MRPL41 (mitochondrial ribosomal protein L41)

Download as csv Download as pdf
Log in to bookmark this gene

Bookmark This Gene

Gene Gene information from NCBI Gene database.
Download as csvDownload as pdf
Entrez ID 64975
Gene name Mitochondrial ribosomal protein L41
Gene symbol MRPL41
Synonyms (NCBI Gene)
BMRPMRP-L27MRPL27PIG3RPML27mL41
Chromosome 9
Chromosome location 9q34.3
Summary Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% prot
miRNA miRNA information provided by mirtarbase database.
19 Show/Hide all (19)
Download as csvDownload as pdf
miRTarBase ID miRNA Experiments Reference
MIRT716315 hsa-miR-34a-3p HITS-CLIP 19536157
MIRT716314 hsa-miR-3617-3p HITS-CLIP 19536157
MIRT716313 hsa-miR-3065-3p HITS-CLIP 19536157
MIRT716312 hsa-miR-383-3p HITS-CLIP 19536157
MIRT716311 hsa-miR-3622b-5p HITS-CLIP 19536157
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
21 Show/Hide all (21)
Download as csvDownload as pdf
GO ID Ontology Definition Evidence Reference
GO:0003723 Function RNA binding HDA 22658674, 22681889
GO:0003735 Function Structural constituent of ribosome IBA
GO:0003735 Function Structural constituent of ribosome IDA 16024796
GO:0003735 Function Structural constituent of ribosome IEA
GO:0005515 Function Protein binding IPI 18157088, 32296183
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
Download as csvDownload as pdf
MIM HGNC e!Ensembl
611846 14492 ENSG00000182154
Protein Protein information from UniProt database.
Download as csvDownload as pdf
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q8IXM3
Protein name Large ribosomal subunit protein mL41 (39S ribosomal protein L41, mitochondrial) (L41mt) (MRP-L41) (Bcl-2-interacting mitochondrial ribosomal protein L41) (Cell proliferation-inducing gene 3 protein) (MRP-L27 homolog)
Protein function Component of the mitochondrial ribosome large subunit (PubMed:25278503, PubMed:25838379, PubMed:28892042, PubMed:35177605). Also involved in apoptosis and cell cycle (PubMed:16024796, PubMed:16256947). Enhances p53/TP53 stability, thereby contri
PDB 3J7Y , 3J9M , 5OOL , 5OOM , 6I9R , 6NU2 , 6NU3 , 6VLZ , 6VMI , 6ZM5 , 6ZM6 , 6ZS9 , 6ZSA , 6ZSB , 6ZSC , 6ZSD , 6ZSE , 6ZSG , 7A5F , 7A5G , 7A5H , 7A5I , 7A5J , 7A5K , 7L08 , 7L20 , 7O9K , 7O9M , 7ODR , 7ODS , 7ODT , 7OF0 , 7OF2 , 7OF3 , 7OF4 , 7OF5 , 7OF6 , 7OF7 , 7OG4 , 7OI6 , 7OI7 , 7OI8 , 7OI9 , 7OIA , 7OIB , 7OIC , 7OID , 7OIE , 7PD3 , 7PO4 , 7QH6
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF09809 MRP-L27 13 → 127 Mitochondrial ribosomal protein L27 Family
Tissue specificity TISSUE SPECIFICITY: Present in kidney, liver, thymus and testis, and at lower level in brain and spleen (at protein level). {ECO:0000269|PubMed:15547950}.
Sequence 
MGVLAAAARCLVRGADRMSKWTSKRGPRSFRGRKGRGAKGIGFLTSGWRFVQIKEMVPEF
VVPDLTGFKLKPYVSYLAPESEETPLTAAQLFSEAVAPAIEKDFKDGTFDPDNLEKYGFE
PTQEGKLFQLYPRNFLR
Sequence length 137
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Download as csvDownload as pdf
Reactome Pathway
Mitochondrial translation elongation
Mitochondrial translation termination
Sort by:
MRPS31 2 shared pathwaysMitochondrial translation elongation, Mitochondrial translation termination Related via 2 shared pathways including Mitochondrial translation elongation, Mitochondrial translation termination. MRPS30 2 shared pathwaysMitochondrial translation elongation, Mitochondrial translation termination Related via 2 shared pathways including Mitochondrial translation elongation, Mitochondrial translation termination. MRPL53 2 shared pathwaysMitochondrial translation elongation, Mitochondrial translation termination Related via 2 shared pathways including Mitochondrial translation elongation, Mitochondrial translation termination. MRPL54 2 shared pathwaysMitochondrial translation elongation, Mitochondrial translation termination Related via 2 shared pathways including Mitochondrial translation elongation, Mitochondrial translation termination. CHCHD1 2 shared pathwaysMitochondrial translation elongation, Mitochondrial translation termination Related via 2 shared pathways including Mitochondrial translation elongation, Mitochondrial translation termination.
Myeloproliferative disorder Linked via 1 of 5 related genesMRPS31 Alzheimer disease Linked via 1 of 5 related genesMRPS30 Anorexia nervosa Linked via 1 of 5 related genesMRPS30 Attention deficit hyperactivity disorder Linked via 1 of 5 related genesMRPS30 Breast cancer Linked via 1 of 5 related genesMRPS30