AACS (acetoacetyl-CoA synthetase)

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Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases Related genes Diseases linked via similar genes

Gene

• Entrez ID: 65985
• Gene name: Acetoacetyl-CoA synthetase
• Gene symbol: AACS
• Synonyms (NCBI Gene): ACSF1, SUR-5
• Chromosome: 12
• Chromosome location: 12q24.31

miRNA Show/Hide all (223)

miRTarBase ID	miRNA	Experiments	Reference
MIRT003093	hsa-miR-122-5p	Luciferase reporter assay, qRT-PCR	19296470
MIRT045810	hsa-miR-191-5p	CLASH	23622248
MIRT037034	hsa-miR-877-3p	CLASH	23622248
MIRT531947	hsa-miR-3614-5p	PAR-CLIP	22012620
MIRT531946	hsa-miR-589-3p	PAR-CLIP	22012620
MIRT531945	hsa-miR-6793-3p	PAR-CLIP	22012620
MIRT531944	hsa-miR-1470	PAR-CLIP	22012620
MIRT531943	hsa-miR-4667-3p	PAR-CLIP	22012620
MIRT531942	hsa-miR-4466	PAR-CLIP	22012620
MIRT531941	hsa-miR-675-5p	PAR-CLIP	22012620
MIRT531947	hsa-miR-3614-5p	PAR-CLIP	22012620
MIRT531946	hsa-miR-589-3p	PAR-CLIP	22012620
MIRT531945	hsa-miR-6793-3p	PAR-CLIP	22012620
MIRT531944	hsa-miR-1470	PAR-CLIP	22012620
MIRT531943	hsa-miR-4667-3p	PAR-CLIP	22012620
MIRT531942	hsa-miR-4466	PAR-CLIP	22012620
MIRT531941	hsa-miR-675-5p	PAR-CLIP	22012620
MIRT756646	hsa-miR-1243	CLIP-seq
MIRT756647	hsa-miR-125a-5p	CLIP-seq
MIRT756648	hsa-miR-125b	CLIP-seq
MIRT756649	hsa-miR-1276	CLIP-seq
MIRT756650	hsa-miR-137	CLIP-seq
MIRT756651	hsa-miR-153	CLIP-seq
MIRT756652	hsa-miR-19a	CLIP-seq
MIRT756653	hsa-miR-19b	CLIP-seq
MIRT756654	hsa-miR-25	CLIP-seq
MIRT756655	hsa-miR-3126-5p	CLIP-seq
MIRT756656	hsa-miR-3163	CLIP-seq
MIRT756657	hsa-miR-32	CLIP-seq
MIRT756658	hsa-miR-320a	CLIP-seq
MIRT756659	hsa-miR-320b	CLIP-seq
MIRT756660	hsa-miR-320c	CLIP-seq
MIRT756661	hsa-miR-320d	CLIP-seq
MIRT756662	hsa-miR-342-5p	CLIP-seq
MIRT756663	hsa-miR-363	CLIP-seq
MIRT756664	hsa-miR-3654	CLIP-seq
MIRT756665	hsa-miR-367	CLIP-seq
MIRT756666	hsa-miR-3910	CLIP-seq
MIRT756667	hsa-miR-4278	CLIP-seq
MIRT756668	hsa-miR-4282	CLIP-seq
MIRT756669	hsa-miR-4311	CLIP-seq
MIRT756670	hsa-miR-4319	CLIP-seq
MIRT756671	hsa-miR-4419a	CLIP-seq
MIRT756672	hsa-miR-4429	CLIP-seq
MIRT756673	hsa-miR-448	CLIP-seq
MIRT756674	hsa-miR-4495	CLIP-seq
MIRT756675	hsa-miR-4502	CLIP-seq
MIRT756676	hsa-miR-4510	CLIP-seq
MIRT756677	hsa-miR-4664-5p	CLIP-seq
MIRT756678	hsa-miR-4668-5p	CLIP-seq
MIRT756679	hsa-miR-4695-3p	CLIP-seq
MIRT756680	hsa-miR-4725-5p	CLIP-seq
MIRT756681	hsa-miR-4729	CLIP-seq
MIRT756682	hsa-miR-4760-3p	CLIP-seq
MIRT756683	hsa-miR-4768-3p	CLIP-seq
MIRT756684	hsa-miR-486-5p	CLIP-seq
MIRT756685	hsa-miR-494	CLIP-seq
MIRT756686	hsa-miR-504	CLIP-seq
MIRT756687	hsa-miR-544b	CLIP-seq
MIRT756688	hsa-miR-548an	CLIP-seq
MIRT756689	hsa-miR-570	CLIP-seq
MIRT756690	hsa-miR-583	CLIP-seq
MIRT756691	hsa-miR-622	CLIP-seq
MIRT756692	hsa-miR-711	CLIP-seq
MIRT756693	hsa-miR-92a	CLIP-seq
MIRT756694	hsa-miR-92b	CLIP-seq
MIRT1921846	hsa-miR-1229	CLIP-seq
MIRT1921847	hsa-miR-128	CLIP-seq
MIRT1921848	hsa-miR-140-3p	CLIP-seq
MIRT1921849	hsa-miR-197	CLIP-seq
MIRT1921850	hsa-miR-4639-3p	CLIP-seq
MIRT1921851	hsa-miR-603	CLIP-seq
MIRT1923137	hsa-miR-1302	CLIP-seq
MIRT1923138	hsa-miR-15a	CLIP-seq
MIRT1923139	hsa-miR-15b	CLIP-seq
MIRT1923140	hsa-miR-16	CLIP-seq
MIRT1923141	hsa-miR-195	CLIP-seq
MIRT756658	hsa-miR-320a	CLIP-seq
MIRT756659	hsa-miR-320b	CLIP-seq
MIRT756660	hsa-miR-320c	CLIP-seq
MIRT756661	hsa-miR-320d	CLIP-seq
MIRT1923142	hsa-miR-374a	CLIP-seq
MIRT1923143	hsa-miR-374b	CLIP-seq
MIRT1923144	hsa-miR-424	CLIP-seq
MIRT1923145	hsa-miR-4298	CLIP-seq
MIRT756672	hsa-miR-4429	CLIP-seq
MIRT1923146	hsa-miR-4524	CLIP-seq
MIRT1923147	hsa-miR-4698	CLIP-seq
MIRT1923148	hsa-miR-497	CLIP-seq
MIRT1923149	hsa-miR-503	CLIP-seq
MIRT1923150	hsa-miR-548p	CLIP-seq
MIRT1923151	hsa-miR-646	CLIP-seq
MIRT1923137	hsa-miR-1302	CLIP-seq
MIRT1923138	hsa-miR-15a	CLIP-seq
MIRT1923139	hsa-miR-15b	CLIP-seq
MIRT1923140	hsa-miR-16	CLIP-seq
MIRT1923141	hsa-miR-195	CLIP-seq
MIRT756658	hsa-miR-320a	CLIP-seq
MIRT756659	hsa-miR-320b	CLIP-seq
MIRT756660	hsa-miR-320c	CLIP-seq
MIRT756661	hsa-miR-320d	CLIP-seq
MIRT2164669	hsa-miR-3612	CLIP-seq
MIRT2164670	hsa-miR-3663-3p	CLIP-seq
MIRT1923144	hsa-miR-424	CLIP-seq
MIRT1923145	hsa-miR-4298	CLIP-seq
MIRT756672	hsa-miR-4429	CLIP-seq
MIRT2164671	hsa-miR-4443	CLIP-seq
MIRT1923146	hsa-miR-4524	CLIP-seq
MIRT1923148	hsa-miR-497	CLIP-seq
MIRT1923149	hsa-miR-503	CLIP-seq
MIRT2164672	hsa-miR-526b	CLIP-seq
MIRT2164673	hsa-miR-578	CLIP-seq
MIRT1923151	hsa-miR-646	CLIP-seq
MIRT2164674	hsa-miR-650	CLIP-seq
MIRT756646	hsa-miR-1243	CLIP-seq
MIRT2466438	hsa-miR-125a-3p	CLIP-seq
MIRT2466439	hsa-miR-1266	CLIP-seq
MIRT756649	hsa-miR-1276	CLIP-seq
MIRT1923138	hsa-miR-15a	CLIP-seq
MIRT1923139	hsa-miR-15b	CLIP-seq
MIRT1923140	hsa-miR-16	CLIP-seq
MIRT2466440	hsa-miR-1827	CLIP-seq
MIRT1923141	hsa-miR-195	CLIP-seq
MIRT756652	hsa-miR-19a	CLIP-seq
MIRT756653	hsa-miR-19b	CLIP-seq
MIRT2466441	hsa-miR-224	CLIP-seq
MIRT2466442	hsa-miR-23a	CLIP-seq
MIRT2466443	hsa-miR-23b	CLIP-seq
MIRT2466444	hsa-miR-23c	CLIP-seq
MIRT2466445	hsa-miR-3138	CLIP-seq
MIRT2466446	hsa-miR-3189-3p	CLIP-seq
MIRT756658	hsa-miR-320a	CLIP-seq
MIRT756659	hsa-miR-320b	CLIP-seq
MIRT756660	hsa-miR-320c	CLIP-seq
MIRT756661	hsa-miR-320d	CLIP-seq
MIRT2164669	hsa-miR-3612	CLIP-seq
MIRT756664	hsa-miR-3654	CLIP-seq
MIRT2466447	hsa-miR-3664-3p	CLIP-seq
MIRT756666	hsa-miR-3910	CLIP-seq
MIRT2466448	hsa-miR-3934	CLIP-seq
MIRT2466449	hsa-miR-3977	CLIP-seq
MIRT1923144	hsa-miR-424	CLIP-seq
MIRT2466450	hsa-miR-4263	CLIP-seq
MIRT756669	hsa-miR-4311	CLIP-seq
MIRT2466451	hsa-miR-432	CLIP-seq
MIRT756672	hsa-miR-4429	CLIP-seq
MIRT2164671	hsa-miR-4443	CLIP-seq
MIRT2466452	hsa-miR-4462	CLIP-seq
MIRT756674	hsa-miR-4495	CLIP-seq
MIRT2466453	hsa-miR-4518	CLIP-seq
MIRT1923146	hsa-miR-4524	CLIP-seq
MIRT2466454	hsa-miR-4640-3p	CLIP-seq
MIRT756679	hsa-miR-4695-3p	CLIP-seq
MIRT2466455	hsa-miR-4707-3p	CLIP-seq
MIRT2466456	hsa-miR-4717-3p	CLIP-seq
MIRT756682	hsa-miR-4760-3p	CLIP-seq
MIRT2466457	hsa-miR-4787-5p	CLIP-seq
MIRT756684	hsa-miR-486-5p	CLIP-seq
MIRT756685	hsa-miR-494	CLIP-seq
MIRT1923148	hsa-miR-497	CLIP-seq
MIRT2466458	hsa-miR-502-5p	CLIP-seq
MIRT1923149	hsa-miR-503	CLIP-seq
MIRT756688	hsa-miR-548an	CLIP-seq
MIRT2466459	hsa-miR-548b-3p	CLIP-seq
MIRT2466460	hsa-miR-576-5p	CLIP-seq
MIRT756690	hsa-miR-583	CLIP-seq
MIRT2466461	hsa-miR-592	CLIP-seq
MIRT2466462	hsa-miR-597	CLIP-seq
MIRT2466463	hsa-miR-602	CLIP-seq
MIRT756691	hsa-miR-622	CLIP-seq
MIRT1923151	hsa-miR-646	CLIP-seq
MIRT2164674	hsa-miR-650	CLIP-seq
MIRT756692	hsa-miR-711	CLIP-seq
MIRT2466464	hsa-miR-764	CLIP-seq
MIRT2466438	hsa-miR-125a-3p	CLIP-seq
MIRT2466439	hsa-miR-1266	CLIP-seq
MIRT756649	hsa-miR-1276	CLIP-seq
MIRT1923138	hsa-miR-15a	CLIP-seq
MIRT1923139	hsa-miR-15b	CLIP-seq
MIRT1923140	hsa-miR-16	CLIP-seq
MIRT2466440	hsa-miR-1827	CLIP-seq
MIRT1923141	hsa-miR-195	CLIP-seq
MIRT756652	hsa-miR-19a	CLIP-seq
MIRT756653	hsa-miR-19b	CLIP-seq
MIRT2466441	hsa-miR-224	CLIP-seq
MIRT2466442	hsa-miR-23a	CLIP-seq
MIRT2466443	hsa-miR-23b	CLIP-seq
MIRT2466444	hsa-miR-23c	CLIP-seq
MIRT2466445	hsa-miR-3138	CLIP-seq
MIRT756658	hsa-miR-320a	CLIP-seq
MIRT756659	hsa-miR-320b	CLIP-seq
MIRT756660	hsa-miR-320c	CLIP-seq
MIRT756661	hsa-miR-320d	CLIP-seq
MIRT2164669	hsa-miR-3612	CLIP-seq
MIRT2466447	hsa-miR-3664-3p	CLIP-seq
MIRT2466448	hsa-miR-3934	CLIP-seq
MIRT2466449	hsa-miR-3977	CLIP-seq
MIRT1923144	hsa-miR-424	CLIP-seq
MIRT756669	hsa-miR-4311	CLIP-seq
MIRT756672	hsa-miR-4429	CLIP-seq
MIRT2164671	hsa-miR-4443	CLIP-seq
MIRT2466452	hsa-miR-4462	CLIP-seq
MIRT756674	hsa-miR-4495	CLIP-seq
MIRT2466453	hsa-miR-4518	CLIP-seq
MIRT1923146	hsa-miR-4524	CLIP-seq
MIRT2466454	hsa-miR-4640-3p	CLIP-seq
MIRT756679	hsa-miR-4695-3p	CLIP-seq
MIRT2466455	hsa-miR-4707-3p	CLIP-seq
MIRT2466456	hsa-miR-4717-3p	CLIP-seq
MIRT756682	hsa-miR-4760-3p	CLIP-seq
MIRT2466457	hsa-miR-4787-5p	CLIP-seq
MIRT756685	hsa-miR-494	CLIP-seq
MIRT1923148	hsa-miR-497	CLIP-seq
MIRT1923149	hsa-miR-503	CLIP-seq
MIRT2466459	hsa-miR-548b-3p	CLIP-seq
MIRT756690	hsa-miR-583	CLIP-seq
MIRT2466461	hsa-miR-592	CLIP-seq
MIRT2466462	hsa-miR-597	CLIP-seq
MIRT2466463	hsa-miR-602	CLIP-seq
MIRT756691	hsa-miR-622	CLIP-seq
MIRT1923151	hsa-miR-646	CLIP-seq
MIRT2164674	hsa-miR-650	CLIP-seq
MIRT2466464	hsa-miR-764	CLIP-seq

Gene ontology (GO) Show/Hide all (14)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0005515	Function	Protein binding	IPI	25416956
GO:0005524	Function	ATP binding	IEA
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IEA
GO:0005829	Component	Cytosol	TAS
GO:0006629	Process	Lipid metabolic process	IEA
GO:0006631	Process	Fatty acid metabolic process	IEA
GO:0016874	Function	Ligase activity	IEA
GO:0030729	Function	Acetoacetate-CoA ligase activity	IBA
GO:0030729	Function	Acetoacetate-CoA ligase activity	IEA
GO:0030729	Function	Acetoacetate-CoA ligase activity	TAS
GO:0032024	Process	Positive regulation of insulin secretion	IBA
GO:0046951	Process	Ketone body biosynthetic process	TAS

Other IDs

• MIM: 614364
• HGNC: 21298
• e!Ensembl: ENSG00000081760

Protein

• UniProt ID: Q86V21
• Protein name: Acetoacetyl-CoA synthetase (EC 6.2.1.16) (Acyl-CoA synthetase family member 1) (Protein sur-5 homolog)
• Protein function: Converts acetoacetate to acetoacetyl-CoA in the cytosol (By similarity). Ketone body-utilizing enzyme, responsible for the synthesis of cholesterol and fatty acids (By similarity).
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00501	AMP-binding	103 → 546	AMP-binding enzyme	Family
  PF16177	ACAS_N	47 → 105	Acetyl-coenzyme A synthetase N-terminus	Family

• Tissue specificity: TISSUE SPECIFICITY: Highly expressed in kidney, heart and brain, but low in liver. {ECO:0000269|PubMed:12623130}.
• Sequence:

  MSKEERPGREEILECQVMWEPDSKKNTQMDRFRAAVGAACGLALESYDDLYHWSVESYSD
  FWAEFWKFSGIVFSRVYDEVVDTSKGIADVPEWFKGSRLNYAENLLRHKENDRVALYIAR
  EGKEEIVKVTFEELRQEVALFAAAMRKMGVKKGDRVVGYLPNSEHAVEAMLAAASIGAIW
  SSTSPDFGVNGVLDRFSQIQPKLIFSVEAVVYNGKEHNHMEKLQQVVKGLPDLKKVVVIP
  YVSSRENIDLSKIPNSVFLDDFLATGTSEQAPQLEFEQLPFSHPLFIMFSSGTTGAPKCM
  VHSAGGTLIQHLKEHLLHGNMTSSDILLCYTTVGWMMWNWMVSLLATGAAMVLYDGSPLV
  PTPNVLWDLVDRIGITVLVTGAKWLSVLEEKAMKPVETHSLQMLHTILSTGSPLKAQSYE
  YVYRCIKSSILLGSISGGTDIISCFMGHNFSLPVYKGEIQARNLGMAVEAWNEEGKAVWG
  ESGELVCTKPIPCQPTHFWNDENGNKYRKAYFSKFPGIWAHGDYCRINPKTGGIVMLGRS
  DGTLNPNGVRFGSSEIYNIVESFEEVEDSLCVPQYNKYREERVILFLKMASGHAFQPDLV
  KRIRDAIRMGLSARHVPSLILETKGIPYTLNGKKVEVAVKQIIAGKAVEQGGAFSNPETL
  DLYRDIPELQGF

• Sequence length: 672

Pathways

KEGG Pathway	Reactome Pathway
Valine, leucine and isoleucine degradation	Synthesis of Ketone Bodies
Butanoate metabolism
Metabolic pathways

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations Show/Hide Unknown Diseases (15)
Phenotype Name	Clinical Significance	Source	Reference	Evidence Score
Acute myeloid leukemia	Benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BIPOLAR DISORDER	—	GWAS catalog	24322204	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Cervical cancer	Benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Clear cell carcinoma of kidney	Benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Colon adenocarcinoma	Benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Colorectal cancer	Uncertain significance	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Gastric cancer	Benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Hepatocellular carcinoma	Benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Lung cancer	Benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PARKINSON DISEASE	—	GWAS catalog	33111402	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCOLIOSIS	—	GWAS catalog	30019117	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Thyroid cancer, nonmedullary, 1	Benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TREATMENT-RESISTANT HYPERTENSION	—	GWAS catalog	30237584	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uterine carcinosarcoma	Benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uterine corpus endometrial carcinoma	Benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining Show/Hide Text Mining Associations (10)
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	24452951	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	36205594	Stimulate	★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	35924107	Associate	★☆☆☆☆ Found in Text Mining only
Insulin Resistance	Diabetes mellitus, type 2	Pubtator	30913280	Associate	★☆☆☆☆ Found in Text Mining only
Leukemia, Myelocytic, Acute	Leukemia	GWASCAT_DG	27903959		★☆☆☆☆ Found in Text Mining only
Metabolic Syndrome	Metabolic syndrome	Pubtator	30913280	Associate	★☆☆☆☆ Found in Text Mining only
Neuroblastoma	Neuroblastoma	BEFREE	29137983		★☆☆☆☆ Found in Text Mining only
Non-alcoholic Fatty Liver Disease	Non-Alcoholic Fatty Liver Disease	BEFREE	28077733		★☆☆☆☆ Found in Text Mining only
Septicemia	Septicemia	BEFREE	31681299		★☆☆☆☆ Found in Text Mining only
Steatohepatitis	Fatty Liver	BEFREE	28077733		★☆☆☆☆ Found in Text Mining only

Related Genes

Sort by: Blended Diseases Pathways Evidence source

HMGCLL1 3 shared pathwaysValine, leucine and isoleucine degradation, Butanoate metabolism, Synthesis of Ketone Bodies Related via 3 shared pathways including Valine, leucine and isoleucine degradation, Butanoate metabolism. HMGCL 3 shared pathwaysValine, leucine and isoleucine degradation, Butanoate metabolism, Synthesis of Ketone Bodies Related via 3 shared pathways including Valine, leucine and isoleucine degradation, Butanoate metabolism. HMGCS2 3 shared pathwaysValine, leucine and isoleucine degradation, Butanoate metabolism, Synthesis of Ketone Bodies Related via 3 shared pathways including Valine, leucine and isoleucine degradation, Butanoate metabolism. OXCT1 2 shared pathwaysValine, leucine and isoleucine degradation, Butanoate metabolism Related via 2 shared pathways including Valine, leucine and isoleucine degradation, Butanoate metabolism. OXCT2 2 shared pathwaysValine, leucine and isoleucine degradation, Butanoate metabolism Related via 2 shared pathways including Valine, leucine and isoleucine degradation, Butanoate metabolism.

Related Gene	Shared Diseases	Shared Disease Names	Shared Pathways	Shared Pathway Names	Shared Evidence Sources	Shared Evidence Names
HMGCLL1	0	[]	3	["Valine, leucine and isoleucine degradation","Butanoate metabolism","Synthesis of Ketone Bodies"]	0	[]
HMGCL	0	[]	3	["Valine, leucine and isoleucine degradation","Butanoate metabolism","Synthesis of Ketone Bodies"]	0	[]
HMGCS2	0	[]	3	["Valine, leucine and isoleucine degradation","Butanoate metabolism","Synthesis of Ketone Bodies"]	0	[]
OXCT1	0	[]	2	["Valine, leucine and isoleucine degradation","Butanoate metabolism"]	0	[]
OXCT2	0	[]	2	["Valine, leucine and isoleucine degradation","Butanoate metabolism"]	0	[]

Diseases Linked via Similar Genes

Colorectal adenoma Linked via 1 of 5 related genesHMGCLL1 Colorectal cancer Linked via 1 of 5 related genesHMGCLL1 Gout Linked via 1 of 5 related genesHMGCLL1 Obesity Linked via 1 of 5 related genesHMGCLL1 Vesicoureteral reflux Linked via 1 of 5 related genesHMGCLL1

Disease	Linked Via (Gene Count)	Linked Via (Gene Names)
Colorectal adenoma	1	["HMGCLL1"]
Colorectal cancer	1	["HMGCLL1"]
Gout	1	["HMGCLL1"]
Obesity	1	["HMGCLL1"]
Vesicoureteral reflux	1	["HMGCLL1"]