Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
BREAST CANCER	MONDO_0007254	EXO1	Unknown	25751625 29059683	GWAS catalog	Mismatch repair Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) HDR through Single Strand Annealing (SSA) +8 more
		EXOC3	Unknown	29059683	GWAS catalog	Insulin processing VxPx cargo-targeting to cilium
		EXT1	Unknown	29059683	GWAS catalog	Glycosaminoglycan biosynthesis - heparan sulfate / heparin Metabolic pathways HS-GAG biosynthesis +2 more
		FAM13B	Unknown	38538606	GWAS catalog	Rho GTPase cycle
		FAM177A1	Unknown	37340002	GWAS catalog	—
		FAM185A	Unknown	37380357	GWAS catalog	—
		FAM20A	Unknown	29059683	GWAS catalog	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
		FAM227B	Unknown	32887889 38538606	GWAS catalog	—
		FAM72B	Unknown	38538606	GWAS catalog	—
		FAM83B	Unknown	29059683 37380357	GWAS catalog	—
		FAM91A1	Unknown	29058716 32139696	GWAS catalog	—
		FAR2	Unknown	31757997	GWAS catalog	Peroxisome Wax biosynthesis
		FBN1	Unknown	17903305	GWAS catalog	TGF-beta signaling pathway Cytoskeleton in muscle cells Degradation of the extracellular matrix +5 more
		FBN2	Unknown	29059683	GWAS catalog	Cytoskeleton in muscle cells Degradation of the extracellular matrix Elastic fibre formation +1 more
		FBXL13	Unknown	29059683 37380357	GWAS catalog	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
		FBXO33	Unknown	38538606	GWAS catalog	—
		FDPS	Unknown	29059683	GWAS catalog	Terpenoid backbone biosynthesis Metabolic pathways Influenza A +3 more
		FEZF1	Unknown	37380357	GWAS catalog	—
		FGF10	Unknown	29059683 32424353	GWAS catalog	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +29 more
		FILIP1L	Unknown	29059683 32139696	GWAS catalog	—
		FKBP8	Unknown	29059683	GWAS catalog	Mitophagy - animal Ub-specific processing proteases
		FLACC1	Unknown	29059683 32139696 32887889 34594039 37340002 38538606	GWAS catalog	—
		FLNB	Unknown	38538606	GWAS catalog	Focal adhesion ISG15 antiviral mechanism
		FNDC3B	Unknown	29059683	GWAS catalog	—
		FOXK2	Unknown	29059683	GWAS catalog	Polycomb repressive complex UCH proteinases
		FOXL2NB	Unknown	29059683	GWAS catalog	—
		FOXN3	Unknown	29059683	GWAS catalog	—
		FOXP1	Unknown	29059683 32139696 36819030	GWAS catalog	MicroRNAs in cancer Transcriptional regulation of pluripotent stem cells
		FOXP2	Unknown	37380357	GWAS catalog	—
		FOXQ1	Unknown	23535729 25751625 29059683	GWAS catalog	—
		FRMD4A	Unknown	29059683	GWAS catalog	—
		FST	Unknown	29059683	GWAS catalog	TGF-beta signaling pathway Antagonism of Activin by Follistatin
		FTO	Unknown	23535729 23535733 25751625 27117709 29059683 32139696 32887889 34594039 37340002 37380357 38538606 38741014	GWAS catalog	Reversal of alkylation damage by DNA dioxygenases
		GAB1	Unknown	29059683	GWAS catalog	EGFR tyrosine kinase inhibitor resistance ErbB signaling pathway Ras signaling pathway +32 more
		GABARAPL2	Unknown	38538606	GWAS catalog	FoxO signaling pathway Autophagy - other Mitophagy - animal +5 more
		GALC	Unknown	22923054	GWAS catalog	Sphingolipid metabolism Metabolic pathways Lysosome +1 more
		GALNTL5	Unknown	34290314	GWAS catalog	Mucin type O-glycan biosynthesis Other types of O-glycan biosynthesis Metabolic pathways +1 more
		GAREM1	Unknown	29059683 32139696 38741014	GWAS catalog	—
		GASK1A	Unknown	38538606	GWAS catalog	—
		GATAD2A	Unknown	29059683 32139696 36819030	GWAS catalog	ATP-dependent chromatin remodeling HDACs deacetylate histones Regulation of TP53 Activity through Acetylation +2 more
		GBGT1	Unknown	37636041	GWAS catalog	Glycosphingolipid biosynthesis - globo and isoglobo series Metabolic pathways
		GDI2	Unknown	20453838	GWAS catalog	Rho GTPase cycle Neutrophil degranulation RAB GEFs exchange GTP for GDP on RABs
		GFOD1	Unknown	40229280	GWAS catalog	—
		GID4	Unknown	37380357	GWAS catalog	—
		GIPR	Unknown	29059683 32139696 37380357	GWAS catalog	cAMP signaling pathway Neuroactive ligand-receptor interaction Hormone signaling +3 more
		GLI2	Unknown	32887889	GWAS catalog	Hedgehog signaling pathway Hippo signaling pathway Pathways in cancer +4 more
		GNAO1	Unknown	37380357	GWAS catalog	Rap1 signaling pathway Hormone signaling Circadian entrainment +21 more
		GNG2	Unknown	29059683	GWAS catalog	Ras signaling pathway Chemokine signaling pathway Hormone signaling +43 more
		GON4L	Unknown	37636041	GWAS catalog	—
		GPAT3	Unknown	29059683	GWAS catalog	Glycerolipid metabolism Glycerophospholipid metabolism Metabolic pathways +1 more
BREAST CARCINOMA	EFO_0000305	EXO1	Unknown	25751625 29059683 35803233	GWAS catalog	Mismatch repair Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) HDR through Single Strand Annealing (SSA) +8 more
		EXOC3	Unknown	29059683	GWAS catalog	Insulin processing VxPx cargo-targeting to cilium
		EXT1	Unknown	29059683	GWAS catalog	Glycosaminoglycan biosynthesis - heparan sulfate / heparin Metabolic pathways HS-GAG biosynthesis +2 more
		FAM13B	Unknown	38538606	GWAS catalog	Rho GTPase cycle
		FAM177A1	Unknown	37340002	GWAS catalog	—
		FAM20A	Unknown	29059683	GWAS catalog	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
		FAM227B	Unknown	32887889 38538606	GWAS catalog	—
		FAM72B	Unknown	38538606	GWAS catalog	—
		FAM83B	Unknown	29059683	GWAS catalog	—
		FAM91A1	Unknown	29058716 32139696	GWAS catalog	—
		FAR2	Unknown	31757997	GWAS catalog	Peroxisome Wax biosynthesis
		FBN1	Unknown	17903305	GWAS catalog	TGF-beta signaling pathway Cytoskeleton in muscle cells Degradation of the extracellular matrix +5 more
		FBN2	Unknown	29059683	GWAS catalog	Cytoskeleton in muscle cells Degradation of the extracellular matrix Elastic fibre formation +1 more
		FBXL13	Unknown	29059683	GWAS catalog	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
		FBXO33	Unknown	38538606	GWAS catalog	—
		FDPS	Unknown	29059683	GWAS catalog	Terpenoid backbone biosynthesis Metabolic pathways Influenza A +3 more
		FGF10	Unknown	29059683 32424353	GWAS catalog	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +29 more
		FILIP1L	Unknown	29059683 32139696	GWAS catalog	—
		FKBP8	Unknown	29059683	GWAS catalog	Mitophagy - animal Ub-specific processing proteases
		FLACC1	Unknown	29058716 29059683 32139696 32887889 34594039 37340002 38538606	GWAS catalog	—
		FLNB	Unknown	38538606	GWAS catalog	Focal adhesion ISG15 antiviral mechanism
		FNDC3B	Unknown	29059683	GWAS catalog	—
		FOXK2	Unknown	29059683	GWAS catalog	Polycomb repressive complex UCH proteinases
		FOXL2NB	Unknown	29059683	GWAS catalog	—
		FOXN3	Unknown	29059683	GWAS catalog	—
		FOXP1	Unknown	29059683 32139696 34290314 37467357	GWAS catalog	MicroRNAs in cancer Transcriptional regulation of pluripotent stem cells
		FOXQ1	Unknown	23535729 25751625 29059683	GWAS catalog	—
		FRMD4A	Unknown	29059683	GWAS catalog	—
		FST	Unknown	29059683	GWAS catalog	TGF-beta signaling pathway Antagonism of Activin by Follistatin
		FTO	Unknown	23535729 23535733 25751625 27117709 29058716 29059683 32139696 32887889 34594039 35414113 37340002 38538606 38741014	GWAS catalog	Reversal of alkylation damage by DNA dioxygenases
		GAB1	Unknown	29059683	GWAS catalog	EGFR tyrosine kinase inhibitor resistance ErbB signaling pathway Ras signaling pathway +32 more
		GABARAPL2	Unknown	38538606	GWAS catalog	FoxO signaling pathway Autophagy - other Mitophagy - animal +5 more
		GALC	Unknown	22923054	GWAS catalog	Sphingolipid metabolism Metabolic pathways Lysosome +1 more
		GALNTL5	Unknown	34290314	GWAS catalog	Mucin type O-glycan biosynthesis Other types of O-glycan biosynthesis Metabolic pathways +1 more
		GAREM1	Unknown	29058716 29059683 32139696 38741014	GWAS catalog	—
		GASK1A	Unknown	38538606	GWAS catalog	—
		GATAD2A	Unknown	27432226 29059683 32139696 37467357	GWAS catalog	ATP-dependent chromatin remodeling HDACs deacetylate histones Regulation of TP53 Activity through Acetylation +2 more
		GDI2	Unknown	20453838	GWAS catalog	Rho GTPase cycle Neutrophil degranulation RAB GEFs exchange GTP for GDP on RABs
		GFOD1	Unknown	40229280	GWAS catalog	—
		GIPR	Unknown	29059683 32139696	GWAS catalog	cAMP signaling pathway Neuroactive ligand-receptor interaction Hormone signaling +3 more
		GLI2	Unknown	32887889	GWAS catalog	Hedgehog signaling pathway Hippo signaling pathway Pathways in cancer +4 more
		GNAO1	Unknown	35803233	GWAS catalog	Rap1 signaling pathway Hormone signaling Circadian entrainment +21 more
		GNG2	Unknown	29059683	GWAS catalog	Ras signaling pathway Chemokine signaling pathway Hormone signaling +43 more
		GPAT3	Unknown	29059683	GWAS catalog	Glycerolipid metabolism Glycerophospholipid metabolism Metabolic pathways +1 more

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Breast cancer

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