MGAT5B (alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B)

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Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases Related genes Diseases linked via similar genes

Gene

• Entrez ID: 146664
• Gene name: Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B
• Gene symbol: MGAT5B
• Synonyms (NCBI Gene): GnT-IX, GnT-VB
• Chromosome: 17
• Chromosome location: 17q25.2
• Summary: The MGAT5B gene encodes a beta-1,6-N-acetylglucosaminyltransferase (EC 2.4.1.155) that functions in the synthesis of complex cell surface N-glycans (Kaneko et al., 2003 [PubMed 14623122]).[supplied by OMIM, Nov 2008]

miRNA Show/Hide all (262)

miRTarBase ID	miRNA	Experiments	Reference
MIRT716472	hsa-miR-6849-3p	HITS-CLIP	19536157
MIRT709057	hsa-miR-6887-3p	HITS-CLIP	19536157
MIRT709054	hsa-miR-4749-3p	HITS-CLIP	19536157
MIRT709053	hsa-miR-874-5p	HITS-CLIP	19536157
MIRT716471	hsa-miR-6512-3p	HITS-CLIP	19536157
MIRT716470	hsa-miR-6720-5p	HITS-CLIP	19536157
MIRT709059	hsa-miR-4310	HITS-CLIP	19536157
MIRT709058	hsa-miR-7157-5p	HITS-CLIP	19536157
MIRT709057	hsa-miR-6887-3p	HITS-CLIP	19536157
MIRT709056	hsa-miR-6787-3p	HITS-CLIP	19536157
MIRT709055	hsa-miR-324-5p	HITS-CLIP	19536157
MIRT709054	hsa-miR-4749-3p	HITS-CLIP	19536157
MIRT709059	hsa-miR-4310	HITS-CLIP	19536157
MIRT709058	hsa-miR-7157-5p	HITS-CLIP	19536157
MIRT709057	hsa-miR-6887-3p	HITS-CLIP	19536157
MIRT709056	hsa-miR-6787-3p	HITS-CLIP	19536157
MIRT709055	hsa-miR-324-5p	HITS-CLIP	19536157
MIRT709054	hsa-miR-4749-3p	HITS-CLIP	19536157
MIRT709053	hsa-miR-874-5p	HITS-CLIP	19536157
MIRT486734	hsa-miR-5584-5p	PAR-CLIP	20371350
MIRT486733	hsa-miR-6805-5p	PAR-CLIP	20371350
MIRT568880	hsa-miR-4793-5p	PAR-CLIP	20371350
MIRT486732	hsa-miR-5681a	PAR-CLIP	20371350
MIRT486731	hsa-miR-1249-5p	PAR-CLIP	20371350
MIRT486730	hsa-miR-6797-5p	PAR-CLIP	20371350
MIRT486729	hsa-miR-3622b-5p	PAR-CLIP	20371350
MIRT486728	hsa-miR-3153	PAR-CLIP	20371350
MIRT486727	hsa-miR-6733-5p	PAR-CLIP	20371350
MIRT486726	hsa-miR-6739-5p	PAR-CLIP	20371350
MIRT486725	hsa-miR-149-3p	PAR-CLIP	20371350
MIRT486723	hsa-miR-4728-5p	PAR-CLIP	20371350
MIRT486724	hsa-miR-6785-5p	PAR-CLIP	20371350
MIRT486722	hsa-miR-6883-5p	PAR-CLIP	20371350
MIRT486721	hsa-miR-4253	PAR-CLIP	20371350
MIRT486720	hsa-miR-6862-5p	PAR-CLIP	20371350
MIRT486719	hsa-miR-6825-5p	PAR-CLIP	20371350
MIRT486718	hsa-miR-4723-5p	PAR-CLIP	20371350
MIRT486717	hsa-miR-5698	PAR-CLIP	20371350
MIRT486716	hsa-miR-6870-5p	PAR-CLIP	20371350
MIRT486715	hsa-miR-7111-5p	PAR-CLIP	20371350
MIRT486713	hsa-miR-6795-5p	PAR-CLIP	20371350
MIRT486714	hsa-miR-6887-5p	PAR-CLIP	20371350
MIRT486712	hsa-miR-328-5p	PAR-CLIP	20371350
MIRT486711	hsa-miR-6885-5p	PAR-CLIP	20371350
MIRT486710	hsa-miR-7109-5p	PAR-CLIP	20371350
MIRT486709	hsa-miR-6775-5p	PAR-CLIP	20371350
MIRT486734	hsa-miR-5584-5p	PAR-CLIP	20371350
MIRT486733	hsa-miR-6805-5p	PAR-CLIP	20371350
MIRT486732	hsa-miR-5681a	PAR-CLIP	20371350
MIRT486731	hsa-miR-1249-5p	PAR-CLIP	20371350
MIRT486730	hsa-miR-6797-5p	PAR-CLIP	20371350
MIRT486729	hsa-miR-3622b-5p	PAR-CLIP	20371350
MIRT486728	hsa-miR-3153	PAR-CLIP	20371350
MIRT486727	hsa-miR-6733-5p	PAR-CLIP	20371350
MIRT486726	hsa-miR-6739-5p	PAR-CLIP	20371350
MIRT486725	hsa-miR-149-3p	PAR-CLIP	20371350
MIRT486723	hsa-miR-4728-5p	PAR-CLIP	20371350
MIRT486724	hsa-miR-6785-5p	PAR-CLIP	20371350
MIRT486722	hsa-miR-6883-5p	PAR-CLIP	20371350
MIRT486719	hsa-miR-6825-5p	PAR-CLIP	20371350
MIRT486718	hsa-miR-4723-5p	PAR-CLIP	20371350
MIRT486717	hsa-miR-5698	PAR-CLIP	20371350
MIRT486716	hsa-miR-6870-5p	PAR-CLIP	20371350
MIRT486715	hsa-miR-7111-5p	PAR-CLIP	20371350
MIRT486713	hsa-miR-6795-5p	PAR-CLIP	20371350
MIRT486714	hsa-miR-6887-5p	PAR-CLIP	20371350
MIRT486712	hsa-miR-328-5p	PAR-CLIP	20371350
MIRT486711	hsa-miR-6885-5p	PAR-CLIP	20371350
MIRT486710	hsa-miR-7109-5p	PAR-CLIP	20371350
MIRT486709	hsa-miR-6775-5p	PAR-CLIP	20371350
MIRT486734	hsa-miR-5584-5p	PAR-CLIP	20371350
MIRT486733	hsa-miR-6805-5p	PAR-CLIP	20371350
MIRT568880	hsa-miR-4793-5p	PAR-CLIP	20371350
MIRT486732	hsa-miR-5681a	PAR-CLIP	20371350
MIRT486731	hsa-miR-1249-5p	PAR-CLIP	20371350
MIRT486730	hsa-miR-6797-5p	PAR-CLIP	20371350
MIRT486729	hsa-miR-3622b-5p	PAR-CLIP	20371350
MIRT486728	hsa-miR-3153	PAR-CLIP	20371350
MIRT486727	hsa-miR-6733-5p	PAR-CLIP	20371350
MIRT486726	hsa-miR-6739-5p	PAR-CLIP	20371350
MIRT486725	hsa-miR-149-3p	PAR-CLIP	20371350
MIRT486723	hsa-miR-4728-5p	PAR-CLIP	20371350
MIRT486724	hsa-miR-6785-5p	PAR-CLIP	20371350
MIRT486722	hsa-miR-6883-5p	PAR-CLIP	20371350
MIRT486721	hsa-miR-4253	PAR-CLIP	20371350
MIRT486720	hsa-miR-6862-5p	PAR-CLIP	20371350
MIRT486719	hsa-miR-6825-5p	PAR-CLIP	20371350
MIRT486718	hsa-miR-4723-5p	PAR-CLIP	20371350
MIRT486717	hsa-miR-5698	PAR-CLIP	20371350
MIRT486716	hsa-miR-6870-5p	PAR-CLIP	20371350
MIRT486715	hsa-miR-7111-5p	PAR-CLIP	20371350
MIRT486713	hsa-miR-6795-5p	PAR-CLIP	20371350
MIRT486714	hsa-miR-6887-5p	PAR-CLIP	20371350
MIRT486712	hsa-miR-328-5p	PAR-CLIP	20371350
MIRT486711	hsa-miR-6885-5p	PAR-CLIP	20371350
MIRT486710	hsa-miR-7109-5p	PAR-CLIP	20371350
MIRT486709	hsa-miR-6775-5p	PAR-CLIP	20371350
MIRT486734	hsa-miR-5584-5p	PAR-CLIP	23592263
MIRT486733	hsa-miR-6805-5p	PAR-CLIP	23592263
MIRT486732	hsa-miR-5681a	PAR-CLIP	23592263
MIRT486731	hsa-miR-1249-5p	PAR-CLIP	23592263
MIRT486730	hsa-miR-6797-5p	PAR-CLIP	23592263
MIRT486729	hsa-miR-3622b-5p	PAR-CLIP	23592263
MIRT486728	hsa-miR-3153	PAR-CLIP	23592263
MIRT486727	hsa-miR-6733-5p	PAR-CLIP	23592263
MIRT486726	hsa-miR-6739-5p	PAR-CLIP	23592263
MIRT486725	hsa-miR-149-3p	PAR-CLIP	23592263
MIRT486723	hsa-miR-4728-5p	PAR-CLIP	23592263
MIRT486724	hsa-miR-6785-5p	PAR-CLIP	23592263
MIRT486722	hsa-miR-6883-5p	PAR-CLIP	23592263
MIRT486721	hsa-miR-4253	PAR-CLIP	23592263
MIRT486720	hsa-miR-6862-5p	PAR-CLIP	23592263
MIRT486719	hsa-miR-6825-5p	PAR-CLIP	23592263
MIRT486718	hsa-miR-4723-5p	PAR-CLIP	23592263
MIRT486717	hsa-miR-5698	PAR-CLIP	23592263
MIRT486716	hsa-miR-6870-5p	PAR-CLIP	23592263
MIRT486715	hsa-miR-7111-5p	PAR-CLIP	23592263
MIRT486713	hsa-miR-6795-5p	PAR-CLIP	23592263
MIRT486714	hsa-miR-6887-5p	PAR-CLIP	23592263
MIRT486712	hsa-miR-328-5p	PAR-CLIP	23592263
MIRT486711	hsa-miR-6885-5p	PAR-CLIP	23592263
MIRT486710	hsa-miR-7109-5p	PAR-CLIP	23592263
MIRT486709	hsa-miR-6775-5p	PAR-CLIP	23592263
MIRT716472	hsa-miR-6849-3p	HITS-CLIP	19536157
MIRT709057	hsa-miR-6887-3p	HITS-CLIP	19536157
MIRT709054	hsa-miR-4749-3p	HITS-CLIP	19536157
MIRT709053	hsa-miR-874-5p	HITS-CLIP	19536157
MIRT716471	hsa-miR-6512-3p	HITS-CLIP	19536157
MIRT716470	hsa-miR-6720-5p	HITS-CLIP	19536157
MIRT709059	hsa-miR-4310	HITS-CLIP	19536157
MIRT709058	hsa-miR-7157-5p	HITS-CLIP	19536157
MIRT709057	hsa-miR-6887-3p	HITS-CLIP	19536157
MIRT709056	hsa-miR-6787-3p	HITS-CLIP	19536157
MIRT709055	hsa-miR-324-5p	HITS-CLIP	19536157
MIRT709054	hsa-miR-4749-3p	HITS-CLIP	19536157
MIRT709059	hsa-miR-4310	HITS-CLIP	19536157
MIRT709058	hsa-miR-7157-5p	HITS-CLIP	19536157
MIRT709057	hsa-miR-6887-3p	HITS-CLIP	19536157
MIRT709056	hsa-miR-6787-3p	HITS-CLIP	19536157
MIRT709055	hsa-miR-324-5p	HITS-CLIP	19536157
MIRT709054	hsa-miR-4749-3p	HITS-CLIP	19536157
MIRT709053	hsa-miR-874-5p	HITS-CLIP	19536157
MIRT486734	hsa-miR-5584-5p	PAR-CLIP	20371350
MIRT486733	hsa-miR-6805-5p	PAR-CLIP	20371350
MIRT568880	hsa-miR-4793-5p	PAR-CLIP	20371350
MIRT486732	hsa-miR-5681a	PAR-CLIP	20371350
MIRT486731	hsa-miR-1249-5p	PAR-CLIP	20371350
MIRT486730	hsa-miR-6797-5p	PAR-CLIP	20371350
MIRT486729	hsa-miR-3622b-5p	PAR-CLIP	20371350
MIRT486728	hsa-miR-3153	PAR-CLIP	20371350
MIRT486727	hsa-miR-6733-5p	PAR-CLIP	20371350
MIRT486726	hsa-miR-6739-5p	PAR-CLIP	20371350
MIRT486725	hsa-miR-149-3p	PAR-CLIP	20371350
MIRT486723	hsa-miR-4728-5p	PAR-CLIP	20371350
MIRT486724	hsa-miR-6785-5p	PAR-CLIP	20371350
MIRT486722	hsa-miR-6883-5p	PAR-CLIP	20371350
MIRT486721	hsa-miR-4253	PAR-CLIP	20371350
MIRT486720	hsa-miR-6862-5p	PAR-CLIP	20371350
MIRT486719	hsa-miR-6825-5p	PAR-CLIP	20371350
MIRT486718	hsa-miR-4723-5p	PAR-CLIP	20371350
MIRT486717	hsa-miR-5698	PAR-CLIP	20371350
MIRT486716	hsa-miR-6870-5p	PAR-CLIP	20371350
MIRT486715	hsa-miR-7111-5p	PAR-CLIP	20371350
MIRT486713	hsa-miR-6795-5p	PAR-CLIP	20371350
MIRT486714	hsa-miR-6887-5p	PAR-CLIP	20371350
MIRT486712	hsa-miR-328-5p	PAR-CLIP	20371350
MIRT486711	hsa-miR-6885-5p	PAR-CLIP	20371350
MIRT486710	hsa-miR-7109-5p	PAR-CLIP	20371350
MIRT486709	hsa-miR-6775-5p	PAR-CLIP	20371350
MIRT486734	hsa-miR-5584-5p	PAR-CLIP	20371350
MIRT486733	hsa-miR-6805-5p	PAR-CLIP	20371350
MIRT486732	hsa-miR-5681a	PAR-CLIP	20371350
MIRT486731	hsa-miR-1249-5p	PAR-CLIP	20371350
MIRT486730	hsa-miR-6797-5p	PAR-CLIP	20371350
MIRT486729	hsa-miR-3622b-5p	PAR-CLIP	20371350
MIRT486728	hsa-miR-3153	PAR-CLIP	20371350
MIRT486727	hsa-miR-6733-5p	PAR-CLIP	20371350
MIRT486726	hsa-miR-6739-5p	PAR-CLIP	20371350
MIRT486725	hsa-miR-149-3p	PAR-CLIP	20371350
MIRT486723	hsa-miR-4728-5p	PAR-CLIP	20371350
MIRT486724	hsa-miR-6785-5p	PAR-CLIP	20371350
MIRT486722	hsa-miR-6883-5p	PAR-CLIP	20371350
MIRT486719	hsa-miR-6825-5p	PAR-CLIP	20371350
MIRT486718	hsa-miR-4723-5p	PAR-CLIP	20371350
MIRT486717	hsa-miR-5698	PAR-CLIP	20371350
MIRT486716	hsa-miR-6870-5p	PAR-CLIP	20371350
MIRT486715	hsa-miR-7111-5p	PAR-CLIP	20371350
MIRT486713	hsa-miR-6795-5p	PAR-CLIP	20371350
MIRT486714	hsa-miR-6887-5p	PAR-CLIP	20371350
MIRT486712	hsa-miR-328-5p	PAR-CLIP	20371350
MIRT486711	hsa-miR-6885-5p	PAR-CLIP	20371350
MIRT486710	hsa-miR-7109-5p	PAR-CLIP	20371350
MIRT486709	hsa-miR-6775-5p	PAR-CLIP	20371350
MIRT486734	hsa-miR-5584-5p	PAR-CLIP	20371350
MIRT486733	hsa-miR-6805-5p	PAR-CLIP	20371350
MIRT568880	hsa-miR-4793-5p	PAR-CLIP	20371350
MIRT486732	hsa-miR-5681a	PAR-CLIP	20371350
MIRT486731	hsa-miR-1249-5p	PAR-CLIP	20371350
MIRT486730	hsa-miR-6797-5p	PAR-CLIP	20371350
MIRT486729	hsa-miR-3622b-5p	PAR-CLIP	20371350
MIRT486728	hsa-miR-3153	PAR-CLIP	20371350
MIRT486727	hsa-miR-6733-5p	PAR-CLIP	20371350
MIRT486726	hsa-miR-6739-5p	PAR-CLIP	20371350
MIRT486725	hsa-miR-149-3p	PAR-CLIP	20371350
MIRT486723	hsa-miR-4728-5p	PAR-CLIP	20371350
MIRT486724	hsa-miR-6785-5p	PAR-CLIP	20371350
MIRT486722	hsa-miR-6883-5p	PAR-CLIP	20371350
MIRT486721	hsa-miR-4253	PAR-CLIP	20371350
MIRT486720	hsa-miR-6862-5p	PAR-CLIP	20371350
MIRT486719	hsa-miR-6825-5p	PAR-CLIP	20371350
MIRT486718	hsa-miR-4723-5p	PAR-CLIP	20371350
MIRT486717	hsa-miR-5698	PAR-CLIP	20371350
MIRT486716	hsa-miR-6870-5p	PAR-CLIP	20371350
MIRT486715	hsa-miR-7111-5p	PAR-CLIP	20371350
MIRT486713	hsa-miR-6795-5p	PAR-CLIP	20371350
MIRT486714	hsa-miR-6887-5p	PAR-CLIP	20371350
MIRT486712	hsa-miR-328-5p	PAR-CLIP	20371350
MIRT486711	hsa-miR-6885-5p	PAR-CLIP	20371350
MIRT486710	hsa-miR-7109-5p	PAR-CLIP	20371350
MIRT486709	hsa-miR-6775-5p	PAR-CLIP	20371350
MIRT486734	hsa-miR-5584-5p	PAR-CLIP	23592263
MIRT486733	hsa-miR-6805-5p	PAR-CLIP	23592263
MIRT486732	hsa-miR-5681a	PAR-CLIP	23592263
MIRT486731	hsa-miR-1249-5p	PAR-CLIP	23592263
MIRT486730	hsa-miR-6797-5p	PAR-CLIP	23592263
MIRT486729	hsa-miR-3622b-5p	PAR-CLIP	23592263
MIRT486728	hsa-miR-3153	PAR-CLIP	23592263
MIRT486727	hsa-miR-6733-5p	PAR-CLIP	23592263
MIRT486726	hsa-miR-6739-5p	PAR-CLIP	23592263
MIRT486725	hsa-miR-149-3p	PAR-CLIP	23592263
MIRT486723	hsa-miR-4728-5p	PAR-CLIP	23592263
MIRT486724	hsa-miR-6785-5p	PAR-CLIP	23592263
MIRT486722	hsa-miR-6883-5p	PAR-CLIP	23592263
MIRT486721	hsa-miR-4253	PAR-CLIP	23592263
MIRT486720	hsa-miR-6862-5p	PAR-CLIP	23592263
MIRT486719	hsa-miR-6825-5p	PAR-CLIP	23592263
MIRT486718	hsa-miR-4723-5p	PAR-CLIP	23592263
MIRT486717	hsa-miR-5698	PAR-CLIP	23592263
MIRT486716	hsa-miR-6870-5p	PAR-CLIP	23592263
MIRT486715	hsa-miR-7111-5p	PAR-CLIP	23592263
MIRT486713	hsa-miR-6795-5p	PAR-CLIP	23592263
MIRT486714	hsa-miR-6887-5p	PAR-CLIP	23592263
MIRT486712	hsa-miR-328-5p	PAR-CLIP	23592263
MIRT486711	hsa-miR-6885-5p	PAR-CLIP	23592263
MIRT486710	hsa-miR-7109-5p	PAR-CLIP	23592263
MIRT486709	hsa-miR-6775-5p	PAR-CLIP	23592263
MIRT1147335	hsa-miR-185	CLIP-seq
MIRT1147336	hsa-miR-3065-3p	CLIP-seq
MIRT1147337	hsa-miR-4306	CLIP-seq
MIRT1147338	hsa-miR-4644	CLIP-seq
MIRT1147339	hsa-miR-4722-5p	CLIP-seq
MIRT1147340	hsa-miR-4768-3p	CLIP-seq
MIRT1147341	hsa-miR-4795-5p	CLIP-seq
MIRT1147336	hsa-miR-3065-3p	CLIP-seq
MIRT1147342	hsa-miR-3122	CLIP-seq
MIRT1147343	hsa-miR-3689a-3p	CLIP-seq
MIRT1147344	hsa-miR-3689c	CLIP-seq
MIRT1147345	hsa-miR-3913-5p	CLIP-seq
MIRT1147346	hsa-miR-4434	CLIP-seq
MIRT1147347	hsa-miR-4516	CLIP-seq
MIRT1147341	hsa-miR-4795-5p	CLIP-seq
MIRT1147348	hsa-miR-629	CLIP-seq

Gene ontology (GO) Show/Hide all (15)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000139	Component	Golgi membrane	IEA
GO:0005515	Function	Protein binding	IPI	23088713
GO:0005794	Component	Golgi apparatus	IBA
GO:0005794	Component	Golgi apparatus	IEA
GO:0006486	Process	Protein glycosylation	IEA
GO:0006487	Process	Protein N-linked glycosylation	IBA
GO:0006487	Process	Protein N-linked glycosylation	IEA
GO:0016020	Component	Membrane	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0016757	Function	Glycosyltransferase activity	IEA
GO:0030144	Function	Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity	IBA
GO:0030144	Function	Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity	IDA	19846580
GO:0030144	Function	Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity	IEA
GO:0030145	Function	Manganese ion binding	IDA	19846580
GO:0046872	Function	Metal ion binding	IEA

Other IDs

• MIM: 612441
• HGNC: 24140
• e!Ensembl: ENSG00000167889

Protein

• UniProt ID: Q3V5L5
• Protein name: Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B (EC 2.4.1.-) (EC 2.4.1.155) (Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase B) (GlcNAc-T Vb) (GNT-Vb) (hGnTVb) (Mannoside acetylglucosaminyltransferase 5B) (N-acetylglucosam
• Protein function: Glycosyltransferase that acts on alpha-linked mannose of N-glycans and O-mannosyl glycans. Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to the beta 1-6 linkage of the mannose residue of GlcNAc-beta1,2-Man-alpha on both the alpha1,3- an
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF15024	Glyco_transf_18	184 → 777	Glycosyltransferase family 18	Family

• Tissue specificity: TISSUE SPECIFICITY: Predominantly expressed in brain. Expressed in all areas of the adult and fetal brain. Also expressed at much lower levels in testis, spleen and thymus. {ECO:0000269|PubMed:12941944, ECO:0000269|PubMed:14623122}.
• Sequence:

  MITVNPDGKIMVRRCLVTLRPFRLFVLGIGFFTLCFLMTSLGGQFSARRLGDSPFTIRTE
  VMGGPESRGVLRKMSDLLELMVKRMDALARLENSSELHRAGGDLHFPADRMPPGAGLMER
  IQAIAQNVSDIAVKVDQILRHSLLLHSKVSEGRRDQCEAPSDPKFPDCSGKVEWMRARWT
  SDPCYAFFGVDGTECSFLIYLSEVEWFCPPLPWRNQTAAQRAPKPLPKVQAVFRSNLSHL
  LDLMGSGKESLIFMKKRTKRLTAQWALAAQRLAQKLGATQRDQKQILVHIGFLTEESGDV
  FSPRVLKGGPLGEMVQWADILTALYVLGHGLRVTVSLKELQSNLGVPPGRGSCPLTMPLP
  FDLIYTDYHGLQQMKRHMGLSFKKYRCRIRVIDTFGTEPAYNHEEYATLHGYRTNWGYWN
  LNPKQFMTMFPHTPDNSFMGFVSEELNETEKRLIKGGKASNMAVVYGKEASIWKLQGKEK
  FLGILNKYMEIHGTVYYESQRPPEVPAFVKNHGLLPQPEFQQLLRKAKLFIGFGFPYEGP
  APLEAIANGCIFLQSRFSPPHSSLNHEFFRGKPTSREVFSQHPYAENFIGKPHVWTVDYN
  NSEEFEAAIKAIMRTQVDPYLPYEYTCEGMLERIHAYIQHQDFCRAPDPALPEAHAPQSP
  FVLAPNATHLEWARNTSLAPGAWPPAHALRAWLAVPGRACTDTCLDHGLICEPSFFPFLN
  SQDAFLKLQVPCDSTESEMNHLYPAFAQPGQECYLQKEPLLFSCAGSNTKYRRLCPCRDF
  RKGQVALCQGCL

• Sequence length: 792

Pathways

KEGG Pathway

N-Glycan biosynthesis

Mannose type O-glycan biosynthesis

Metabolic pathways

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations Show/Hide Unknown Diseases (7)
Phenotype Name	Clinical Significance	Source	Reference	Evidence Score
AUTISM SPECTRUM DISORDER	—	GWAS catalog	35215271	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
COLORECTAL CANCER	—	GWAS catalog	26621817	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
EMPHYSEMA	—	GWAS catalog	24383474	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ENDOMETRIAL NEOPLASM	—	GWAS catalog	26621817	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HYPOTENSION	—	GWAS catalog	39024449	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
POLYCYSTIC OVARY SYNDROME	—	CTD, Disgenet CTD, Disgenet	21411543	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
POST-TRAUMATIC STRESS DISORDER	—	GWAS catalog	33510476	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining Show/Hide Text Mining Associations (16)
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Brain Neoplasms	Brain Neoplasms	BEFREE	26794090		★☆☆☆☆ Found in Text Mining only
Carcinoma Transitional Cell	Transitional cell carcinoma	Pubtator	31805718	Associate	★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	10673297	Associate	★☆☆☆☆ Found in Text Mining only
Conventional (Clear Cell) Renal Cell Carcinoma	Renal Carcinoma	BEFREE	25630622		★☆☆☆☆ Found in Text Mining only
Ductal Breast Carcinoma	Breast Carcinoma	BEFREE	24966944		★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	Pubtator	17255279	Associate	★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	25232831		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of brain	Brain Neoplasms	BEFREE	26794090		★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	23107376, 25630622		★☆☆☆☆ Found in Text Mining only
Neuroblastoma	Neuroblastoma	BEFREE	16406367		★☆☆☆☆ Found in Text Mining only
Peritoneal Fibrosis	Peritoneal fibrosis	Pubtator	37335673	Associate	★☆☆☆☆ Found in Text Mining only
Polycystic Ovary Syndrome	Polycystic Ovary Syndrome	CTD_human_DG	21411543		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Prostatic Neoplasms	Prostatic neoplasm	Pubtator	35246070	Associate	★☆☆☆☆ Found in Text Mining only
Sclerocystic Ovaries	Sclerocystic Ovaries	CTD_human_DG	21411543		★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach neoplasms	Pubtator	23107376	Associate	★☆☆☆☆ Found in Text Mining only
Uveal melanoma	Uveal melanoma	Pubtator	18385798	Associate	★☆☆☆☆ Found in Text Mining only

Related Genes

Sort by: Blended Diseases Pathways Evidence source

ZMYM4 2 shared diseasesEndometrial neoplasms, Post-traumatic stress disorder 2 shared evidence sourcesGWAS catalog (Endometrial neoplasms), GWAS catalog (Post-traumatic stress disorder) Related via 2 shared diseases including Endometrial neoplasms, Post-traumatic stress disorder — evidence mostly GWAS catalog. SRSF10 2 shared diseasesEndometrial neoplasms, Polycystic ovary syndrome 2 shared evidence sourcesCTD (Polycystic ovary syndrome), Disgenet (Polycystic ovary syndrome) Related via 2 shared diseases including Endometrial neoplasms, Polycystic ovary syndrome — evidence mostly CTD. DMRTA1 2 shared diseasesEndometrial neoplasms, Post-traumatic stress disorder 2 shared evidence sourcesGWAS catalog (Endometrial neoplasms), GWAS catalog (Post-traumatic stress disorder) Related via 2 shared diseases including Endometrial neoplasms, Post-traumatic stress disorder — evidence mostly GWAS catalog. AKR1C1 2 shared diseasesEndometrial neoplasms, Polycystic ovary syndrome 2 shared evidence sourcesCTD (Polycystic ovary syndrome), Disgenet (Polycystic ovary syndrome) Related via 2 shared diseases including Endometrial neoplasms, Polycystic ovary syndrome — evidence mostly CTD. AKR1C3 2 shared diseasesEndometrial neoplasms, Polycystic ovary syndrome 2 shared evidence sourcesCTD (Polycystic ovary syndrome), Disgenet (Polycystic ovary syndrome) Related via 2 shared diseases including Endometrial neoplasms, Polycystic ovary syndrome — evidence mostly CTD.

Related Gene	Shared Diseases	Shared Disease Names	Shared Pathways	Shared Pathway Names	Shared Evidence Sources	Shared Evidence Names
ZMYM4	2	["Endometrial neoplasms","Post-traumatic stress disorder"]	0	[]	2	["GWAS catalog (Endometrial neoplasms)","GWAS catalog (Post-traumatic stress disorder)"]
SRSF10	2	["Endometrial neoplasms","Polycystic ovary syndrome"]	0	[]	2	["CTD (Polycystic ovary syndrome)","Disgenet (Polycystic ovary syndrome)"]
DMRTA1	2	["Endometrial neoplasms","Post-traumatic stress disorder"]	0	[]	2	["GWAS catalog (Endometrial neoplasms)","GWAS catalog (Post-traumatic stress disorder)"]
AKR1C1	2	["Endometrial neoplasms","Polycystic ovary syndrome"]	0	[]	2	["CTD (Polycystic ovary syndrome)","Disgenet (Polycystic ovary syndrome)"]
AKR1C3	2	["Endometrial neoplasms","Polycystic ovary syndrome"]	0	[]	2	["CTD (Polycystic ovary syndrome)","Disgenet (Polycystic ovary syndrome)"]

Diseases Linked via Similar Genes

Endometrial cancer Linked via 2 of 5 related genesZMYM4, DMRTA1 Major depressive disorder Linked via 2 of 5 related genesZMYM4, AKR1C3 Schizophrenia Linked via 2 of 5 related genesZMYM4, SRSF10 Obesity Linked via 2 of 5 related genesSRSF10, AKR1C3 Disorders of sex development Linked via 2 of 5 related genesAKR1C1, AKR1C3

Disease	Linked Via (Gene Count)	Linked Via (Gene Names)
Endometrial cancer	2	["ZMYM4","DMRTA1"]
Major depressive disorder	2	["ZMYM4","AKR1C3"]
Schizophrenia	2	["ZMYM4","SRSF10"]
Obesity	2	["SRSF10","AKR1C3"]
Disorders of sex development	2	["AKR1C1","AKR1C3"]