Colorectal cancer

Adherens junction Chemical carcinogenesis - reactive oxygen species Phosphorylation of CD3 and TCR zeta chains Neutrophil degranulation Negative regulation of MET activity +2 more

Type I diabetes mellitus Neutrophil degranulation

MAPK signaling pathway

Spinocerebellar ataxia Golgi Associated Vesicle Biogenesis

Starch and sucrose metabolism Metabolic pathways Necroptosis Insulin signaling pathway Glucagon signaling pathway Insulin resistance Neutrophil degranulation Glycogen breakdown (glycogenolysis) +5 more

Endocytosis Vasopressin regulates renal water homeostasis via Aquaporins

RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs

Endocytosis Neutrophil degranulation RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs +1 more

Homologous recombination HDR through Homologous Recombination (HRR) Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) Resolution of D-loop Structures through Holliday Junction Intermediates Homologous DNA Pairing and Strand Exchange Presynaptic phase of homologous DNA pairing and strand exchange Factors involved in megakaryocyte development and platelet production +4 more

Homologous recombination

Ras signaling pathway Regulation of RAS by GAPs

MAPK signaling pathway Ras signaling pathway NRAGE signals death through JNK Rho GTPase cycle G alpha (12/13) signalling events RAF/MAP kinase cascade +3 more

Spliceosome

Retinoid cycle disease events The canonical retinoid cycle in rods (twilight vision) Retinoid metabolism disease events Retinoid metabolism and transport +1 more

Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation +3 more

Antimicrobial peptides

DNA replication Base excision repair Nucleotide excision repair Mismatch repair Translesion synthesis by REV1 Recognition of DNA damage by PCNA-containing replication complex Translesion Synthesis by POLH Polymerase switching on the C-strand of the telomere Activation of ATR in response to replication stress PCNA-Dependent Long Patch Base Excision Repair Translesion synthesis by POLK Translesion synthesis by POLI Termination of translesion DNA synthesis HDR through Single Strand Annealing (SSA) HDR through Homologous Recombination (HRR) Processing of DNA double-strand break ends Presynaptic phase of homologous DNA pairing and strand exchange Gap-filling DNA repair synthesis and ligation in GG-NER Dual Incision in GG-NER Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER Regulation of TP53 Activity through Phosphorylation Polymerase switching G2/M DNA damage checkpoint +21 more

Maturity onset diabetes of the young

Rho GTPase cycle Interleukin-4 and Interleukin-13 signaling

RAB GEFs exchange GTP for GDP on RABs

RAB GEFs exchange GTP for GDP on RABs

Fanconi anemia pathway HDR through Single Strand Annealing (SSA) HDR through Homologous Recombination (HRR) Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) Resolution of D-loop Structures through Holliday Junction Intermediates Homologous DNA Pairing and Strand Exchange Processing of DNA double-strand break ends Presynaptic phase of homologous DNA pairing and strand exchange Regulation of TP53 Activity through Phosphorylation G2/M DNA damage checkpoint +7 more

Antigen processing: Ubiquitination & Proteasome degradation

Antigen processing: Ubiquitination & Proteasome degradation

Ubiquitin mediated proteolysis Human immunodeficiency virus 1 infection Neddylation Antigen processing: Ubiquitination & Proteasome degradation +1 more

mRNA surveillance pathway mRNA Capping RNA Pol II CTD phosphorylation and interaction with CE

Ribosome Coronavirus disease - COVID-19 L13a-mediated translational silencing of Ceruloplasmin expression SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) +7 more

Ribosome Coronavirus disease - COVID-19 L13a-mediated translational silencing of Ceruloplasmin expression SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Major pathway of rRNA processing in the nucleolus and cytosol Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) +10 more

Telomere Extension By Telomerase Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)

Parathyroid hormone synthesis, secretion and action Transcriptional misregulation in cancer Transcriptional regulation by RUNX2 RUNX1 regulates transcription of genes involved in differentiation of myeloid cells Regulation of RUNX2 expression and activity RUNX2 regulates osteoblast differentiation RUNX2 regulates bone development RUNX2 regulates genes involved in cell migration RUNX2 regulates genes involved in differentiation of myeloid cells +6 more

Neuroactive ligand-receptor interaction Relaxin signaling pathway G alpha (s) signalling events Relaxin receptors ADORA2B mediated anti-inflammatory cytokines production +2 more

MAPK signaling pathway Ras signaling pathway NRAGE signals death through JNK Rho GTPase cycle G alpha (12/13) signalling events RAF/MAP kinase cascade +3 more

Starch and sucrose metabolism Metabolic pathways Necroptosis Insulin signaling pathway Glucagon signaling pathway Insulin resistance Neutrophil degranulation Glycogen breakdown (glycogenolysis) +5 more