release Cycle +10 more
		SNRK	Unknown	38538606	GWAS catalog	—
		SNTA1	Unknown	32887889	GWAS catalog	Cytoskeleton in muscle cells Hypertrophic cardiomyopathy Arrhythmogenic right ventricular cardiomyopathy +2 more
		SNTB1	Unknown	38538606	GWAS catalog	Cytoskeleton in muscle cells Hypertrophic cardiomyopathy Arrhythmogenic right ventricular cardiomyopathy +2 more
		SNX31	Unknown	34062886	GWAS catalog	—
		SORL1	Unknown	34794066	GWAS catalog	Amyloid fiber formation
		SOX6	Unknown	34594039	GWAS catalog	Deactivation of the beta-catenin transactivating complex
		SP110	Unknown	36077729	GWAS catalog	—
		SP140	Unknown	36077729	GWAS catalog	—
		SPAG16	Unknown	38538606	GWAS catalog	—
		SPAG8	Unknown	38538606	GWAS catalog	—
		SPATA21	Unknown	38411962	GWAS catalog	—
		SPECC1	Unknown	38538606	GWAS catalog	—
		SPG7	Unknown	32887889	GWAS catalog	Processing of SMDT1
		SPINK1	Unknown	38411962	GWAS catalog	—
		SPINT2	Unknown	32887889	GWAS catalog	MET Receptor Activation Signaling by MST1
		SPMIP10	Unknown	30529582	GWAS catalog	—
		SPOCK1	Unknown	38538606	GWAS catalog	—
		SPOCK2	Unknown	31826910	GWAS catalog	—
		SPPL3	Unknown	38538606	GWAS catalog	—
		SPSB2	Unknown	26965516	GWAS catalog	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
		SPTLC2	Unknown	38538606	GWAS catalog	Sphingolipid metabolism Metabolic pathways Sphingolipid signaling pathway +1 more
		SRC	Unknown	—	ClinVar, HPO	EGFR tyrosine kinase inhibitor resistance Endocrine resistance ErbB signaling pathway +92 more
		SRGAP1	Unknown	36539618	GWAS catalog	Axon guidance Rho GTPase cycle
		SSH1	Unknown	38538606	GWAS catalog	Axon guidance Regulation of actin cytoskeleton
		ST6GALNAC2	Unknown	33627384	GWAS catalog	Mucin type O-glycan biosynthesis Metabolic pathways Sialic acid metabolism +1 more
		ST8SIA2	Unknown	24743840	GWAS catalog	Sialic acid metabolism NCAM1 interactions N-Glycan antennae elongation
		STARD13	Unknown	30510241 31089142 36539618 38872215	GWAS catalog	Rho GTPase cycle
		STC1	Unknown	31826910 36539618	GWAS catalog	—
		STIM2	Unknown	34794066	GWAS catalog	Calcium signaling pathway
		STIMATE	Unknown	36539618 38872215	GWAS catalog	—
		STIMATE-MUSTN1	Unknown	36539618 38872215	GWAS catalog	—
		STK10	Unknown	33338681	GWAS catalog	Progesterone-mediated oocyte maturation Neutrophil degranulation
		STK31	Unknown	38538606	GWAS catalog	—
		STK35	Unknown	38538606	GWAS catalog	—
		STK39	Unknown	36539618	GWAS catalog	Parathyroid hormone synthesis, secretion and action
		STMN3	Unknown	32887889 34290314	GWAS catalog	—
		STN1	Unknown	32887889 34290314 37340002	GWAS catalog	Telomere C-strand synthesis initiation
		STRN3	Unknown	38411962	GWAS catalog	—
		SUCLA2	Unknown	24743840	GWAS catalog	Citrate cycle (TCA cycle) Propanoate metabolism Metabolic pathways +2 more

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Colorectal cancer

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