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Gene Gene information from NCBI Gene database.
Entrez ID 51619
Gene name Ubiquitin conjugating enzyme E2 D4
Gene symbol UBE2D4
Synonyms (NCBI Gene)
HBUCE1
Chromosome 7
Chromosome location 7p13
miRNA miRNA information provided by mirtarbase database.
947 Show/Hide all (947)
miRTarBase ID miRNA Experiments Reference
MIRT628970 hsa-miR-299-3p HITS-CLIP 23824327
MIRT628969 hsa-miR-383-3p HITS-CLIP 23824327
MIRT675828 hsa-miR-4284 HITS-CLIP 23824327
MIRT628968 hsa-miR-7106-5p HITS-CLIP 23824327
MIRT628967 hsa-miR-149-3p HITS-CLIP 23824327
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
22 Show/Hide all (22)
GO ID Ontology Definition Evidence Reference
GO:0000166 Function Nucleotide binding IEA
GO:0004842 Function Ubiquitin-protein transferase activity IDA 20061386
GO:0005515 Function Protein binding IPI 15231748, 16189514, 19549727, 19690564, 21516116, 25416956, 28514442, 31515488, 32296183, 32814053, 33961781
GO:0005524 Function ATP binding IEA
GO:0005634 Component Nucleus IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9Y2X8
Protein name Ubiquitin-conjugating enzyme E2 D4 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme D4) (HBUCE1) (Ubiquitin carrier protein D4) (Ubiquitin-protein ligase D4)
Protein function Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro able to promote polyubiquitination using all 7 ubiquitin Lys residues, but may prefer 'Lys-11' and 'Lys-48'-linked polyubiquitination. {ECO:0
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00179 UQ_con 5 → 142 Ubiquitin-conjugating enzyme Domain
Sequence
Sequence length 147
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
KEGG Pathway Reactome Pathway
Polycomb repressive complex Antigen processing: Ubiquitination & Proteasome degradation
Ubiquitin mediated proteolysis  
Protein processing in endoplasmic reticulum  
Shigellosis