Subtype of: Salivary gland neoplasms

Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
salivary duct carcinoma	MONDO_0044915	ABL1	Unknown	27103403	Open Targets	ErbB signaling pathway Ras signaling pathway Cell cycle +17 more
		ACVR2A	Unknown	34036229	Open Targets	Cytokine-cytokine receptor interaction TGF-beta signaling pathway Signaling pathways regulating pluripotency of stem cells +3 more
		AFF1	Unknown	34011559	Open Targets	Transcriptional misregulation in cancer
		AFF4	Unknown	34011559	Open Targets	Viral life cycle - HIV-1 Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events +1 more
		AKAP9	Unknown	27103403	Open Targets	Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes +7 more
		AKT1	Unknown	31745978 26053092 27103403	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +131 more
		ALK	Unknown	26053092 27103403 28481359 27442865	Open Targets	Pathways in cancer Non-small cell lung cancer PD-L1 expression and PD-1 checkpoint pathway in cancer
		AMER1	Unknown	34011559	Open Targets	Degradation of beta-catenin by the destruction complex Beta-catenin phosphorylation cascade Disassembly of the destruction complex and recruitment of AXIN to the membrane +8 more
		ANK1	Unknown	27103403	Open Targets	Proteoglycans in cancer Interaction between L1 and Ankyrins Neurofascin interactions +1 more
		APC	Unknown	27334835	Open Targets	Wnt signaling pathway Hippo signaling pathway Signaling pathways regulating pluripotency of stem cells +28 more
		AR	Unknown	37427101	Open Targets	Oocyte meiosis Pathways in cancer Chemical carcinogenesis - receptor activation +7 more
		ARHGAP35	Unknown	27103403	Open Targets	Focal adhesion Platelet activation Leukocyte transendothelial migration +4 more
		ARID1A	Unknown	37427101 27103403 29420467 28481359 27442865	Open Targets	ATP-dependent chromatin remodeling Thermogenesis Hepatocellular carcinoma +2 more
		ARID1B	Unknown	34011559 28481359	Open Targets	ATP-dependent chromatin remodeling Thermogenesis Hepatocellular carcinoma +2 more
		ASXL1	Unknown	27103403 28481359 27442865 27334835	Open Targets	Polycomb repressive complex UCH proteinases
		ATM	Unknown	28481359	Open Targets	Platinum drug resistance Homologous recombination NF-kappa B signaling pathway +33 more
		ATR	Unknown	27103403 34011559 28481359 27442865	Open Targets	Fanconi anemia pathway Cell cycle p53 signaling pathway +13 more
		BAP1	Unknown	34011559 27334835	Open Targets	Polycomb repressive complex UCH proteinases Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
		BARD1	Unknown	28481359 27442865	Open Targets	Homologous recombination HDR through Single Strand Annealing (SSA) HDR through Homologous Recombination (HRR) +11 more
		BAZ1A	Unknown	27103403 34011559	Open Targets	ATP-dependent chromatin remodeling
		BCL9L	Unknown	27103403	Open Targets	Formation of the beta-catenin:TCF transactivating complex Deactivation of the beta-catenin transactivating complex
		BCORL1	Unknown	34011559	Open Targets	Polycomb repressive complex
		BIRC6	Unknown	34011559	Open Targets	Ubiquitin mediated proteolysis Autophagy - animal Apoptosis - multiple species
		BMPR1A	Unknown	27103403	Open Targets	Cytokine-cytokine receptor interaction Hormone signaling TGF-beta signaling pathway +4 more
		BRAF	Unknown	31745978 27103403 27334835 23186780 26053092 28481359	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +52 more
		BRCA1	Unknown	28481359 27334835	Open Targets	Platinum drug resistance Homologous recombination Fanconi anemia pathway +19 more
		BRCA2	Unknown	27103403 28481359 27442865 27334835	Open Targets	Homologous recombination Fanconi anemia pathway Pathways in cancer +7 more
		BRIP1	Unknown	29420467 28481359 27334835	Open Targets	Homologous recombination Fanconi anemia pathway HDR through Single Strand Annealing (SSA) +8 more
		CARD11	Unknown	28481359 27442865	Open Targets	NF-kappa B signaling pathway T cell receptor signaling pathway B cell receptor signaling pathway +4 more
		CASP8	Unknown	27334835	Open Targets	Platinum drug resistance p53 signaling pathway Apoptosis +53 more
		CASP9	Unknown	34011559	Open Targets	Platinum drug resistance p53 signaling pathway PI3K-Akt signaling pathway +39 more
		CDH1	Unknown	27103403 33538422 29420467 28481359 27442865	Open Targets	Rap1 signaling pathway Apelin signaling pathway Hippo signaling pathway +15 more
		CDH11	Unknown	27103403	Open Targets	Adherens junctions interactions
		CDH17	Unknown	27103403	Open Targets	Gastric cancer Adherens junctions interactions
		CDK12	Unknown	27103403	Open Targets	TP53 Regulates Transcription of DNA Repair Genes
		CDKN1A	Unknown	28481359	Open Targets	Endocrine resistance Platinum drug resistance ErbB signaling pathway +56 more
		CDKN2A	Unknown	27103403 27334835 37427101 10534174 28481359 27442865	Open Targets	Endocrine resistance Platinum drug resistance Cell cycle +33 more
		CHD2	Unknown	27334835	Open Targets	—
		CIC	Unknown	27103403 34011559	Open Targets	Spinocerebellar ataxia
		CNBD1	Unknown	34011559	Open Targets	—
		CNTRL	Unknown	27103403	Open Targets	Signaling by cytosolic FGFR1 fusion mutants Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes +6 more
		CREB1	Unknown	34011559	Open Targets	cGMP-PKG signaling pathway cAMP signaling pathway Efferocytosis +53 more
		CRNKL1	Unknown	34011559	Open Targets	Spliceosome mRNA Splicing - Major Pathway
		CRTC1	Unknown	17437281	Open Targets	Human T-cell leukemia virus 1 infection Transcriptional activation of mitochondrial biogenesis Circadian Clock
		CSMD3	Unknown	27103403	Open Targets	—
		CTNNB1	Unknown	27103403	Open Targets	Rap1 signaling pathway Wnt signaling pathway Hippo signaling pathway +51 more
		CTNND2	Unknown	27103403	Open Targets	Wnt signaling pathway
		CUL3	Unknown	27103403	Open Targets	Ubiquitin mediated proteolysis Hedgehog signaling pathway Degradation of DVL +4 more
		DDX3X	Unknown	27103403	Open Targets	RIG-I-like receptor signaling pathway Hepatitis B Viral carcinogenesis +1 more
		DROSHA	Unknown	27103403	Open Targets	Ribosome biogenesis in eukaryotes Proteoglycans in cancer MicroRNA (miRNA) biogenesis

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Salivary duct carcinoma

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