Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
acute myeloid leukemia	MONDO_0018874	LSM14A	Unknown	29253671	Open Targets	—
		LYN	Unknown	21606962	Open Targets	Chemokine signaling pathway NF-kappa B signaling pathway Platelet activation +36 more
		LZTR1	Unknown	27798625 38212634 34778799	Open Targets	—
		MAML2	Unknown	25962120 22237025	Open Targets	Notch signaling pathway Th1 and Th2 cell differentiation Human papillomavirus infection +9 more
		MAP2K1	Unknown	29795382 22237025	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +99 more
		MAP3K1	Unknown	31648334	Open Targets	MAPK signaling pathway Ubiquitin mediated proteolysis Tight junction +11 more
		MBD4	Unknown	12417741 35460607 32239153 30049810 29760383 35381620 32421892	Open Targets	Base excision repair Recognition and association of DNA glycosylase with site containing an affected pyrimidine Cleavage of the damaged pyrimidine +1 more
		MDM2	Unknown	25962120	Open Targets	Endocrine resistance Platinum drug resistance FoxO signaling pathway +35 more
		MED12	Unknown	37853686 29795382 30013198 27435003 34778799	Open Targets	Thyroid hormone signaling pathway PPARA activates gene expression Generic Transcription Pathway +1 more
		MET	Unknown	27460089	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +37 more
		MGMT	Unknown	22237025	Open Targets	MGMT-mediated DNA damage reversal
		MITF	Unknown	25962120 24056718	Open Targets	Mitophagy - animal Osteoclast differentiation Melanogenesis +4 more
		MLH1	Unknown	37002311	Open Targets	Platinum drug resistance Mismatch repair Fanconi anemia pathway +8 more
		MLLT1	Unknown	17145626 8639852	Open Targets	Viral life cycle - HIV-1 Transcriptional misregulation in cancer Formation of RNA Pol II elongation complex +2 more
		MLLT10	Unknown	11477655 26131423 23278644 11135434 16213369 22261229 9305618 16111539 17074587 25475940 7564531	Open Targets	—
		MLLT11	Unknown	22854283 10700861 10025907 7833468	Open Targets	—
		MLLT3	Unknown	8630416 20061019 21474990 14506704 25422805 8414510 16450356 15182340 20051780 15188459 16330435	Open Targets	Viral life cycle - HIV-1 Transcriptional misregulation in cancer Formation of RNA Pol II elongation complex +2 more
		MLLT6	Unknown	8058765 16105757	Open Targets	—
		MN1	Unknown	15229617 29273914 11442509 27798625 17476096 26438511 34778799	Open Targets	—
		MPL	Unknown	18755984 37002311 34070172 16868251 29253671 19194467 23153540 27276561 24056718 35805006 34778799	Open Targets	Cytokine-cytokine receptor interaction Hormone signaling JAK-STAT signaling pathway
		MRTFA	Unknown	29253671	Open Targets	SUMOylation of transcription cofactors RHO GTPases Activate Formins
		MSH2	Unknown	37002311	Open Targets	Platinum drug resistance Mismatch repair Pathways in cancer +7 more
		MSH6	Unknown	31648334 22976956 27063598	Open Targets	Platinum drug resistance Mismatch repair Pathways in cancer +4 more
		MSI2	Unknown	22237025 34778799	Open Targets	mRNA surveillance pathway
		MSN	Unknown	29253671	Open Targets	Tight junction Leukocyte transendothelial migration Regulation of actin cytoskeleton +4 more
		MTOR	Unknown	25962120 34778799	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance ErbB signaling pathway +61 more
		MUC16	Unknown	27798625 29795382 22237025 30013198 26438511 34778799	Open Targets	Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC) Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) Defective GALNT12 causes colorectal cancer 1 (CRCS1) +3 more
		MUC4	Unknown	22237025 34778799	Open Targets	Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC) Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) Defective GALNT12 causes colorectal cancer 1 (CRCS1) +3 more
		MUC6	Unknown	27798625	Open Targets	Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC) Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) Defective GALNT12 causes colorectal cancer 1 (CRCS1) +3 more
		MUTYH	Unknown	34778799	Open Targets	Base excision repair Recognition and association of DNA glycosylase with site containing an affected purine Cleavage of the damaged purine +2 more
		MYB	Unknown	29795382	Open Targets	PI3K-Akt signaling pathway RUNX1 regulates transcription of genes involved in differentiation of HSCs Estrogen-dependent gene expression
		MYH11	Unknown	26941285 25962120 30013198	Open Targets	Virion - Lassa virus and SFTS virus Vascular smooth muscle contraction Tight junction +6 more
		NBEA	Unknown	26941285	Open Targets	—
		NBN	Unknown	25962120	Open Targets	Homologous recombination Cellular senescence DNA Damage/Telomere Stress Induced Senescence +13 more
		NCOA2	Unknown	22237025	Open Targets	Estrogen signaling pathway Thyroid hormone signaling pathway RORA activates gene expression +14 more
		NCOR1	Unknown	27798625 25381062 38212634	Open Targets	Endocrine resistance TGF-beta signaling pathway Thyroid hormone signaling pathway +16 more
		NCOR2	Unknown	22976956	Open Targets	Notch signaling pathway Epstein-Barr virus infection PPARA activates gene expression +11 more
		NF2	Unknown	22081132	Open Targets	Hippo signaling pathway Hippo signaling pathway - multiple species Tight junction +2 more
		NFATC2	Unknown	34778799	Open Targets	Calcium signaling pathway cGMP-PKG signaling pathway Efferocytosis +24 more
		NFE2L2	Unknown	22237025 34778799	Open Targets	Protein processing in endoplasmic reticulum Parkinson disease Pathways in cancer +4 more
		NFKB2	Unknown	26883104	Open Targets	MAPK signaling pathway NF-kappa B signaling pathway Osteoclast differentiation +19 more
		NIN	Unknown	29795382	Open Targets	—
		NKX2-1	Unknown	35986270	Open Targets	—
		NOTCH1	Unknown	17008890 17107915 17671232 18281529 22976956 25962120 26438511 27288520 31184605 33711909 34301788 34778799 35805006 37002311 37853686 38212634	Open Targets	Endocrine resistance Notch signaling pathway Th1 and Th2 cell differentiation +20 more
		NOTCH2	Unknown	25564152 26941285 37305720	Open Targets	Endocrine resistance Notch signaling pathway Th1 and Th2 cell differentiation +13 more
		NR2F2	Unknown	34778799	Open Targets	—
		NRG1	Unknown	26941285	Open Targets	EGFR tyrosine kinase inhibitor resistance ErbB signaling pathway Amyotrophic lateral sclerosis +18 more
		NSD2	Unknown	29795382 22237025	Open Targets	Lysine degradation Metabolic pathways Transcriptional misregulation in cancer +5 more
		NT5C2	Unknown	29795382 27288520	Open Targets	Purine metabolism Pyrimidine metabolism Nicotinate and nicotinamide metabolism +4 more
		NTRK2	Unknown	22237025 32315394 34778799	Open Targets	MAPK signaling pathway Ras signaling pathway Calcium signaling pathway +6 more

Acute myeloid leukemia

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