Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
BIPOLAR DISORDER	MONDO_0004985 C0005586 MESH:D001714	DLC1	Unknown	22688191	GWAS catalog	Rho GTPase cycle
		DLG2	Unknown	—	Disgenet	Hippo signaling pathway Tight junction Human papillomavirus infection +3 more
		DLG3	Unknown	—	Disgenet	Hippo signaling pathway Tight junction Human papillomavirus infection +5 more
		DLG4	Unknown	—	Disgenet	Hippo signaling pathway Glutamatergic synapse Huntington disease +10 more
		DLGAP2	Unknown	31043756	GWAS catalog	—
		DLX1	Unknown	—	Disgenet	—
		DMD	Unknown	20889312	GWAS catalog	Cytoskeleton in muscle cells Hypertrophic cardiomyopathy Arrhythmogenic right ventricular cardiomyopathy +3 more
		DMTF1	Unknown	20351715	GWAS catalog	—
		DNAH8	Unknown	—	Disgenet	Motor proteins Amyotrophic lateral sclerosis Huntington disease +1 more
		DNAJB1	Unknown	—	Disgenet	Protein processing in endoplasmic reticulum Influenza A Regulation of HSF1-mediated heat shock response +4 more
		DNAJB4	Unknown	38858783	GWAS catalog	—
		DNAJB7	Unknown	34159505	GWAS catalog	—
		DNAJC7	Unknown	34099189	GWAS catalog	Regulation of HSF1-mediated heat shock response
		DNMT1	Unknown	—	Disgenet	Cysteine and methionine metabolism Metabolic pathways MicroRNAs in cancer +2 more
		DOCK2	Unknown	33169155 34002096 38154582	GWAS catalog	Chemokine signaling pathway Nef and signal transduction Neutrophil degranulation +1 more
		DOCK6	Unknown	20889312	GWAS catalog	Factors involved in megakaryocyte development and platelet production
		DOCK9	Unknown	—	Disgenet	Factors involved in megakaryocyte development and platelet production
		DOK5	Unknown	—	Disgenet	RET signaling
		DORIP1	Unknown	—	Disgenet	—
		DPP10	Unknown	21254220	GWAS catalog	—
		DPY19L3	Unknown	19488044	GWAS catalog	—
		DPYSL2	Unknown	—	Disgenet	Axon guidance CRMPs in Sema3A signaling Recycling pathway of L1
		DRD1	Unknown	19153942	CTD, Disgenet	Calcium signaling pathway cAMP signaling pathway Neuroactive ligand-receptor interaction +11 more
		DRD2	Unknown	31835028 31926635 32606422 33263727 33479212 34159505	Disgenet, GWAS catalog	Rap1 signaling pathway cAMP signaling pathway Neuroactive ligand-receptor interaction +7 more
		DRD3	Unknown	—	Disgenet	Neuroactive ligand-receptor interaction Hormone signaling Dopaminergic synapse +2 more
		DRD4	Unknown	—	Disgenet	Neuroactive ligand-receptor interaction Hormone signaling Dopaminergic synapse +2 more
		DRD5	Unknown	14708030	CTD, Disgenet	Calcium signaling pathway cAMP signaling pathway Neuroactive ligand-receptor interaction +5 more
		DSCAM	Unknown	—	Disgenet	DSCAM interactions
		DTNBP1	Unknown	—	Disgenet	Golgi Associated Vesicle Biogenesis
		DUSP6	Unknown	—	Disgenet	MAPK signaling pathway Transcriptional misregulation in cancer Acute myeloid leukemia +3 more
		DYNLRB1	Unknown	38858783	GWAS catalog	Motor proteins Salmonella infection Intraflagellar transport
		E2F7	Unknown	34099189	GWAS catalog	TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest
		EBNA1BP2	Unknown	24322204	GWAS catalog	Major pathway of rRNA processing in the nucleolus and cytosol
		EEF1A2	Unknown	31043756	GWAS catalog	Nucleocytoplasmic transport Legionellosis Leishmaniasis
		EFCAB10	Unknown	24322204	GWAS catalog	—
		EFNA5	Unknown	20889312 31926635	GWAS catalog	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +6 more
		EFNB1	Unknown	33479212	GWAS catalog	Axon guidance EPH-Ephrin signaling EPHB-mediated forward signaling +2 more
		EGFR	Unknown	26503763	GWAS catalog	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Virion - Hepatitis viruses +79 more
		EGR2	Unknown	—	Disgenet	C-type lectin receptor signaling pathway Hepatitis B Human T-cell leukemia virus 1 infection +3 more
		EGR3	Unknown	—	Disgenet	C-type lectin receptor signaling pathway Hepatitis B Viral carcinogenesis +1 more
		EHHADH	Unknown	—	Disgenet	Fatty acid degradation Valine, leucine and isoleucine degradation Lysine degradation +10 more
		EMILIN3	Unknown	31926635	GWAS catalog	Molecules associated with elastic fibres
		ENOX1	Unknown	31835028 31926635	GWAS catalog	—
		ENTREP1	Unknown	22925353	GWAS catalog	—
		EPHX2	Unknown	31835028	GWAS catalog	Arachidonic acid metabolism Metabolic pathways Peroxisome +5 more
		ERBB2	Unknown	27329760	GWAS catalog	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +48 more
		ERBB3	Unknown	—	Disgenet	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway ErbB signaling pathway +19 more
		ERBB4	Unknown	40465716	Disgenet, GWAS catalog	MAPK signaling pathway ErbB signaling pathway Calcium signaling pathway +22 more
		ERC2	Unknown	21057379	GWAS catalog	—
		ERCC4	Unknown	29121268 31835028 31926635 33479212	GWAS catalog	Nucleotide excision repair Fanconi anemia pathway HDR through Single Strand Annealing (SSA) +4 more
BIPOLAR I DISORDER	EFO_0009963	EEF1A2	Unknown	31043756	GWAS catalog	Nucleocytoplasmic transport Legionellosis Leishmaniasis
BIPOLAR I DISORDER, MOST RECENT EPISODE MANIC	C0024713	DRD1	Unknown	—	Disgenet	Calcium signaling pathway cAMP signaling pathway Neuroactive ligand-receptor interaction +11 more
BIPOLAR I DISORDER, MOST RECENT EPISODE MANIC	C0024713	DRD5	Unknown	—	Disgenet	Calcium signaling pathway cAMP signaling pathway Neuroactive ligand-receptor interaction +5 more
MIXED BIPOLAR I DISORDER	C0236780	DRD1	Unknown	—	Disgenet	Calcium signaling pathway cAMP signaling pathway Neuroactive ligand-receptor interaction +11 more
MIXED BIPOLAR I DISORDER	C0236780	DRD5	Unknown	—	Disgenet	Calcium signaling pathway cAMP signaling pathway Neuroactive ligand-receptor interaction +5 more

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