UBE2J1 (ubiquitin conjugating enzyme E2 J1)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 51465 |
| Gene name | Ubiquitin conjugating enzyme E2 J1 |
| Gene symbol | UBE2J1 |
| Synonyms (NCBI Gene) |
CGI-76HSPC153HSPC205HSU93243NCUBE-1NCUBE1UBC6UBC6EUbc6p
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| Chromosome | 6 |
| Chromosome location | 6q15 |
| Summary | The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conju |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q9Y385 | ||||||||||
| Protein name | Ubiquitin-conjugating enzyme E2 J1 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme J1) (Non-canonical ubiquitin-conjugating enzyme 1) (NCUBE-1) (Yeast ubiquitin-conjugating enzyme UBC6 homolog E) (HsUBC6e) | ||||||||||
| Protein function | Catalyzes the covalent attachment of ubiquitin to other proteins. Functions in the selective degradation of misfolded membrane proteins from the endoplasmic reticulum (ERAD) and is essential for cells to recover from ER stress (PubMed:28321712). | ||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Expressed in testes. {ECO:0000269|PubMed:35831855}. | ||||||||||
| Sequence |
METRYNLKSPAVKRLMKEAAELKDPTDHYHAQPLEDNLFEWHFTVRGPPDSDFDGGVYHG |
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| Sequence length | 318 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Related Genes
Genes most often co-reported with UBE2J1 across shared curated disease and pathway associations.
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Diseases Linked via Similar Genes
Diseases curated for genes most similar to UBE2J1 (see Related Genes above), that are NOT already directly curated for UBE2J1 itself -- a lead worth checking, not a confirmed association.
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