Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
COLORECTAL CANCER	MONDO_0005575 MONDO:0005575	SUMF1	Unknown	38538606	GWAS catalog	Lysosome Glycosphingolipid metabolism The activation of arylsulfatases
		SYT9	Unknown	29698419	GWAS catalog	Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
		TAB2	Unknown	29299148	GWAS catalog	MAPK signaling pathway NF-kappa B signaling pathway Osteoclast differentiation +33 more
		TACR1	Unknown	38411962	GWAS catalog	Calcium signaling pathway Neuroactive ligand-receptor interaction Tachykinin receptors bind tachykinins +3 more
		TANC1	Unknown	30510241 36539618	GWAS catalog	—
		TBC1D22A	Unknown	38538606	GWAS catalog	—
		TBC1D32	Unknown	38411962	GWAS catalog	—
		TBRG4	Unknown	30510241 36539618 37340002	GWAS catalog	—
		TBX3	Unknown	23266556 30510241 31826910 36539618	GWAS catalog	Signaling pathways regulating pluripotency of stem cells
		TCAF1	Unknown	35512400	GWAS catalog	—
		TCERG1L	Unknown	25866641 38538606	GWAS catalog	—
		TCF4	Unknown	29228715	GWAS catalog	Myogenesis
		TCF7L2	Unknown	24836286 26965516 29471430 30510241 30529582 31089142 31826910 32514122 36539618 37340002 38872215	GWAS catalog	Wnt signaling pathway Hippo signaling pathway Adherens junction +26 more
		TDP2	Unknown	26621817	GWAS catalog	Nonhomologous End-Joining (NHEJ)
		TDRD10	Unknown	38538606	GWAS catalog	—
		TENM2	Unknown	32887889	GWAS catalog	—
		TENM3	Unknown	38411962	GWAS catalog	—
		TENT5A	Unknown	38538606	GWAS catalog	—
		TERT	Unknown	27197191 29917119 30510241 30529582 31089142 31826910 32887889 34290314 34594039 36539618 37340002 38538606 38872215 40155373	GWAS catalog	Human papillomavirus infection Human T-cell leukemia virus 1 infection Pathways in cancer +4 more
		TESPA1	Unknown	29299148	GWAS catalog	—
		TET2	Unknown	26621817 27197191 30510241 31089142 36539618	GWAS catalog	—
		TEX29	Unknown	33893285	GWAS catalog	—
		TFEB	Unknown	26965516 30529582 31089142	GWAS catalog	Calcium signaling pathway Mitophagy - animal
		TGIF2-RAB5IF	Unknown	32887889	GWAS catalog	—
		TGM3	Unknown	34290314 37340002 38411962	GWAS catalog	—
		THADA	Unknown	32887889	GWAS catalog	tRNA modification in the nucleus and cytosol
		THEMIS	Unknown	38538606	GWAS catalog	—
		THRB	Unknown	34062886	GWAS catalog	Neuroactive ligand-receptor interaction Hormone signaling Thyroid hormone signaling pathway +2 more
		THSD4	Unknown	31826910	GWAS catalog	TGF-beta signaling pathway Defective B3GALTL causes Peters-plus syndrome (PpS) O-glycosylation of TSR domain-containing proteins
		THSD7A	Unknown	38411962	GWAS catalog	Defective B3GALTL causes Peters-plus syndrome (PpS) O-glycosylation of TSR domain-containing proteins
		TLR2	Unknown	—	ClinVar	Phagosome PI3K-Akt signaling pathway Neutrophil extracellular trap formation +30 more
		TLR5	Unknown	35512400	GWAS catalog	Toll-like receptor signaling pathway Pathogenic Escherichia coli infection Shigellosis +7 more
		TMBIM1	Unknown	28960316 29917119 38408508	GWAS catalog	Neutrophil degranulation
		TMCO5A	Unknown	25866641	GWAS catalog	—
		TMEFF2	Unknown	38538606	GWAS catalog	—
		TMEM106B	Unknown	38411962	GWAS catalog	—
		TMEM131	Unknown	38872215	GWAS catalog	—
		TMEM132D	Unknown	38411962	GWAS catalog	—
		TMEM167A	Unknown	38411962	GWAS catalog	—
		TMEM18	Unknown	36929942	GWAS catalog	—
		TMEM184C	Unknown	38411962	GWAS catalog	—
		TMEM238L	Unknown	30510241 30529582 31089142 31826910 34594039 36539618 37340002 38872215	GWAS catalog	—
		TMEM258	Unknown	24836286 26965516 29471430 30510241 30529582 36539618 37340002	GWAS catalog	N-Glycan biosynthesis Various types of N-glycan biosynthesis Protein processing in endoplasmic reticulum
		TMEM91	Unknown	24836286 26965516 27145994 30510241 31089142 36539618	GWAS catalog	—
		TMPRSS12	Unknown	38872215	GWAS catalog	—
		TMTC1	Unknown	26621817 29228715	GWAS catalog	—
		TMX1	Unknown	29299148	GWAS catalog	—
		TNFRSF19	Unknown	34794066	GWAS catalog	Cytokine-cytokine receptor interaction
		TNFSF18	Unknown	36539618	GWAS catalog	Cytokine-cytokine receptor interaction TNFs bind their physiological receptors
		TNRC6C	Unknown	38538606	GWAS catalog	Pre-NOTCH Transcription and Translation Oxidative Stress Induced Senescence Oncogene Induced Senescence +12 more
RECTUM CANCER	EFO_1000657	TCERG1L	Unknown	25866641	GWAS catalog	—
RECTUM CANCER	EFO_1000657	TMCO5A	Unknown	25866641	GWAS catalog	—

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Colorectal cancer

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