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Gene Gene information from NCBI Gene database.
Entrez ID 55432
Gene name YOD1 deubiquitinase
Gene symbol YOD1
Synonyms (NCBI Gene)
DUBA-8DUBA8HIN-7OTUD2PRO0907
Chromosome 1
Chromosome location 1q32.1
Summary Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional activation, and signal transduction. This dynamic process, involving ubiquitin conjugating enzymes and deubiquitinating enzymes, adds and remov
miRNA miRNA information provided by mirtarbase database.
1304 Show/Hide all (1304)
miRTarBase ID miRNA Experiments Reference
MIRT020095 hsa-miR-361-5p Sequencing 20371350
MIRT021311 hsa-miR-125a-5p Sequencing 20371350
MIRT023456 hsa-miR-30b-5p Sequencing 20371350
MIRT025189 hsa-miR-181a-5p Sequencing 20371350
MIRT027868 hsa-miR-98-5p Microarray 19088304
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
34 Show/Hide all (34)
GO ID Ontology Definition Evidence Reference
GO:0003824 Function Catalytic activity IEA
GO:0004843 Function Cysteine-type deubiquitinase activity IBA
GO:0004843 Function Cysteine-type deubiquitinase activity IDA 19818707, 21376232
GO:0004843 Function Cysteine-type deubiquitinase activity IEA
GO:0005515 Function Protein binding IPI 19818707, 27753622, 32296183
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
612023 25035 ENSG00000180667
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q5VVQ6
Protein name Ubiquitin thioesterase OTU1 (EC 3.4.19.12) (DUBA-8) (HIV-1-induced protease 7) (HIN-7) (HsHIN7) (OTU domain-containing protein 2)
Protein function Hydrolase that can remove conjugated ubiquitin from proteins and participates in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by triming the ubiquitin chain on the associated substrate to facilitate
PDB 4BOQ , 4BOS , 4BOZ
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF02338 OTU 155 → 273 OTU-like cysteine protease Family
Sequence
MFGPAKGRHFGVHPAPGFPGGVSQQAAGTKAGPAGAWPVGSRTDTMWRLRCKAKDGTHVL
QGLSSRTRVRELQGQIAAITGIAPGGQRILVGYPPECLDLSNGDTILEDLPIQSGDMLII
EEDQTRPRSSPAFTKRGASSYVRETLPVLTRTVVPADNSCLFTSVYYVVEGGVLNPACAP
EMRRLIAQIVASDPDFYSEAILGKTNQEYCDWIKRDDTWGGAIEISILSKFYQCEICVVD
TQTVRIDRFGEDAGYTKRVLLIYDGIHYDPLQR
NFPDPDTPPLTIFSSNDDIVLVQALEL
ADEARRRRQFTDVNRFTLRCMVCQKGLTGQAEAREHAKETGHTNFGEV
Sequence length 348
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
KEGG Pathway Reactome Pathway
Protein processing in endoplasmic reticulum Ovarian tumor domain proteases