Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
colon adenocarcinoma	MONDO_0002271	GPC5	Unknown	22810696 29937994 26416732 26336987 25957691 25344691 24755471 22895193	Open Targets	A tetrasaccharide linker sequence is required for GAG synthesis HS-GAG biosynthesis HS-GAG degradation +7 more
		GPHN	Unknown	22810696 27612425 29937994 26416732 25957691 26109429 25344691 24755471 22895193	Open Targets	Folate biosynthesis Metabolic pathways Biosynthesis of cofactors +2 more
		GRIN2A	Unknown	22810696 29967250 26071483 26764183 29937994 27612425 21203531 26416732 29316426 23856246 28465371 25957691 26336987 30239619 32375028 25344691 22895193 28481359	Open Targets	Ras signaling pathway Rap1 signaling pathway Calcium signaling pathway +19 more
		GRM3	Unknown	22810696 26071483 27612425 29937994 21203531 26416732 32375028 25344691 24755471 22895193	Open Targets	Phospholipase D signaling pathway Neuroactive ligand-receptor interaction Glutamatergic synapse +3 more
		GSK3B	Unknown	22810696 23856246 25957691 25344691 22895193 28481359	Open Targets	EGFR tyrosine kinase inhibitor resistance ErbB signaling pathway Chemokine signaling pathway +59 more
		GTF2I	Unknown	25957691 24755471 26071483 25344691	Open Targets	Basal transcription factors cGMP-PKG signaling pathway
		H3-3A	Unknown	23758177 24943349 28481359	Open Targets	Neutrophil extracellular trap formation Alcoholism Shigellosis +18 more
		H3-3B	Unknown	25957691 24755471 22895193 25344691 22810696	Open Targets	Neutrophil extracellular trap formation Alcoholism Shigellosis +18 more
		H3C2	Unknown	28481359 26416732 22895193 25589621 25957691	Open Targets	Neutrophil extracellular trap formation Alcoholism Shigellosis +27 more
		H4C9	Unknown	22895193 29937994	Open Targets	Neutrophil extracellular trap formation Alcoholism Viral carcinogenesis +33 more
		HERPUD1	Unknown	22810696 26071483 29937994 25957691 25344691 24755471 22895193	Open Targets	Protein processing in endoplasmic reticulum ATF4 activates genes in response to endoplasmic reticulum stress
		HGF	Unknown	22810696 29967250 26071483 26764183 26416732 29316426 25957691 26109429 25344691 38725616 24755471 22895193 28481359	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +29 more
		HIF1A	Unknown	29967250 29937994 26416732 23856246 25344691 29844865 24755471 22895193	Open Targets	HIF-1 signaling pathway Mitophagy - animal Autophagy - animal +19 more
		HIP1	Unknown	22810696 26071483 29937994 26416732 26336987 23856246 25957691 30239619 32375028 25344691 38725616 24755471 22895193	Open Targets	Huntington disease Pathways of neurodegeneration - multiple diseases Clathrin-mediated endocytosis
		HLA-A	Unknown	22810696 27302369 29316426 26109429 25344691 28481359	Open Targets	Endocytosis Phagosome Cellular senescence +25 more
		HLF	Unknown	22810696 26071483 24943349 25957691 25344691 24755471 22895193	Open Targets	—
		HMGA1	Unknown	30239619	Open Targets	Integration of provirus 2-LTR circle formation Integration of viral DNA into host genomic DNA +4 more
		HMGA2	Unknown	22810696 30239619 26071483 25957691 29937994	Open Targets	Transcriptional misregulation in cancer MicroRNAs in cancer Formation of Senescence-Associated Heterochromatin Foci (SAHF)
		HNF1A	Unknown	22810696 26071483 29937994 26416732 27756406 25957691 19503063 25344691 29844865 38725616 24755471 22895193 28481359	Open Targets	Maturity onset diabetes of the young
		HNRNPA2B1	Unknown	22810696 29937994 26416732 25957691 25344691 31336886 22895193	Open Targets	Amyotrophic lateral sclerosis mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA +1 more
		HOOK3	Unknown	22810696 29967250 26071483 29937994 26416732 23856246 25957691 32375028 25344691 24755471 22895193	Open Targets	Motor proteins
		HOXA11	Unknown	22810696 23856246 25957691 25344691	Open Targets	Transcriptional misregulation in cancer
		HOXA13	Unknown	26416732 22895193 25344691 26071483	Open Targets	—
		HOXA9	Unknown	25344691 25957691	Open Targets	Transcriptional misregulation in cancer
		HOXC11	Unknown	26416732 26764183 25344691 25957691	Open Targets	—
		HOXC13	Unknown	22810696 32375028 22895193 25957691 26336987	Open Targets	—
		HOXD11	Unknown	22810696 26416732 23856246 25957691 25344691 22895193	Open Targets	—
		HRAS	Unknown	34680263 26071483 26561417 26416732 27756406 28978093 25344691 29844865 36142641 25617745 28481359	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +134 more
		HSP90AA1	Unknown	22810696 26071483 29937994 25957691 25344691 22895193	Open Targets	Protein processing in endoplasmic reticulum PI3K-Akt signaling pathway Necroptosis +56 more
		HSP90AB1	Unknown	22810696 29967250 26336987 23856246 25344691 29844865 22895193	Open Targets	Protein processing in endoplasmic reticulum PI3K-Akt signaling pathway Necroptosis +26 more
		ID3	Unknown	25957691	Open Targets	TGF-beta signaling pathway Signaling pathways regulating pluripotency of stem cells NGF-stimulated transcription
		IDH1	Unknown	29967250 28481359 34680263 26416732 25029120 27756406 25957691 29316426 25344691 26968814 29844865 25496513 19117336	Open Targets	Citrate cycle (TCA cycle) Glutathione metabolism Metabolic pathways +9 more
		IDH2	Unknown	22810696 29316426 25344691 24755471 22895193 28481359	Open Targets	Citrate cycle (TCA cycle) Glutathione metabolism Metabolic pathways +7 more
		IGF2BP2	Unknown	22810696 26071483 29937994 23856246 25344691 24755471 22895193	Open Targets	Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA
		IKBKB	Unknown	22810696 29937994 26416732 25957691 25344691 29844865 24755471 22895193	Open Targets	Antifolate resistance MAPK signaling pathway Ras signaling pathway +79 more
		IKZF1	Unknown	22810696 26071483 27612425 29937994 26416732 29316426 25957691 30239619 25344691 29844865 24755471 22895193 28481359	Open Targets	—
		IKZF3	Unknown	22810696 24755471 22895193 25957691 29937994	Open Targets	—
		IL2	Unknown	22810696 25344691 29937994	Open Targets	Cytokine-cytokine receptor interaction Viral protein interaction with cytokine and cytokine receptor PI3K-Akt signaling pathway +21 more
		IL21R	Unknown	22810696 26071483 25344691 29844865 24755471 22895193	Open Targets	Cytokine-cytokine receptor interaction JAK-STAT signaling pathway Th17 cell differentiation +2 more
		IL6ST	Unknown	22810696 29665843 29937994 23856246 25957691 26109429 32375028 16959974 25344691 29844865 24755471 22895193	Open Targets	Cytokine-cytokine receptor interaction Viral protein interaction with cytokine and cytokine receptor Signaling pathways regulating pluripotency of stem cells +12 more
		IL7R	Unknown	29937994 26416732 29316426 25589621 25957691 25344691 29844865 38725616 22895193 28481359	Open Targets	Cytokine-cytokine receptor interaction FoxO signaling pathway PI3K-Akt signaling pathway +7 more
		IRF4	Unknown	22810696 26071483 29937994 25957691 30239619 25344691 22895193 28481359	Open Targets	Th17 cell differentiation Interleukin-4 and Interleukin-13 signaling Interferon gamma signaling +1 more
		IRS4	Unknown	22810696 26071483 26764183 26416732 25957691 25344691 16959974 24755471 22895193	Open Targets	cGMP-PKG signaling pathway FoxO signaling pathway Hormone signaling +11 more
		ISX	Unknown	24755471 22895193 23856246	Open Targets	—
		ITGAV	Unknown	22810696 29937994 21203531 26416732 23856246 25957691 30239619 32375028 25344691 24755471 22895193	Open Targets	Hormone signaling Phagosome Efferocytosis +26 more
		ITK	Unknown	22810696 26416732 25344691 29937994	Open Targets	Chemokine signaling pathway T cell receptor signaling pathway Leukocyte transendothelial migration +2 more
		JAK1	Unknown	29967250 34680263 26071483 26764183 29937994 29316426 23856246 25957691 26109429 25344691 24755471 22895193 28481359	Open Targets	EGFR tyrosine kinase inhibitor resistance PI3K-Akt signaling pathway Necroptosis +48 more
		JAK2	Unknown	29967250 27023146 24755471 34680263 22810696 29937994 23856246 25957691 25344691 29844865 25617745 28481359	Open Targets	EGFR tyrosine kinase inhibitor resistance Chemokine signaling pathway Hormone signaling +51 more
		JAK3	Unknown	26071483 25617745 29937994 26416732 29316426 25589621 27756406 28145097 26109429 30239619 25344691 29844865 38725616 24755471 22895193 28481359	Open Targets	Chemokine signaling pathway PI3K-Akt signaling pathway Necroptosis +21 more
		JAZF1	Unknown	22810696 22895193 25344691 29937994	Open Targets	—

«‹1…5 678 9…15 ›»

Colon adenocarcinoma

Bookmark This Disease