MCU (mitochondrial calcium uniporter)

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Gene miRNA Gene ontology Other IDs Protein Pathways Related genes Diseases linked via similar genes

Gene

• Entrez ID: 90550
• Gene name: Mitochondrial calcium uniporter
• Gene symbol: MCU
• Synonyms (NCBI Gene): C10orf42, CCDC109A, HsMCU
• Chromosome: 10
• Chromosome location: 10q22.1
• Summary: This gene encodes a calcium transporter that localizes to the mitochondrial inner membrane. The encoded protein interacts with mitochondrial calcium uptake 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]

miRNA Show/Hide all (215)

miRTarBase ID	miRNA	Experiments	Reference
MIRT005270	hsa-miR-16-5p	pSILAC	18668040
MIRT005270	hsa-miR-16-5p	Proteomics;Other	18668040
MIRT050443	hsa-miR-23a-3p	CLASH	23622248
MIRT047735	hsa-miR-10a-5p	CLASH	23622248
MIRT656403	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT656402	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT656401	hsa-miR-4716-5p	HITS-CLIP	23824327
MIRT656400	hsa-miR-1470	HITS-CLIP	23824327
MIRT656399	hsa-miR-4667-3p	HITS-CLIP	23824327
MIRT656398	hsa-miR-4780	HITS-CLIP	23824327
MIRT656397	hsa-miR-6780b-3p	HITS-CLIP	23824327
MIRT656396	hsa-miR-136-5p	HITS-CLIP	23824327
MIRT656395	hsa-miR-4469	HITS-CLIP	23824327
MIRT656394	hsa-miR-4287	HITS-CLIP	23824327
MIRT656393	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT656392	hsa-miR-2115-5p	HITS-CLIP	23824327
MIRT656391	hsa-miR-516a-3p	HITS-CLIP	23824327
MIRT656390	hsa-miR-516b-3p	HITS-CLIP	23824327
MIRT656389	hsa-miR-7162-5p	HITS-CLIP	23824327
MIRT656388	hsa-miR-3909	HITS-CLIP	23824327
MIRT656387	hsa-miR-6852-3p	HITS-CLIP	23824327
MIRT656386	hsa-miR-188-3p	HITS-CLIP	23824327
MIRT656385	hsa-miR-1260a	HITS-CLIP	23824327
MIRT656384	hsa-miR-1260b	HITS-CLIP	23824327
MIRT656383	hsa-miR-3156-3p	HITS-CLIP	23824327
MIRT656382	hsa-miR-623	HITS-CLIP	23824327
MIRT656381	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT656380	hsa-miR-515-5p	HITS-CLIP	23824327
MIRT656379	hsa-miR-519e-5p	HITS-CLIP	23824327
MIRT656378	hsa-miR-3977	HITS-CLIP	23824327
MIRT656377	hsa-miR-629-3p	HITS-CLIP	23824327
MIRT656403	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT656402	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT656401	hsa-miR-4716-5p	HITS-CLIP	23824327
MIRT656400	hsa-miR-1470	HITS-CLIP	23824327
MIRT656399	hsa-miR-4667-3p	HITS-CLIP	23824327
MIRT656398	hsa-miR-4780	HITS-CLIP	23824327
MIRT656397	hsa-miR-6780b-3p	HITS-CLIP	23824327
MIRT656396	hsa-miR-136-5p	HITS-CLIP	23824327
MIRT656395	hsa-miR-4469	HITS-CLIP	23824327
MIRT656394	hsa-miR-4287	HITS-CLIP	23824327
MIRT656393	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT656392	hsa-miR-2115-5p	HITS-CLIP	23824327
MIRT656391	hsa-miR-516a-3p	HITS-CLIP	23824327
MIRT656390	hsa-miR-516b-3p	HITS-CLIP	23824327
MIRT656389	hsa-miR-7162-5p	HITS-CLIP	23824327
MIRT656388	hsa-miR-3909	HITS-CLIP	23824327
MIRT656387	hsa-miR-6852-3p	HITS-CLIP	23824327
MIRT656386	hsa-miR-188-3p	HITS-CLIP	23824327
MIRT656385	hsa-miR-1260a	HITS-CLIP	23824327
MIRT656384	hsa-miR-1260b	HITS-CLIP	23824327
MIRT656383	hsa-miR-3156-3p	HITS-CLIP	23824327
MIRT656382	hsa-miR-623	HITS-CLIP	23824327
MIRT656381	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT656380	hsa-miR-515-5p	HITS-CLIP	23824327
MIRT656379	hsa-miR-519e-5p	HITS-CLIP	23824327
MIRT656378	hsa-miR-3977	HITS-CLIP	23824327
MIRT656377	hsa-miR-629-3p	HITS-CLIP	23824327
MIRT1138368	hsa-miR-1200	CLIP-seq
MIRT1138369	hsa-miR-1207-5p	CLIP-seq
MIRT1138370	hsa-miR-124	CLIP-seq
MIRT1138371	hsa-miR-1260	CLIP-seq
MIRT1138372	hsa-miR-1289	CLIP-seq
MIRT1138373	hsa-miR-15a	CLIP-seq
MIRT1138374	hsa-miR-15b	CLIP-seq
MIRT1138375	hsa-miR-16	CLIP-seq
MIRT1138376	hsa-miR-1913	CLIP-seq
MIRT1138377	hsa-miR-195	CLIP-seq
MIRT1138378	hsa-miR-2115	CLIP-seq
MIRT1138379	hsa-miR-217	CLIP-seq
MIRT1138380	hsa-miR-2681	CLIP-seq
MIRT1138381	hsa-miR-30a	CLIP-seq
MIRT1138382	hsa-miR-30b	CLIP-seq
MIRT1138383	hsa-miR-30c	CLIP-seq
MIRT1138384	hsa-miR-30d	CLIP-seq
MIRT1138385	hsa-miR-30e	CLIP-seq
MIRT1138386	hsa-miR-3140-3p	CLIP-seq
MIRT1138387	hsa-miR-3173-3p	CLIP-seq
MIRT1138388	hsa-miR-3180-5p	CLIP-seq
MIRT1138389	hsa-miR-3198	CLIP-seq
MIRT1138390	hsa-miR-324-3p	CLIP-seq
MIRT1138391	hsa-miR-325	CLIP-seq
MIRT1138392	hsa-miR-329	CLIP-seq
MIRT1138393	hsa-miR-330-3p	CLIP-seq
MIRT1138394	hsa-miR-377	CLIP-seq
MIRT1138395	hsa-miR-3908	CLIP-seq
MIRT1138396	hsa-miR-3936	CLIP-seq
MIRT1138397	hsa-miR-3942-5p	CLIP-seq
MIRT1138398	hsa-miR-424	CLIP-seq
MIRT1138399	hsa-miR-4254	CLIP-seq
MIRT1138400	hsa-miR-4294	CLIP-seq
MIRT1138401	hsa-miR-4309	CLIP-seq
MIRT1138402	hsa-miR-4433	CLIP-seq
MIRT1138403	hsa-miR-4524	CLIP-seq
MIRT1138404	hsa-miR-4662a-5p	CLIP-seq
MIRT1138405	hsa-miR-4703-5p	CLIP-seq
MIRT1138406	hsa-miR-4711-5p	CLIP-seq
MIRT1138407	hsa-miR-4722-3p	CLIP-seq
MIRT1138408	hsa-miR-4722-5p	CLIP-seq
MIRT1138409	hsa-miR-4733-5p	CLIP-seq
MIRT1138410	hsa-miR-4736	CLIP-seq
MIRT1138411	hsa-miR-4738-3p	CLIP-seq
MIRT1138412	hsa-miR-4749-3p	CLIP-seq
MIRT1138413	hsa-miR-4763-3p	CLIP-seq
MIRT1138414	hsa-miR-4766-3p	CLIP-seq
MIRT1138415	hsa-miR-4793-5p	CLIP-seq
MIRT1138416	hsa-miR-488	CLIP-seq
MIRT1138417	hsa-miR-497	CLIP-seq
MIRT1138418	hsa-miR-501-5p	CLIP-seq
MIRT1138419	hsa-miR-503	CLIP-seq
MIRT1138420	hsa-miR-506	CLIP-seq
MIRT1138421	hsa-miR-520a-5p	CLIP-seq
MIRT1138422	hsa-miR-525-5p	CLIP-seq
MIRT1138423	hsa-miR-580	CLIP-seq
MIRT1138424	hsa-miR-587	CLIP-seq
MIRT1138425	hsa-miR-609	CLIP-seq
MIRT1138426	hsa-miR-619	CLIP-seq
MIRT1138427	hsa-miR-626	CLIP-seq
MIRT1138428	hsa-miR-628-3p	CLIP-seq
MIRT1138429	hsa-miR-629	CLIP-seq
MIRT1138430	hsa-miR-640	CLIP-seq
MIRT1138431	hsa-miR-646	CLIP-seq
MIRT2039243	hsa-miR-1237	CLIP-seq
MIRT2039244	hsa-miR-1248	CLIP-seq
MIRT2039245	hsa-miR-136	CLIP-seq
MIRT2039246	hsa-miR-3934	CLIP-seq
MIRT2039247	hsa-miR-4326	CLIP-seq
MIRT2039248	hsa-miR-4470	CLIP-seq
MIRT2039249	hsa-miR-4477a	CLIP-seq
MIRT2039250	hsa-miR-4714-3p	CLIP-seq
MIRT2039251	hsa-miR-4731-3p	CLIP-seq
MIRT2039252	hsa-miR-4801	CLIP-seq
MIRT2039253	hsa-miR-485-3p	CLIP-seq
MIRT1138421	hsa-miR-520a-5p	CLIP-seq
MIRT1138422	hsa-miR-525-5p	CLIP-seq
MIRT2039254	hsa-miR-548an	CLIP-seq
MIRT2039255	hsa-miR-552	CLIP-seq
MIRT2039256	hsa-miR-561	CLIP-seq
MIRT1138430	hsa-miR-640	CLIP-seq
MIRT2039257	hsa-miR-944	CLIP-seq
MIRT1138368	hsa-miR-1200	CLIP-seq
MIRT1138369	hsa-miR-1207-5p	CLIP-seq
MIRT2039243	hsa-miR-1237	CLIP-seq
MIRT2039244	hsa-miR-1248	CLIP-seq
MIRT2269314	hsa-miR-1252	CLIP-seq
MIRT2269315	hsa-miR-1293	CLIP-seq
MIRT2269316	hsa-miR-1299	CLIP-seq
MIRT2269317	hsa-miR-143	CLIP-seq
MIRT2269318	hsa-miR-149	CLIP-seq
MIRT1138373	hsa-miR-15a	CLIP-seq
MIRT1138374	hsa-miR-15b	CLIP-seq
MIRT1138375	hsa-miR-16	CLIP-seq
MIRT1138377	hsa-miR-195	CLIP-seq
MIRT2269319	hsa-miR-2682	CLIP-seq
MIRT2269320	hsa-miR-3064-5p	CLIP-seq
MIRT1138381	hsa-miR-30a	CLIP-seq
MIRT1138382	hsa-miR-30b	CLIP-seq
MIRT1138383	hsa-miR-30c	CLIP-seq
MIRT1138384	hsa-miR-30d	CLIP-seq
MIRT1138385	hsa-miR-30e	CLIP-seq
MIRT2269321	hsa-miR-3126-3p	CLIP-seq
MIRT2269322	hsa-miR-3165	CLIP-seq
MIRT2269323	hsa-miR-3176	CLIP-seq
MIRT1138393	hsa-miR-330-3p	CLIP-seq
MIRT2269324	hsa-miR-3652	CLIP-seq
MIRT2269325	hsa-miR-3714	CLIP-seq
MIRT1138394	hsa-miR-377	CLIP-seq
MIRT2269326	hsa-miR-3922-3p	CLIP-seq
MIRT2039246	hsa-miR-3934	CLIP-seq
MIRT1138398	hsa-miR-424	CLIP-seq
MIRT2269327	hsa-miR-4302	CLIP-seq
MIRT2039247	hsa-miR-4326	CLIP-seq
MIRT2269328	hsa-miR-4419a	CLIP-seq
MIRT2269329	hsa-miR-4430	CLIP-seq
MIRT1138402	hsa-miR-4433	CLIP-seq
MIRT2269330	hsa-miR-4434	CLIP-seq
MIRT2039248	hsa-miR-4470	CLIP-seq
MIRT2269331	hsa-miR-4483	CLIP-seq
MIRT2269332	hsa-miR-449c	CLIP-seq
MIRT2269333	hsa-miR-4505	CLIP-seq
MIRT2269334	hsa-miR-4510	CLIP-seq
MIRT2269335	hsa-miR-4516	CLIP-seq
MIRT1138403	hsa-miR-4524	CLIP-seq
MIRT2269336	hsa-miR-4640-3p	CLIP-seq
MIRT2269337	hsa-miR-4651	CLIP-seq
MIRT1138404	hsa-miR-4662a-5p	CLIP-seq
MIRT2269338	hsa-miR-4717-3p	CLIP-seq
MIRT1138408	hsa-miR-4722-5p	CLIP-seq
MIRT1138410	hsa-miR-4736	CLIP-seq
MIRT1138413	hsa-miR-4763-3p	CLIP-seq
MIRT2269339	hsa-miR-4770	CLIP-seq
MIRT2269340	hsa-miR-4794	CLIP-seq
MIRT1138417	hsa-miR-497	CLIP-seq
MIRT1138419	hsa-miR-503	CLIP-seq
MIRT2039254	hsa-miR-548an	CLIP-seq
MIRT2039255	hsa-miR-552	CLIP-seq
MIRT2269341	hsa-miR-608	CLIP-seq
MIRT2269342	hsa-miR-637	CLIP-seq
MIRT1138431	hsa-miR-646	CLIP-seq
MIRT2039246	hsa-miR-3934	CLIP-seq
MIRT2039247	hsa-miR-4326	CLIP-seq
MIRT2039248	hsa-miR-4470	CLIP-seq
MIRT2039254	hsa-miR-548an	CLIP-seq
MIRT2039255	hsa-miR-552	CLIP-seq
MIRT1138368	hsa-miR-1200	CLIP-seq
MIRT2039246	hsa-miR-3934	CLIP-seq
MIRT2039247	hsa-miR-4326	CLIP-seq
MIRT2039248	hsa-miR-4470	CLIP-seq
MIRT2039254	hsa-miR-548an	CLIP-seq
MIRT2039255	hsa-miR-552	CLIP-seq
MIRT2465620	hsa-miR-1914	CLIP-seq
MIRT1138388	hsa-miR-3180-5p	CLIP-seq
MIRT1138421	hsa-miR-520a-5p	CLIP-seq
MIRT1138422	hsa-miR-525-5p	CLIP-seq
MIRT2465621	hsa-miR-548u	CLIP-seq

Gene ontology (GO) Show/Hide all (55)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005262	Function	Calcium channel activity	IBA
GO:0005262	Function	Calcium channel activity	IDA	21685888, 24560927, 29954988, 29995857, 30638448, 31080062, 32494073, 33296646
GO:0005262	Function	Calcium channel activity	IEA
GO:0005262	Function	Calcium channel activity	IMP	23755363
GO:0005515	Function	Protein binding	IPI	21685886, 23101630, 23178883, 24430870, 26387864, 27099988, 27184846, 30454562, 30638448, 32494073, 33961781
GO:0005739	Component	Mitochondrion	HTP	34800366
GO:0005739	Component	Mitochondrion	IDA
GO:0005739	Component	Mitochondrion	IEA
GO:0005743	Component	Mitochondrial inner membrane	IDA	31080062
GO:0005743	Component	Mitochondrial inner membrane	IDA	21685886, 21685888, 23755363, 24231807, 27099988, 32494073
GO:0005743	Component	Mitochondrial inner membrane	IEA
GO:0005743	Component	Mitochondrial inner membrane	NAS	24514027, 31533452, 31862210
GO:0005743	Component	Mitochondrial inner membrane	TAS
GO:0006091	Process	Generation of precursor metabolites and energy	IEA
GO:0006811	Process	Monoatomic ion transport	IEA
GO:0006816	Process	Calcium ion transport	IEA
GO:0006851	Process	Mitochondrial calcium ion transmembrane transport	IDA	21685888, 24560927
GO:0006851	Process	Mitochondrial calcium ion transmembrane transport	IEA
GO:0006851	Process	Mitochondrial calcium ion transmembrane transport	IMP	21685886, 23755363
GO:0008283	Process	Cell population proliferation	IEA
GO:0015292	Function	Uniporter activity	IBA
GO:0015292	Function	Uniporter activity	IDA	21685886, 21685888, 24560927
GO:0015292	Function	Uniporter activity	IEA
GO:0015292	Function	Uniporter activity	IMP	23755363
GO:0016020	Component	Membrane	IEA
GO:0016477	Process	Cell migration	IEA
GO:0019722	Process	Calcium-mediated signaling	IDA	21685886, 21685888
GO:0032024	Process	Positive regulation of insulin secretion	IMP	22829870
GO:0034220	Process	Monoatomic ion transmembrane transport	IEA
GO:0034704	Component	Calcium channel complex	IDA	23755363
GO:0034704	Component	Calcium channel complex	IEA
GO:0034704	Component	Calcium channel complex	ISS
GO:0036444	Process	Calcium import into the mitochondrion	IBA
GO:0036444	Process	Calcium import into the mitochondrion	IDA	22925203, 23755363, 29954988, 29995857, 30454562, 31080062, 32494073, 32762847, 33296646
GO:0036444	Process	Calcium import into the mitochondrion	IMP	23755363
GO:0036444	Process	Calcium import into the mitochondrion	NAS	24514027, 31533452, 31862210
GO:0042593	Process	Glucose homeostasis	IMP	22829870
GO:0042802	Function	Identical protein binding	IPI	21685886, 29995857
GO:0051259	Process	Protein complex oligomerization	IDA	21685886
GO:0051560	Process	Mitochondrial calcium ion homeostasis	IBA
GO:0051560	Process	Mitochondrial calcium ion homeostasis	IDA	32494073
GO:0051560	Process	Mitochondrial calcium ion homeostasis	IEA
GO:0051560	Process	Mitochondrial calcium ion homeostasis	NAS	24514027, 31533452, 31862210
GO:0051561	Process	Positive regulation of mitochondrial calcium ion concentration	IDA	21685888, 24560927
GO:0051561	Process	Positive regulation of mitochondrial calcium ion concentration	IEA
GO:0051561	Process	Positive regulation of mitochondrial calcium ion concentration	IMP	21685886, 23755363
GO:0070588	Process	Calcium ion transmembrane transport	IEA
GO:0072732	Process	Cellular response to calcium ion starvation	IMP	32494073
GO:0090023	Process	Positive regulation of neutrophil chemotaxis	IMP	28388446
GO:0090141	Process	Positive regulation of mitochondrial fission	IMP	28388446
GO:1990246	Component	Uniplex complex	IBA
GO:1990246	Component	Uniplex complex	IDA	24231807, 24560927, 31080062, 32315830, 32762847, 32862359
GO:1990246	Component	Uniplex complex	IPI	32494073
GO:1990246	Component	Uniplex complex	ISS
GO:1990246	Component	Uniplex complex	NAS	31533452

Other IDs

• MIM: 614197
• HGNC: 23526
• e!Ensembl: ENSG00000156026

Protein

• UniProt ID: Q8NE86
• Protein name: Calcium uniporter protein, mitochondrial (HsMCU) (Coiled-coil domain-containing protein 109A)
• Protein function: Channel-forming and calcium-conducting subunit of the mitochondrial inner membrane calcium uniporter complex (uniplex), which mediates calcium uptake into the mitochondrial matrix (PubMed:21685886, PubMed:21685888, PubMed:22822213, PubMed:228298
• PDB: 4XSJ , 4XTB , 5BZ6 , 5KUE , 5KUG , 5KUI , 5KUJ , 6JG0 , 6K7X , 6K7Y , 6KVX , 6O58 , 6O5B , 6WDN , 6WDO , 6XJV , 6XJX , 8URG
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF04678	MCU	118 → 320	Mitochondrial calcium uniporter	Family

• Sequence:

  MAAAAGRSLLLLLSSRGGGGGGAGGCGALTAGCFPGLGVSRHRQQQHHRTVHQRIASWQN
  LGAVYCSTVVPSDDVTVVYQNGLPVISVRLPSRRERCQFTLKPISDSVGVFLRQLQEEDR
  GIDRVAIYSPDGVRVAASTGIDLLLLDDFKLVINDLTYHVRPPKRDLLSHENAATLNDVK
  TLVQQLYTTLCIEQHQLNKERELIERLEDLKEQLAPLEKVRIEISRKAEKRTTLVLWGGL
  AYMATQFGILARLTWWEYSWDIMEPVTYFITYGSAMAMYAYFVMTRQEYVYPEARDRQYL
  LFFHKGAKKSRFDLEKYNQLKDAIAQAEMDLKRLRDPLQVHLPLRQIGEKD

• Sequence length: 351

Pathways

KEGG Pathway	Reactome Pathway
Calcium signaling pathway	Mitochondrial calcium ion transport
Cellular senescence	Processing of SMDT1
NOD-like receptor signaling pathway
Alzheimer disease
Parkinson disease
Amyotrophic lateral sclerosis
Spinocerebellar ataxia
Prion disease
Pathways of neurodegeneration - multiple diseases

Related Genes

Sort by: Blended Diseases Pathways Evidence source

VDAC2 6 shared pathwaysCalcium signaling pathway, Cellular senescence, NOD-like receptor signaling pathway, Parkinson disease, Spinocerebellar ataxia, Prion disease Related via 6 shared pathways including Calcium signaling pathway, Cellular senescence. SLC25A31 5 shared pathwaysCalcium signaling pathway, Cellular senescence, Parkinson disease, Spinocerebellar ataxia, Prion disease Related via 5 shared pathways including Calcium signaling pathway, Cellular senescence. VDAC3 6 shared pathwaysCalcium signaling pathway, Cellular senescence, NOD-like receptor signaling pathway, Parkinson disease, Spinocerebellar ataxia, Prion disease Related via 6 shared pathways including Calcium signaling pathway, Cellular senescence. PPIF 4 shared pathwaysCalcium signaling pathway, Parkinson disease, Spinocerebellar ataxia, Prion disease Related via 4 shared pathways including Calcium signaling pathway, Parkinson disease. VDAC1 6 shared pathwaysCalcium signaling pathway, Cellular senescence, NOD-like receptor signaling pathway, Parkinson disease, Spinocerebellar ataxia, Prion disease Related via 6 shared pathways including Calcium signaling pathway, Cellular senescence.

Related Gene	Shared Diseases	Shared Disease Names	Shared Pathways	Shared Pathway Names	Shared Evidence Sources	Shared Evidence Names
VDAC2	0	[]	6	["Calcium signaling pathway","Cellular senescence","NOD-like receptor signaling pathway","Parkinson disease","Spinocerebellar ataxia","Prion disease"]	0	[]
SLC25A31	0	[]	5	["Calcium signaling pathway","Cellular senescence","Parkinson disease","Spinocerebellar ataxia","Prion disease"]	0	[]
VDAC3	0	[]	6	["Calcium signaling pathway","Cellular senescence","NOD-like receptor signaling pathway","Parkinson disease","Spinocerebellar ataxia","Prion disease"]	0	[]
PPIF	0	[]	4	["Calcium signaling pathway","Parkinson disease","Spinocerebellar ataxia","Prion disease"]	0	[]
VDAC1	0	[]	6	["Calcium signaling pathway","Cellular senescence","NOD-like receptor signaling pathway","Parkinson disease","Spinocerebellar ataxia","Prion disease"]	0	[]

Diseases Linked via Similar Genes

Diabetic neuropathy Linked via 2 of 5 related genesVDAC2, VDAC1 Epilepsy Linked via 2 of 5 related genesVDAC2, VDAC1 Squamous cell carcinoma Linked via 1 of 5 related genesVDAC2 Mouth neoplasms Linked via 1 of 5 related genesVDAC2 Osteoarthritis Linked via 1 of 5 related genesVDAC2

Disease	Linked Via (Gene Count)	Linked Via (Gene Names)
Diabetic neuropathy	2	["VDAC2","VDAC1"]
Epilepsy	2	["VDAC2","VDAC1"]
Squamous cell carcinoma	1	["VDAC2"]
Mouth neoplasms	1	["VDAC2"]
Osteoarthritis	1	["VDAC2"]