Subtype of: Salivary gland neoplasms

Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
salivary duct carcinoma	MONDO_0044915	RBM10	Unknown	28481359	Open Targets	—
		RET	Unknown	27103403	Open Targets	MAPK signaling pathway Calcium signaling pathway PI3K-Akt signaling pathway +6 more
		RGS7	Unknown	34011559	Open Targets	G alpha (i) signalling events Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
		RICTOR	Unknown	34011559	Open Targets	mTOR signaling pathway PIP3 activates AKT signaling CD28 dependent PI3K/Akt signaling +3 more
		ROBO2	Unknown	34011559	Open Targets	Axon guidance Signaling by ROBO receptors Regulation of commissural axon pathfinding by SLIT and ROBO
		ROS1	Unknown	34011559	Open Targets	—
		RXRA	Unknown	27103403	Open Targets	PPAR signaling pathway Efferocytosis PI3K-Akt signaling pathway +39 more
		SDHC	Unknown	34011559	Open Targets	Citrate cycle (TCA cycle) Oxidative phosphorylation Metabolic pathways +12 more
		SETBP1	Unknown	34011559	Open Targets	—
		SETD1B	Unknown	27103403	Open Targets	Lysine degradation Metabolic pathways PKMTs methylate histone lysines +1 more
		SETD2	Unknown	27334835	Open Targets	Lysine degradation Metabolic pathways PKMTs methylate histone lysines
		SF3B1	Unknown	27103403	Open Targets	Spliceosome B-WICH complex positively regulates rRNA expression mRNA Splicing - Major Pathway +1 more
		SMAD3	Unknown	34011559	Open Targets	FoxO signaling pathway Cell cycle Endocytosis +34 more
		SMAD4	Unknown	27103403 26053092	Open Targets	FoxO signaling pathway Hormone signaling Cell cycle +30 more
		SMARCA4	Unknown	27103403	Open Targets	ATP-dependent chromatin remodeling Thermogenesis Hepatocellular carcinoma +6 more
		SMARCD1	Unknown	27334835	Open Targets	ATP-dependent chromatin remodeling Thermogenesis Hepatocellular carcinoma +2 more
		SMO	Unknown	27103403	Open Targets	Hedgehog signaling pathway Axon guidance Pathways in cancer +6 more
		SPEN	Unknown	27334835	Open Targets	Notch signaling pathway
		STAG2	Unknown	27103403	Open Targets	Cell cycle Separation of Sister Chromatids Establishment of Sister Chromatid Cohesion +4 more
		STAT3	Unknown	34011559	Open Targets	EGFR tyrosine kinase inhibitor resistance Chemokine signaling pathway HIF-1 signaling pathway +53 more
		STAT5B	Unknown	29420467 28481359	Open Targets	ErbB signaling pathway Chemokine signaling pathway Hormone signaling +28 more
		TBL1XR1	Unknown	27103403	Open Targets	Wnt signaling pathway RORA activates gene expression PPARA activates gene expression +11 more
		TENT5C	Unknown	28481359 27442865	Open Targets	—
		TET1	Unknown	27103403	Open Targets	—
		TET2	Unknown	28481359 27334835	Open Targets	—
		TLX1	Unknown	27103403	Open Targets	Transcriptional misregulation in cancer
		TNRC18	Unknown	27103403	Open Targets	—
		TP53	Unknown	32557577 34036229 31745978 27103403 27334835 29420467 26053092 34011559 27379604 28481359 27442865	Open Targets	Endocrine resistance Platinum drug resistance MAPK signaling pathway +85 more
		TRIM24	Unknown	34011559	Open Targets	Signaling by cytosolic FGFR1 fusion mutants Signaling by FGFR1 in disease Signaling by BRAF and RAF fusions
		TSC1	Unknown	27103403	Open Targets	Phospholipase D signaling pathway Autophagy - animal mTOR signaling pathway +15 more
		TSC2	Unknown	27103403	Open Targets	Phospholipase D signaling pathway p53 signaling pathway Autophagy - animal +19 more
		TSHR	Unknown	27103403 28481359 27442865	Open Targets	cAMP signaling pathway Neuroactive ligand-receptor interaction Hormone signaling +6 more
		UBR5	Unknown	34011559	Open Targets	Ubiquitin mediated proteolysis
		USP44	Unknown	27103403	Open Targets	Ub-specific processing proteases
		USP8	Unknown	27103403	Open Targets	Mitophagy - animal Endocytosis Cushing syndrome +4 more
		WWTR1	Unknown	27103403	Open Targets	Hippo signaling pathway Hippo signaling pathway - multiple species Signaling by Hippo +5 more
		XPC	Unknown	27103403	Open Targets	Nucleotide excision repair SUMOylation of DNA damage response and repair proteins DNA Damage Recognition in GG-NER +1 more
		ZFHX3	Unknown	27103403 34011559 28481359 27442865	Open Targets	Signaling pathways regulating pluripotency of stem cells RUNX3 regulates CDKN1A transcription
		ZNF429	Unknown	34011559	Open Targets	Generic Transcription Pathway
		ZRSR2	Unknown	34011559	Open Targets	mRNA Splicing - Minor Pathway

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Salivary duct carcinoma

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