Gene Gene information from NCBI Gene database. Download as csv Download as pdf
Entrez ID	78988
Gene name	Mitochondrial ribosomal protein L57
Gene symbol	MRPL57
Synonyms (NCBI Gene)	MRP63bMRP63mL63
Chromosome	13
Chromosome location	13q12.11
Summary	Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% prot

58 Show/Hide all (58)

miRTarBase ID	miRNA	Experiments	Reference
MIRT740859	hsa-miR-106a-5p	HITS-CLIP	23313552
MIRT740860	hsa-miR-106b-5p	HITS-CLIP	23313552
MIRT740861	hsa-miR-17-5p	HITS-CLIP	23313552
MIRT740862	hsa-miR-20a-5p	HITS-CLIP	23313552
MIRT740863	hsa-miR-20b-5p	HITS-CLIP	23313552
MIRT740864	hsa-miR-519d-3p	HITS-CLIP	23313552
MIRT740865	hsa-miR-526b-3p	HITS-CLIP	23313552
MIRT740866	hsa-miR-93-5p	HITS-CLIP	23313552
MIRT740867	hsa-miR-302a-3p	HITS-CLIP	23313552
MIRT740868	hsa-miR-302b-3p	HITS-CLIP	23313552
MIRT740869	hsa-miR-302c-3p	HITS-CLIP	23313552
MIRT740870	hsa-miR-302d-3p	HITS-CLIP	23313552
MIRT740871	hsa-miR-302e	HITS-CLIP	23313552
MIRT740872	hsa-miR-372-3p	HITS-CLIP	23313552
MIRT740873	hsa-miR-373-3p	HITS-CLIP	23313552
MIRT740874	hsa-miR-520a-3p	HITS-CLIP	23313552
MIRT740875	hsa-miR-520b	HITS-CLIP	23313552
MIRT740876	hsa-miR-520c-3p	HITS-CLIP	23313552
MIRT740877	hsa-miR-520d-3p	HITS-CLIP	23313552
MIRT740878	hsa-miR-520e	HITS-CLIP	23313552
MIRT740879	hsa-miR-4438	HITS-CLIP	23313552
MIRT740880	hsa-miR-512-3p	HITS-CLIP	23313552
MIRT740881	hsa-miR-6504-3p	HITS-CLIP	23313552
MIRT740882	hsa-miR-520g-3p	HITS-CLIP	23313552
MIRT740883	hsa-miR-520h	HITS-CLIP	23313552
MIRT740884	hsa-miR-4258	HITS-CLIP	23313552
MIRT740885	hsa-miR-7108-3p	HITS-CLIP	23313552
MIRT740886	hsa-miR-4485-5p	HITS-CLIP	23313552
MIRT740887	hsa-miR-6506-5p	HITS-CLIP	23313552
MIRT740888	hsa-miR-4731-5p	HITS-CLIP	23313552
MIRT740889	hsa-miR-5589-5p	HITS-CLIP	23313552
MIRT740890	hsa-miR-5095	HITS-CLIP	23313552
MIRT740891	hsa-miR-7151-3p	HITS-CLIP	23313552
MIRT740892	hsa-miR-6807-5p	HITS-CLIP	23313552
MIRT740893	hsa-miR-5089-5p	HITS-CLIP	23313552
MIRT742030	hsa-miR-4317	HITS-CLIP	23824327
MIRT742031	hsa-miR-6741-3p	HITS-CLIP	23824327
MIRT742032	hsa-miR-1307-3p	HITS-CLIP	23824327
MIRT742033	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT742034	hsa-miR-3615	HITS-CLIP	23824327
MIRT742035	hsa-miR-2682-3p	HITS-CLIP	23824327
MIRT742036	hsa-miR-6781-3p	HITS-CLIP	23824327
MIRT742037	hsa-miR-4284	HITS-CLIP	23824327
MIRT742038	hsa-miR-5001-3p	HITS-CLIP	23824327
MIRT742297	hsa-miR-7851-3p	HITS-CLIP	23824327
MIRT742298	hsa-miR-6765-3p	HITS-CLIP	23824327
MIRT742299	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT742300	hsa-miR-6742-3p	HITS-CLIP	23824327
MIRT742301	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT742302	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT742303	hsa-miR-23a-5p	HITS-CLIP	23824327
MIRT742304	hsa-miR-23b-5p	HITS-CLIP	23824327
MIRT742297	hsa-miR-7851-3p	HITS-CLIP	23824327
MIRT742298	hsa-miR-6765-3p	HITS-CLIP	23824327
MIRT742300	hsa-miR-6742-3p	HITS-CLIP	23824327
MIRT742302	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT742303	hsa-miR-23a-5p	HITS-CLIP	23824327
MIRT742304	hsa-miR-23b-5p	HITS-CLIP	23824327

19 Show/Hide all (19)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003735	Function	Structural constituent of ribosome	IBA
GO:0003735	Function	Structural constituent of ribosome	IEA
GO:0003735	Function	Structural constituent of ribosome	ISS	11402041
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005739	Component	Mitochondrion	HTP	34800366
GO:0005739	Component	Mitochondrion	IDA	28892042
GO:0005739	Component	Mitochondrion	IEA
GO:0005743	Component	Mitochondrial inner membrane	NAS	27023846
GO:0005743	Component	Mitochondrial inner membrane	TAS
GO:0005761	Component	Mitochondrial ribosome	IBA
GO:0005761	Component	Mitochondrial ribosome	IEA
GO:0005761	Component	Mitochondrial ribosome	ISS	11402041
GO:0005762	Component	Mitochondrial large ribosomal subunit	IDA	28892042
GO:0005762	Component	Mitochondrial large ribosomal subunit	NAS	25278503
GO:0005840	Component	Ribosome	IEA
GO:0006412	Process	Translation	IEA
GO:0032543	Process	Mitochondrial translation	ISS	11402041
GO:0032543	Process	Mitochondrial translation	NAS	27023846
GO:1990904	Component	Ribonucleoprotein complex	IEA

MIM	HGNC	e!Ensembl
611997	14514	ENSG00000173141

Q9BQC6

Protein name

Large ribosomal subunit protein mL63 (Mitochondrial ribosomal protein 63) (Mitochondrial ribosomal protein L57) (Ribosomal protein 63, mitochondrial) (hMRP63)

PDB

3J7Y , 3J9M , 5OOL , 5OOM , 6I9R , 6NU2 , 6NU3 , 6VLZ , 6VMI , 6ZM5 , 6ZM6 , 6ZS9 , 6ZSA , 6ZSB , 6ZSC , 6ZSD , 6ZSE , 6ZSG , 7A5F , 7A5G , 7A5H , 7A5I , 7A5J , 7A5K , 7L08 , 7L20 , 7O9K , 7O9M , 7ODR , 7ODS , 7ODT , 7OF0 , 7OF2 , 7OF3 , 7OF4 , 7OF5 , 7OF6 , 7OF7 , 7OG4 , 7OI6 , 7OI7 , 7OI8 , 7OI9 , 7OIA , 7OIB , 7OIC , 7OID , 7OIE , 7PD3 , 7PO4 , 7QH6

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF14978	MRP-63	13 → 101	Mitochondrial ribosome protein 63	Family

Sequence

MFLTALLWRGRIPGRQWIGKHRRPRFVSLRAKQNMIRRLEIEAENHYWLSMPYMTREQER
GHAAVRRREAFEAIKAAATSKFPPHRFIADQLDHLNVTKKWS

Sequence length

102

Interactions

View interactions

Reactome Pathway
Mitochondrial translation elongation
Mitochondrial translation termination

MRPL57 (mitochondrial ribosomal protein L57)

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