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Gene Gene information from NCBI Gene database.
Entrez ID 23105
Gene name Follistatin like 4
Gene symbol FSTL4
Synonyms (NCBI Gene)
-
Chromosome 5
Chromosome location 5q31.1
miRNA miRNA information provided by mirtarbase database.
236 Show/Hide all (236)
miRTarBase ID miRNA Experiments Reference
MIRT658054 hsa-miR-6792-5p HITS-CLIP 23824327
MIRT615983 hsa-miR-183-3p HITS-CLIP 23824327
MIRT615982 hsa-miR-4452 HITS-CLIP 23824327
MIRT658053 hsa-miR-4503 HITS-CLIP 23824327
MIRT658052 hsa-miR-7856-5p HITS-CLIP 23824327
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
12 Show/Hide all (12)
GO ID Ontology Definition Evidence Reference
GO:0005509 Function Calcium ion binding IEA
GO:0005576 Component Extracellular region IBA
GO:0005576 Component Extracellular region IEA
GO:0030141 Component Secretory granule IEA
GO:0030154 Process Cell differentiation IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q6MZW2
Protein name Follistatin-related protein 4 (Follistatin-like protein 4)
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF07648 Kazal_2 87 → 133 Kazal-type serine protease inhibitor domain Domain
PF13927 Ig_3 340 → 417 Domain
PF13927 Ig_3 250 → 324 Domain
Sequence
MKPGGFWLHLTLLGASLPAALGWMDPGTSRGPDVGVGESQAEEPRSFEVTRREGLSSHNE
LLASCGKKFCSRGSRCVLSRKTGEPECQCLEACRPSYVPVCGSDGRFYENHCKLHRAACL
LGKRITVIHSKDC
FLKGDTCTMAGYARLKNVLLALQTRLQPLQEGDSRQDPASQKRLLVE
SLFRDLDADGNGHLSSSELAQHVLKKQDLDEDLLGCSPGDLLRFDDYNSDSSLTLREFYM
AFQVVQLSLAPEDRVSVTTVTVGLSTVLTCAVHGDLRPPIIWKRNGLTLNFLDLEDINDF
GEDDSLYITKVTTIHMGNYTCHAS
GHEQLFQTHVLQVNVPPVIRVYPESQAQEPGVAASL
RCHAEGIPMPRITWLKNGVDVSTQMSKQLSLLANGSELHISSVRYEDTGAYTCIAKN
EVG
VDEDISSLFIEDSARKTLANILWREEGLSVGNMFYVFSDDGIIVIHPVDCEIQRHLKPTE
KIFMSYEEICPQREKNATQPCQWVSAVNVRNRYIYVAQPALSRVLVVDIQAQKVLQSIGV
DPLPAKLSYDKSHDQVWVLSWGDVHKSRPSLQVITEASTGQSQHLIRTPFAGVDDFFIPP
TNLIINHIRFGFIFNKSDPAVHKVDLETMMPLKTIGLHHHGCVPQAMAHTHLGGYFFIQC
RQDSPASAARQLLVDSVTDSVLGPNGDVTGTPHTSPDGRFIVSAAADSPWLHVQEITVRG
EIQTLYDLQINSGISDLAFQRSFTESNQYNIYAALHTEPDLLFLELSTGKVGMLKNLKEP
PAGPAQPWGGTHRIMRDSGLFGQYLLTPARESLFLINGRQNTLRCEVSGIKGGTTVVWVG
EV
Sequence length 842
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
18
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Show/Hide Unknown Diseases (18)
Phenotype Name Clinical Significance Source Reference Evidence Score
ATTENTION DEFICIT HYPERACTIVITY DISORDER — GWAS catalog 18951430
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
CONDUCT DISORDER — GWAS catalog 18951430
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
ENDOMETRIOSIS — GWAS catalog 32121467
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
GOUT — GWAS catalog 22179738
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
HYPERTENSION — GWAS catalog 22384028
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text Mining Disease associations identified through text mining
Show/Hide Text Mining Associations (7)
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Arthritis, Gouty Gouty arthritis GWASCAT_DG 22179738
★★★★★
★☆☆☆☆
Found in Text Mining only
Colorectal Neoplasms Colorectal neoplasm Pubtator 39930364 Associate
★★★★★
★☆☆☆☆
Found in Text Mining only
Gout Gout GWASCAT_DG 22179738
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Major Depressive Disorder Mental Depression GWASCAT_DG 27622933
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Mood Disorders Mood Disorder GWASCAT_DG 27622933
★★★★★
★☆☆☆☆
Found in Text Mining only
Pancreatic Neoplasms Pancreatic neoplasm Pubtator 30747226 Associate
★★★★★
★☆☆☆☆
Found in Text Mining only
Stroke Stroke Pubtator 19023099 Associate
★★★★★
★☆☆☆☆
Found in Text Mining only