Gene Gene information from NCBI Gene database. Download as csv Download as pdf
Entrez ID	116541
Gene name	Mitochondrial ribosomal protein L54
Gene symbol	MRPL54
Synonyms (NCBI Gene)	L54mtMRP-L54mL54
Chromosome	19
Chromosome location	19p13.3
Summary	Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% prot

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miRTarBase ID	miRNA	Experiments	Reference
MIRT039931	hsa-miR-615-3p	CLASH	23622248
MIRT1159585	hsa-miR-1291	CLIP-seq
MIRT1159586	hsa-miR-3150a-3p	CLIP-seq
MIRT1159587	hsa-miR-3151	CLIP-seq
MIRT1159588	hsa-miR-3175	CLIP-seq
MIRT1159589	hsa-miR-3688-3p	CLIP-seq
MIRT1159590	hsa-miR-3918	CLIP-seq
MIRT1159591	hsa-miR-4261	CLIP-seq
MIRT1159592	hsa-miR-4286	CLIP-seq
MIRT1159593	hsa-miR-4318	CLIP-seq
MIRT1159594	hsa-miR-4323	CLIP-seq
MIRT1159595	hsa-miR-4447	CLIP-seq
MIRT1159596	hsa-miR-4472	CLIP-seq
MIRT1159597	hsa-miR-4505	CLIP-seq
MIRT1159598	hsa-miR-4667-5p	CLIP-seq
MIRT1159599	hsa-miR-4685-5p	CLIP-seq
MIRT1159600	hsa-miR-4700-5p	CLIP-seq
MIRT1159601	hsa-miR-4717-3p	CLIP-seq
MIRT1159602	hsa-miR-4731-5p	CLIP-seq
MIRT1159603	hsa-miR-4758-3p	CLIP-seq
MIRT1159604	hsa-miR-4802-3p	CLIP-seq
MIRT1159605	hsa-miR-491-5p	CLIP-seq
MIRT1159606	hsa-miR-615-5p	CLIP-seq
MIRT1159607	hsa-miR-939	CLIP-seq
MIRT1159590	hsa-miR-3918	CLIP-seq
MIRT1159599	hsa-miR-4685-5p	CLIP-seq
MIRT2045824	hsa-miR-4757-5p	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0003723	Function	RNA binding	HDA	22681889
GO:0003735	Function	Structural constituent of ribosome	IBA
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005739	Component	Mitochondrion	HTP	34800366
GO:0005739	Component	Mitochondrion	IDA	28892042
GO:0005739	Component	Mitochondrion	IEA
GO:0005743	Component	Mitochondrial inner membrane	NAS	27023846
GO:0005743	Component	Mitochondrial inner membrane	TAS
GO:0005762	Component	Mitochondrial large ribosomal subunit	IBA
GO:0005762	Component	Mitochondrial large ribosomal subunit	IDA	25838379, 28892042
GO:0005762	Component	Mitochondrial large ribosomal subunit	NAS	25278503
GO:0005840	Component	Ribosome	IEA
GO:0032543	Process	Mitochondrial translation	NAS	27023846
GO:1990904	Component	Ribonucleoprotein complex	IEA

MIM	HGNC	e!Ensembl
611858	16685	ENSG00000183617

Q6P161

Protein name

Large ribosomal subunit protein mL54 (39S ribosomal protein L54, mitochondrial) (L54mt) (MRP-L54)

PDB

3J9M , 5OOL , 5OOM , 6I9R , 6NU2 , 6NU3 , 6VLZ , 6VMI , 6ZM5 , 6ZM6 , 6ZS9 , 6ZSA , 6ZSB , 6ZSC , 6ZSD , 6ZSE , 6ZSG , 7A5F , 7A5G , 7A5H , 7A5I , 7A5J , 7A5K , 7L08 , 7L20 , 7O9K , 7O9M , 7ODR , 7ODS , 7ODT , 7OF2 , 7OF4 , 7OF6 , 7OG4 , 7OI6 , 7OI7 , 7OI8 , 7OI9 , 7OIA , 7OIB , 7OIC , 7OID , 7OIE , 7PD3 , 7PO4 , 7QI4 , 7QI5 , 7QI6 , 8ANY , 8K2A , 8K2B

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF08561	Ribosomal_L37	62 → 124	Mitochondrial ribosomal protein L37	Family

Sequence

MATKRLFGATRTWAGWGAWELLNPATSGRLLARDYAKKPVMKGAKSGKGAVTSEALKDPD
VCTDPVQLTTYAMGVNIYKEGQDVPLKPDAEYPEWLFEMNLGPPKTLEELDPESREYWRR
LRKQNIWRHNRLSKNKRL

Sequence length

138

Interactions

View interactions

Reactome Pathway
Mitochondrial translation elongation
Mitochondrial translation termination

MRPL54 (mitochondrial ribosomal protein L54)

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