Bipolar disorder

Synaptic vesicle cycle Retrograde endocannabinoid signaling Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle GABA synthesis, release, reuptake and degradation +5 more

RAB GEFs exchange GTP for GDP on RABs

COPI-dependent Golgi-to-ER retrograde traffic

SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Formation of Incision Complex in GG-NER Antigen processing: Ubiquitination & Proteasome degradation

Endocytosis Downregulation of ERBB2:ERBB3 signaling Antigen processing: Ubiquitination & Proteasome degradation

mRNA surveillance pathway mRNA Capping RNA Pol II CTD phosphorylation and interaction with CE

Wnt signaling pathway WNT5A-dependent internalization of FZD2, FZD5 and ROR2

Wnt signaling pathway WNT5A-dependent internalization of FZD2, FZD5 and ROR2

Th17 cell differentiation Circadian rhythm Spinocerebellar ataxia Inflammatory bowel disease RORA activates gene expression PPARA activates gene expression Nuclear Receptor transcription pathway Circadian Clock SUMOylation of intracellular receptors Interleukin-4 and Interleukin-13 signaling +7 more

DNA replication Nucleotide excision repair Mismatch repair Homologous recombination Fanconi anemia pathway Translesion synthesis by REV1 Recognition of DNA damage by PCNA-containing replication complex Translesion Synthesis by POLH Removal of the Flap Intermediate from the C-strand Activation of ATR in response to replication stress SUMOylation of DNA damage response and repair proteins Regulation of HSF1-mediated heat shock response HSF1 activation Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) PCNA-Dependent Long Patch Base Excision Repair Translesion synthesis by POLK Translesion synthesis by POLI Termination of translesion DNA synthesis HDR through Single Strand Annealing (SSA) HDR through Homologous Recombination (HRR) Processing of DNA double-strand break ends Presynaptic phase of homologous DNA pairing and strand exchange Formation of Incision Complex in GG-NER Gap-filling DNA repair synthesis and ligation in GG-NER Dual Incision in GG-NER Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER Fanconi Anemia Pathway Regulation of TP53 Activity through Phosphorylation Activation of the pre-replicative complex Removal of the Flap Intermediate G2/M DNA damage checkpoint +30 more

Hedgehog 'off' state Anchoring of the basal body to the plasma membrane

Ribosome Coronavirus disease - COVID-19 L13a-mediated translational silencing of Ceruloplasmin expression SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) +7 more

RNA polymerase II transcribes snRNA genes

Regulation of HSF1-mediated heat shock response

MAPK signaling pathway Oocyte meiosis mTOR signaling pathway Thermogenesis Long-term potentiation Neurotrophin signaling pathway Progesterone-mediated oocyte maturation Insulin resistance Yersinia infection Chemical carcinogenesis - receptor activation ERK/MAPK targets CREB phosphorylation Senescence-Associated Secretory Phenotype (SASP) CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling RSK activation Gastrin-CREB signalling pathway via PKC and MAPK +13 more

Autophagy - other Autophagy - animal mTOR signaling pathway PI3K-Akt signaling pathway AMPK signaling pathway Longevity regulating pathway Longevity regulating pathway - multiple species Thermogenesis Insulin signaling pathway Shigellosis MicroRNAs in cancer Macroautophagy mTOR signalling mTORC1-mediated signalling HSF1-dependent transactivation Energy dependent regulation of mTOR by LKB1-AMPK TP53 Regulates Metabolic Genes Regulation of PTEN gene transcription Amino acids regulate mTORC1 +16 more

Post-translational modification: synthesis of GPI-anchored proteins

Pathways in cancer Transcriptional misregulation in cancer Acute myeloid leukemia

PPAR signaling pathway Th17 cell differentiation Thyroid hormone signaling pathway Adipocytokine signaling pathway Parathyroid hormone synthesis, secretion and action Pathways in cancer Transcriptional misregulation in cancer Chemical carcinogenesis - receptor activation Thyroid cancer Small cell lung cancer Non-small cell lung cancer Gastric cancer Lipid and atherosclerosis Nuclear Receptor transcription pathway Signaling by Retinoic Acid +12 more

Calcium signaling pathway cAMP signaling pathway Cardiac muscle contraction Adrenergic signaling in cardiomyocytes Apelin signaling pathway Circadian entrainment Insulin secretion Oxytocin signaling pathway Pancreatic secretion Prion disease Pathways of neurodegeneration - multiple diseases Hypertrophic cardiomyopathy Arrhythmogenic right ventricular cardiomyopathy Dilated cardiomyopathy Diabetic cardiomyopathy Stimuli-sensing channels Ion homeostasis +14 more

Salmonella infection Dissolution of Fibrin Clot

Nuclear signaling by ERBB4 TAK1 activates NFkB by phosphorylation and activation of IKKs complex Advanced glycosylation endproduct receptor signaling TRAF6 mediated NF-kB activation +1 more

FoxO signaling pathway Sphingolipid signaling pathway Neuroactive ligand-receptor interaction Efferocytosis G alpha (i) signalling events Lysosphingolipid and LPA receptors Interleukin-4 and Interleukin-13 signaling +4 more

Arginine and proline metabolism Metabolic pathways Ferroptosis Interconversion of polyamines +1 more

Neutrophil degranulation

Taste transduction Phase 0 - rapid depolarisation

Phase 0 - rapid depolarisation

Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2 +4 more

Protein export Synthesis, secretion, and deacylation of Ghrelin

Protein processing in endoplasmic reticulum Pathogenic Escherichia coli infection COPII-mediated vesicle transport MHC class II antigen presentation Cargo concentration in the ER Antigen Presentation: Folding, assembly and peptide loading of class I MHC +3 more

Axon guidance Sema3A PAK dependent Axon repulsion SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion CRMPs in Sema3A signaling +1 more

Antimicrobial peptides Amyloid fiber formation

SUMO is proteolytically processed

Bacterial invasion of epithelial cells Shigellosis

Complement and coagulation cascades Platelet degranulation COPII-mediated vesicle transport Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Cargo concentration in the ER Neutrophil degranulation Post-translational protein phosphorylation +4 more

MAPK signaling pathway Oocyte meiosis mTOR signaling pathway Thermogenesis Long-term potentiation Neurotrophin signaling pathway Progesterone-mediated oocyte maturation Insulin resistance Yersinia infection Chemical carcinogenesis - receptor activation ERK/MAPK targets CREB phosphorylation Senescence-Associated Secretory Phenotype (SASP) CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling RSK activation Gastrin-CREB signalling pathway via PKC and MAPK +13 more

Synaptic vesicle cycle Retrograde endocannabinoid signaling Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle GABA synthesis, release, reuptake and degradation +5 more

MAPK signaling pathway Oocyte meiosis mTOR signaling pathway Thermogenesis Long-term potentiation Neurotrophin signaling pathway Progesterone-mediated oocyte maturation Insulin resistance Yersinia infection Chemical carcinogenesis - receptor activation ERK/MAPK targets CREB phosphorylation Senescence-Associated Secretory Phenotype (SASP) CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling RSK activation Gastrin-CREB signalling pathway via PKC and MAPK +13 more

Nuclear signaling by ERBB4 TAK1 activates NFkB by phosphorylation and activation of IKKs complex Advanced glycosylation endproduct receptor signaling TRAF6 mediated NF-kB activation +1 more

Taste transduction Phase 0 - rapid depolarisation

Complement and coagulation cascades Platelet degranulation COPII-mediated vesicle transport Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Cargo concentration in the ER Neutrophil degranulation Post-translational protein phosphorylation +4 more

Synaptic vesicle cycle Retrograde endocannabinoid signaling Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle GABA synthesis, release, reuptake and degradation +5 more

MAPK signaling pathway Oocyte meiosis mTOR signaling pathway Thermogenesis Long-term potentiation Neurotrophin signaling pathway Progesterone-mediated oocyte maturation Insulin resistance Yersinia infection Chemical carcinogenesis - receptor activation ERK/MAPK targets CREB phosphorylation Senescence-Associated Secretory Phenotype (SASP) CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling RSK activation Gastrin-CREB signalling pathway via PKC and MAPK +13 more

Nuclear signaling by ERBB4 TAK1 activates NFkB by phosphorylation and activation of IKKs complex Advanced glycosylation endproduct receptor signaling TRAF6 mediated NF-kB activation +1 more

Taste transduction Phase 0 - rapid depolarisation

Complement and coagulation cascades Platelet degranulation COPII-mediated vesicle transport Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Cargo concentration in the ER Neutrophil degranulation Post-translational protein phosphorylation +4 more