Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
PARKINSON DISEASE	MONDO_0005180 C0030567 MESH:D010300	FGD4	Unknown	31701892	GWAS catalog	NRAGE signals death through JNK Rho GTPase cycle G alpha (12/13) signalling events
		FSTL5	Unknown	39503264	GWAS catalog	—
		FYN	Unknown	32310270 38155330	GWAS catalog	Sphingolipid signaling pathway Phospholipase D signaling pathway Axon guidance +47 more
		GABRG2	Unknown	33987465	GWAS catalog	Neuroactive ligand-receptor interaction Retrograde endocannabinoid signaling GABAergic synapse +3 more
		GABRG3	Unknown	19772629	GWAS catalog	Neuroactive ligand-receptor interaction Retrograde endocannabinoid signaling GABAergic synapse +3 more
		GAK	Unknown	18985386 20711177 27182965 31701892 38155330	CTD, Disgenet, GWAS catalog	Golgi Associated Vesicle Biogenesis Clathrin-mediated endocytosis
		GALNT9	Unknown	31701892 38155330	GWAS catalog	Mucin type O-glycan biosynthesis Other types of O-glycan biosynthesis Metabolic pathways +1 more
		GAS7	Unknown	39503264	GWAS catalog	—
		GBA2	Unknown	37842648	GWAS catalog	Other glycan degradation Sphingolipid metabolism Metabolic pathways +1 more
		GBF1	Unknown	28892059 31701892 36759515	GWAS catalog	Endocytosis trans-Golgi Network Vesicle Budding VxPx cargo-targeting to cilium +2 more
		GCH1	Unknown	25064009 27182965 28892059 31701892 32201043 36759515 38155330 39080267	GWAS catalog	Folate biosynthesis Metabolic pathways Biosynthesis of cofactors +1 more
		GDF5	Unknown	—	Disgenet	Cytokine-cytokine receptor interaction TGF-beta signaling pathway Hippo signaling pathway +1 more
		GDNF	Unknown	11031079 16324109	CTD, Disgenet	MAPK signaling pathway Calcium signaling pathway PI3K-Akt signaling pathway +2 more
		GFAP	Unknown	19276553	CTD, Disgenet	JAK-STAT signaling pathway Nuclear signaling by ERBB4
		GFPT2	Unknown	20070850	GWAS catalog	Alanine, aspartate and glutamate metabolism Amino sugar and nucleotide sugar metabolism Metabolic pathways +4 more
		GIGYF2	Unknown	—	Disgenet	—
		GJA5	Unknown	37560120	GWAS catalog	Gap junction assembly
		GNA12	Unknown	37842648	GWAS catalog	MAPK signaling pathway cGMP-PKG signaling pathway Sphingolipid signaling pathway +11 more
		GPATCH2	Unknown	39503264	GWAS catalog	—
		GPM6B	Unknown	33583074	GWAS catalog	—
		GPNMB	Unknown	25064009 28892059 31701892 38155330	GWAS catalog	PTK6 promotes HIF1A stabilization
		GPR19	Unknown	33111402	GWAS catalog	—
		GPR32	Unknown	33111402	GWAS catalog	G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production
		GPR65	Unknown	28892059 31701892 32201043	GWAS catalog	Class A/1 (Rhodopsin-like receptors) G alpha (q) signalling events
		GPRIN3	Unknown	31701892 32201043 38155330	GWAS catalog	—
		GPX6	Unknown	39503264	GWAS catalog	Glutathione metabolism Metabolic pathways Thyroid hormone synthesis +4 more
		GRK6	Unknown	—	Disgenet	Chemokine signaling pathway Endocytosis Morphine addiction +1 more
		GSTA4	Unknown	16510128	CTD, Disgenet	Glutathione metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450 +10 more
		GSTM1	Unknown	17449559	CTD, Disgenet	Glutathione metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450 +10 more
		GSTO1	Unknown	—	Disgenet	Glutathione metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450 +13 more
		GSTO2	Unknown	—	Disgenet	Glutathione metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450 +11 more
		GSTT1	Unknown	—	Disgenet	Glutathione metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450 +10 more
		GUCY1A1	Unknown	37842648	GWAS catalog	Purine metabolism Metabolic pathways cGMP-PKG signaling pathway +8 more
		GUCY1A2	Unknown	33111402	GWAS catalog	Purine metabolism Metabolic pathways cGMP-PKG signaling pathway +8 more
		GXYLT1	Unknown	31701892	GWAS catalog	Other types of O-glycan biosynthesis
		HASPIN	Unknown	34064523	GWAS catalog	—
		HBG1	Unknown	25475535	CTD, Disgenet	Factors involved in megakaryocyte development and platelet production
		HCAR2	Unknown	38155330	GWAS catalog	cAMP signaling pathway Hydroxycarboxylic acid-binding receptors Class A/1 (Rhodopsin-like receptors) +1 more
		HEATR6	Unknown	36759515	GWAS catalog	—
		HFE	Unknown	16824219	CTD, Disgenet	TGF-beta signaling pathway Transferrin endocytosis and recycling
		HGF	Unknown	16791285	CTD, Disgenet	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +29 more
		HIP1R	Unknown	31701892 36759515 38155330 39080267	GWAS catalog	Golgi Associated Vesicle Biogenesis Clathrin-mediated endocytosis
		HLA-DQA1	Unknown	27182965 31701892 32201043 39080267	GWAS catalog	Phagosome Cell adhesion molecules Antigen processing and presentation +28 more
		HLA-DQB1	Unknown	25064009 28892059 31660654	GWAS catalog	Phagosome Cell adhesion molecules Antigen processing and presentation +28 more
		HLA-DRB1	Unknown	27182965 31701892 32201043 39080267	Disgenet, GWAS catalog	Phagosome Cell adhesion molecules Antigen processing and presentation +28 more
		HLA-DRB5	Unknown	27713094	CTD	Phagosome Cell adhesion molecules Antigen processing and presentation +28 more
		HMGCR	Unknown	—	Disgenet	Terpenoid backbone biosynthesis Metabolic pathways AMPK signaling pathway +5 more
		HMOX1	Unknown	21318773	CTD, Disgenet	Porphyrin metabolism Metabolic pathways HIF-1 signaling pathway +11 more
		HNMT	Unknown	—	Disgenet	Histidine metabolism Metabolic pathways Histidine catabolism
		HSPA1A	Unknown	15585408	CTD, Disgenet	Spliceosome MAPK signaling pathway Protein processing in endoplasmic reticulum +16 more
PARKINSON DISEASE 11	MESH:C564345	GIGYF2	Unknown	—	CTD	—
PARKINSON DISEASE 11, AUTOSOMAL DOMINANT, SUSCEPTIBILITY TO	MONDO:0011896	GIGYF2	Unknown	—	ClinVar, GenCC	—
PARKINSONIAN DISORDERS	C0242422 MESH:D020734	GCH1	Unknown	—	Disgenet	Folate biosynthesis Metabolic pathways Biosynthesis of cofactors +1 more
		GDNF	Unknown	12213621 9266731	CTD, Disgenet	MAPK signaling pathway Calcium signaling pathway PI3K-Akt signaling pathway +2 more
		HSPA1A	Unknown	—	Disgenet	Spliceosome MAPK signaling pathway Protein processing in endoplasmic reticulum +16 more

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Parkinson disease

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