Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
BIPOLAR DISORDER	MONDO_0004985 C0005586 MESH:D001714	CHRM3	Unknown	33479212	GWAS catalog	Calcium signaling pathway Neuroactive ligand-receptor interaction Cholinergic synapse +10 more
		CHRNA2	Unknown	—	Disgenet	Neuroactive ligand-receptor interaction Highly calcium permeable postsynaptic nicotinic acetylcholine receptors Highly calcium permeable nicotinic acetylcholine receptors
		CHRNA3	Unknown	31835028 32606422 33479212	GWAS catalog	Neuroactive ligand-receptor interaction Cholinergic synapse Chemical carcinogenesis - receptor activation +3 more
		CHRNA5	Unknown	34159505	GWAS catalog	Neuroactive ligand-receptor interaction Highly calcium permeable postsynaptic nicotinic acetylcholine receptors Highly calcium permeable nicotinic acetylcholine receptors
		CHRNA6	Unknown	38858783	Disgenet, GWAS catalog	Neuroactive ligand-receptor interaction Cholinergic synapse Nicotine addiction +2 more
		CHRNA7	Unknown	—	Disgenet	Calcium signaling pathway Neuroactive ligand-receptor interaction Cholinergic synapse +5 more
		CHRNB3	Unknown	—	Disgenet	Neuroactive ligand-receptor interaction Highly calcium permeable postsynaptic nicotinic acetylcholine receptors Highly calcium permeable nicotinic acetylcholine receptors
		CHST3	Unknown	30217971	GWAS catalog	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate Chondroitin sulfate biosynthesis Defective CHST3 causes SEDCJD
		CLASP1	Unknown	31579629	GWAS catalog	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion +10 more
		CLCN2	Unknown	—	Disgenet	Mineral absorption Stimuli-sensing channels
		CLDN11	Unknown	20889312	GWAS catalog	Virion - Hepatitis viruses Cell adhesion molecules Tight junction +3 more
		CLEC10A	Unknown	—	Disgenet	Dectin-2 family
		CLEC17A	Unknown	23453885	GWAS catalog	—
		CLHC1	Unknown	24322204	GWAS catalog	—
		CLN3	Unknown	31754094	GWAS catalog	Lysosome
		CLOCK	Unknown	—	Disgenet	Circadian rhythm Dopaminergic synapse BMAL1:CLOCK,NPAS2 activates circadian gene expression
		CLTA	Unknown	25781172	GWAS catalog	Lysosome Endocytosis Synaptic vesicle cycle +18 more
		CMKLR1	Unknown	22688191	GWAS catalog	Class A/1 (Rhodopsin-like receptors)
		CMTM8	Unknown	18711365 21254220	GWAS catalog	—
		CMTR2	Unknown	34099189	GWAS catalog	—
		CMYA5	Unknown	20889312	GWAS catalog	—
		CNKSR2	Unknown	31043756 33479212	GWAS catalog	MAP2K and MAPK activation Signaling by moderate kinase activity BRAF mutants Signaling by high-kinase activity BRAF mutants +3 more
		CNNM2	Unknown	23453885 31926635 33479212	GWAS catalog	—
		CNNM3	Unknown	31043756 38154582	GWAS catalog	—
		CNNM4	Unknown	18711365 20351715 21926972 31835028 32606422 33479212 33686288 34002096 34159505	GWAS catalog	—
		CNR1	Unknown	—	Disgenet	Rap1 signaling pathway Neuroactive ligand-receptor interaction Thermogenesis +3 more
		CNR2	Unknown	—	Disgenet	Neuroactive ligand-receptor interaction Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events
		CNTN1	Unknown	22925353	GWAS catalog	Cell adhesion molecules
		CNTN4	Unknown	31835028 32606422 33479212 34159505	Disgenet, GWAS catalog	Post-translational modification: synthesis of GPI-anchored proteins
		CNTN5	Unknown	20889312 31926635 39024449	GWAS catalog	Post-translational modification: synthesis of GPI-anchored proteins
		CNTN6	Unknown	—	Disgenet	—
		CNTNAP2	Unknown	20889312 31043756	Disgenet, GWAS catalog	Cell adhesion molecules
		COA8	Unknown	33479212 34159505	GWAS catalog	—
		COL22A1	Unknown	33893285	GWAS catalog	Protein digestion and absorption Collagen biosynthesis and modifying enzymes Collagen chain trimerization
		COL28A1	Unknown	20889312	GWAS catalog	Protein digestion and absorption Collagen biosynthesis and modifying enzymes Collagen chain trimerization
		COL2A1	Unknown	20889312	GWAS catalog	PI3K-Akt signaling pathway Focal adhesion ECM-receptor interaction +14 more
		COL4A2	Unknown	20889312	GWAS catalog	PI3K-Akt signaling pathway Focal adhesion ECM-receptor interaction +20 more
		COMMD10	Unknown	22688191	GWAS catalog	Neddylation
		COMT	Unknown	11772685	CTD, Disgenet	Steroid hormone biosynthesis Tyrosine metabolism Metabolic pathways +4 more
		COP1	Unknown	31926635	GWAS catalog	p53 signaling pathway Ubiquitin mediated proteolysis Autodegradation of the E3 ubiquitin ligase COP1 +1 more
		COX6A1	Unknown	31043756	GWAS catalog	Oxidative phosphorylation Metabolic pathways Cardiac muscle contraction +12 more
		CPLX1	Unknown	14708030	CTD, Disgenet	Synaptic vesicle cycle Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle +4 more
		CPLX2	Unknown	14708030	CTD, Disgenet	Synaptic vesicle cycle
		CPNE8	Unknown	28115744	GWAS catalog	—
		CRACDL	Unknown	19416921	GWAS catalog	—
		CRBN	Unknown	18711365 20351715	GWAS catalog	—
		CREB1	Unknown	—	Disgenet	cGMP-PKG signaling pathway cAMP signaling pathway Efferocytosis +53 more
		CREB5	Unknown	33686288	GWAS catalog	cGMP-PKG signaling pathway cAMP signaling pathway PI3K-Akt signaling pathway +31 more
		CRH	Unknown	—	Disgenet	cAMP signaling pathway Neuroactive ligand-receptor interaction Hormone signaling +6 more
		CRHR1	Unknown	—	Disgenet	cAMP signaling pathway Neuroactive ligand-receptor interaction Hormone signaling +5 more
BIPOLAR I DISORDER	EFO_0009963	CNNM3	Unknown	31043756	GWAS catalog	—
BIPOLAR I DISORDER	EFO_0009963	CNNM4	Unknown	34002096	GWAS catalog	—
BIPOLAR I DISORDER, MOST RECENT EPISODE MANIC	C0024713	CHRNB3	Unknown	—	Disgenet	Neuroactive ligand-receptor interaction Highly calcium permeable postsynaptic nicotinic acetylcholine receptors Highly calcium permeable nicotinic acetylcholine receptors
		COMT	Unknown	—	Disgenet	Steroid hormone biosynthesis Tyrosine metabolism Metabolic pathways +4 more
		CPLX1	Unknown	—	Disgenet	Synaptic vesicle cycle Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle +4 more
		CPLX2	Unknown	—	Disgenet	Synaptic vesicle cycle
MIXED BIPOLAR I DISORDER	C0236780	CHRNB3	Unknown	—	Disgenet	Neuroactive ligand-receptor interaction Highly calcium permeable postsynaptic nicotinic acetylcholine receptors Highly calcium permeable nicotinic acetylcholine receptors
		COMT	Unknown	—	Disgenet	Steroid hormone biosynthesis Tyrosine metabolism Metabolic pathways +4 more
		CPLX1	Unknown	—	Disgenet	Synaptic vesicle cycle Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle +4 more
		CPLX2	Unknown	—	Disgenet	Synaptic vesicle cycle

«‹1…3 456 7…25 ›»

Bipolar disorder

Bookmark This Disease