H3C14 (H3 clustered histone 14)

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Gene Gene information from NCBI Gene database.
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Entrez ID 126961
Gene name H3 clustered histone 14
Gene symbol H3C14
Synonyms (NCBI Gene)
H3H3.2H3/MH3C13H3C15H3F2H3FMH3FNHIST2H3C
Chromosome 1
Chromosome location 1q21.2
Summary Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the f
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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GO ID Ontology Definition Evidence Reference
GO:0000122 Process Negative regulation of transcription by RNA polymerase II IEA
GO:0000785 Component Chromatin IEA
GO:0000786 Component Nucleosome IDA 21636898, 25615412
GO:0000786 Component Nucleosome IEA
GO:0000786 Component Nucleosome IPI 26694698
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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MIM HGNC e!Ensembl
142780 20503 ENSG00000203811
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
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KEGG Pathway Reactome Pathway
Neutrophil extracellular trap formation Interleukin-7 signaling
Alcoholism Formation of the beta-catenin:TCF transactivating complex
Shigellosis PRC2 methylates histones and DNA
Transcriptional misregulation in cancer Condensation of Prophase Chromosomes
Systemic lupus erythematosus Oxidative Stress Induced Senescence
  Senescence-Associated Secretory Phenotype (SASP)
  HDACs deacetylate histones
  PKMTs methylate histone lysines
  HDMs demethylate histones
  HATs acetylate histones
  RMTs methylate histone arginines
  Chromatin modifying enzymes
  SIRT1 negatively regulates rRNA expression
  NoRC negatively regulates rRNA expression
  B-WICH complex positively regulates rRNA expression
  Transcriptional regulation by small RNAs
  Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
  RNA Polymerase I Promoter Opening
  RNA Polymerase I Promoter Escape
  RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
  Estrogen-dependent gene expression
  HCMV Early Events
  HCMV Late Events
  Amyloid fiber formation
  Factors involved in megakaryocyte development and platelet production
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H3C15 30 shared pathwaysNeutrophil extracellular trap formation, Alcoholism, Shigellosis, Transcriptional misregulation in cancer, Systemic lupus erythematosus, Factors involved in megakaryocyte development and platelet production, Condensation of Prophase Chromosomes, HCMV Late Events, Oxidative Stress Induced Senescence, Amyloid fiber formation, HCMV Early Events, Senescence-Associated Secretory Phenotype (SASP) +18 more Related via 30 shared pathways including Neutrophil extracellular trap formation, Alcoholism. H3C13 30 shared pathwaysNeutrophil extracellular trap formation, Alcoholism, Shigellosis, Transcriptional misregulation in cancer, Systemic lupus erythematosus, Factors involved in megakaryocyte development and platelet production, Condensation of Prophase Chromosomes, HCMV Late Events, Oxidative Stress Induced Senescence, Amyloid fiber formation, HCMV Early Events, Senescence-Associated Secretory Phenotype (SASP) +18 more Related via 30 shared pathways including Neutrophil extracellular trap formation, Alcoholism. H3C1 30 shared pathwaysNeutrophil extracellular trap formation, Alcoholism, Shigellosis, Transcriptional misregulation in cancer, Systemic lupus erythematosus, Factors involved in megakaryocyte development and platelet production, Condensation of Prophase Chromosomes, HCMV Late Events, Oxidative Stress Induced Senescence, Amyloid fiber formation, HCMV Early Events, Senescence-Associated Secretory Phenotype (SASP) +18 more Related via 30 shared pathways including Neutrophil extracellular trap formation, Alcoholism. H3C4 30 shared pathwaysNeutrophil extracellular trap formation, Alcoholism, Shigellosis, Transcriptional misregulation in cancer, Systemic lupus erythematosus, Factors involved in megakaryocyte development and platelet production, Condensation of Prophase Chromosomes, HCMV Late Events, Oxidative Stress Induced Senescence, Amyloid fiber formation, HCMV Early Events, Senescence-Associated Secretory Phenotype (SASP) +18 more Related via 30 shared pathways including Neutrophil extracellular trap formation, Alcoholism. H3C3 30 shared pathwaysNeutrophil extracellular trap formation, Alcoholism, Shigellosis, Transcriptional misregulation in cancer, Systemic lupus erythematosus, Factors involved in megakaryocyte development and platelet production, Condensation of Prophase Chromosomes, HCMV Late Events, Oxidative Stress Induced Senescence, Amyloid fiber formation, HCMV Early Events, Senescence-Associated Secretory Phenotype (SASP) +18 more Related via 30 shared pathways including Neutrophil extracellular trap formation, Alcoholism.
Insomnia Linked via 1 of 5 related genesH3C4 Major depressive disorder Linked via 1 of 5 related genesH3C4 Schizophrenia Linked via 1 of 5 related genesH3C4